Signal Transduction Knowledge Environment 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Oct1 cooperates with the Smad family of transcription factors to promote mesodermal lineage specification | Science Signaling
Oct1 enforces mesoderm-specific gene expression by cooperating with the Smad family of transcription factors. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - April 18, 2023 Category: Science Source Type: news
The proliferation of human mucosal-associated invariant T cells requires a MYC-SLC7A5-glycolysis metabolic axis | Science Signaling
Innate-like T cell metabolism is controlled by MYC and impaired during obesity. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - April 18, 2023 Category: Science Source Type: news
Goblet cell stress management | Science Signaling
Autophagy augments the mucus-secreting capacity of goblet cells by reducing ER stress. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - April 18, 2023 Category: Science Source Type: news
Metastatic dormancy needs STING | Science Signaling
STING activity in cancer cells prevents the progression of dormant metastasis. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - April 11, 2023 Category: Science Source Type: news
HSP90 inhibition in the mouse spinal cord enhances opioid signaling by suppressing an AMPK-mediated negative feedback loop | Science Signaling
The activity of the chaperone HSP90 and the kinase AMPK in the spine limits opioid efficacy. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - April 11, 2023 Category: Science Source Type: news
SHP-1 localization to the activating immune synapse promotes NK cell tolerance in MHC class I deficiency | Science Signaling
The spatial patterning of the tyrosine phosphatase SHP-1 in mouse NK cells may determine self-tolerance. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - April 11, 2023 Category: Science Source Type: news
WNT stimulation induces dynamic conformational changes in the Frizzled-Dishevelled interaction | Science Signaling
WNT binding triggers rearrangements in a receptor-effector complex that may affect downstream signaling. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - April 4, 2023 Category: Science Source Type: news
Migration mediated by the oxysterol receptor GPR183 depends on arrestin coupling but not receptor internalization | Science Signaling
The interaction of the GPCR GPR183 with β-arrestins rather than receptor internalization drives chemotactic function. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - April 4, 2023 Category: Science Source Type: news
Light sleeper? Eat more protein | Science Signaling
A high-protein diet may promote deep sleep by gut secretion of a dopamine neuron –stimulating peptide. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - April 4, 2023 Category: Science Source Type: news
Blockade of ROS production inhibits oncogenic signaling in acute myeloid leukemia and amplifies response to precision therapies | Science Signaling
Inhibiting the ROS-generating Rac-NOX2 complex delays the progression of FLT3 mutant acute myeloid leukemia. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - March 28, 2023 Category: Science Source Type: news
Arrestin-dependent nuclear export of phosphodiesterase 4D promotes GPCR-induced nuclear cAMP signaling required for learning and memory | Science Signaling
β2-adrenoceptor activation stimulates the nuclear export of PDE4D5 to promote learning and memory. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - March 28, 2023 Category: Science Source Type: news
A boost in learning by removing nuclear phosphodiesterases and enhancing nuclear cAMP signaling | Science Signaling
Nuclear cAMP signaling underlying learning and memory is boosted by nuclear phosphodiesterase removal (Martinez et al., in 28 March 2023 issue). (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - March 28, 2023 Category: Science Source Type: news
Blebby survivors | Science Signaling
Membrane blebs form signaling hubs that enable tumor cells to resist death by anoikis. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - March 28, 2023 Category: Science Source Type: news
The adrenal stress response is an essential host response against therapy-induced lethal immune activation | Science Signaling
Prophylactic glucocorticoids might dampen immunotherapy-induced cytokine storm in some patients. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - March 21, 2023 Category: Science Source Type: news
Hedgehog-induced ZFYVE21 promotes chronic vascular inflammation by activating NLRP3 inflammasomes in T cells | Science Signaling
Endothelial SHH promotes T cell –mediated inflammation in allograft vasculopathy. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - March 21, 2023 Category: Science Source Type: news
