Preoperative and postoperative blood testosterone levels in patients with acromegaly: a prospective study
ConclusionThe invasiveness of tumor and levels of blood prolactin are independent factors for LTLs before surgery, whereas GH and IGF-1 levels are not. Most male patients can recover from LTL after tumor restriction surgery: those who recover from acromegaly have a better chance of recovering from LTL. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - October 11, 2023 Category: Endocrinology Source Type: research
Debulking surgery for macrodystrophia lipomatosa of the lesser toe: a rare case report
We report a case of a woman in her late 60s who presented with abnormal enlargement of the right second toe. By debulking the pathological tissue while preserving the shape of the toe as much as possible without amputation of the entire phalanx, debulking surgery not only helps walking, but also allows wearing shoes of the same size on both feet and achieves cosmetic satisfaction for patients. The functional and cosmetic improvement obtained through debulking surgery in this case resulted in no recurrence of disease 5 years postoperatively and provided a desirable alternative to amputation. Therefore, through this case, we...
Source: Cell Research - October 9, 2023 Category: Cytology Authors: Sung Hyun Lee Yang Hun Jo Source Type: research
Preference of acromegaly patients for treatment attributes in Spain
ConclusionsQoL greatly influences patient treatment preference. Since acromegaly patients are informed and aware of their disease, treatment choices should always be shared with patients. (Source: Endocrine)
Source: Endocrine - October 5, 2023 Category: Endocrinology Source Type: research
Incidence and risk factors of cancers in acromegaly: a Chinese single-center retrospective study
ConclusionThe risk of malignancies, especially thyroid cancer, was increased in patients with acromegaly in our center. More cancer screening should be considered when managing acromegaly, especially in patients with higher posttreatment GH and IGF-1. (Source: Endocrine)
Source: Endocrine - October 5, 2023 Category: Endocrinology Source Type: research
Preference of acromegaly patients for treatment attributes in Spain
ConclusionsQoL greatly influences patient treatment preference. Since acromegaly patients are informed and aware of their disease, treatment choices should always be shared with patients. (Source: Endocrine)
Source: Endocrine - October 1, 2023 Category: Endocrinology Source Type: research
Incidence and risk factors of cancers in acromegaly: a Chinese single-center retrospective study
ConclusionThe risk of malignancies, especially thyroid cancer, was increased in patients with acromegaly in our center. More cancer screening should be considered when managing acromegaly, especially in patients with higher posttreatment GH and IGF-1. (Source: Endocrine)
Source: Endocrine - October 1, 2023 Category: Endocrinology Source Type: research
Changing presentation of acromegaly in half a century: a single-center experience
ConclusionThere may be a trend for earlier detection of patients with acromegaly. (Source: Pituitary)
Source: Pituitary - September 28, 2023 Category: Endocrinology Source Type: research
Practical therapeutic approach in the management of diabetes mellitus secondary to Cushing ’s syndrome, acromegaly and neuroendocrine tumours
Cushing’s syndrome, acromegaly and neuroendocrine disorders are characterized by an excess of counterregulatory hormones, able to induce insulin resistance and glucose metabolism disorders at variable degrees and requiring immediate treatment, until patients are ready to undergo surgery. This review focuses on the management of diabetes mellitus in endocrine disorders related to an excess of counterregulatory hormones. Currently, the landscape of approved agents for treatment of diabetes is dynamic and is mainly patient-centred and not glycaemia-centred. In addition, personalized medicine is more and more required to pro...
Source: Frontiers in Endocrinology - September 28, 2023 Category: Endocrinology Source Type: research
Simultaneous rectal neuroendocrine tumors and pituitary adenoma: A case report and review of literature
CONCLUSION: 18F-ALF-NOTATE PET/CT and MRI with pathological analysis can effectively diagnose rare cases of pituitary adenomas complicated with rectal NET.PMID:37753367 | PMC:PMC10518740 | DOI:10.3748/wjg.v29.i34.5082 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - September 27, 2023 Category: Gastroenterology Authors: Jing-Yi Li Jie Chen Jun Liu Su-Zhen Zhang Source Type: research
Simultaneous rectal neuroendocrine tumors and pituitary adenoma: A case report and review of literature
CONCLUSION: 18F-ALF-NOTATE PET/CT and MRI with pathological analysis can effectively diagnose rare cases of pituitary adenomas complicated with rectal NET.PMID:37753367 | PMC:PMC10518740 | DOI:10.3748/wjg.v29.i34.5082 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - September 27, 2023 Category: Gastroenterology Authors: Jing-Yi Li Jie Chen Jun Liu Su-Zhen Zhang Source Type: research
New Treatments for Acromegaly in Development
J Clin Endocrinol Metab. 2023 Sep 27:dgad568. doi: 10.1210/clinem/dgad568. Online ahead of print.ABSTRACTAcromegaly treatment has greatly evolved in recent decades, but there are still patients whose acromegaly is not controlled with currently available treatments, and there is a need to improve the treatment burden. Fortunately, there are new treatments under development that may increase treatment efficacy and convenience.PMID:37757837 | DOI:10.1210/clinem/dgad568 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - September 27, 2023 Category: Endocrinology Authors: M ônica R Gadelha Ana Carolina Gadelha Leandro Kasuki Source Type: research
Simultaneous rectal neuroendocrine tumors and pituitary adenoma: A case report and review of literature
CONCLUSION: 18F-ALF-NOTATE PET/CT and MRI with pathological analysis can effectively diagnose rare cases of pituitary adenomas complicated with rectal NET.PMID:37753367 | PMC:PMC10518740 | DOI:10.3748/wjg.v29.i34.5082 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - September 27, 2023 Category: Gastroenterology Authors: Jing-Yi Li Jie Chen Jun Liu Su-Zhen Zhang Source Type: research
Simultaneous rectal neuroendocrine tumors and pituitary adenoma: A case report and review of literature
CONCLUSION: 18F-ALF-NOTATE PET/CT and MRI with pathological analysis can effectively diagnose rare cases of pituitary adenomas complicated with rectal NET.PMID:37753367 | PMC:PMC10518740 | DOI:10.3748/wjg.v29.i34.5082 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - September 27, 2023 Category: Gastroenterology Authors: Jing-Yi Li Jie Chen Jun Liu Su-Zhen Zhang Source Type: research
Simultaneous rectal neuroendocrine tumors and pituitary adenoma: A case report and review of literature
CONCLUSION: 18F-ALF-NOTATE PET/CT and MRI with pathological analysis can effectively diagnose rare cases of pituitary adenomas complicated with rectal NET.PMID:37753367 | PMC:PMC10518740 | DOI:10.3748/wjg.v29.i34.5082 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - September 27, 2023 Category: Gastroenterology Authors: Jing-Yi Li Jie Chen Jun Liu Su-Zhen Zhang Source Type: research
Simultaneous rectal neuroendocrine tumors and pituitary adenoma: A case report and review of literature
CONCLUSION: 18F-ALF-NOTATE PET/CT and MRI with pathological analysis can effectively diagnose rare cases of pituitary adenomas complicated with rectal NET.PMID:37753367 | PMC:PMC10518740 | DOI:10.3748/wjg.v29.i34.5082 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - September 27, 2023 Category: Gastroenterology Authors: Jing-Yi Li Jie Chen Jun Liu Su-Zhen Zhang Source Type: research
