Reduced plasma glycine concentration in healthy and chronically diseased older adults: a marker of visceral adiposity?
CONCLUSIONS: Reduced plasma Gly in older adults can be viewed as a marker of visceral adiposity, independent of sex, age, body composition, presence of chronic disease, and whole body glycine production or clearance.CLINICAL TRIAL REGISTRY: In the present paper, we report the analysis of the baseline measurements from the following studies registered on ClinicalTrials.gov.PMID:38616018 | DOI:10.1016/j.ajcnut.2024.04.008 (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - April 14, 2024 Category: Nutrition Authors: Lars N J Deutz Raven A Wierzchowska-McNew Nicolaas E P Deutz Mari ëlle P K J Engelen Source Type: research

Replacement of saturated fatty acids from meat by dairy sources in relation to incident cardiovascular disease: The European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk study
CONCLUSIONS: Findings indicate that different SFA-rich foods at baseline have differential associations with CVD risk. If confirmed by further studies, these findings could be used to inform specific food-based dietary guidance.PMID:38608753 | DOI:10.1016/j.ajcnut.2024.04.007 (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - April 12, 2024 Category: Nutrition Authors: Yakima D Vogtschmidt Sabita S Soedamah-Muthu Fumiaki Imamura David I Givens Julie A Lovegrove Source Type: research

Associations of Serum 25-hydroxyvitamin D and Vitamin D Receptor Polymorphisms with Risks of Cardiovascular Disease and Mortality among Patients with Chronic Kidney Disease: A Prospective Study
CONCLUSIONS: Higher serum 25(OH)D concentrations were significantly associated with lower risks of total and subtypes of CVD incidence and mortality among individuals with CKD. These findings highlight the importance of maintaining adequate vitamin D status in the prevention of CVD and mortality in patients with CKD.PMID:38608754 | DOI:10.1016/j.ajcnut.2024.04.001 (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - April 12, 2024 Category: Nutrition Authors: Shiyu Zhao Xue Chen Zhenzhen Wan Tingting Geng Qi Lu Hancheng Yu Xiaoyu Lin An Pan Gang Liu Source Type: research

Replacement of saturated fatty acids from meat by dairy sources in relation to incident cardiovascular disease: The European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk study
CONCLUSIONS: Findings indicate that different SFA-rich foods at baseline have differential associations with CVD risk. If confirmed by further studies, these findings could be used to inform specific food-based dietary guidance.PMID:38608753 | DOI:10.1016/j.ajcnut.2024.04.007 (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - April 12, 2024 Category: Nutrition Authors: Yakima D Vogtschmidt Sabita S Soedamah-Muthu Fumiaki Imamura David I Givens Julie A Lovegrove Source Type: research

Associations of Serum 25-hydroxyvitamin D and Vitamin D Receptor Polymorphisms with Risks of Cardiovascular Disease and Mortality among Patients with Chronic Kidney Disease: A Prospective Study
CONCLUSIONS: Higher serum 25(OH)D concentrations were significantly associated with lower risks of total and subtypes of CVD incidence and mortality among individuals with CKD. These findings highlight the importance of maintaining adequate vitamin D status in the prevention of CVD and mortality in patients with CKD.PMID:38608754 | DOI:10.1016/j.ajcnut.2024.04.001 (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - April 12, 2024 Category: Nutrition Authors: Shiyu Zhao Xue Chen Zhenzhen Wan Tingting Geng Qi Lu Hancheng Yu Xiaoyu Lin An Pan Gang Liu Source Type: research

Associations Among Diabetes Medication Use, Serum Magnesium, and Insulin Resistance in a Cohort of Older Puerto Rican Adults
CONCLUSIONS: Diabetes medication, especially metformin, was associated with elevated odds of hypomagnesemia, which may weaken the association between metformin and lowering of HOMA-IR. The causal inference needs to be confirmed in further studies.PMID:38599521 | DOI:10.1016/j.ajcnut.2024.04.005 (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - April 10, 2024 Category: Nutrition Authors: Fan Chen Kelsey M Mangano Mahdi Garelnabi Kellee Cardaleen Katherine L Tucker Source Type: research

Plant-based meat analogues (PBMAs) and their effects on cardiometabolic health: An 8-week randomized controlled trial comparing PBMAs with their corresponding animal-based foods
CONCLUSIONS: A plant-based meat analogues diet did not show widespread cardiometabolic health benefits compared with omnivorous diets over 8 weeks. The composition of PBMAs may need to be considered in future trials.CLINICAL TRIAL REGISTRATION: https://clinicaltrials.gov/ TRIAL REGISTRATION NUMBER: NCT05446753.PMID:38599522 | DOI:10.1016/j.ajcnut.2024.04.006 (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - April 10, 2024 Category: Nutrition Authors: Darel Wee Kiat Toh Amanda Simin Fu Kervyn Ajay Mehta Nicole Yi Lin Lam Sumanto Haldar Christiani Jeyakumar Henry Source Type: research

Associations Among Diabetes Medication Use, Serum Magnesium, and Insulin Resistance in a Cohort of Older Puerto Rican Adults
CONCLUSIONS: Diabetes medication, especially metformin, was associated with elevated odds of hypomagnesemia, which may weaken the association between metformin and lowering of HOMA-IR. The causal inference needs to be confirmed in further studies.PMID:38599521 | DOI:10.1016/j.ajcnut.2024.04.005 (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - April 10, 2024 Category: Nutrition Authors: Fan Chen Kelsey M Mangano Mahdi Garelnabi Kellee Cardaleen Katherine L Tucker Source Type: research

Plant-based meat analogues (PBMAs) and their effects on cardiometabolic health: An 8-week randomized controlled trial comparing PBMAs with their corresponding animal-based foods
CONCLUSIONS: A plant-based meat analogues diet did not show widespread cardiometabolic health benefits compared with omnivorous diets over 8 weeks. The composition of PBMAs may need to be considered in future trials.CLINICAL TRIAL REGISTRATION: https://clinicaltrials.gov/ TRIAL REGISTRATION NUMBER: NCT05446753.PMID:38599522 | DOI:10.1016/j.ajcnut.2024.04.006 (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - April 10, 2024 Category: Nutrition Authors: Darel Wee Kiat Toh Amanda Simin Fu Kervyn Ajay Mehta Nicole Yi Lin Lam Sumanto Haldar Christiani Jeyakumar Henry Source Type: research

Associations Among Diabetes Medication Use, Serum Magnesium, and Insulin Resistance in a Cohort of Older Puerto Rican Adults
CONCLUSIONS: Diabetes medication, especially metformin, was associated with elevated odds of hypomagnesemia, which may weaken the association between metformin and lowering of HOMA-IR. The causal inference needs to be confirmed in further studies.PMID:38599521 | DOI:10.1016/j.ajcnut.2024.04.005 (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - April 10, 2024 Category: Nutrition Authors: Fan Chen Kelsey M Mangano Mahdi Garelnabi Kellee Cardaleen Katherine L Tucker Source Type: research

Plant-based meat analogues (PBMAs) and their effects on cardiometabolic health: An 8-week randomized controlled trial comparing PBMAs with their corresponding animal-based foods
CONCLUSIONS: A plant-based meat analogues diet did not show widespread cardiometabolic health benefits compared with omnivorous diets over 8 weeks. The composition of PBMAs may need to be considered in future trials.CLINICAL TRIAL REGISTRATION: https://clinicaltrials.gov/ TRIAL REGISTRATION NUMBER: NCT05446753.PMID:38599522 | DOI:10.1016/j.ajcnut.2024.04.006 (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - April 10, 2024 Category: Nutrition Authors: Darel Wee Kiat Toh Amanda Simin Fu Kervyn Ajay Mehta Nicole Yi Lin Lam Sumanto Haldar Christiani Jeyakumar Henry Source Type: research

Proportions of trans fatty acids in erythrocyte of Canadian adults before the prohibition of partially hydrogenated oils in foods: Results from the Canadian Health Measures Survey 2012-2015
CONCLUSIONS: Pre-PHO prohibition in food in Canada, t-TFA proportions were relatively low compared with a proposed threshold of 1% of total RBC fatty acids over which cardiovascular risk may be higher. Previous voluntary initiatives to reduce i-TFA in the food supply may explain these relatively low RBC t-TFA levels. Some population subgroups had higher baseline RBC TFA than other subgroups, but the physiological implications of these small differences, at relatively low baseline RBC TFA proportions, remain to be determined.CLINICAL TRIAL REGISTRY NUMBER: Not applicable REGISTRY AND REGISTRY NUMBER FOR SYSTEMATIC REVIEWS O...
Source: The American Journal of Clinical Nutrition - April 7, 2024 Category: Nutrition Authors: Isabelle Demonty Loan Nguyen Amanda J MacFarlane Iwona Rudkowska Rana Zoka Kathryn E Hopperton Source Type: research

Proportions of trans fatty acids in erythrocyte of Canadian adults before the prohibition of partially hydrogenated oils in foods: Results from the Canadian Health Measures Survey 2012-2015
CONCLUSIONS: Pre-PHO prohibition in food in Canada, t-TFA proportions were relatively low compared with a proposed threshold of 1% of total RBC fatty acids over which cardiovascular risk may be higher. Previous voluntary initiatives to reduce i-TFA in the food supply may explain these relatively low RBC t-TFA levels. Some population subgroups had higher baseline RBC TFA than other subgroups, but the physiological implications of these small differences, at relatively low baseline RBC TFA proportions, remain to be determined.CLINICAL TRIAL REGISTRY NUMBER: Not applicable REGISTRY AND REGISTRY NUMBER FOR SYSTEMATIC REVIEWS O...
Source: The American Journal of Clinical Nutrition - April 7, 2024 Category: Nutrition Authors: Isabelle Demonty Loan Nguyen Amanda J MacFarlane Iwona Rudkowska Rana Zoka Kathryn E Hopperton Source Type: research

Proportions of trans fatty acids in erythrocyte of Canadian adults before the prohibition of partially hydrogenated oils in foods: Results from the Canadian Health Measures Survey 2012-2015
CONCLUSIONS: Pre-PHO prohibition in food in Canada, t-TFA proportions were relatively low compared with a proposed threshold of 1% of total RBC fatty acids over which cardiovascular risk may be higher. Previous voluntary initiatives to reduce i-TFA in the food supply may explain these relatively low RBC t-TFA levels. Some population subgroups had higher baseline RBC TFA than other subgroups, but the physiological implications of these small differences, at relatively low baseline RBC TFA proportions, remain to be determined.CLINICAL TRIAL REGISTRY NUMBER: Not applicable REGISTRY AND REGISTRY NUMBER FOR SYSTEMATIC REVIEWS O...
Source: The American Journal of Clinical Nutrition - April 7, 2024 Category: Nutrition Authors: Isabelle Demonty Loan Nguyen Amanda J MacFarlane Iwona Rudkowska Rana Zoka Kathryn E Hopperton Source Type: research

Parenteral n-3 polyunsaturated fatty acids supplementation improves postoperative recovery for patients with Crohn's disease after bowel resection: a randomized, unblinded controlled clinical trial
CONCLUSIONS: Parenteral n-3 polyunsaturated fatty acids supplementation promotes postoperative recovery in patients with Crohn's disease following bowel resection, with fewer complications and reduced inflammatory cytokines. This trial was registered at clinicaltrials.gov as NCT03901937 at https://classic.CLINICALTRIALS: gov/ct2/show/NCT03901937?term=NCT03901937&cond=Crohn+Disease&draw=2&rank=1.PMID:38569774 | DOI:10.1016/j.ajcnut.2023.12.022 (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - April 3, 2024 Category: Nutrition Authors: Xiaolong Ge Huaying Liu Yan Wu Wei Liu Weilin Qi Linna Ye Qian Cao Haifeng Lian Rongpan Bai Wei Zhou Source Type: research