Survey of Wound-Healing Centers and Wound Care Units in China
The purpose of this study is to report the Chinese experience of establishing hospital-based wound care centers over 15 years. A total of 69 wound-healing centers (WHCs) and wound care units (WCUs) were involved. Questionnaires were diverged to the principal directors of these sites; data extracted for this study included origin, year of establishment, medical staff, degree of hospitals, wound etiology, wound-healing rate, hospital stay, and outcomes data. The period of data extraction was defined as before and after 1 year of the establishment of WHCs and WCUs. The earliest WHC was established in 1999, and from 2010 the s...
Source: The International Journal of Lower Extremity Wounds - August 9, 2016 Category: Surgery Authors: Jiang, Y., Xia, L., Jia, L., Fu, X. Tags: News Item Source Type: research

Multiple Neuromas Cause Painful "Jumping Stump" in a Transfemoral Amputee: A Case Report
In this study, we describe a 38-year-old man with bilateral transfemoral amputee who suffered from painful "jumping stump" with multiple neuromas confirmed by imaging. He was treated successfully by ultrasound-guided phenol injection into the sciatic neuroma stalks. The pathophysiology of jumping stump and its possible association with neuroma are briefly discussed. (Source: The International Journal of Lower Extremity Wounds)
Source: The International Journal of Lower Extremity Wounds - August 9, 2016 Category: Surgery Authors: Buntragulpoontawee, M., Pattamapaspong, N., Tongprasert, S. Tags: Case Reports Source Type: research

Knee and Ankle Reconstruction With Reverse Anterolateral Thigh and Free Anterolateral Thigh Flap From One Donor Site
Traditionally, the anterolateral thigh (ALT) free flap is used in distal lower extremity reconstruction. Reverse ALT flap has become one of the most popular choices for knee joint soft tissue defects. A 53-year-old man sustained a degloving injury in the right lateral side of the lower extremity from the lateral malleolar area to the knee joint area. The contamination was severe, necessitating serial debridement and negative pressure wound therapy. After 4 weeks, no more soft tissue necrosis was evident. No more microorganism growth was confirmed by swab culture. ALT free flap using proximal perforator was planned for late...
Source: The International Journal of Lower Extremity Wounds - August 9, 2016 Category: Surgery Authors: Choi, K., Cho, J., Park, M., Park, D. H., Lee, I. J. Tags: Case Reports Source Type: research

Multisystemic Sarcoidosis Presenting as Pretibial Leg Ulcers
We report the case of a 45-year-old female patient with chronic multisystemic sarcoidosis presenting with pretibial leg ulcers. Other etiology could be excluded. Histology revealed nonspecific findings. Therefore, the diagnosis of nonspecific leg ulcers in sarcoidosis was confirmed. Treatment consisted of oral prednisolone and good ulcer care. Complete healing was achieved within 6 months. Sarcoidosis is a rare cause of leg ulcers and usually sarcoid granulomas can be found. Our patient illustrates that even in the absence of sarcoid granulomas, leg ulcers can be due to sarcoidosis. (Source: The International Journal of Lo...
Source: The International Journal of Lower Extremity Wounds - August 9, 2016 Category: Surgery Authors: Wollina, U., Baunacke, A., Hansel, G. Tags: Case Reports Source Type: research

Zinc-Responsive Necrolytic Acral Erythema in a Patient With Psoriasis: A Rare Case
We present the case of a 60-year-old man with a history of psoriasis and chronic HCV infection, who developed new lesions of NAE extending from previous elephantine psoriatic plaques on bilateral lower legs. According to previous reports, resolution of NAE has been successfully achieved by treatment of the underlying HCV infection, or the use of oral zinc therapy. Our patient exhibited good response to zinc therapy. By reporting this case, we would like to raise the awareness of physicians to this unique acrally distributed dermatosis, which is distinct from psoriasis by its pathological feature of aggregated necrotic kera...
Source: The International Journal of Lower Extremity Wounds - August 9, 2016 Category: Surgery Authors: Hou, Y.-C., Wu, C.-Y. Tags: Case Reports Source Type: research

Early and Thorough Wound Debridement Is Crucial for Treatment of Patients With Thermal Burns and para-Chloronitrobenzene Poisoning
para-Chloronitrobenzene (p-CNB) is one of the important chemicals with high liposolubility and oxidizing properties. Heated p-CNB liquid can cause thermal injury by absorption over skin and wound and even methemoglobinemia by conversion of hemoglobin into methemoglobin. Severe methemoglobinemia is a life-threatening condition that demands immediate treatment. It is very rare for individuals to be injured by heated p-CNB, but they should be carefully attended to because of the peculiarities of this kind of injury. In the past 10 years, we received 5 patients who were injured by heated p-CNB. In addition to the intravenous a...
Source: The International Journal of Lower Extremity Wounds - August 9, 2016 Category: Surgery Authors: Zhang, Y., Wang, X., Ni, L., Ye, C., Zhang, J., Han, C., Yu, C. Tags: Case Reports Source Type: research

Ozone Ameliorates Doxorubicine-Induced Skin Necrosis - results from an animal model
Doxorubicin (DXR) extravasation result with serious morbidity like skin ulceration and necrosis. The purpose of this study is to determine the protective effects of ozone, olive oil, dimethyl sulfoxide (DMSO), and coenzyme Q10 in the treatment of DXR-induced skin ulcers on rats. After an intradermal injection of DXR on a basis of an animal extravasation model, the materials were topically applied. The ulcer sizes were measured, and a punch biopsy was taken from the extravasation site in which the skin ulcers formed at the end of the experiment. The samples were analyzed for tumor necrosis factor alpha (TNF-α), interl...
Source: The International Journal of Lower Extremity Wounds - August 9, 2016 Category: Surgery Authors: Kesik, V., Yuksel, R., Yigit, N., Saldir, M., Karabacak, E., Erdem, G., Babacan, O., Gulgun, M., Korkmazer, N., Bayrak, Z. Tags: Basic and Experimental Research Source Type: research

Anti-inflammatory and Wound Healing Activities of Aloe vera, Honey and Milk Ointment on Second-Degree Burns in Rats
The aim of the present study was morphological and morphometric investigation of burn healing impacts of an honey, milk, and Aloe vera (HMA) ointment on experimentally induced second-degree burns, to approve the medicinal basis of its use in Iranian traditional medicine. A total of 21 male Albino rats weighing 200 to 300 g were divided into 3 groups of 7, including (1) control group, (2) positive control group, and (3) the treatment group that were treated with eucerin, silver sulfadiazine 3% and HMA ointment 5% respectively.After anesthetizing, the second-degree burns (1 cm2 areas) were made on the back of the animals usi...
Source: The International Journal of Lower Extremity Wounds - August 9, 2016 Category: Surgery Authors: Farzadinia, P., Jofreh, N., Khatamsaz, S., Movahed, A., Akbarzadeh, S., Mohammadi, M., Bargahi, A. Tags: Basic and Experimental Research Source Type: research

Variation and Trends in Lower Extremity Amputation Rates in Los Angeles County Hospitals 2000-2010
This study demonstrated that health care systems and hospitals are associated with significant disparity in LEA rates among socioeconomic groups and geographical regions. (Source: The International Journal of Lower Extremity Wounds)
Source: The International Journal of Lower Extremity Wounds - August 9, 2016 Category: Surgery Authors: Jindeel, A., Gessert, C., Johnson, B. P. Tags: Clinical and Translational Research Source Type: research

Factors Affecting Mortality After Major Nontraumatic Lower Extremity Amputation
Our aim was to evaluate the factors affecting the mortality of patients who underwent nontraumatic major lower limb amputation due to ischemic and/or diabetic causes. A total of 100 patients were included in the study. Among these patients, 70 (70%) underwent below-knee amputation, whereas 30 (30%) underwent above-knee amputation. Eleven (15.7%) of the 70 patients who underwent below-knee amputation and 12 (40%) of the 30 patients who underwent above-knee amputation (P = .008) were deceased. After multivariable Poisson regression analysis, female gender (risk ratio [RR] = 2.00, 95% CI = 1.07-3.74) and a neutrophil lymphocy...
Source: The International Journal of Lower Extremity Wounds - August 9, 2016 Category: Surgery Authors: Dinc, T., Polat Duzgun, A., Kayilioglu, S. I., Erdogan, A., Yavuz, Z., Coskun, F. Tags: Clinical and Translational Research Source Type: research

Anemia in Patients With Diabetic Foot Ulcer: Prevalence, Clinical Characteristics, and Outcome
In this study, 353 subjects were included, anemia was present in 236 patients (66.9%). These patients were significantly male, more likely to be a smoker, had a lower level of serum albumin and worse kidney function, more likely to use at least 2 types of antibiotics and had a worse perfusion of the lower limb, a larger and deeper ulcer and a more severe infection. A multivariate analysis showed that male sex, lower serum albumin, and worse kidney function were independent predictors of anemia in DFU patients. Additionally, in multivariate models, anemia was one of the variables that was most significantly associated with ...
Source: The International Journal of Lower Extremity Wounds - August 9, 2016 Category: Surgery Authors: Chuan, F., Zhang, M., Yao, Y., Tian, W., He, X., Zhou, B. Tags: Clinical and Translational Research Source Type: research

Interobserver Reliability of Three Validated Scoring Systems in the Assessment of Diabetic Foot Ulcers
Scoring systems for diabetic foot ulcers may be used for clinical purposes, research or audit, to help assess disease severity, plan management, and even predict outcomes. While many have been validated in study populations, little is known about their interobserver reliability. This prospective study aimed to evaluate interobserver reliability of 3 scoring systems for diabetic foot ulceration. After sharp debridement, diabetic foot ulcers were classified by a multidisciplinary pool of trained observers, using the PEDIS (Perfusion, Extent, Depth, Infection, Sensation), SINBAD (Site, Ischemia, Neuropathy, Bacterial infectio...
Source: The International Journal of Lower Extremity Wounds - August 9, 2016 Category: Surgery Authors: Forsythe, R. O., Ozdemir, B. A., Chemla, E. S., Jones, K. G., Hinchliffe, R. J. Tags: Clinical and Translational Research Source Type: research

Clinical Efficacy Test of Polyester Containing Herbal Extract Dressings in Burn Wound Healing
Technological advancement has assisted in developing various availabilities of wound products that help in not only in healing and preventing infection but also in providing patients’ comfort and pain reduction during application. However, most of advanced wound healing products in Thailand were imported at high costs to patients. Nowadays, there are increased numbers of local researches of herbs that could provide healing environment for successful wound care. Herbal wound products are currently being introduced as alternatives to those imported dressings. The aim of this study was to report the clinical efficacy of...
Source: The International Journal of Lower Extremity Wounds - August 9, 2016 Category: Surgery Authors: Muangman, P., Praditsuktavorn, B., Chinaroonchai, K., Chuntrasakul, C. Tags: Clinical and Translational Research Source Type: research

An Investigation of Diabetes Knowledge Levels Between Newly Diagnosed Type 2 Diabetes Patients in Galway, Ireland and New York, USA: A Cross-Sectional Study
Management of diabetes mellitus (DM) involves podiatrists as the primary practitioners engaged in prevention and treatment of lower limb pathology. Patients must first possess adequate knowledge to engage in effective self-management. A knowledge assessment of a DM cohort has never before been conducted in Ireland. The primary research objective was to determine the existence of gaps in specific areas of DM-related knowledge between type 2 DM (T2DM) patients in Galway (GW) and New York (NY). A cross-sectional study compared DM-related knowledge levels between 2 cohorts over a 10-week period. Participants were recently (<...
Source: The International Journal of Lower Extremity Wounds - August 9, 2016 Category: Surgery Authors: Mahon, A. M., Moore, G. D., Gazes, M. I., Chusid, E., MacGilchrist, C. Tags: Clinical and Translational Research Source Type: research

WUWHS 2016: What Promises for the Future?
(Source: The International Journal of Lower Extremity Wounds)
Source: The International Journal of Lower Extremity Wounds - August 9, 2016 Category: Surgery Authors: Rerkasem, K., Mani, R. Tags: Editorial Source Type: research