Ultrasound enhances the therapeutic potential of mesenchymal stem cells wrapped in greater omentum for aristolochic acid nephropathy
Mesenchymal stem cells (MSCs) have been reported to promote regeneration in both subjects with acute kidney injury (AKI) and chronic kidney disease (CKD), but their efficacy remains limited, probably because m... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - May 3, 2021 Category: Stem Cells Authors: Yuanjun Yang, Xiaodong Geng, Kun Chi, Chao Liu, Ran Liu, Xiangmei Chen, Quan Hong and Guangyan Cai Tags: Research Source Type: research
TRPC7 regulates the electrophysiological functions of embryonic stem cell-derived cardiomyocytes
Biological pacemakers consisting of pluripotent stem cell-derived cardiomyocytes are potentially useful for treating bradycardia. However, tachyarrhythmia caused by derived cardiomyocytes themselves is one of ... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - May 3, 2021 Category: Stem Cells Authors: Xianji Liu, Rui Zhao, Qianqian Ding, Xiaoqiang Yao and Suk Ying Tsang Tags: Research Source Type: research
Small extracellular vesicles from human adipose-derived mesenchymal stromal cells: a potential promoter of fat graft survival
In this study, our purpose is to explore the characteristics of the small ex... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - May 3, 2021 Category: Stem Cells Authors: Aizhen Chen, Shijie Tang, Jiawei He, Xiangyu Li, Guohao Peng, Haoruo Zhang, Jinghua Chen, Liangwan Chen and Xiaosong Chen Tags: Research Source Type: research
Upregulating CXCR7 accelerates endothelial progenitor cell-mediated endothelial repair by activating Akt/Keap-1/Nrf2 signaling in diabetes mellitus
Endothelial progenitor cell (EPC) dysfunction contributes to vascular disease in diabetes mellitus. However, the molecular mechanism underlying EPC dysfunction and its contribution to delayed reendothelializat... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - May 3, 2021 Category: Stem Cells Authors: Chunyu Jiang, Ruiting Li, Chaoyang Xiu, Xu Ma, Hui Hu, Liming Wei, Yihan Tang, Mingyang Tao and Jungong Zhao Tags: Research Source Type: research
Combined topical and systemic administration with human adipose-derived mesenchymal stem cells (hADSC) and hADSC-derived exosomes markedly promoted cutaneous wound healing and regeneration
Cutaneous wound healing and regeneration have become a recognized health challenge in the world, which causes severe damage to the mental and physical health of patients. Human adipose-derived mesenchymal stem... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - May 1, 2021 Category: Stem Cells Authors: Yang Zhou, Bo Zhao, Xin-Liao Zhang, Yi-jun Lu, Shou-Tao Lu, Jian Cheng, Yu Fu, Lin Lin, Ning-Yan Zhang, Pei-Xin Li, Jing Zhang and Jun Zhang Tags: Research Source Type: research
Consecutive daily administration of intratracheal surfactant and human umbilical cord-derived mesenchymal stem cells attenuates hyperoxia-induced lung injury in neonatal rats
Surfactant therapy is a standard of care for preterm infants with respiratory distress and reduces the incidence of death and bronchopulmonary dysplasia in these patients. Our previous study found that mesench... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - May 1, 2021 Category: Stem Cells Authors: Hsiu-Chu Chou, Chien-Hsiang Chang, Chien-Han Chen, Willie Lin and Chung-Ming Chen Tags: Research Source Type: research
Clinical outcomes of modified simple limbal epithelial transplantation for limbal stem cell deficiency in Chinese population: a retrospective case series
To report the clinical outcomes of a novel surgical technique, namely simple limbal epithelial transplantation (SLET), for the treatment of limbal stem cell deficiency (LSCD). (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - May 1, 2021 Category: Stem Cells Authors: Yinghui Wang, Xiaodan Hu, Ke Yang, Yang Zhang, Shijing Deng, Zhiqun Wang, Shang Li, Lei Tian and Ying Jie Tags: Research Source Type: research
Clinical-grade human dental pulp stem cells suppressed the activation of osteoarthritic macrophages and attenuated cartilaginous damage in a rabbit osteoarthritis model
Although increasing evidence has demonstrated that human dental pulp stem cells (hDPSCs) are efficacious for the clinical treatment of skeletal disorders, the underlying mechanisms remain incompletely understo... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - May 1, 2021 Category: Stem Cells Authors: Pei-Lin Li, Yu-Xing Wang, Zhi-Dong Zhao, Zhi-Ling Li, Jia-Wu Liang, Qian Wang, Bo-Feng Yin, Rui-Cong Hao, Meng-Yue Han, Li Ding, Chu-Tse Wu and Heng Zhu Tags: Research Source Type: research
Correction to: Skin regeneration is accelerated by a lower dose of multipotent mesenchymal stromal/ stem cells —a paradigm change
(Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - April 30, 2021 Category: Stem Cells Authors: Gertraud Eylert, Reinhard Dolp, Alexandra Parousis, Richard Cheng, Christopher Auger, Magdalena Holter, Ingrid Lang-Olip, Viola Reiner, Lars-Peter Kamolz and Marc G. Jeschke Tags: Correction Source Type: research
Human acellular amniotic membrane incorporating exosomes from adipose-derived mesenchymal stem cells promotes diabetic wound healing
Diabetic wounds threaten the health and quality of life of patients and their treatment remains challenging. ADSC-derived exosomes have shown encouraging results in enhancing diabetic wound healing. However, h... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - April 29, 2021 Category: Stem Cells Authors: Shune Xiao, Chunfang Xiao, Yong Miao, Jin Wang, Ruosi Chen, Zhexiang Fan and Zhiqi Hu Tags: Research Source Type: research
Different phenotypes and chondrogenic responses of human menstrual blood and bone marrow mesenchymal stem cells to activin A and TGF- β3
Due to its low capacity for self-repair, articular cartilage is highly susceptible to damage and deterioration, which leads to the development of degenerative joint diseases such as osteoarthritis (OA). Menstr... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - April 29, 2021 Category: Stem Cells Authors: Ilona Uzieliene, Edvardas Bagdonas, Kazuto Hoshi, Tomoaki Sakamoto, Atsuhiko Hikita, Zivile Tachtamisevaite, Greta Rakauskiene, Giedrius Kvederas, Ali Mobasheri and Eiva Bernotiene Tags: Research Source Type: research
Curcumin-primed human BMSC-derived extracellular vesicles reverse IL-1 β-induced catabolic responses of OA chondrocytes by upregulating miR-126-3p
Curcumin has anti-inflammatory effects and qualifies as a potential candidate for the treatment of osteoarthritis (OA). However, curcumin has limited bioavailability. Extracellular vesicles (EVs) are released ... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - April 29, 2021 Category: Stem Cells Authors: Shushan Li, Sabine St öckl, Christoph Lukas, Marietta Herrmann, Christoph Brochhausen, Matthias A. König, Brian Johnstone and Susanne Grässel Tags: Research Source Type: research
Towards physiologically relevant human pluripotent stem cell (hPSC) models of Parkinson ’s disease
The derivation of human embryonic stem cells followed by the discovery of induced pluripotent stem cells and leaps in genome editing approaches have continuously fueled enthusiasm for the development of new mo... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - April 29, 2021 Category: Stem Cells Authors: Elena Coccia and Tim Ahfeldt Tags: Review Source Type: research
Melatonin induces the rejuvenation of long-term ex vivo expanded periodontal ligament stem cells by modulating the autophagic process
Stem cells that have undergone long-term ex vivo expansion are most likely functionally compromised (namely cellular senescence) in terms of their stem cell properties and therapeutic potential. Due to its abi... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - April 29, 2021 Category: Stem Cells Authors: Yi-Zhou Tan, Xin-Yue Xu, Ji-Min Dai, Yuan Yin, Xiao-Tao He, Yi-Lin Zhang, Tian-Xiao Zhu, Ying An, Bei-Min Tian and Fa-Ming Chen Tags: Research Source Type: research
Correction to: Treating primary immunodeficiencies with defects in NK cells: from stem cell therapy to gene editing
An amendment to this paper has been published and can be accessed via the original article. (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - April 27, 2021 Category: Stem Cells Authors: C. Eguizabal, L. Herrera, M. Ingl és-Ferrándiz and J. C. Izpisua Belmonte Tags: Correction Source Type: research
