Pain and itch in a dish
(Scripps Research Institute) A team led by scientists from The Scripps Research Institute has found a simple method to convert human skin cells into the specialized neurons that detect pain, itch, touch and other bodily sensations. These neurons are also affected by spinal cord injury and involved in Friedreich's ataxia, a devastating and currently incurable neurodegenerative disease that largely strikes children. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 24, 2014 Category: Global & Universal Source Type: news
Non-profit Foundation Fighting Friedreich’s Ataxia Names Catrike Partner of the Year
A tricycle design and manufacturing company, Catrike, has been dramatically improving the lives of individuals affected by the rare and genetic disease, Friedreich’s Ataxia (FA). Recognizing the company's many contributions to the FA community, Catrike has been honored as Partner of the Year by the Friedreich’s Ataxia Research Alliance. (Source: Disabled World)
Source: Disabled World - November 9, 2014 Category: Disability Tags: Mobility Aids Source Type: news
Non-profit Foundation Fighting Friedreich's Ataxia Names Catrike Partner of the Year
Catrike is improving lives of people in the FA community by increasing access to trikes, which help people with FA remain active (Source: Disabled World)
Source: Disabled World - November 9, 2014 Category: Disability Tags: Mobility Aids/Devices Source Type: news
Cerebellar Ataxia Diagnosis Aided by Exome SequencingCerebellar Ataxia Diagnosis Aided by Exome Sequencing
Clinical exome sequencing is proving to be highly useful in the genetic diagnosis of adult and sporadic-onset cerebellar ataxia and should be considered routine in the evaluation of such patients. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - October 9, 2014 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news
Event Gathers World-Renowned Researchers and Community Leaders to Find...
Scientists, physicians, patients, families, and community leaders from around the world will join together in Tampa Bay from September 4-6 for the Friedreich’s Ataxia Research Alliance’s (FARA) sixth...(PRWeb September 02, 2014)Read the full story at http://www.prweb.com/releases/2014/09/prweb12139752.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - September 4, 2014 Category: Pharmaceuticals Source Type: news
Methoxetamine: a ketamine analog that is NOT bladder friendly
3.5 out of 5 stars
Methoxetamine — a novel recreational drug with potent hallucinogenic properties. Zawilska JB. Toxicol Lett 2014 Aug 13. pii: S0378-4274(14)01298-3. doi: 10.1016/j.toxlet.2014.08.011. [Epub ahead of print]
Abstract
Methoxetamine (MXE) is a structural analog of ketamine, with effects that are similar but more intense and longer-lasting. Street names include:
MXE
Mexxy
M-ket
MEX
Kmax
Special M
MA
“Legal ketamine”
Minx
Jipper
Roflcoptr
Since chronic exposure to ketamine is known to cause ulcerative cystitis, MXE is sometimes touted as “bladder friendly.” However, lack of clini...
Source: The Poison Review - August 20, 2014 Category: Toxicology Authors: Leon Tags: Medical bladder toxicity genitourinary toxicity ketamine methoxetamine MXE Source Type: news
Training balance with opto-kinetic stimuli in the home: a randomized controlled feasibility study in people with pure cerebellar disease - Bunn LM, Marsden JF, Giunti P, Day BL.
OBJECTIVE: To investigate the feasibility of a randomized controlled trial of a home-based balance intervention for people with cerebellar ataxia. DESIGN: A randomized controlled trial design. SETTING: Intervention and assessment took place in the ... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - August 8, 2014 Category: Global & Universal Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
Genetics Home Reference: dilated cardiomyopathy with ataxia syndrome
http://ghr.nlm.nih.gov/condition/dilated-cardiomyopathy-with-ataxia-syndrome (Source: NLM General Announcements)
Source: NLM General Announcements - August 5, 2014 Category: Databases & Libraries Source Type: news
What Is Ataxia and What Causes It?
Ataxia in common usage means unsteady gait. More ... (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - August 5, 2014 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news
Paralytic shellfish poisoning: a case series - Hurley W, Wolterstorff C, MacDonald R, Schultz D.
We describe a case series of seven patients presenting to an emergency department with symptoms of paralytic shellfish poisoning. They developed varying degrees of nausea, vomiting, diarrhea, weakness, ataxia and paresthesias after eating mussels harvested... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - July 26, 2014 Category: Global & Universal Tags: Home and Consumer Product Safety Source Type: news
The human δ2 glutamate receptor gene is not mutated in spinocerebellar ataxia patients
(Neural Regeneration Research) Recent studies have demonstrated that glutamate receptor δ2 gene (GRID2) is closely related to cerebellar functions in mice. This gene is predominantly located in postsynaptic dendrites of parallel fiber-Purkinje cell synapses in the cerebellum and contains potential fragile sites within large introns. These fragile sites easily develop spontaneous mutation, which leads to Purkinje cell death, contributing to the manifestation of spinocerebellar ataxia in mice. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 17, 2014 Category: Global & Universal Source Type: news
Mussel Beach: Paralytic Shellfish Poisoning
3 out of 5 stars
Paralytic Shellfish Poisoning: A Case Series. Hurley W et al. West J Emerg Med 2014 Jul;15:378-381.
Full Text
Paralytic shellfish poisoning (PSP)is caused by saxitoxin, an alkaloid produced by certain marine dinoflagellates and released during algae blooms that produce a so-called “red tide.” (Actually, the water can be various colors, or even clear, during these blooms.) The toxin is then taken up and concentrated by filter-feeding mollusks, including oysters, clams and mussels.
Like tetrodotoxin, saxitoxin is a sodium-channel blocker. It causes mostly neurotoxicity and gastrointestinal s...
Source: The Poison Review - July 11, 2014 Category: Toxicology Authors: Leon Tags: Medical dinoflagellate marine toxicity mollusks mussels neurotoxicity paralytic shellfish poisoning saxitoxin Source Type: news
Eat More Gluten: The Diet Fad Must Die
If you’ve got a hankering to make some money, now might be a good time to trademark a brand name for gluten-free salt. If they’re all taken, try gluten-free sugar or gluten-free water. And if they’re gone too, well, there’s still gluten-free shoes.
MoreWhy Organic is the Right Choice for ParentsKraft Recalls Velveeta Cheese Because It Doesn’t Have Enough PreservativesBloody Rampage: Where Will Iraq's Militants Strike Next? NBC NewsJeremy Meeks, 'Hot Convict,' Used To Look Pretty Different Huffington PostHappy Marsiversary! Curiosity Rover Snaps Selfie NBC NewsWhat’s that? None of those t...
Source: TIME: Top Science and Health Stories - June 23, 2014 Category: Science Authors: Jeffrey Kluger Tags: Uncategorized barley behavior celiac disease fads Food Gluten gluten ataxia gluten free gluten sensitivity gluten-sensitive Nutrition rye wheat Source Type: news
Gene critical for development of brain motor center found
A research team describes a gene called Snf2h, which is found in our brain's neural stem cells and functions as a master regulator. When they removed this gene early on in a mouse's development, its cerebellum only grew to one-third the normal size. It also had difficulty walking, balancing and coordinating its movements, something called cerebellar ataxia that is a component of many neurodegenerative diseases. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - June 22, 2014 Category: Science Source Type: news
Researchers find gene critical for development of brain motor center
(Ottawa Hospital Research Institute) In Nature Communications, an Ottawa-led team describes a gene called Snf2h, which is found in our brain's neural stem cells and functions as a master regulator. When they removed this gene early on in a mouse's development, its cerebellum only grew to one-third the normal size. It also had difficulty walking, balancing and coordinating its movements, something called cerebellar ataxia that is a component of many neurodegenerative diseases. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 20, 2014 Category: Global & Universal Source Type: news
