Subclassification Can Tailor Surveillance for Pancreatic Adenocarcinoma
WEDNESDAY, April 17, 2024 -- Subclassification of individuals at high risk for pancreatic adenocarcinoma (PC) can enable the development of surveillance approaches better tailored to risk, according to a study published online April 16 in the... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 17, 2024 Category: Pharmaceuticals Source Type: news

FAPI-PET shows promise in patients with lung cancer
FAPI-PET imaging could emerge as a new tool for assessing patients with single pulmonary tumors, especially in those with negative results on other scans, according to a study published April 11 in the Journal of Nuclear Medicine. A group at University Hospital Heidelberg in Germany assessed the approach in 19 patients referred by their treating physicians because of inconclusive lung cancer findings on CT and F-18 FDG-PET. FAPI-PET either confirmed or ruled out the disease in all cases, the group found. “Our results suggest that supplemental Ga-68 FAPI-46 PET may improve the noninvasive assessment of primary pulmonary...
Source: AuntMinnie.com Headlines - April 15, 2024 Category: Radiology Authors: Will Morton Tags: Molecular Imaging Source Type: news

AI model predicts invasiveness of lung cancer on CT scans
Radiologists in Beijing, China, have developed a joint deep learning and radiomics AI model that can flag how invasive tumors may be in patients with lung cancer, according to a study published April 9 in Radiology. The approach could ultimately help clinicians determine which patients with suspected disease are candidates for surgery, noted led authors Zhengsong Pan and Ge Hu, PhD, of Peking Union Medical College Hospital. “These models could assist in the preoperative care of patients with lung adenocarcinoma,” the group wrote. Lung adenocarcinoma is the most common primary lung cancer seen in the U.S. Tumors mani...
Source: AuntMinnie.com Headlines - April 9, 2024 Category: Radiology Authors: Will Morton Tags: CT Artificial Intelligence Thoracic Imaging Source Type: news

AACR: Exosome-Based miRNA Assay Can Detect Pancreatic Cancer
MONDAY, April 8, 2024 -- An exosome-based liquid biopsy assay can distinguish patients with pancreatic ductal adenocarcinoma (PDAC) from healthy donors (HDs), according to a study presented at the annual meeting of the American Association for... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 8, 2024 Category: Pharmaceuticals Source Type: news

AACR: Cadonilimab Plus Chemo Beneficial for Gastric Adenocarcinoma
MONDAY, April 8, 2024 -- For patients with gastric/gastroesophageal junction (G/GEJ) adenocarcinoma, cadonilimab plus chemotherapy is associated with improved overall survival and progression-free survival, according to a study presented at the... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 8, 2024 Category: Pharmaceuticals Source Type: news

Chemotherapy/ICI Combos Falter as Second-Line Treatment for Gastric Cancer
(MedPage Today) -- Combining chemotherapy with one or two immune checkpoint inhibitors (ICIs) as second-line treatment for advanced gastric or gastroesophageal junction (GEJ) adenocarcinoma failed to improve progression-free survival (PFS) at 4... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - April 5, 2024 Category: Gastroenterology Source Type: news

Certain Pesticides Linked With Risk for Pancreatic Cancer Certain Pesticides Linked With Risk for Pancreatic Cancer
The incidence of pancreatic adenocarcinoma has been increasing steadily for more than 30 years.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - April 3, 2024 Category: Cancer & Oncology Tags: Hematology-Oncology Source Type: news

Training technique in AI helps preserve patient privacy
The privacy of patient data in AI models trained on chest x-rays can be guaranteed – importantly, without significantly reducing the accuracy of models on large “real-world” data sets, according to a study published March 14 in Communications Medicine. A team in Germany used an approach called “differential privacy” when training large-scale AI models and then evaluated its effects on model performance. They found high accuracy was attainable, despite the stringent privacy guarantees, noted lead authors and PhD students Soroosh Tayebi Arasteh, of University Hospital RWTH Aachen, and Alexander Ziller, of the Tech...
Source: AuntMinnie.com Headlines - March 18, 2024 Category: Radiology Authors: Will Morton Tags: CT Digital X-Ray Source Type: news

Ipsen ’s Onivyde Regimen, a Potential New Standard-of-Care First-Line Therapy in Metastatic Pancreatic Adenocarcinoma, Approved by FDA
PARIS, FRANCE, 13 February 2024– Ipsen (Euronext: IPN; ADR: IPSEY) announced today that the U.S. Food and Drug Administration (FDA) has approved the supplemental new drug application for Onivyde (irinotecan liposome injection) plus... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - February 13, 2024 Category: Drugs & Pharmacology Source Type: news

FDA approves irinotecan liposome for first-line treatment of metastatic pancreatic adenocarcinoma
On February 13, 2024, the Food and Drug Administration approved irinotecan liposome (Onivyde, Ipsen Biopharmaceuticals, Inc.) with oxaliplatin, fluorouracil, and leucovorin, for the first-line treatment of metastatic pancreatic adenocarcinoma. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 13, 2024 Category: Drugs & Pharmacology Authors: FDA Source Type: news

New First-Line Option for Pancreatic Cancer Approved
(MedPage Today) -- The FDA approved irinotecan liposome (Onivyde) in combination with oxaliplatin, leucovorin, and fluorouracil (NALIRIFOX) for the first-line treatment of metastatic pancreatic adenocarcinoma, the agency announced on Tuesday.... (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - February 13, 2024 Category: American Health Source Type: news

Fruquintinib + Paclitaxel Aids Advanced Gastric/Gastroesophageal Junction Cancer
MONDAY, Feb. 12, 2024 -- For patients with advanced gastric or gastroesophageal junction (G/GEJ) adenocarcinoma who experienced disease progression on first-line chemotherapy, fruquintinib (F) plus paclitaxel (PTX) improves progression free survival... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 12, 2024 Category: Pharmaceuticals Source Type: news

Sequential Therapy Boosts Survival in Metastatic Pancreatic Cancer
(MedPage Today) -- For patients with metastatic pancreatic ductal adenocarcinoma (PDAC), sequential treatment with nab-paclitaxel (Abraxane) plus gemcitabine followed by modified oxaliplatin, leucovorin, and fluorouracil (mFOLFOX) led to improved... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - January 31, 2024 Category: Gastroenterology Source Type: news

Treatment Sequence May Impact Pancreatic Cancer Survival Treatment Sequence May Impact Pancreatic Cancer Survival
The sequence of systemic therapies for advanced pancreatic ductal adenocarcinoma can affect overall patient survival, a new analysis suggests.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - January 29, 2024 Category: Cancer & Oncology Tags: Hematology-Oncology Source Type: news

FAPI-PET outperforms FDG-PET in diagnosing pancreatic cancer
F-18 FAPI-PET/CT is superior to F-18 FDG-PET/CT for diagnosing and staging patients with pancreatic cancer, according to a study published January 4 in the Journal of Nuclear Medicine. In a clinical trial, F-18 FAPI-04 radiotracer performed better than F-18 FDG in identifying primary tumors, lymph node metastasis, and distant metastases in patients with pancreatic ductal adenocarcinoma (PDAC). The findings suggest that F-18 FAPI-04 PET/CT offers a new method for identifying malignancies in these patients, according to first author Xiang Li, PhD, of Zhejiang University in Hangzhou, China, and colleagues. “In the future,...
Source: AuntMinnie.com Headlines - January 5, 2024 Category: Radiology Authors: Will Morton Tags: Subspecialties Molecular Imaging Radiation Oncology/Therapy Nuclear Radiology Source Type: news