Log in to search using one of your social media accounts:

This page shows you the latest news items in this category.

Writer whose jaw expanded because of rare condition reveals how he could die at any minute
Up to 8,300 people in the UK, including Mike Scalise, have acromegaly - where the body produces too much growth hormone - but it often isn't diagnosed until patients are in their 40s. (Source: the Mail online | Health)
Source: the Mail online | Health - January 9, 2017 Category: Consumer Health News Source Type: news

Writer, 38, whose jaw expanded in size because of a rare condition made famous by a James Bond villain reveals how he could die at any minute from stress
Up to 8,300 people in the UK, including Mike Scalise, have acromegaly - where the body produces too much growth hormone - but it often isn't diagnosed until patients are in their 40s. (Source: the Mail online | Health)
Source: the Mail online | Health - January 9, 2017 Category: Consumer Health News Source Type: news

What are Potential Health Problems Associated with Polycystic Ovary Syndrome?
DiscussionPolycystic ovary syndrome (PCOS) affects 6-8% of reproductive-age women making it the most common endocrinopathy in this age group. There is no consensus on the specific diagnostic criteria for PCOS in adolescents as many of the characteristics overlap with normal adolescent physiology. However, patients should have evidence of hyperandrogenism, oligo- or amenorrhea, and potentially polycystic ovaries. PCOS has a genetic component although a specific gene has not been identified. Incidence of PCOS is 20-40% for a woman with a family history. Hyperandrogenism Androgen levels change during puberty therefore actual ...
Source: PediatricEducation.org - December 5, 2016 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

This Teen Is Almost 8 Feet Tall -- And Still Growing
function onPlayerReadyVidible(e){'undefined'!=typeof HPTrack&&HPTrack.Vid.Vidible_track(e)}!function(e,i){if(e.vdb_Player){if('object'==typeof commercial_video){var a='',o='m.fwsitesection='+commercial_video.site_and_category;if(a+=o,commercial_video['package']){var c='&m.fwkeyvalues=sponsorship%3D'+commercial_video['package'];a+=c}e.setAttribute('vdb_params',a)}i(e.vdb_Player)}else{var t=arguments.callee;setTimeout(function(){t(e,i)},0)}}(document.getElementById('vidible_1'),onPlayerReadyVidible); At 7 feet 8 inches, Broc Brown definitely sticks out in a crowd, and he’s only going to get bigger. Brown’s fam...
Source: Healthy Living - The Huffington Post - September 23, 2016 Category: Consumer Health News Source Type: news

What Causes Hyperphosphatemia?
Discussion Constipation is a common problem in general pediatrics and its causes are numerous. It can cause acute and recurrent abdominal pain and is a cause of abdominal distention. Patients who are young, whose presentations are other than routine or who had complications should be invested for underlying causes of their constipation. This patient had undergone some evaluations in the past for constipation but because of the presentation of sepsis a more rigorous evaluation was undertaken. The differential diagnoses of the following can be found here: constipation, acute abdominal pain, recurrent abdominal pain, and abdo...
Source: PediatricEducation.org - September 12, 2016 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Acromegaly FAQs
(Source: eMedicineHealth.com)
Source: eMedicineHealth.com - July 15, 2016 Category: Journals (General) Source Type: news

Understanding Acromegaly Medications
Acromegaly Medications (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - July 15, 2016 Category: Journals (General) Source Type: news

Camurus concludes Phase II trial of CAM2029 to treat NETs
Swedish-based pharmaceutical company Camurus has concluded the Phase II study of CAM2029 to treat acromegaly or neuroendocrine tumours (NETs). (Source: Drug Development Technology)
Source: Drug Development Technology - July 14, 2016 Category: Pharmaceuticals Source Type: news

Indian man with enormous 20kg arm is forced to leave his home
Bablu, who was forced to flee to Mumbai, suffers from local gigantism, which is the result of an over-productive growth hormone. His condition means he even struggles to hold a cup of water. (Source: the Mail online | Health)
Source: the Mail online | Health - May 26, 2016 Category: Consumer Health News Source Type: news

Radiosurgery in Patients With Acromegaly or Cushing DiseaseRadiosurgery in Patients With Acromegaly or Cushing Disease
A new study reports on the incidence of hypopituitarism after gamma knife radiosurgery in patients with acromegaly or Cushing's disease. Clinical Endocrinology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 10, 2016 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

FDA rejects Chiasma's drug to treat growth disorder
The U.S. Food and Drug Administration has rejected Chiasma Inc's experimental drug to treat adults with acromegaly, the company said on Friday. Reuters (Source: Society for Endocrinology)
Source: Society for Endocrinology - April 21, 2016 Category: Endocrinology Source Type: news

ACROSCORE: A New and Simple Tool for Diagnosing AcromegalyACROSCORE: A New and Simple Tool for Diagnosing Acromegaly
A novel scoring tool has been developed that may play an important role in the diagnosis of this rare disease. Clinical Endocrinology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 19, 2016 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Your Dentist Is More Important to Your General Health Than You May Realize
Most people view their twice-yearly visits to the dentist as little more than a cleaning and a check-up. But in reality, those visits are much more important than you probably realize. That's because your dentist is looking inside your mouth for a lot more than cavities. Plenty of medical conditions -- including some alarming ones! -- manifest in the mouth, which is the part of your body your dentist knows the most about. In fact, it's possible that your dentist is able to alert you of a potentially serious condition long before you even think about going to a primary care doctor. Here's a list of some of the medical cond...
Source: Healthy Living - The Huffington Post - March 29, 2016 Category: Consumer Health News Source Type: news

Greeks Gone West: The Geneticist Helping To Treat 'Gigantism'
Constantine A. Stratakis - Greeks Gone West by HuffPost_Greece In the third episode of HuffPost Greece's video series 'Greeks Gone West,' we introduce Constantine A. Stratakis, M.D. D.Sc., a tenured investigator in the NICHD, who has been the head of the Section on Genetics and Endocrinology (SEGEN) since its inception in 1999. His work is focused on treating the rare condition of 'gigantism.' The research began with a family who came to the the U.S. National Institutes of Health for treatment for gigantism in the mid-1990s. In that family, the mother and two of her sons all had the condi...
Source: Science - The Huffington Post - October 16, 2015 Category: Science Source Type: news

How Big Could a World Record Pumpkin Get?
This article originally appeared on Inverse. By Ben Guarino Thanks to the efforts of Illinois farmer Gene McMullen, the North American record for the heaviest pumpkin now sits at 2,145 pounds. McMullen's Cucurbita Maxima Brobdingnag is the second greatest pumpkin the world has ever known, trailing only Beni Meier of Switzerland's monster fruit, which tipped the scales at 2,378 pounds in 2014. The most remarkable thing about these overachieving gourds is that their size is not singular: The weight of the massive pumpkin growth has been linear over the past few decades according to an analysis by University of Wisconsin-Mad...
Source: Science - The Huffington Post - October 2, 2015 Category: Science Source Type: news

Indian boy with giant hands from local gigantism gets life changing operation
Mohammad Kaleem, eight, from Jharkhand State, eastern India, was born with a form of giantism which has seen his hands and arms grow until they weighed a colossal two stone between them. (Source: the Mail online | Health)
Source: the Mail online | Health - August 10, 2015 Category: Consumer Health News Source Type: news

Why Were Dinosaurs So Big?
Why were dinosaurs so big?: originally appeared on Quora: The best answer to any question. Ask a question, get a great answer. Learn from experts and access insider knowledge. You can follow Quora on Twitter, Facebook, and Google+. Answer by Marc Srour, Invertebrate Paleontologist Image by MathKnight There is actually no uncontroversial explanation for the as-of-yet unparalleled size of dinosaurs. If you look at the distribution of large sizes in dinosaurs, one distinction becomes clear: the only dinos that were small (less than 1m) were carnivorous theropods. Except for the 70 cm Fruitadens Haagarorum, no herbivorous or...
Source: Science - The Huffington Post - July 7, 2015 Category: Science Source Type: news

Research Goal: 'No More Giants'Research Goal: 'No More Giants'
A gene linked to 'gigantism' may hold the key to identifying and treating babies who otherwise would grow extremely tall and have shortened life spans. Medscape Diabetes & Endocrinology (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - April 25, 2015 Category: Endocrinology Tags: Diabetes & Endocrinology Commentary Source Type: news

Funding for nurses wishing to attend ECE 2015
An educational programme for endocrine nurses has been arranged at ECE 2015 in Dublin. It includes a half-day pre-congress course on Acromegaly on Saturday 16 May and 3 dedicated nurse sessions as part of the ECE Programme on 17 and 18 May. There will also be opportunities for networking during catering breaks and poster presentations. An unrestricted educational grant which can fund up to 55 nurses with a €500 travel grant to attend the Acromegaly course and ECE meeting has been provided by pharmaceutical sponsors; these will be awarded on a first-come-first-serve basis. Please visit the&n...
Source: Society for Endocrinology - March 26, 2015 Category: Endocrinology Source Type: news

Chiasma Announces Completion of $70 Million Series E Financing
NEWTON, Mass. and JERUSALEM, Feb. 27, 2015 -- (Healthcare Sales & Marketing Network) -- Chiasma, Inc., a U.S. privately-held biopharma company developing octreotide capsules, its lead product for the orphan condition acromegaly, today announced the closin... Biopharmaceuticals, Venture CapitalChiasma, octreotide capsules, acromegaly (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - February 27, 2015 Category: Pharmaceuticals Source Type: news

Acromegaly Responds to Oral Drug in Trial (CME/CE)
(MedPage Today) -- Tradeoff between convenience and lower response rate versus injectable treatments. (Source: MedPage Today Endocrinology)
Source: MedPage Today Endocrinology - February 10, 2015 Category: Endocrinology Source Type: news

New Indications for Somatostatin Analogs
(MedPage Today) -- FDA okayed pasireotide for acromegaly and lanreotide for gastroenteropancreatic neuroendocrine tumors. (Source: MedPage Today Endocrinology)
Source: MedPage Today Endocrinology - December 19, 2014 Category: Endocrinology Source Type: news

FDA Okays Pasireotide (Signifor LAR) for AcromegalyFDA Okays Pasireotide (Signifor LAR) for Acromegaly
The long-acting somatostatin analog pasireotide has been approved for the additional indication of treatment of acromegaly in the US, for patients who don't respond well to surgery or first-line agents. FDA Approvals (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - December 17, 2014 Category: Endocrinology Tags: Diabetes & Endocrinology News Alert Source Type: news

Novartis receives FDA approval for Signifor LAR to treat acromegaly
Swiss drugmaker Novartis has received approval from US Food and Drug Administration (FDA) for its Signifor long-acting release LAR (pasireotide) for injectable suspension and intramuscular use to treat patients with acromegaly. (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - December 17, 2014 Category: Pharmaceuticals Source Type: news

Gene Discovery in Giants Could Shed Light on Human GrowthGene Discovery in Giants Could Shed Light on Human Growth
A duplication in a gene on the X chromosome is associated with an early-onset form of gigantism; the discovery is likely to shed light on how growth hormone is regulated, the researchers say. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 9, 2014 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Genetic basis for gigantism identified
Researchers at the National Institutes of Health have found a duplication of a short stretch of the X chromosome in some people with a rare disorder that causes excessive childhood growth; their study was published this week in The New England Journal of Medicine. Medical Xpress (Source: Society for Endocrinology)
Source: Society for Endocrinology - December 9, 2014 Category: Endocrinology Source Type: news

This Week: CDC Says Severe Flu Season Possible
(MedPage Today) -- The CDC warns about the coming flu season, and researchers report on a possible cause of gigantism in children. (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - December 5, 2014 Category: American Health Source Type: news

Duplication of gene on X chromosome causes gigantism
Brooks HaysBETHESDA, Md., Dec. 4 (UPI) -- Researchers now believe gene duplication in a specific chromosome region, key in growth regulation, is responsible for the rare disorder known as gigantism. (Source: Health News - UPI.com)
Source: Health News - UPI.com - December 4, 2014 Category: Consumer Health News Source Type: news

Duplication Error May Make Giants
(MedPage Today) -- Novel mutation may underlie some cases of gigantism. (Source: MedPage Today Pediatrics)
Source: MedPage Today Pediatrics - December 4, 2014 Category: Pediatrics Source Type: news

NIH researchers link chromosome region to gigantism
Duplication of gene on X chromosome appears to cause excessive growth (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - December 4, 2014 Category: American Health Source Type: news

Scientists May Have Spotted Genetic Cause of 'Gigantism'
Title: Scientists May Have Spotted Genetic Cause of 'Gigantism'Category: Health NewsCreated: 12/3/2014 12:00:00 AMLast Editorial Review: 12/4/2014 12:00:00 AM (Source: MedicineNet Kids Health General)
Source: MedicineNet Kids Health General - December 4, 2014 Category: Pediatrics Source Type: news

Novartis received EU approval for drug that treats rare hormonal disorder
Novartis International has announced that it has received approval from the European Commission for its drug called Signifor to treat the rare hormonal disorder acromegaly. HNGN (Source: Society for Endocrinology)
Source: Society for Endocrinology - November 25, 2014 Category: Endocrinology Source Type: news

European Commission grants approval for Novartis's Signifor to treat acromegaly
Swiss drug-maker Novartis has received approval from European Commission for its Signifor (pasireotide) intramuscular injection to treat adult patients suffering from acromegaly. (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - November 25, 2014 Category: Pharmaceuticals Source Type: news

New guidelines for acromegaly include advice on pregnancy
The European Society of Endocrinology and the Endocrine Society have cosponsored a clinical practice guideline for the diagnosis and treatment of acromegaly. This is now available online in the Journal of Clinical Endocrinology & Metabolism. JCEM (Source: Society for Endocrinology)
Source: Society for Endocrinology - November 11, 2014 Category: Endocrinology Source Type: news

New Guidelines for Acromegaly Include Advice on PregnancyNew Guidelines for Acromegaly Include Advice on Pregnancy
The US Endocrine Society issues first-ever guidance on management of acromegaly, cosponsored by the European Society of Endocrinology. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 10, 2014 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Acromegaly diagnosis and treatment guideline issued by The Endocrine Society
A new clinical practice guideline developed by The Endocrine Society and published in the Journal of Clinical Endocrinology & Metabolism addresses evaluation and management of acromegaly. Healio (Source: Society for Endocrinology)
Source: Society for Endocrinology - November 6, 2014 Category: Endocrinology Source Type: news

Experts recommend tumour removal as first-line treatment for acromegaly
The Endocrine Society has today issued a Clinical Practice Guideline for the diagnosis and treatment of acromegaly, recommending that surgery to remove tumours from the pituitary gland should be the primary treatment for most patients. EurekAlert (Source: Society for Endocrinology)
Source: Society for Endocrinology - October 31, 2014 Category: Endocrinology Source Type: news

Experts recommend tumor removal as first-line treatment for acromegaly
(The Endocrine Society) The Endocrine Society today issued a Clinical Practice Guideline for the diagnosis and treatment of acromegaly, a rare condition caused by excess growth hormone in the blood. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 30, 2014 Category: Global & Universal Source Type: news

Teenager Keiran Halliday grows 8 inches in a YEAR after brain tumour
Keiran Halliday, 19, from Bridgend, South Wales, has shot up eight inches in the last year after he was diagnosed with acromegaly, where the body produces too much growth hormone. (Source: the Mail online | Health)
Source: the Mail online | Health - October 15, 2014 Category: Consumer Health News Source Type: news

Ghrelin paralleled adiposity increase after acromegaly surgery
The rise in total ghrelin found to accompany some remaining cardiovascular risk markers and adiposity increase in patients with acromegaly remission after surgery could be interrelated, according to research published in The Journal of Clinical Endocrinology & Metabolism.  Healio (Source: Society for Endocrinology)
Source: Society for Endocrinology - September 15, 2014 Category: Endocrinology Source Type: news

Understanding Acromegaly Medications
Acromegaly Medications (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - September 15, 2014 Category: Journals (General) Source Type: news

Acromegaly FAQs
(Source: eMedicineHealth.com)
Source: eMedicineHealth.com - August 28, 2014 Category: Journals (General) Source Type: news

Hustle and bustle at ICE/ENDO 2014
I arrived at McCormick Place to find all the usual hustle and bustle associated with ENDO. I queued, picked up my chic (!) backpack and rushed off to hang my poster. I also had a chance to take a peak at the history of endocrinology timeline as the Endocrine Society approaches it's centenary.  ENDO2014 was officially kicked off yesterday by Robert Lefkowitz who gave us an insightful tour through his lifetime's research on seven transmembrane receptors. His more recent discoveries on B-arrestins were fascinating. I bumped into Sam Mirczuk, Chair of the YE committee in this session :) John Newell-P...
Source: Society for Endocrinology - July 2, 2014 Category: Endocrinology Source Type: news

'I'm the real life Jaws': Student, 36, has condition which means his jaw bone won't stop growing
Richard Moore, from Wigan, has acromegaly - meaning some of his bones continue to increase in size after the skeleton and other organs have finished growing. (Source: the Mail online | Health)
Source: the Mail online | Health - June 20, 2014 Category: Consumer Health News Source Type: news

2014 ASPIRE Young Investigator Research Awards in Endocrinology
The mission of the 2014 ASPIRE Young Investigator Research Awards in Endocrinology is to advance the medical knowledge of the fundamental mechanisms of disease, mechanisms of action of current and potential future treatments, and to improve the care of patients with endocrine disorders. Funding will be provided to research proposals that seek to explore basic, translational, or clinical research in the area of endocrine disease in adults and children: Clinical and Translational Research in the GH and IGF-I Axis Morbidity and Mortality in Patients with Acromegaly Novel measures of growth hormone treatment benefits S...
Source: Society for Endocrinology - May 21, 2014 Category: Endocrinology Source Type: news

Pasireotide LAR for Acromegaly but Hyperglycemia a DrawbackPasireotide LAR for Acromegaly but Hyperglycemia a Drawback
Pasireotide LAR improves response in acromegaly patients poorly controlled on first-generation somatostatins, but hyperglycemia remains an issue as the agent awaits regulatory approval for this indication. Medscape Medical News (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - May 16, 2014 Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news

New Funding for Clinical Endocrinology Quality Improvement Projects available from the Clinical Endocrinology Trust
The Clinical Endocrinology Trust has long supported Endocrine Audit projects within the UK.  Recent examples include the UK Acromegaly Database, the CaHASE audit of adults with CAH, and a BTA study of teenage iodine status across the UK. The Trustees now invite further applications from Societies or Endocrine Centres within the UK.  Preference will be given to projects involving multicentre collaborations.  We are particularly interested in receiving applications related to areas of endocrinology the Trust has not supported previously.  A total sum of £50,000 is avail...
Source: Society for Endocrinology - April 25, 2014 Category: Endocrinology Source Type: news

Acromegaly, IGF1 bioactivity, and S-Klotho
The value of measuring IGF1 bioactivity in active acromegaly is unknown. Soluble Klotho (S-Klotho) level is elevated in active acromegaly and it has been suggested that S-Klotho can inhibit activation of the IGF1 receptor (IGF1R). A cross-sectional study was carried out in 15 patients with active acromegaly, finding that IGF1 bioactivity was within the reference range in a considerable number of subjects with active acromegaly and that elevated S-Klotho levels may have reduced IGF1 bioactivity. Moreover, IGF1 bioactivity was more strongly related to physical measures of QoL than total IGF1, suggesting that IGF1 bioactivity...
Source: Society for Endocrinology - April 25, 2014 Category: Endocrinology Source Type: news

Sharing your patient record can help researchers save and improve lives
The Society for Endocrinology is supporting a new campaign to raise awareness about the importance of sharing data from patient records with researchers. By allowing researchers access to the information contained within our records, we can contribute towards understanding the causes of disease and develop new and better medicines. Access to health data has played a major role in the Society's own project, such as the UK Acromegaly Register. This project, initially set up in 1997, collects prospective and retrospective data on patients with acromegaly to assess outcomes of surgery, radiotherapy and medica...
Source: Society for Endocrinology - January 14, 2014 Category: Endocrinology Source Type: news