Complementary comments on metastatic liver lesions with exceptional and rare cases
World J Gastroenterol. 2024 Feb 21;30(7):770-773. doi: 10.3748/wjg.v30.i7.770.ABSTRACTLiver metastases can appear in different forms in magnetic resonance imaging. Contrary to popular belief, while radiologists report hypovascular or hypervascular metastatic lesions, exceptional examples may be detected in various tumors. The aim of this article is to improve this review by presenting rare and atypical examples of liver metastasis, as well as cases that might potentially be misdiagnosed as metastases during the process of differential diagnosis.PMID:38515950 | PMC:PMC10950620 | DOI:10.3748/wjg.v30.i7.770 (Source: World Jou...
Source: World Journal of Gastroenterology : WJG - March 22, 2024 Category: Gastroenterology Authors: Kemal Bugra Memis Sonay Aydin Source Type: research

Erlotinib combination with a mitochondria-targeted ubiquinone effectively suppresses pancreatic cancer cell survival
CONCLUSION: Our findings suggest that a combination of erlotinib and MitoQ has the potential to suppress pancreatic tumor cell viability effectively.PMID:38515951 | PMC:PMC10950623 | DOI:10.3748/wjg.v30.i7.714 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - March 22, 2024 Category: Gastroenterology Authors: Pui-Yin Leung Wenjing Chen Anissa N Sari Poojitha Sitaram Pui-Kei Wu Susan Tsai Jong-In Park Source Type: research

Red cell distribution width/platelet ratio estimates the 3-year risk of decompensation in Metabolic Dysfunction-Associated Steatotic Liver Disease-induced cirrhosis
CONCLUSION: Altogether these findings suggest the RPR as a valid and potentially applicable non-invasive tool in the prediction of timing and modalities of decompensation in MASLD-related cACLD patients.PMID:38515952 | PMC:PMC10950628 | DOI:10.3748/wjg.v30.i7.685 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - March 22, 2024 Category: Gastroenterology Authors: Marcello Dallio Mario Romeo Paolo Vaia Salvatore Auletta Simone Mammone Marina Cipullo Luigi Sapio Angela Ragone Marco Niosi Silvio Naviglio Alessandro Federico Source Type: research

Endoscopic ultrasonography-related diagnostic accuracy and clinical significance on small rectal neuroendocrine neoplasms
World J Gastroenterol. 2024 Feb 21;30(7):774-778. doi: 10.3748/wjg.v30.i7.774.ABSTRACTThis research aimed to examine the diagnostic accuracy and clinical significance of endoscopic ultrasonography (EUS) in the context of small rectal neuroendocrine neoplasms (NENs). A total of 108 patients with rectal subepithelial lesions (SELs) with a diameter of < 20 mm were included in the analysis. The diagnosis and depth assessment of EUS was compared to the histology findings. The prevalence of NENs in rectal SELs was 78.7% (85/108). The sensitivity of EUS in detecting rectal NENs was 98.9% (84/85), while the specificity was 52.2...
Source: World Journal of Gastroenterology : WJG - March 22, 2024 Category: Gastroenterology Authors: Jun Weng Yu-Fan Chen Shu-Han Li Yan-Hua Lv Ruo-Bing Chen Guo-Liang Xu Shi-Yong Lin Kun-Hao Bai Source Type: research

Metformin and pancreatic neuroendocrine tumors: A systematic review and meta-analysis
CONCLUSION: T2DM represents a risk factor for the insurgence of pNET and is a significant predictor of poor post-treatment TFS of pNET patients. Unfortunately, a few studies with heterogeneous results limited the possibility of exploring the effect of metformin in the diagnosis and prognosis of pNET.PMID:38515954 | PMC:PMC10950617 | DOI:10.3748/wjg.v30.i7.759 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - March 22, 2024 Category: Gastroenterology Authors: Maja Cigrovski Berkovic Alessandro Coppola Vibor Sesa Anna Mrzljak Quirino Lai Source Type: research