Signal Transduction Knowledge Environment 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.The Helicobacter pylori CagA oncoprotein disrupts Wnt/PCP signaling and promotes hyperproliferation of pyloric gland base cells | Science Signaling
An H. pylori oncoprotein induces stomach epithelial hyperplasia by impairing planar cell polarity signaling. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - July 18, 2023 Category: Science Source Type: news
ERK2 stimulates MYC transcription by anchoring CDK9 to the MYC promoter in a kinase activity –independent manner | Science Signaling
ERK2 enhances the expression of an oncogene by tethering the kinase CDK9 to the oncogene ’s promoter. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - July 18, 2023 Category: Science Source Type: news
Exploiting an epigenetic switch in adrenal cancer | Science Signaling
EZH2 inhibitors may slow the progression of an aggressive form of adrenocortical cancer. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - July 18, 2023 Category: Science Source Type: news
TRPM7 kinase activity induces amyloid- β degradation to reverse synaptic and cognitive deficits in mouse models of Alzheimer’s disease | Science Signaling
Loss of the kinase activity of TRPM7 may contribute to amyloid pathology in Alzheimer ’s disease. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - July 11, 2023 Category: Science Source Type: news
Skewing cPLA2 α activity toward oxoeicosanoid production promotes neutrophil N2 polarization, wound healing, and the response to sepsis | Science Signaling
Eicosanoid biosynthesis influences neutrophil polarization in wound healing and sepsis. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - July 11, 2023 Category: Science Source Type: news
Bias comes in layers | Science Signaling
GINIP promotes G βγ signaling while inhibiting Gαi signaling to fine-tune GPCR-mediated neuromodulation. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - July 11, 2023 Category: Science Source Type: news
Centralspindlin-mediated transport of RhoGEF positions the cleavage plane for cytokinesis | Science Signaling
RhoGEF piggybacks on microtubule motor proteins to activate cell division along the cell ’s equator. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - July 4, 2023 Category: Science Source Type: news
Clustering of phosphatase RPTP α promotes Src signaling and the arthritogenic action of synovial fibroblasts | Science Signaling
Blocking the clustering of the phosphatase RPTP α limits signaling that leads to arthritic joint damage. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - July 4, 2023 Category: Science Source Type: news
Extracellular messaging elicited by exercise | Science Signaling
The exercise-induced secretomes of multiple cell types in mice are characterized. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - July 4, 2023 Category: Science Source Type: news
The transcription factor XBP1 in dendritic cells promotes the TH2 cell response in airway allergy | Science Signaling
Allergens stimulate the expression of XBP1 in dendritic cells to promote TH2 cell –dependent allergic responses. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - June 27, 2023 Category: Science Source Type: news
IKK promotes na ïve T cell survival by repressing RIPK1-dependent apoptosis and activating NF-κB | Science Signaling
Na ïve mouse T cell homeostasis requires both IKK-mediated inhibition of death and activation of survival pathways. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - June 27, 2023 Category: Science Source Type: news
Eliminating infection by promoting bacterial growth | Science Signaling
Host reactive nitrogen species maintain intracellular Salmonella in an antibiotic-tolerant, persister state. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - June 27, 2023 Category: Science Source Type: news
cAMPing up cancer immunotherapy | Science Signaling
Adrenergic receptor stimulation improves cancer immunotherapy in a range of immune-competent tumor models. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - June 20, 2023 Category: Science Source Type: news
Adhesion to laminin-1 and collagen IV induces the formation of Ca2+ microdomains that sensitize mouse T cells for activation | Science Signaling
Ca2+ signaling triggered by adhesion to specific extracellular matrix proteins facilitates T cell activation. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - June 20, 2023 Category: Science Source Type: news
The lncRNA LETS1 promotes TGF- β–induced EMT and cancer cell migration by transcriptionally activating a TβR1-stabilizing mechanism | Science Signaling
A TGF- β–induced lncRNA potentiates TGF-β signaling by inhibiting ubiquitination of the TGF-β type I receptor. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - June 20, 2023 Category: Science Source Type: news
