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The Influence of Sex Hormones and X Chromosome in Immune Responses
Curr Top Microbiol Immunol. 2023;441:21-59. doi: 10.1007/978-3-031-35139-6_2.ABSTRACTMales and females differ in their susceptibility to develop autoimmunity and allergy but also in their capacity to cope with infections and cancers. Cellular targets and molecular pathways underlying sexual dimorphism in immunity have started to emerge and appeared multifactorial. It became increasingly clear that sex-linked biological factors have important impact on the development, tissue maintenance and effector function acquisition of distinct immune cell populations, thereby regulating multiple layers of innate or adaptive immunity t...
Source: Current Topics in Microbiology and Immunology - September 11, 2023 Category: Microbiology Authors: Nina Anesi Charles-Henry Miquel Sophie Laffont Jean-Charles Gu éry Source Type: research

Risk factors predisposing children to food allergies
CONCLUSION: The most important aspect of this study was that it separately identified prenatal, neonatal, and postnatal risk factors for IgE- and non-IgE-mediated food allergies.PMID:37695233 | DOI:10.15586/aei.v51i5.937
Source: Allergologia et Immunopathologia - September 11, 2023 Category: Allergy & Immunology Authors: Ecem Firtin Is ılay Turan Deniz Ozceker Betul Buyuktiryaki Gonca Hancioglu Selami Ulas Sezin Naiboglu Ci ğdem Aydogmus Recep Sancak Mehmet Halil Celiksoy Source Type: research

Does the severity of atopic dermatitis change with allergic sensitization? Is it real or a myth?
CONCLUSION: While guidelines recommend investigating food allergies in moderate to severe AD, this study found no significant difference in the relationship between AD severity and the presence of FA. However, inhalant allergen sensitivity was linked to increased AD severity. Therefore, a comprehensive patient history should include an evaluation of food allergies in children with AD, regardless of disease severity. Elimination and provocation tests related to suspected food items should be performed, and allergenic foods should be removed from the diet if they are found to contribute to the allergy.PMID:37695232 | DOI:10.15586/aei.v51i5.921
Source: Allergologia et Immunopathologia - September 11, 2023 Category: Allergy & Immunology Authors: Serdar Al Suna Asilsoy Özge Atay Özge Kangallı Nevin Uzuner Source Type: research

Quality of life in children with food allergies, psychiatric symptoms, and caregiving burden of their mothers
CONCLUSION: In order to develop a multidisciplinary approach for children with food allergies, we conceived as appropriate to inform their families about the difficulties of caregiving and psychosocial disorders that could develop over time. They also must be informed to take preventive measures as well as the medical aspects of their children's disease.PMID:37695230 | DOI:10.15586/aei.v51i5.860
Source: Allergologia et Immunopathologia - September 11, 2023 Category: Allergy & Immunology Authors: N ülüfer Kılıç Şuheda Kaya G ülay Taşçı Filiz Özsoy Mehmet K ılıç Source Type: research

The Influence of Sex Hormones and X Chromosome in Immune Responses
Curr Top Microbiol Immunol. 2023;441:21-59. doi: 10.1007/978-3-031-35139-6_2.ABSTRACTMales and females differ in their susceptibility to develop autoimmunity and allergy but also in their capacity to cope with infections and cancers. Cellular targets and molecular pathways underlying sexual dimorphism in immunity have started to emerge and appeared multifactorial. It became increasingly clear that sex-linked biological factors have important impact on the development, tissue maintenance and effector function acquisition of distinct immune cell populations, thereby regulating multiple layers of innate or adaptive immunity t...
Source: Current Topics in Microbiology and Immunology - September 11, 2023 Category: Microbiology Authors: Nina Anesi Charles-Henry Miquel Sophie Laffont Jean-Charles Gu éry Source Type: research

Does the severity of atopic dermatitis change with allergic sensitization? Is it real or a myth?
CONCLUSION: While guidelines recommend investigating food allergies in moderate to severe AD, this study found no significant difference in the relationship between AD severity and the presence of FA. However, inhalant allergen sensitivity was linked to increased AD severity. Therefore, a comprehensive patient history should include an evaluation of food allergies in children with AD, regardless of disease severity. Elimination and provocation tests related to suspected food items should be performed, and allergenic foods should be removed from the diet if they are found to contribute to the allergy.PMID:37695232 | DOI:10.15586/aei.v51i5.921
Source: Allergologia et Immunopathologia - September 11, 2023 Category: Allergy & Immunology Authors: Serdar Al Suna Asilsoy Özge Atay Özge Kangallı Nevin Uzuner Source Type: research

Quality of life in children with food allergies, psychiatric symptoms, and caregiving burden of their mothers
CONCLUSION: In order to develop a multidisciplinary approach for children with food allergies, we conceived as appropriate to inform their families about the difficulties of caregiving and psychosocial disorders that could develop over time. They also must be informed to take preventive measures as well as the medical aspects of their children's disease.PMID:37695230 | DOI:10.15586/aei.v51i5.860
Source: Allergologia et Immunopathologia - September 11, 2023 Category: Allergy & Immunology Authors: N ülüfer Kılıç Şuheda Kaya G ülay Taşçı Filiz Özsoy Mehmet K ılıç Source Type: research

Prevalence and time trends of symptoms of allergic rhinitis and rhinoconjunctivitis in Spanish children: Global Asthma Network (GAN) study
CONCLUSIONS: There has been a stabilisation of rhinitis, rhinoconjunctivitis and nasal allergy in schoolchildren that slows the previous upward trend of ISAAC; and a slight non-significant increase in rhinoconjunctivitis and nasal allergy in adolescents. The variability found in adolescents would require local research to be better understood.PMID:37695222 | DOI:10.15586/aei.v51i1.711
Source: Allergologia et Immunopathologia - September 11, 2023 Category: Allergy & Immunology Authors: Alberto Bercedo-Sanz Antonela Mart ínez-Torres Angel L ópez-Silvarrey Varela Francisco Javier Pellegrini Belinch ón Ines Aguinaga-Ontoso Carlos Gonz ález Díaz Luis Garc ía-Marcos Grupo Gan Spain Source Type: research

Risk factors predisposing children to food allergies
CONCLUSION: The most important aspect of this study was that it separately identified prenatal, neonatal, and postnatal risk factors for IgE- and non-IgE-mediated food allergies.PMID:37695233 | DOI:10.15586/aei.v51i5.937
Source: Allergologia et Immunopathologia - September 11, 2023 Category: Allergy & Immunology Authors: Ecem Firtin Is ılay Turan Deniz Ozceker Betul Buyuktiryaki Gonca Hancioglu Selami Ulas Sezin Naiboglu Ci ğdem Aydogmus Recep Sancak Mehmet Halil Celiksoy Source Type: research

Does the severity of atopic dermatitis change with allergic sensitization? Is it real or a myth?
CONCLUSION: While guidelines recommend investigating food allergies in moderate to severe AD, this study found no significant difference in the relationship between AD severity and the presence of FA. However, inhalant allergen sensitivity was linked to increased AD severity. Therefore, a comprehensive patient history should include an evaluation of food allergies in children with AD, regardless of disease severity. Elimination and provocation tests related to suspected food items should be performed, and allergenic foods should be removed from the diet if they are found to contribute to the allergy.PMID:37695232 | DOI:10.15586/aei.v51i5.921
Source: Allergologia et Immunopathologia - September 11, 2023 Category: Allergy & Immunology Authors: Serdar Al Suna Asilsoy Özge Atay Özge Kangallı Nevin Uzuner Source Type: research

Quality of life in children with food allergies, psychiatric symptoms, and caregiving burden of their mothers
CONCLUSION: In order to develop a multidisciplinary approach for children with food allergies, we conceived as appropriate to inform their families about the difficulties of caregiving and psychosocial disorders that could develop over time. They also must be informed to take preventive measures as well as the medical aspects of their children's disease.PMID:37695230 | DOI:10.15586/aei.v51i5.860
Source: Allergologia et Immunopathologia - September 11, 2023 Category: Allergy & Immunology Authors: N ülüfer Kılıç Şuheda Kaya G ülay Taşçı Filiz Özsoy Mehmet K ılıç Source Type: research

Outcomes and factors associated with tolerance in infants with non-IgE-mediated cow's milk allergy with gastrointestinal manifestations
CONCLUSIONS: In infants with non-IgE-mediated CMPA with gastrointestinal manifestations, the use of cow's milk-based formula, a history of other food allergies, and hematochezia and diarrhea upon initial presentation were associated factors for the later achievement of tolerance.PMID:37696495 | DOI:10.1016/j.jped.2023.08.003
Source: Jornal de Pediatria - September 11, 2023 Category: Pediatrics Authors: Pr íscila da Silva Pereira Vasconcelos Ana Laura Mendes Becker Andrade Natascha Silva Sandy Juliana Corr êa Campos Barreto Gabriela Souza Gomez Adriana Gut Lopes Riccetto Elizete Aparecida Lomazi Maria Ângela Bellomo-Brandão Source Type: research

The clinical pharmacist role in patients with suspected allergy to beta-lactams: A systematic review
CONCLUSION: The pharmacist intervention in the evaluation of the patient with suspected allergy to beta-lactams is effective, safe and feasible to implement on daily clinical practice. The standardization of protocols to clarify the history of allergies and development of evaluation tools represent simple screenings to perform delabelling or refer to the Immunoallergology service, improving penicilins use and reducing the need for second line antibiotics. More studies are needed to standardize the desensitization tests made by pharmacists. However, despite these results, the involvement and leadership of the pharmacist in ...
Source: Farmacia Hospitalaria - September 11, 2023 Category: Drugs & Pharmacology Authors: Jesus Cotrina Luque Maria Jos é Rei Miriam Capoulas Cl áudia Santos Pedro Raimundo Source Type: research

Prevalence and time trends of symptoms of allergic rhinitis and rhinoconjunctivitis in Spanish children: Global Asthma Network (GAN) study
CONCLUSIONS: There has been a stabilisation of rhinitis, rhinoconjunctivitis and nasal allergy in schoolchildren that slows the previous upward trend of ISAAC; and a slight non-significant increase in rhinoconjunctivitis and nasal allergy in adolescents. The variability found in adolescents would require local research to be better understood.PMID:37695222 | DOI:10.15586/aei.v51i1.711
Source: Allergologia et Immunopathologia - September 11, 2023 Category: Allergy & Immunology Authors: Alberto Bercedo-Sanz Antonela Mart ínez-Torres Angel L ópez-Silvarrey Varela Francisco Javier Pellegrini Belinch ón Ines Aguinaga-Ontoso Carlos Gonz ález Díaz Luis Garc ía-Marcos Grupo Gan Spain Source Type: research

Outcomes and factors associated with tolerance in infants with non-IgE-mediated cow's milk allergy with gastrointestinal manifestations
CONCLUSIONS: In infants with non-IgE-mediated CMPA with gastrointestinal manifestations, the use of cow's milk-based formula, a history of other food allergies, and hematochezia and diarrhea upon initial presentation were associated factors for the later achievement of tolerance.PMID:37696495 | DOI:10.1016/j.jped.2023.08.003
Source: Jornal de Pediatria - September 11, 2023 Category: Pediatrics Authors: Pr íscila da Silva Pereira Vasconcelos Ana Laura Mendes Becker Andrade Natascha Silva Sandy Juliana Corr êa Campos Barreto Gabriela Souza Gomez Adriana Gut Lopes Riccetto Elizete Aparecida Lomazi Maria Ângela Bellomo-Brandão Source Type: research