The Diagnosis and Treatment of Adult Urinary Tract Infections in the Emergency Department
Emerg Med Clin North Am. 2024 May;42(2):209-230. doi: 10.1016/j.emc.2024.01.001. Epub 2024 Mar 7.ABSTRACTEmergency medicine has been called the art of "making complicated clinical decisions with limited information." This description is particularly relevant in the case of diagnosis and treatment of urinary tract infections (UTIs). Although common, UTIs are often challenging to diagnose given the presence of non-specific signs and symptoms and over-reliance on laboratory findings. This review provides an interdisciplinary interpretation of the primary literature and practice guidelines, with a focus on diagnostic and antim...
Source: The Medical Clinics of North America - April 19, 2024 Category: General Medicine Authors: Robert Redwood Kimberly C Claeys Source Type: research

Optimizing Diagnosis and Management of Community-acquired Pneumonia in the Emergency Department
Emerg Med Clin North Am. 2024 May;42(2):231-247. doi: 10.1016/j.emc.2024.02.001. Epub 2024 Mar 12.ABSTRACTPneumonia is split into 3 diagnostic categories: community-acquired pneumonia (CAP), health care-associated pneumonia, and ventilator-associated pneumonia. This classification scheme is driven not only by the location of infection onset but also by the predominant associated causal microorganisms. Pneumonia is diagnosed in over 1.5 million US emergency department visits annually (1.2% of all visits), and most pneumonia diagnosed by emergency physicians is CAP.PMID:38641389 | DOI:10.1016/j.emc.2024.02.001 (Source: The M...
Source: The Medical Clinics of North America - April 19, 2024 Category: General Medicine Authors: Katherine M Hunold Elizabeth Rozycki Nathan Brummel Source Type: research

Orthopedic Articular and Periarticular Joint Infections
Emerg Med Clin North Am. 2024 May;42(2):249-265. doi: 10.1016/j.emc.2024.01.002. Epub 2024 Mar 2.ABSTRACTAcute nontraumatic joint pain has an extensive differential. Emergency physicians must be adept at identifying limb and potentially life-threatening infection. Chief among these is septic arthritis. In addition to knowing how these joint infections typically present, clinicians need to be aware of host and pathogen factors that can lead to more insidious presentations and how these factors impact the interpretation of diagnostic tests.PMID:38641390 | DOI:10.1016/j.emc.2024.01.002 (Source: The Medical Clinics of North America)
Source: The Medical Clinics of North America - April 19, 2024 Category: General Medicine Authors: Pim Jetanalin Yanint Raksadawan Pholaphat Charles Inboriboon Source Type: research

Diabetic Foot Infections in the Emergency Department
Emerg Med Clin North Am. 2024 May;42(2):267-285. doi: 10.1016/j.emc.2024.01.003. Epub 2024 Mar 4.ABSTRACTDiabetic foot infection (DFI) is among the most common diabetic complications requiring hospitalization. Prompt emergency department diagnosis and evidence-based management can prevent eventual amputation and associated disability and mortality. Underlying neuropathy, arterial occlusion, immune dysfunction, and hyperglycemia-associated dehydration and ketoacidosis can all contribute to severity and conspire to make DFI diagnosis and management difficult. Serious complications include osteomyelitis, necrotizing infection...
Source: The Medical Clinics of North America - April 19, 2024 Category: General Medicine Authors: Bradley W Frazee Source Type: research

Tick-Borne Diseases
Emerg Med Clin North Am. 2024 May;42(2):287-302. doi: 10.1016/j.emc.2024.01.004. Epub 2024 Feb 29.ABSTRACTTicks are responsible for the vast majority of vector-borne illnesses in the United States. The number of reported tick-borne disease (TBD) cases has more than doubled in the past 20 years. The majority of TBD cases occur in warm weather months in individuals with recent outdoor activities in wooded areas. The risk of contracting a TBD is also highly dependent on geographic location. Between 24 and 48 hours of tick attachment is required for most disease transmission to occur. Only 50% to 70% of patients with a TBD wil...
Source: The Medical Clinics of North America - April 19, 2024 Category: General Medicine Authors: Wesley Eilbert Andrew Matella Source Type: research

Fever and Rash
Emerg Med Clin North Am. 2024 May;42(2):303-334. doi: 10.1016/j.emc.2024.01.005. Epub 2024 Mar 7.ABSTRACTInfectious causes of fever and rash pose a diagnostic challenge for the emergency provider. It is often difficult to discern rashes associated with rapidly progressive and life-threatening infections from benign exanthems, which comprise the majority of rashes seen in the emergency department. Physicians must also consider serious noninfectious causes of fever and rash. A correct diagnosis depends on an exhaustive history and head-to-toe skin examination as most emergent causes of fever and rash remain clinical diagnose...
Source: The Medical Clinics of North America - April 19, 2024 Category: General Medicine Authors: Richard Diego Gonzales Y Tucker Aravind Addepalli Source Type: research

Sexually Transmitted Infections in the Emergency Department
Emerg Med Clin North Am. 2024 May;42(2):335-368. doi: 10.1016/j.emc.2024.02.006.ABSTRACTAs the United States faces a worsening epidemic of sexually transmitted infections (STIs), emergency departments (EDs) play a critical role in identifying and treating these infections. The growing health inequities in the distribution and disproportionate impact of STIs add to the urgency of providing high-quality sexual health care through the ED. Changes in population health are reflected in the new Centers for Disease Control recommendations on screening, diagnostic testing, and treatment of STIs. This review covers common, as well ...
Source: The Medical Clinics of North America - April 19, 2024 Category: General Medicine Authors: Rachel E Solnick Laura Hernando L ópez Patricia Mae Martinez Jason E Zucker Source Type: research

Communicable Disease Screening and Human Immunodeficiency Virus Prevention in the Emergency Department
Emerg Med Clin North Am. 2024 May;42(2):369-389. doi: 10.1016/j.emc.2024.02.007. Epub 2024 Mar 19.ABSTRACTEmergency departments (ED) provide care to populations with high rates of communicable diseases, like HIV, hepatitis C virus, and syphilis. For many patients, the ED is their sole entry point into the healthcare system and they do not routinely access screening and prevention services elsewhere. As such, the ED can serve an important public health role through communicable disease identification, treatment, and prevention. In this article, we examine national recommendations, peer-reviewed literature, and expert consen...
Source: The Medical Clinics of North America - April 19, 2024 Category: General Medicine Authors: Douglas A E White Rachel E Solnick Source Type: research

The Intersection of Substance Use Disorders and Infectious Diseases in the Emergency Department
Emerg Med Clin North Am. 2024 May;42(2):391-413. doi: 10.1016/j.emc.2024.02.004. Epub 2024 Mar 12.ABSTRACTSubstance use disorders (SUDs) intersect clinically with many infectious diseases, leading to significant morbidity and mortality if either condition is inadequately treated. In this article, we will describe commonly seen SUDs in the emergency department (ED) as well as their associated infectious diseases, discuss social drivers of patient outcomes, and introduce novel ED-based interventions for co-occurring conditions. Clinicians should come away from this article with prescriptions for both antimicrobial medication...
Source: The Medical Clinics of North America - April 19, 2024 Category: General Medicine Authors: Erik S Anderson Bradley W Frazee Source Type: research

Coronavirus Disease 2019: Past, Present, and Future
This article seeks to offer lessons learned from the pandemic, summarize best evidence for current management of patients with COVID-19, and give insights into future directions with this disease.PMID:38641397 | DOI:10.1016/j.emc.2024.02.002 (Source: The Medical Clinics of North America)
Source: The Medical Clinics of North America - April 19, 2024 Category: General Medicine Authors: Charlotte Page Wills Berenice Perez Justin Moore Source Type: research

Optimizing Antimicrobial Stewardship in the Emergency Department
Emerg Med Clin North Am. 2024 May;42(2):443-459. doi: 10.1016/j.emc.2024.02.003. Epub 2024 Mar 12.ABSTRACTAntibiotic stewardship is a core component of emergency department (ED) practice and impacts patient safety, clinical outcomes, and public health. The unique characteristics of ED practice, including crowding, time pressure, and diagnostic uncertainty, need to be considered when implementing antibiotic stewardship interventions in this setting. Rapid advances in pathogen detection and host response biomarkers promise to revolutionize the diagnosis of infectious diseases in the ED, but such tests are not yet considered ...
Source: The Medical Clinics of North America - April 19, 2024 Category: General Medicine Authors: Julia Sapozhnikov Fritzie S Albarillo Michael S Pulia Source Type: research

Managing Antimicrobial Resistance in the Emergency Department
Emerg Med Clin North Am. 2024 May;42(2):461-483. doi: 10.1016/j.emc.2024.02.005. Epub 2024 Mar 15.ABSTRACT(Basic awareness and understanding of antimicrobial resistance and prevailing mechanisms can aid emergency physicians in providing appropriate care to patients with infections due to a multidrug-resistant organism (MDRO). Empiric treatment of MDRO infections should be approached with caution and guided by the most likely pathogens based on differential diagnosis, severity of the illness, suspected source of infection, patient-specific factors, and local antibiotic susceptibility patterns. Newer broad-spectrum antibioti...
Source: The Medical Clinics of North America - April 19, 2024 Category: General Medicine Authors: Julianne Yeary Larissa Hacker Stephen Y Liang Source Type: research

Infectious Disease Emergencies
Emerg Med Clin North Am. 2024 May;42(2):xiii-xiv. doi: 10.1016/j.emc.2024.02.024. Epub 2024 Mar 8.NO ABSTRACTPMID:38641400 | DOI:10.1016/j.emc.2024.02.024 (Source: The Medical Clinics of North America)
Source: The Medical Clinics of North America - April 19, 2024 Category: General Medicine Authors: Amal Mattu Source Type: research

Frontiers in Emergency Department Infectious Disease Management
Emerg Med Clin North Am. 2024 May;42(2):xv-xvii. doi: 10.1016/j.emc.2024.02.009. Epub 2024 Feb 23.NO ABSTRACTPMID:38641401 | DOI:10.1016/j.emc.2024.02.009 (Source: The Medical Clinics of North America)
Source: The Medical Clinics of North America - April 19, 2024 Category: General Medicine Authors: Bradley W Frazee Michael S Pulia Christopher M Colbert Source Type: research

Sleep and Overactive Bladder in Parkinson's Disease
Urol Clin North Am. 2024 May;51(2):197-207. doi: 10.1016/j.ucl.2024.02.005. Epub 2024 Mar 10.ABSTRACTPatients with Parkinson's disease (PD) have disturbances in their bladder and sleep physiology that lead to nocturia and overactive bladder (OAB). These symptoms can be extremely bothersome and impact not only their quality of life (QoL) but also the QoL of their caretakers. We aim to highlight the changes in bladder and sleep physiology in PD and explore OAB/nocturia treatment strategies in this population.PMID:38609192 | DOI:10.1016/j.ucl.2024.02.005 (Source: The Medical Clinics of North America)
Source: The Medical Clinics of North America - April 12, 2024 Category: General Medicine Authors: Yu Zheng Anne P Cameron Source Type: research