Risk Factors of Revision Operation and Early Revision for Adjacent Segment Degeneration After Lumbar Fusion Surgery: A Case-Control Study
Adjacent segment degeneration (ASD) following lumbar fusion operation is common and can occur at varying timepoints after index surgery. An early revision operation for ASD, however, signifies a short symptom-free period and might increase the risk of successive surgeries. (Source: The Spine Journal)
Source: The Spine Journal - April 23, 2024 Category: Orthopaedics Authors: Sehan Park, Chang Ju Hwang, Dong-Ho Lee, Nam Yeop Kim, Hyun Wook Nam, Hyun Wook Kang, Choon Sung Lee, Cha Hyeong Ok, Jae Hwan Cho Tags: Clinical Study Source Type: research

Assessing the Variation and Drivers of Cost in 1-Level Lumbar Fusion: A Time-Driven Activity-Based Costing Analysis
As value-based health care arrangements gain traction in spine care, understanding the true cost of care becomes critical. Historically, inaccurate cost proxies have been used, including negotiated reimbursement rates or list prices. However, time-driven activity-based costing (TDABC) allows for a more accurate cost assessment, including a better understanding of the primary drivers of cost in 1-level lumbar fusion. (Source: The Spine Journal)
Source: The Spine Journal - April 23, 2024 Category: Orthopaedics Authors: David N. Bernstein, Bradley T. Hammoor, Chierika Ukogu Clements, Daniel G. Tobert, Thomas D. Cha, Jessica P. Aidlen, Stuart H. Hershman, Christopher M. Bono, Harold A. Fogel Tags: Clinical Study Source Type: research

Mind the Gap: Paramedian approach for coccygectomy
Coccydynia is pain in the coccyx that typically occurs idiopathically or from trauma. Most forms are self-limiting. However, if symptoms persist, non-surgical treatment options can include offloading, NSAIDs, physical therapy, and steroid injections. If all treatment options fail, a growing body of evidence supports a coccygectomy for symptomatic relief. The standard approach for a coccygectomy involves a midline incision cephalad to the anus along the gluteal cleft. Historically, this method has had high rates of infection. (Source: The Spine Journal)
Source: The Spine Journal - April 19, 2024 Category: Orthopaedics Authors: David Frolov, Kai Zhu, Maksim Rusev, Kyle Geiger, Carson Fuller, Miguel A Schmitz Tags: Clinical Study Source Type: research

Association Between Vertebral Endplate Defects and Patient-reported Symptoms: An Immunohistochemical Study Investigating the COX-2/PGE-2/EP-4 Axis
Low back pain is characterized by discomfort, muscle tension, or stiffness located between the ribcage and the upper part of the buttocks. Low back pain persisting>3 months is termed as chronic low back pain[1], which has become a worldwide problem affecting 70% to 90% of the world's population[2]. The etiology of chronic low back pain remains a puzzle[2]. Although a variety of anatomical structures can lead to pain, components of the lumbar spine are regarded as the primary sources, with the intervertebral disc having received the most attention[3,4]. (Source: The Spine Journal)
Source: The Spine Journal - April 15, 2024 Category: Orthopaedics Authors: Haojie Chen, Qingshuang Zhou, Xiaojiang Pu, Nannan Wang, Sinian Wang, Zhenhua Feng, Bin Wang, Zezhang Zhu, Yong Qiu, Xu Sun Tags: Clinical Study Source Type: research

Trunk Kinematic Analysis of Ascent and Descent Stairs in College Students with Idiopathic Scoliosis: A Case-Control Study
Traditional 3D motion analysis typically considers the spine as a rigid entity. Nevertheless, previous single-joint models have proven inadequate in evaluating the movement across different spinal segments in patients with idiopathic scoliosis (IS). Scoliosis significantly impairs movement functions, especially during activities such as ascending and descending stairs. There is a lack of research on the patterns of stair movement specifically for patients with IS. (Source: The Spine Journal)
Source: The Spine Journal - April 12, 2024 Category: Orthopaedics Authors: Yanyun GOU, Jing TAO, Huangwei LEI, Meijin HOU, Xiang CHEN, Xiangbin WANG Tags: Clinical Study Source Type: research

Erector Spinae Plane Block Level Does Not Impact Analgesic Efficacy in Enhanced Recovery for Lumbar Spine Surgery
Spine surgeries rank within the top three most painful procedures out of a total of 179 surgical interventions [1]. Pain is associated with stress and may lead to various postoperative complications by triggering heightened inflammation [2]. Patients experience moderate to severe pain on the first postoperative day, with a numerical rating scale (NRS) ranging from 5 to 8. Effective pain management can greatly improve patients ’ recovery and satisfaction and reduce hospitalization costs [3]. (Source: The Spine Journal)
Source: The Spine Journal - April 12, 2024 Category: Orthopaedics Authors: Jing-Yang Liou, Hsin-Yi Wang, Yu-Cheng Yao, Po-Hsin Chou, Chun-Sung Sung, Wei-Nung Teng, Fu-Wei Su, Mei-Yung Tsou, Chien-Kun Ting, Chun-Liang Lo Source Type: research

Generation of synthetic PET/MR fusion images from MR images using a combination of generative adversarial networks and conditional denoising diffusion probabilistic models based on simultaneous 18F-FDG PET/MR image data of pyogenic spondylodiscitis
Cross-modality image generation from magnetic resonance (MR) to positron emission tomography (PET) using the generative model can be expected to have complementary effects by addressing the limitations and maximizing the advantages inherent in each modality. (Source: The Spine Journal)
Source: The Spine Journal - April 12, 2024 Category: Orthopaedics Authors: Euijin Jung, Eunjung Kong, Dongwoo Yu, Heesung Yang, Philip Chicontwe, Sang Hyun Park, Ikchan Jeon Tags: Clinical Study Source Type: research

Optimal Timing of Starting Growing Rod Treatment for Early-onset Scoliosis
Growing rod (GR) systems require periodical surgical intervention and may cause associated complications, as well as worsened sagittal plane deformity. Generally, the risk of complications decreases with increment in age at the time of the index surgery with GR construct placement. However, the optimal timing to begin GR treatment has not reached a consensus yet. (Source: The Spine Journal)
Source: The Spine Journal - April 12, 2024 Category: Orthopaedics Authors: Sinian Wang, Xiaojiang Pu, Xu Sun, Bin Wang, Zezhang Zhu, Yong Qiu Tags: Clinical Study Source Type: research

Timing of intraoperative neurophysiological monitoring (IONM) recovery and clinical recovery after termination of pediatric spinal deformity surgery due to loss of IONM signals
Intraoperative neurophysiological monitoring (IONM) is routinely used to reduce the risk of neurological injury during spinal surgery, especially in cases that require deformity correction and instrumentation [1]. Transcranial motor evoked potentials (MEPs) and somatosensory-evoked potentials (SSEPs) allow real time assessment of motor and sensory pathways during surgery, and they have been recognized as reliable early markers in predicting nervous system integrity after spinal surgery [2,3]. (Source: The Spine Journal)
Source: The Spine Journal - April 11, 2024 Category: Orthopaedics Authors: Travis S. CreveCoeur, Rajiv R. Iyer, Hannah E. Goldstein, Mychael W. Delgardo, Todd C Hankinson, Mark A. Erickson, Sumeet Garg, David L Skaggs, Lindsay Andras, Benjamin C. Kennedy, Patrick J. Cahill, Lawrence G. Lenke, Peter D. Angevine, Benjamin D. Roye, Tags: Clinical Study Source Type: research

Impact of pelvic anteversion on spinopelvic alignment in an asymptomatic population: a dynamic perspective of standing and sitting
The pelvis, as the base of the spine, plays a key role in spinopelvic alignment. The morphology of the pelvis is described by the pelvic incidence (PI), which remains constant throughout adulthood. Previous studies have revealed the relationship between the PI and spine curvature. Specifically, a large PI is associated with a large degree of lumbar lordosis (LL) [1 –3], demonstrating the close correlation between pelvis morphology and spine curvature. Schwab et al [4] proposed a value for pelvic incidence minus lumbar lordosis (PI-LL) of (Source: The Spine Journal)
Source: The Spine Journal - April 10, 2024 Category: Orthopaedics Authors: Siyu Zhou, Yi Zhao, Zhuoran Sun, Gengyu Han, Fei Xu, Weipeng Qiu, Tongyu Liu, Weishi Li Source Type: research

Intervertebral disc injury triggers neurogenic inflammation of adjacent healthy discs
Intervertebral disc degeneration is common and may play a role in low back pain, but it is not well-understood. Previous studies have shown that the outer layer of the annulus fibrosus of a healthy disc is innervated by nociceptive nerve fibers. In the process of disc degeneration, it can grow into the inner annulus fibrosus or nucleus pulposus and release neuropeptides. Disc degeneration is associated with inflammation that produces inflammatory factors and potentiates nociceptor sensitization. (Source: The Spine Journal)
Source: The Spine Journal - April 10, 2024 Category: Orthopaedics Authors: Yongchao Li, Chen Dai, Bing Wu, Liang Yang, Xiujie Yan, Tanghua Liu, Jindong Chen, Zhaomin Zheng, Baogan Peng Tags: Basic Science Source Type: research

Reassessing the minimum two-year follow-up standard after lumbar decompression surgery: a 2-months follow-up seems to be an acceptable minimum
Academic orthopaedic journals and specialty societies emphasize the importance of two-year follow-up for patient-reported outcome measures (PROMS) after spine surgery, but there are limited data evaluating the appropriate length of follow-up. (Source: The Spine Journal)
Source: The Spine Journal - April 6, 2024 Category: Orthopaedics Authors: Anna-Katharina Calek, Bettina Hochreiter, Aaron J. Buckland Tags: Clinical Study Source Type: research

From 2D to 3D: Automatic Measurement of the Cobb Angle in Adolescent Idiopathic Scoliosis with the Weight-Bearing 3D Imaging
Adolescent idiopathic scoliosis (AIS) necessitates accurate spinal curvature assessment for effective clinical management. Traditional two-dimensional (2D) Cobb angle measurements have been the standard, but the emergence of three-dimensional (3D) automatic measurement techniques, such as those using weight-bearing 3D imaging (WR3D), presents an opportunity to enhance the accuracy and comprehensiveness of AIS evaluation. (Source: The Spine Journal)
Source: The Spine Journal - April 5, 2024 Category: Orthopaedics Authors: Zejun Liang, Qian Wang, Chunchao Xia, Zengtong Chen, Miao Xu, Guilun Liang, Yu Zhang, Chao Ye, Yiteng Zhang, Xiaocheng Yu, Hairong Wang, Han Zheng, Jing Du, Zhenlin Li, Jing Tang Source Type: research

The Relationship Between Paraspinal Muscle Atrophy and Degenerative Lumbar Spondylolisthesis at the L4/5 Level
Degenerative lumbar spondylolisthesis (DLS) is a prevalent spinal condition that can result in significant disability. DLS is thought to result from a combination of disc and facet joint degeneration, as well as various biological, biomechanical, and behavioral factors. One hypothesis is the progressive degeneration of segmental stabilizers, notably the paraspinal muscles, contributes to a vicious cycle of increasing slippage. (Source: The Spine Journal)
Source: The Spine Journal - April 1, 2024 Category: Orthopaedics Authors: Paul K öhli, Lukas Schönnagel, Jan Hambrecht, Jiaqi Zhu, Erika Chiapparelli, Ali E. Güven, Gisberto Evangelisti, Krizia Amoroso, Roland Duculan, Bernhard Michalski, Jennifer Shue, Koki Tsuchiya, Marco D. Burkhard, Andrew A. Sama, Federico P. Girardi, F Tags: Clinical Study Source Type: research

Surgical site infection following isolated lumbar discectomy increases odds of revision lumbar surgery within first 6 months, but not beyond
Lumbar discectomy is a commonly performed surgery following which surgical site infection (SSI) may occur. Prior literature has suggested that, following SSI related to lumbar fusion, the rate of subsequent lumbar surgeries is increased over prolonged periods of time. This has not been studied specifically for lumbar discectomy. (Source: The Spine Journal)
Source: The Spine Journal - April 1, 2024 Category: Orthopaedics Authors: Lucas Y Kim, Scott J Halperin, Jonathan N Grauer Source Type: research