Signal Transduction Knowledge Environment 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Sleep and longevity tied to glia | Science Signaling
Glia mediate two-way signaling between the brain and gut that supports sleep and healthy aging. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - October 31, 2023 Category: Science Source Type: news
Purinergic P2Y2 receptor –induced activation of endothelial TRPV4 channels mediates lung ischemia-reperfusion injury | Science Signaling
How TRPV4 is activated to result in the pathological sequelae of lung ischemia/reperfusion injury is revealed. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - October 24, 2023 Category: Science Source Type: news
Human IL-17A protein production is controlled through a PIP5K1 α-dependent translational checkpoint | Science Signaling
Nuclear enrichment of the phospholipid PIP2 facilitates interleukin-17 translation by CD4+ helper T cells. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - October 24, 2023 Category: Science Source Type: news
Binding of CaMKII to the NMDA receptor is sufficient for long-term potentiation | Science Signaling
CaMKII can induce potentiation of glutamatergic synapses purely by binding to postsynaptic proteins. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - October 24, 2023 Category: Science Source Type: news
Restraining neuroinflammation in Alzheimer ’s disease | Science Signaling
CD8+ T cells recruited to the brain in a mouse model of Alzheimer's disease limit disease pathology. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - October 24, 2023 Category: Science Source Type: news
Phosphatidic acid binding to Patched contributes to the inhibition of Smoothened and Hedgehog signaling in Drosophila wing development | Science Signaling
The Hedgehog receptor Patched inhibits Smoothened in part by sequestering phosphatidic acid. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - October 17, 2023 Category: Science Source Type: news
Multivalent, asymmetric IL-2 –Fc fusions show enhanced selectivity for regulatory T cells | Science Signaling
Engineering an α chain–biased, multivalent IL-2 may improve its utility in treating autoimmunity. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - October 17, 2023 Category: Science Source Type: news
The long-lasting effects of NO | Science Signaling
A stable adduct of the gasotransmitter NO that can induce vasodilation is characterized. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - October 17, 2023 Category: Science Source Type: news
TRIM55 promotes noncanonical NF- κB signaling and B cell–mediated immune responses by coordinating p100 ubiquitination and processing | Science Signaling
Noncanonical NF- κB signaling underlying B cell–dependent immunity and autoimmunity requires the E3 ubiquitin ligase TRIM55. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - October 10, 2023 Category: Science Source Type: news
Membrane-proximal motifs encode differences in signaling strength between type I and III interferon receptors | Science Signaling
An intracellular motif in type I interferon receptors ensures they signal more strongly than their type III counterparts. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - October 10, 2023 Category: Science Source Type: news
Neural control of gut repair | Science Signaling
Intestinal injury induces the outgrowth of adrenergic neurons that stimulate a proregenerative pathway. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - October 10, 2023 Category: Science Source Type: news
Signaling dynamics distinguish high- and low-priority neutrophil chemoattractant receptors | Science Signaling
Neutrophils prioritize chemoattractant inputs according to the duration of the signaling output. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - October 3, 2023 Category: Science Source Type: news
The ligand-dependent suppression of TCR signaling by the immune checkpoint receptor LAG3 depends on the cytoplasmic RRFSALE motif | Science Signaling
A cytoplasmic motif in LAG3 mediates ligand-dependent inhibition of T cell receptor signaling. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - October 3, 2023 Category: Science Source Type: news
Stress exhausts T cells | Science Signaling
Catecholamines associated with stress promote T cell exhaustion through the β1-adrenergic receptor. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - October 3, 2023 Category: Science Source Type: news
Transcriptomics-inferred dynamics of SARS-CoV-2 interactions with host epithelial cells | Science Signaling
The timing of transcriptional events in SARS-CoV-2 –infected cells reveals a host-targeted treatment. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - September 26, 2023 Category: Science Source Type: news
