Guanidinium-based Integrated Peptide Dendrimers: Pioneer Nanocarrier in Cancer Therapy
Protein Pept Lett. 2024 Apr 16. doi: 10.2174/0109298665292042240325052536. Online ahead of print.ABSTRACTThe landscape of cancer therapy has witnessed a paradigm shift with the emergence of innovative delivery systems, and Guanidinium-based Peptide Dendrimers have emerged as a vanguard in this transformative journey. With their unique molecular architecture and intrinsic biocompatibility, these dendrimers offer a promising avenue for the targeted delivery of therapeutic cargo in cancer treatment. This comprehensive review delves into the intricate world of Guanidinium- based Peptide Dendrimers, unraveling their structural ...
Source: Protein and Peptide Letters - April 17, 2024 Category: Biochemistry Authors: Dilpreet Singh Lalu Muhammad Irham Amrinder Singh Balak Das Kurmi Source Type: research

Unveiling the Molecular Mechanism of Diosmetin and its Impact on Multifaceted Cellular Signaling Pathways
CONCLUSION: The amalgamation of the review underscores diosmetin's promising role as a multifaceted therapeutic agent, highlighting its potential for drug development and clinical applications.PMID:38629379 | DOI:10.2174/0109298665294109240323033601 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - April 17, 2024 Category: Biochemistry Authors: Krishna Kumar Varshney Jeetendra Kumar Gupta Rajnish Srivastava Source Type: research

Guanidinium-based Integrated Peptide Dendrimers: Pioneer Nanocarrier in Cancer Therapy
Protein Pept Lett. 2024 Apr 16. doi: 10.2174/0109298665292042240325052536. Online ahead of print.ABSTRACTThe landscape of cancer therapy has witnessed a paradigm shift with the emergence of innovative delivery systems, and Guanidinium-based Peptide Dendrimers have emerged as a vanguard in this transformative journey. With their unique molecular architecture and intrinsic biocompatibility, these dendrimers offer a promising avenue for the targeted delivery of therapeutic cargo in cancer treatment. This comprehensive review delves into the intricate world of Guanidinium- based Peptide Dendrimers, unraveling their structural ...
Source: Protein and Peptide Letters - April 17, 2024 Category: Biochemistry Authors: Dilpreet Singh Lalu Muhammad Irham Amrinder Singh Balak Das Kurmi Source Type: research

Unveiling the Molecular Mechanism of Diosmetin and its Impact on Multifaceted Cellular Signaling Pathways
CONCLUSION: The amalgamation of the review underscores diosmetin's promising role as a multifaceted therapeutic agent, highlighting its potential for drug development and clinical applications.PMID:38629379 | DOI:10.2174/0109298665294109240323033601 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - April 17, 2024 Category: Biochemistry Authors: Krishna Kumar Varshney Jeetendra Kumar Gupta Rajnish Srivastava Source Type: research

Enhancement of Oral Bioavailability of Protein and Peptide by Polysaccharide-based Nanoparticles
Protein Pept Lett. 2024 Mar 20. doi: 10.2174/0109298665292469240228064739. Online ahead of print.ABSTRACTOral drug delivery is a prevalent and cost-effective method due to its advantages, such as increased drug absorption surface area and improved patient compliance. However, delivering proteins and peptides orally remains a challenge due to their vulnerability to degradation by digestive enzymes, stomach acids, and limited intestinal membrane permeability, resulting in poor bioavailability. The use of nanotechnology has emerged as a promising solution to enhance the bioavailability of these vital therapeutic agents. Polym...
Source: Protein and Peptide Letters - March 21, 2024 Category: Biochemistry Authors: Md Moidul Islam Sarjana Raikwar Source Type: research

Enhancement of Oral Bioavailability of Protein and Peptide by Polysaccharide-based Nanoparticles
Protein Pept Lett. 2024 Mar 20. doi: 10.2174/0109298665292469240228064739. Online ahead of print.ABSTRACTOral drug delivery is a prevalent and cost-effective method due to its advantages, such as increased drug absorption surface area and improved patient compliance. However, delivering proteins and peptides orally remains a challenge due to their vulnerability to degradation by digestive enzymes, stomach acids, and limited intestinal membrane permeability, resulting in poor bioavailability. The use of nanotechnology has emerged as a promising solution to enhance the bioavailability of these vital therapeutic agents. Polym...
Source: Protein and Peptide Letters - March 21, 2024 Category: Biochemistry Authors: Md Moidul Islam Sarjana Raikwar Source Type: research

Enhancement of Oral Bioavailability of Protein and Peptide by Polysaccharide-based Nanoparticles
Protein Pept Lett. 2024 Mar 20. doi: 10.2174/0109298665292469240228064739. Online ahead of print.ABSTRACTOral drug delivery is a prevalent and cost-effective method due to its advantages, such as increased drug absorption surface area and improved patient compliance. However, delivering proteins and peptides orally remains a challenge due to their vulnerability to degradation by digestive enzymes, stomach acids, and limited intestinal membrane permeability, resulting in poor bioavailability. The use of nanotechnology has emerged as a promising solution to enhance the bioavailability of these vital therapeutic agents. Polym...
Source: Protein and Peptide Letters - March 21, 2024 Category: Biochemistry Authors: Md Moidul Islam Sarjana Raikwar Source Type: research

Enhancement of Oral Bioavailability of Protein and Peptide by Polysaccharide-based Nanoparticles
Protein Pept Lett. 2024 Mar 20. doi: 10.2174/0109298665292469240228064739. Online ahead of print.ABSTRACTOral drug delivery is a prevalent and cost-effective method due to its advantages, such as increased drug absorption surface area and improved patient compliance. However, delivering proteins and peptides orally remains a challenge due to their vulnerability to degradation by digestive enzymes, stomach acids, and limited intestinal membrane permeability, resulting in poor bioavailability. The use of nanotechnology has emerged as a promising solution to enhance the bioavailability of these vital therapeutic agents. Polym...
Source: Protein and Peptide Letters - March 21, 2024 Category: Biochemistry Authors: Md Moidul Islam Sarjana Raikwar Source Type: research

Enhancement of Oral Bioavailability of Protein and Peptide by Polysaccharide-based Nanoparticles
Protein Pept Lett. 2024 Mar 20. doi: 10.2174/0109298665292469240228064739. Online ahead of print.ABSTRACTOral drug delivery is a prevalent and cost-effective method due to its advantages, such as increased drug absorption surface area and improved patient compliance. However, delivering proteins and peptides orally remains a challenge due to their vulnerability to degradation by digestive enzymes, stomach acids, and limited intestinal membrane permeability, resulting in poor bioavailability. The use of nanotechnology has emerged as a promising solution to enhance the bioavailability of these vital therapeutic agents. Polym...
Source: Protein and Peptide Letters - March 21, 2024 Category: Biochemistry Authors: Md Moidul Islam Sarjana Raikwar Source Type: research

Enhancement of Oral Bioavailability of Protein and Peptide by Polysaccharide-based Nanoparticles
Protein Pept Lett. 2024 Mar 20. doi: 10.2174/0109298665292469240228064739. Online ahead of print.ABSTRACTOral drug delivery is a prevalent and cost-effective method due to its advantages, such as increased drug absorption surface area and improved patient compliance. However, delivering proteins and peptides orally remains a challenge due to their vulnerability to degradation by digestive enzymes, stomach acids, and limited intestinal membrane permeability, resulting in poor bioavailability. The use of nanotechnology has emerged as a promising solution to enhance the bioavailability of these vital therapeutic agents. Polym...
Source: Protein and Peptide Letters - March 21, 2024 Category: Biochemistry Authors: Md Moidul Islam Sarjana Raikwar Source Type: research

Enhancement of Oral Bioavailability of Protein and Peptide by Polysaccharide-based Nanoparticles
Protein Pept Lett. 2024 Mar 20. doi: 10.2174/0109298665292469240228064739. Online ahead of print.ABSTRACTOral drug delivery is a prevalent and cost-effective method due to its advantages, such as increased drug absorption surface area and improved patient compliance. However, delivering proteins and peptides orally remains a challenge due to their vulnerability to degradation by digestive enzymes, stomach acids, and limited intestinal membrane permeability, resulting in poor bioavailability. The use of nanotechnology has emerged as a promising solution to enhance the bioavailability of these vital therapeutic agents. Polym...
Source: Protein and Peptide Letters - March 21, 2024 Category: Biochemistry Authors: Md Moidul Islam Sarjana Raikwar Source Type: research

Enhancement of Oral Bioavailability of Protein and Peptide by Polysaccharide-based Nanoparticles
Protein Pept Lett. 2024 Mar 20. doi: 10.2174/0109298665292469240228064739. Online ahead of print.ABSTRACTOral drug delivery is a prevalent and cost-effective method due to its advantages, such as increased drug absorption surface area and improved patient compliance. However, delivering proteins and peptides orally remains a challenge due to their vulnerability to degradation by digestive enzymes, stomach acids, and limited intestinal membrane permeability, resulting in poor bioavailability. The use of nanotechnology has emerged as a promising solution to enhance the bioavailability of these vital therapeutic agents. Polym...
Source: Protein and Peptide Letters - March 21, 2024 Category: Biochemistry Authors: Md Moidul Islam Sarjana Raikwar Source Type: research

Enhancement of Oral Bioavailability of Protein and Peptide by Polysaccharide-based Nanoparticles
Protein Pept Lett. 2024 Mar 20. doi: 10.2174/0109298665292469240228064739. Online ahead of print.ABSTRACTOral drug delivery is a prevalent and cost-effective method due to its advantages, such as increased drug absorption surface area and improved patient compliance. However, delivering proteins and peptides orally remains a challenge due to their vulnerability to degradation by digestive enzymes, stomach acids, and limited intestinal membrane permeability, resulting in poor bioavailability. The use of nanotechnology has emerged as a promising solution to enhance the bioavailability of these vital therapeutic agents. Polym...
Source: Protein and Peptide Letters - March 21, 2024 Category: Biochemistry Authors: Md Moidul Islam Sarjana Raikwar Source Type: research

Enhancement of Oral Bioavailability of Protein and Peptide by Polysaccharide-based Nanoparticles
Protein Pept Lett. 2024 Mar 20. doi: 10.2174/0109298665292469240228064739. Online ahead of print.ABSTRACTOral drug delivery is a prevalent and cost-effective method due to its advantages, such as increased drug absorption surface area and improved patient compliance. However, delivering proteins and peptides orally remains a challenge due to their vulnerability to degradation by digestive enzymes, stomach acids, and limited intestinal membrane permeability, resulting in poor bioavailability. The use of nanotechnology has emerged as a promising solution to enhance the bioavailability of these vital therapeutic agents. Polym...
Source: Protein and Peptide Letters - March 21, 2024 Category: Biochemistry Authors: Md Moidul Islam Sarjana Raikwar Source Type: research

Enhancement of Oral Bioavailability of Protein and Peptide by Polysaccharide-based Nanoparticles
Protein Pept Lett. 2024 Mar 20. doi: 10.2174/0109298665292469240228064739. Online ahead of print.ABSTRACTOral drug delivery is a prevalent and cost-effective method due to its advantages, such as increased drug absorption surface area and improved patient compliance. However, delivering proteins and peptides orally remains a challenge due to their vulnerability to degradation by digestive enzymes, stomach acids, and limited intestinal membrane permeability, resulting in poor bioavailability. The use of nanotechnology has emerged as a promising solution to enhance the bioavailability of these vital therapeutic agents. Polym...
Source: Protein and Peptide Letters - March 21, 2024 Category: Biochemistry Authors: Md Moidul Islam Sarjana Raikwar Source Type: research