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Total 17445 results found since Jan 2013.
Analysis of Positive Patch Test Allergens in Allergic Contact Dermatitis Patients with Atopic Dermatitis
CONCLUSION: Our study shows a decreased prevalence of contact sensitization in AD patients compared to non-AD patients. Clinicians should be aware of the risk of corticosteroid allergies in ACD patients with history of AD.PMID:37550231 | PMC:PMC10407336 | DOI:10.5021/ad.23.001
Source: Annals of Dermatology - August 7, 2023 Category: Dermatology Authors: Yoon Jin Choi Ji Yeon Byun You Won Choi Joo Young Roh Hae Young Choi Source Type: research
Drug Allergy in Older Adults: A Study from the United States Drug Allergy Registry
Older adults have an increased risk of adverse drug reactions and negative effects associated with alternative antibiotic use. Although number of antibiotic allergies reported increases with age, the characteristics and outcomes of older adults receiving drug allergy assessment are unknown.
Source: Annals of Allergy, Asthma and Immunology - August 7, 2023 Category: Allergy & Immunology Authors: John J.O. Accarino, Allison Ramsey, Upeka Samarakoon, Elizabeth Phillips, Alexei Gonzalez-Estrada, Iris M. Otani, Xiaoqing Fu, Aleena Banerji, Cosby A. Stone, David A. Khan, Kimberly G. Blumenthal, the USDAR Study Team Tags: Original Article Source Type: research
Maternal vitamin D –related metabolome and offspring risk of asthma outcomes
Vitamin D deficiency in childhood has been associated with various adverse health consequences as 25-hydroxyvitamin D (25(OH)D) possesses a range of immune regulatory properties with potential implications for proneness to respiratory infection, allergies, and asthma.1,2 Studies have further shown that 25(OH)D deficiency during pregnancy may affect fetal immune programming, consequently increasing the risk of asthma in early childhood.3,4 Therefore, we recently performed an intervention study in the Copenhagen Prospective Studies on Asthma in Childhood 2010 (COPSAC2010) cohort,5 which showed beneficial effects of high-dose...
Source: Journal of Allergy and Clinical Immunology - August 7, 2023 Category: Allergy & Immunology Authors: Min Kim, Nicklas Brustad, Mina Ali, G özde Gürdeniz, Morten Arendt, Augusto A. Litonjua, Craig E. Wheelock, Rachel S. Kelly, Yulu Chen, Nicole Prince, Feng Guo, Xiaobo Zhou, Jakob Stokholm, Klaus Bønnelykke, Scott T. Weiss, Hans Bisgaard, Jessica Lasky Source Type: research
Drug allergy in older adults
Older adults have an increased risk of adverse drug reactions and negative effects associated with alternative antibiotic use. Although the number of antibiotic allergies reported increases with age, the characteristics and outcomes of older adults receiving drug allergy assessment are unknown.
Source: Annals of Allergy, Asthma and Immunology - August 7, 2023 Category: Allergy & Immunology Authors: John J.O. Accarino, Allison Ramsey, Upeka Samarakoon, Elizabeth Phillips, Alexei Gonzalez-Estrada, Iris M. Otani, Xiaoqing Fu, Aleena Banerji, Cosby A. Stone, David A. Khan, Kimberly G. Blumenthal, the United States Drug Allergy Registry Study Team Source Type: research
Anti-tumor activity of trimethoprim-sulfamethoxazole against melanoma skin cancer through triggering allergic reaction and promoting immunity
This study examined the potential roles of TMP-SMX in melanoma skin cancer using an immunodeficient mouse model. TMP-SMX significantly improved the survival rate and reduced the tumor weight and growth and vascular endothelial growth factor levels in melanoma skin cancer of immunodeficient mice. In the forced swimming test, TMP-SMX significantly reduced immobility time compared to the melanoma skin cancer of immunodeficient mice, indicating improved immunity. TMP-SMX significantly increased infiltration of mast cells and release of allergy-related mediators (IgE, histamine, interleukin (IL)-4, IL-5, IL-13, and IL-33) and i...
Source: International Immunopharmacology - August 3, 2023 Category: Allergy & Immunology Authors: Hee-Yun Kim Ho-Geun Kang Hyung-Min Kim Hyun-Ja Jeong Source Type: research
Doctors have long considered the thymus expendable. But could removing it be fatal?
The thymus, a butterfly-shaped organ that sits between our collarbones, has never seemed like a particularly useful appendage—at least in adults. During early childhood, it provides a place for T cells (the T stands for thymus) to mature into immune cells that attack invaders. But during adolescence the organ begins to shrink and mostly stops producing these cells. By adulthood, it’s assumed to be so useless that cardiac surgeons will occasionally remove it just to get easier access to the heart.
But researchers have recently started to question that assumption, and a study published today in
The New England Jo...
Source: ScienceNOW - August 2, 2023 Category: Science Source Type: news
HIV researcher will head NIH ’s infectious disease institute
The infectious disease institute at the U.S. National Institutes of Health (NIH) will soon have its first new chief in nearly 4 decades. Jeanne Marrazzo, an expert on sexually transmitted infections, will become director of the National Institute of Allergy and Infectious Diseases (NIAID) in the fall. She will succeed Anthony Fauci, who
stepped down
in December 2022 after 38 years at NIAID’s helm.
Marrazzo, 61, currently directs the Division of Infectious Diseases at the University of Alabama at Birmingham (UAB). A physician and epidemiologist, she has expertise in HIV prevention, vaginal infections, horm...
Source: ScienceNOW - August 2, 2023 Category: Science Source Type: news
University of Alabama HIV researcher will head NIH ’s infectious disease institute
The infectious disease institute at the U.S. National Institutes of Health (NIH) will soon have its first new chief in nearly 4 decades. Jeanne Marrazzo, an expert on sexually transmitted infections, will become director of the National Institute of Allergy and Infectious Diseases (NIAID) in the fall. She will succeed Anthony Fauci, who
stepped down
in December 2022 after 38 years at NIAID’s helm.
Marrazzo, 61, currently directs the Division of Infectious Diseases at the University of Alabama at Birmingham (UAB). A physician and epidemiologist, she has expertise in HIV prevention, vaginal infections, horm...
Source: ScienceNOW - August 2, 2023 Category: Science Source Type: news
An outlook on the target-based molecular mechanism of phytoconstituents as immunomodulators
Phytother Res. 2023 Aug 1. doi: 10.1002/ptr.7969. Online ahead of print.ABSTRACTThe immune system is one of the essential defense mechanisms. Immune system inadequacy increases the risk of infections and cancer diseases, whereas over-activation of the immune system causes allergies or autoimmune disorders. Immunomodulators have been used in the treatment of immune-related diseases. There is growing interest in using herbal medicines as multicomponent agents to modulate the complex immune system in immune-related diseases. Many therapeutic phytochemicals showed immunomodulatory effects by various mechanisms. This mechanism ...
Source: Cell Research - August 2, 2023 Category: Cytology Authors: Gazala Noor None Badruddeen Juber Akhtar Bhuwanendra Singh Mohammad Ahmad Mohammad Irfan Khan Source Type: research
UCSF researchers' startup aims to stop allergies — starting with babies' guts
The company's backers have included Khosla Ventures and Salesforce.com founder Marc Benioff.
Source: bizjournals.com Health Care:Pharmaceuticals headlines - August 1, 2023 Category: Pharmaceuticals Authors: Ron Leuty Source Type: news
Penicillin Allergy Impact and Management
There is international evidence that penicillin allergies are associated with inferior prescribing and patient outcomes. A host of tools now exist from assessment (risk assessment tools, clinical decision rules) to delabeling (the removal of a beta-lactam allergy via testing or medical reconciliation) to reduce the impact of these “labels” in the hospital and community setting, as a primary antimicrobial stewardship intervention.
Source: Infectious Diseases Clinics of North America - August 1, 2023 Category: Infectious Diseases Authors: Rebekah H. Wrenn, Jason A. Trubiano Source Type: research
Allergies Come Clean: The Role of Detergents in Epithelial Barrier Dysfunction
The objective of this review is to examine the role of detergents as a potential risk factor for developing allergic disease.Recent FindingsHerein, we identify key sources of human detergent exposure. We summarize the evidence suggesting a possible role for detergents and related chemicals in initiating epithelial barrier dysfunction and allergic inflammation. We primarily focus on experimental models of atopic dermatitis, asthma, and eosinophilic esophagitis, which show compelling associations between allergic disease and detergent exposure. Mechanistic studies suggest that detergents disrupt epithelial barrier integrity ...
Source: Current Allergy and Asthma Reports - August 1, 2023 Category: Allergy & Immunology Source Type: research
