Signal Transduction Knowledge Environment 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Palmitoylation of the Parkinson ’s disease–associated protein synaptotagmin-11 links its turnover to α-synuclein homeostasis | Science Signaling
Palmitoylation of synaptotagmin-11 supports the assembly of aggregation-prone α-synuclein monomers in neurons. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - February 14, 2023 Category: Science Source Type: news
The fragile state of opioid withdrawal | Science Signaling
Fragile Treg cells induced by opioid usage cause synaptic weakening and withdrawal symptoms. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - February 14, 2023 Category: Science Source Type: news
USP47 deubiquitylates Groucho/TLE to promote Wnt –β-catenin signaling | Science Signaling
The deubiquitylase USP47 enables the corepressor TLE to reassociate with promoters of Wnt target genes. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - February 7, 2023 Category: Science Source Type: news
A single amino acid deletion in the ER Ca2+ sensor STIM1 reverses the in vitro and in vivo effects of the Stormorken syndrome –causing R304W mutation | Science Signaling
Disrupted intramolecular contacts underlie the effects of a disease-associated STIM1 mutant in cells and mice. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - February 7, 2023 Category: Science Source Type: news
Pathogen-associated grooming | Science Signaling
A fungal surface protein elicits grooming in flies. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - February 7, 2023 Category: Science Source Type: news
Deciphering functional roles and interplay between Beclin1 and Beclin2 in autophagosome formation and mitophagy | Science Signaling
The contributions of Beclin1 and Beclin2 to basal and stress-induced autophagy and mitophagy are defined. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - January 31, 2023 Category: Science Source Type: news
The dual-function chemokine receptor CCR2 drives migration and chemokine scavenging through distinct mechanisms | Science Signaling
Proteins involved in chemokine signaling mediated by CCR2 are not required for its scavenging function. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - January 31, 2023 Category: Science Source Type: news
Folding the neural plate | Science Signaling
Apical constriction and neural tube closure depend on coordinated ephrin and Wnt signaling. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - January 31, 2023 Category: Science Source Type: news
An allosteric switch ensures efficient unidirectional information transmission by the histidine kinase DesK from Bacillus subtilis | Science Signaling
Structural and kinetic factors ensure unidirectional information flow in a bacterial two-component system. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - January 24, 2023 Category: Science Source Type: news
NET formation is independent of gasdermin D and pyroptotic cell death | Science Signaling
The formation of neutrophil extracellular traps requires neither cell death nor the pore-forming protein gasdermin D. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - January 24, 2023 Category: Science Source Type: news
Poking holes in pyroptosis paradigms | Science Signaling
Several studies show that there is still much to learn about cell death mechanisms. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - January 24, 2023 Category: Science Source Type: news
A hepatokine derived from the ER protein CREBH promotes triglyceride metabolism by stimulating lipoprotein lipase activity | Science Signaling
Fasting or hepatic stress induces the release of a hepatokine that enhances triglyceride lipolysis and clearance. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - January 17, 2023 Category: Science Source Type: news
Tyrosine kinase inhibitors can activate the NLRP3 inflammasome in myeloid cells through lysosomal damage and cell lysis | Science Signaling
Unintended damage to myeloid cells may promote the efficacy or toxicity of tyrosine kinase inhibitors. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - January 17, 2023 Category: Science Source Type: news
A check on the immunological synapse | Science Signaling
Blocking Nogo receptor 1 on natural killer cells enhances cell killing by stabilizing contact with target cells. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - January 17, 2023 Category: Science Source Type: news
The phosphate-induced small RNA EsrL promotes E. coli virulence, biofilm formation, and intestinal colonization | Science Signaling
A small RNA enhances E. coli pathogenicity in phosphate-rich conditions such as the gut. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - January 10, 2023 Category: Science Source Type: news
