Identification of celiac disease associated IgA nephropathy by IgA anti-tissue transglutaminase2 antibody deposits in archived formalin-fixed tissues
Conclusions: Co-localized IgA anti-TG2 deposits in the kidney biopsies in patients with IgAN help to establish a pathogenic link with CeD. A small proportion of patients with IgAN have associated CeD. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - January 25, 2023 Category: Gastroenterology Authors: Rimlee Dutta Ramakant Rawat Prasenjit Das Geetika Singh Alka Kumari Muzafer Ahmad Ashish Chauhan Vineet Ahuja Sanjay K Agrawal Govind K Makharia Source Type: research

In vitro and in vivo phototoxicity on gastric mucosa induced by methylene blue
Conclusions: Endoscopic light application with MB 0.5% concentration to the stomach may be regarded as a safe procedure despite some DNA injuries in the early period. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - January 25, 2023 Category: Gastroenterology Authors: Hui Yeong Oh Hyun Ho Choi Eui Jin Kim Ji Hye Choi Sung Sook Choi Hae Kyung Lee Hyung-Keun Kim Sang Woo Kim Won Sang H. Park Hiun Suk Chae Source Type: research

Acute myocardial infarction post-gastrointestinal bleeding: A clinical dilemma with poor prognosis
Conclusions: The in-hospital mortality of patients with GIB who subsequently develop AMI is high. White blood cell count, cardiogenic shock, and mechanical ventilator usage are independent predictors of in-hospital mortality. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - January 25, 2023 Category: Gastroenterology Authors: Xin Su Junlei Li Lijuan Du Yuzhen Wei Haiyu Li Haiqiang Sang Source Type: research

Serum 25-hydroxyvitamin D levels and the risk of non-alcoholic fatty liver: A two-sample Mendelian randomization study
Conclusion: This study indicates that serum 25(OH)D levels did not possess an obvious effect on the risk of NAFLD. The associations in previous studies may be due to residual confounding or reverse causation. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - January 25, 2023 Category: Gastroenterology Authors: Qi Sheng Huanchen Shi Shousheng Liu Likun Zhuang Zhenzhen Zhao Yongning Xin Source Type: research

Diagnostic performances of celiac disease serological tests among Saudi patients
Conclusions: IgA anti-TTG and EMA are excellent CD markers in children and adults. The use of IgA anti-TTG titers ≥10 × ULN and positive EMA as criteria for CD diagnosis in children and adults might be a good alternative to intestinal biopsy. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - January 25, 2023 Category: Gastroenterology Authors: Rim Sghiri Hana Ben Hassine Adel Almogren Zahid Shakoor Mohammed Alswayyed Source Type: research

Radiomics signature for prediction of long-term survival and recurrence patterns in patients with gastric cancer after radical gastrectomy: A multicenter study
Conclusions: The newly proposed radiomics score may be a powerful predictor of long-term outcomes and recurrence patterns of GC. Further studies are warranted to confirm these findings. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - January 25, 2023 Category: Gastroenterology Authors: Jing-Min Huang Lv-Ping Zhuang Hua-Gen Wang Li-Ying Zhong Sheng-Jin Xue Fang-Xi Tian Hua-Yang Lin Source Type: research

Factors and techniques associated with endoscopic retrograde cholangiopancreatography outcomes in patients with periampullary diverticulum: Results from a large tertiary center
Conclusions: PAD did not affect ERCP outcomes. However, the choice of techniques and AE prophylactic measures should be more specific, especially for patients with type I PAD. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - January 25, 2023 Category: Gastroenterology Authors: Chuanchao Xia Liqi Sun Lisi Peng Fang Cui Zhendong Jin Haojie Huang Source Type: research

Application and development of fecal microbiota transplantation in the treatment of gastrointestinal and metabolic diseases: A review
Hassan Mahmoudi, Hadi HossainpourSaudi Journal of Gastroenterology 2023 29(1):3-11 Fecal microbiota transplantation (FMT) restores a balanced intestinal flora, which helps to cure recurrent Clostridium difficile infections (RCDI). FMT has also been used to treat other gastrointestinal diseases, including inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), and chronic constipation, as well as a variety of non-GI disorders. The purpose of this review is to discuss gut microbiota and FMT treatment of GI and non-GI diseases. An imbalanced gut microbiota is known to predispose one to Clostridium difficile infecti...
Source: The Saudi Journal of Gastroenterology - January 25, 2023 Category: Gastroenterology Authors: Hassan Mahmoudi Hadi Hossainpour Source Type: research

Periampullary diverticulum in endoscopic retrograde cholangiopancreatography: A paper tiger ?
Tarek Z Arabi, Aymen AlmuhaidbSaudi Journal of Gastroenterology 2023 29(1):1-2 (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - January 25, 2023 Category: Gastroenterology Authors: Tarek Z Arabi Aymen Almuhaidb Source Type: research

Aberrant DNA methylation and expression of EYA4 in gastric cardia intestinal metaplasia
Conclusions: Detection rates of gastric cardiac IM increase with age and are higher in men. Our findings highlight the important role of promoter hypermethylation and downregulation of EYA4 in gastric cardiac IM development. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - November 24, 2022 Category: Gastroenterology Authors: Chenxi Li Zhaohui Liu Guohua Xu Shibin Wu Yunhui Peng Ruinuan Wu Shukun Zhao Xiaoqi Liao Runhua Lin Source Type: research

The impact of inflammatory bowel diseases on the quality of life of Saudi pediatric patients: A cross-sectional study
Conclusions: Pediatric IBD patients have significantly lower HrQOL scores than healthy children. Disease activity was found to be a predictor for poor HrQOL outcome. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - November 24, 2022 Category: Gastroenterology Authors: Abdulhamid A Alhadab Shaden N AlMahamed Ibrahim E Hassan Abdelhai H Hammo Source Type: research

Comparison of the diagnostic accuracy of the updated Sydney system and single biopsy
Conclusion: Taking biopsies in accordance with the USS had higher sensitivity in detecting atrophic gastritis with or without IM compared to single biopsy. One or two biopsies is not sufficient to identify patients for whom endoscopic follow-up is recommended. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - November 24, 2022 Category: Gastroenterology Authors: Cundullah Torun Arda Yavuz Kubra Akan Hatice Seneldir Ayse Nur Toksoz Hak Celal Ulasoglu Ilyas Tuncer Source Type: research

Oxidative stress and the importance of H. pylori eradication in patients with functional dyspepsia
Conclusion: The inflammation caused by H. pylori shifted the thiol–disulphide equilibrium in the cell redox system towards the direction of disulphide. The study findings suggest that the restoration of the said hemostatic balance with eradication therapy relieved the organism from oxidative stress. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - November 24, 2022 Category: Gastroenterology Authors: Berat Ebik Nihat Aslan Naz & #305;m Ekin Ferhat Bacaksiz Medeni Arpa Salim Neselioglu Ozcan Erel Feyzullah Ucmak Source Type: research

Transient elastography for the prevalence of non-alcoholic fatty liver disease in patients with type 2 diabetes: Evidence from the CORDIAL cohort study
Conclusions: Our results demonstrate an increase in prevalence of NAFLD in Saudi patients with T2DM, based on transient elastography and CAP score. The risk of NAFLD appears to be higher in T2DM patients with abdominal obesity, elevated SBP, and increased ALT levels, which supports the screening of these conditions in patients with T2DM. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - November 24, 2022 Category: Gastroenterology Authors: Assim A Alfadda Suphia M Sherbeeni Adel N Alqutub Abdullah S Aldosary Nasser M Aldaghri Simon D Taylor-Robinson Saleh A Alqahtani Rukhsana Gul Abdulrahman M Almaghamsi Source Type: research

Cholecystectomy reduces the severity of subsequent idiopathic acute pancreatitis
Conclusion: Cholecystectomy could reduce the severity of subsequent idiopathic AP and the frequency of biliary pancreatitis. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - November 24, 2022 Category: Gastroenterology Authors: Jing Lei Feng Xu Haiyan Cao Zhihang Zhou Song He Source Type: research