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Higher Lead Levels in Childhood Linked to Lower IQ, Socioeconomic Status in Adults (FREE)
By the Editors Greater childhood lead exposure is tied to slightly lower cognitive function and socioeconomic status in adulthood, according to a JAMA study. … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 29, 2017 Category: Primary Care Source Type: news

Vitamin D Supplements Fail to Prevent Cancer in 4-Year Trial (FREE)
By Amy Orciari Herman Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM Supplementation with vitamin D and calcium doesn ' t help prevent cancer in healthy older women, a JAMA study finds.Some 2300 healthy women aged 55 … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 29, 2017 Category: Primary Care Source Type: news

USPSTF Finalizes Recommendation on Celiac Disease Screening (FREE)
By the Editors The U.S. Preventive Services Task Force has concluded that the available evidence is insufficient to recommend for or against screening for celiac disease in asymptomatic … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 29, 2017 Category: Primary Care Source Type: news

Updated Guidelines on Brachytherapy for Prostate Cancer (FREE)
By Joe Elia Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM The American Society of Clinical Oncology and Cancer Care Ontario have issued a joint updated guideline on … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 29, 2017 Category: Primary Care Source Type: news

Niraparib Approved for Maintenance Therapy of Ovarian Cancer (FREE)
By Kristin J. Kelley Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM The FDA has approved niraparib … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 29, 2017 Category: Primary Care Source Type: news

Injectable Dupilumab Approved for Eczema (FREE)
By Kelly Young Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM The FDA has approved dupilumab (Dupixent) to treat moderate-to-severe atopic dermatitis. It is indicated … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 29, 2017 Category: Primary Care Source Type: news

Your NEJM Group Today: Sciatica Management / Antenatal Glucocorticoids for Preterm Birth / Louisiana Emergency Medicine Opportunities (FREE)
By the Editors Here ' s today ' s offering from NEJM Group:NEJM Clinical Practice Center: Clinical decisions: This interactive feature on the management of sciatica offers a case … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 29, 2017 Category: Primary Care Source Type: news

Knee Replacement Should Be Reserved for More Severe Osteoarthritis, Study Suggests (FREE)
By Amy Orciari Herman Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM Total knee replacement for knee osteoarthritis should be reserved for patients with more severe OA symptoms, according to … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 29, 2017 Category: Primary Care Source Type: news

Antibiotics Fail More Often Than Appendectomy for Pediatric Appendicitis (FREE)
By Kelly Young Edited by Jaye Elizabeth Hefner, MD Antibiotics may be effective for pediatric appendicitis, but they have a higher failure rate than appendectomy, particularly in the presence of appendicolith, according to a meta-analysis in JAMA Pediatrics … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 28, 2017 Category: Primary Care Source Type: news

Diabetic Retinopathy Screening: Primary Care-Based Telemedicine Program Shows Promise (FREE)
By Amy Orciari Herman Edited by Jaye Elizabeth Hefner, MD An innovative strategy for diabetic retinopathy screening in primary care could significantly increase screening rates, cut screening wait times, and reduce unnecessary referrals to specialty care, a JAMA Internal … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 28, 2017 Category: Primary Care Source Type: news

Your NEJM Group Today: NEJM Knowledge+ Pediatrics / GI Bleeding with Direct Oral Anticoagulants vs. Warfarin / New Hampshire Family Medicine Opportunity (FREE)
By the Editors Here ' s today ' s offering from NEJM Group:NEJM Knowledge+ Pediatrics: We ' re pleased to announce the launch of NEJM Knowledge+ Pediatrics Board Review. This program … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 28, 2017 Category: Primary Care Source Type: news

Which Drugs Work for Diabetic Peripheral Neuropathy Pain? (FREE)
By Kelly Young Edited by Susan Sadoughi, MD, and Andr é Sofair, MD, MPH Duloxetine, venlafaxine, pregabalin, oxcarbazepine, tricyclic antidepressants, atypical opioids (e.g., tapentadol), and botulinum toxin are all more effective than placebo in reducing … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 27, 2017 Category: Primary Care Source Type: news

From the Blogs: Time for a Better Name for Endocarditis? / When Medicine Is Hard (FREE)
By the Editors Here ' s a quick look at what the NEJM Journal Watch bloggers are talking … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 27, 2017 Category: Primary Care Source Type: news

Obamacare Replacement Pulled (FREE)
By the Editors In case you missed it, House Republicans decided not to put … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 27, 2017 Category: Primary Care Source Type: news

Your NEJM Group Today: Healthcare Needs Data Science Strategy / Low-Cost Rotavirus Vaccine / New York Hematologist-Oncologist Opportunity (FREE)
By the Editors Have a look at today ' s featured articles from NEJM Group:NEJM Catalyst: Data science strategy can help … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 27, 2017 Category: Primary Care Source Type: news

Oral Food Challenge Could Help Better Diagnose Patients with Tree Nut Allergy (FREE)
By Kelly Young Edited by Susan Sadoughi, MD, and Andr é Sofair, MD, MPH Avoiding all tree nuts might not be necessary in people who have a single tree nut allergy, suggests a study in Annals of Allergy, Asthma and Immunology. Researchers analyzed data from over 150 tree nut oral food … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 27, 2017 Category: Primary Care Source Type: news

Most Popular NEJM Group Feature This Week: High-Performing Jerks (FREE)
By the Editors Edited by Andr é Sofair, MD, MPH, and William E. Chavey, … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 24, 2017 Category: Primary Care Source Type: news

Your NEJM Group Today: Benzodiazepine Dependence Review / Newer Diabetes Drugs & Pancreatitis / North Carolina Hospitalist Opportunities (FREE)
By the Editors Here ' s what we chose for you from NEJM Group today:NEJM Clinical Practice Center: Review Article: Long-term use of benzodiazepines can … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 24, 2017 Category: Primary Care Source Type: news

CDC Study Supports TB Screening of Foreign-Born People Regardless of Time Since U.S. Arrival (FREE)
By Cara Adler Edited by Andr é Sofair, MD, MPH, and William E. Chavey, MD, MS Starting in 2013, the number of U.S. tuberculosis diagnoses among foreign-born people was higher in those who had arrived many years before diagnosis than … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 24, 2017 Category: Primary Care Source Type: news

Many Youth Newly Diagnosed with Diabetes Aren ' t Screened for Retinopathy (FREE)
By Kelly Young Edited by Andr é Sofair, MD, MPH, and William E. Chavey, MD, MS Many children and adolescents with diabetes aren ' t being screened for diabetic retinopathy soon after their diagnosis, according to a retrospective study in … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 24, 2017 Category: Primary Care Source Type: news

Pregabalin Doesn ' t Help Sciatica Pain (FREE)
By the Editors Pregabalin (Lyrica) doesn ' t seem to improve sciatica pain, according to a study in the New England Journal of … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 23, 2017 Category: Primary Care Source Type: news

Safinamide Approved as Add-On Treatment for Parkinson ' s Disease (FREE)
By Kristin J. Kelley Edited by Susan Sadoughi, MD The FDA has approved safinamide (marketed as Xadago) for treating increased symptoms of Parkinson disease. The drug is indicated as add-on therapy for patients in whom … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 23, 2017 Category: Primary Care Source Type: news

Your NEJM Group Today: Depression & Suicidality in Medicine / ACC 2017 Meeting Wrap-up / Massachusetts Primary Care Opportunities (FREE)
By the Editors Here ' s today ' s offering from NEJM Group:NEJM Audio Interview: Depression and Suicidality in Medicine: Dr. Stuart Slavin discusses depression and suicide among physicians … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 23, 2017 Category: Primary Care Source Type: news

Obamacare ' s Effects on the Four Most Populous States Show Wide Variation (FREE)
By Joe Elia Edited by Susan Sadoughi, MD A study of the Affordable Care Act ' s effects in California, New York, Florida, and Texas seems to show that Medicaid expansion was associated with better coverage and … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 23, 2017 Category: Primary Care Source Type: news

Alcohol ' s Link to Cardiovascular Disease Not So Simple (FREE)
By Amy Orciari Herman Edited by Susan Sadoughi, MD Moderate alcohol consumption seems associated with lower cardiovascular risks, but the relationship is highly nuanced, a study in The BMJ finds.Researchers linked U.K. primary care, hospital, and mortality records to examine associations between … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 23, 2017 Category: Primary Care Source Type: news

Prenatal DHA Supplementation Offers No Long-Term IQ Benefit in Offspring (FREE)
By the Editors Prenatal docosahexaenoic acid (DHA) supplementation does not lead to improved IQ in school-aged children, according to findings reported … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 21, 2017 Category: Primary Care Source Type: news

FDA Updates Guidance on Breast Implant-Associated Lymphomas (FREE)
By Joe Elia Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM Breast implant-associated anaplastic large cell lymphomas — a rare condition — occur more … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 21, 2017 Category: Primary Care Source Type: news

Your NEJM Group Today: The Case for Supervised Injection Facilities / Contraception Access After Abortion / Colorado Medical Director Opportunity (FREE)
By the Editors Here are today ' s selected readings from NEJM Group:NEJM Clinical Practice Center: Perspective: Many heroin users abstain from use while taking buprenorphine, but the daily decision to take … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 21, 2017 Category: Primary Care Source Type: news

Patient Exposure to Testosterone TV Ads Associated with More Testosterone Testing, Treatment (FREE)
By Amy Orciari Herman Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM Increases in televised direct-to-consumer testosterone ads were associated with increases in serum testosterone testing and treatment initiation over a 4-year period, a JAMA … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 21, 2017 Category: Primary Care Source Type: news

Studies Compare Side Effects of Localized Prostate Cancer Treatments (FREE)
By Kelly Young Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM Two new cohort studies in JAMA shed light on the adverse events associated with various treatments for localized prostate cancer.In the first study, researchers compared patient-reported outcomes at 3 … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 21, 2017 Category: Primary Care Source Type: news

Your NEJM Group Today: Protruding Iris Collarette / Resident Wellness / Florida Family Medicine Opportunity (FREE)
By the Editors Here ' s today ' s offering from NEJM Group:NEJM Clinical Practice Center: Image in Clinical Medicine: A woman presented to an ophthalmologist with allergic … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 20, 2017 Category: Primary Care Source Type: news

All FDA-Approved, Oral Direct-Acting Antivirals for Hepatitis C Safe and Effective for Genotype 1 (FREE)
By Kelly Young Edited by Jaye Elizabeth Hefner, MD The FDA-approved interferon-free regimens for treating hepatitis C appear to be safe and effective, suggests an Annals of Internal Medicine review.Researchers examined 42 randomized trials of oral hepatitis C … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 20, 2017 Category: Primary Care Source Type: news

1 in 4 U.S. Kids Exposed to Secondhand E-Cigarette Aerosols (FREE)
By Amy Orciari Herman Edited by Jaye Elizabeth Hefner, MD Some 24% of U.S. middle and high school students report recent exposure to the vapors from someone else ' s electronic cigarettes, according to a research letter … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 20, 2017 Category: Primary Care Source Type: news

Intradiscal Steroid Injection of " Questionable " Benefit for Low Back Pain with Discopathy (FREE)
By Amy Orciari Herman Edited by Jaye Elizabeth Hefner, MD A single glucocorticoid injection offers short-term relief of chronic back pain associated with discopathy, according to a study in the Annals of Internal Medicine. But the benefits are … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 20, 2017 Category: Primary Care Source Type: news

From the Blogs: What HHS Secretary Tom Price Should Be Saying About Immunizations (FREE)
By the Editors In case you missed it, Secretary of Health and … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 19, 2017 Category: Primary Care Source Type: news

News from ACC 2017: Rivaroxaban vs. Aspirin to Prevent Recurrent VTE / Evolocumab ' s Clinical Outcomes / More... (FREE)
By the Editors The American College of Cardiology ' s annual meeting brought forth a flood of heart-related medical news this weekend. Here ' s a quick look at the studies we thought you ' d be most interested in:Rivaroxaban vs. Aspirin for Recurrent VTE: Nearly 3400 adults with venous thromboembolism who ' d completed 6 –12 months of anticoagulation were randomized to daily rivaroxaban (20 or 10 mg) or aspirin (100 mg). At 1 year, rates of symptomatic recurrent VTE were significantly lower with rivaroxaban (1.5% and 1.2%) than with aspirin (4.4%), with no differences in major bleeding across the groups. Dr. Allan Brett...
Source: Physician's First Watch current issue - March 19, 2017 Category: Primary Care Source Type: news

World ' s Healthiest Arteries on Record Found in Indigenous Bolivian Population (FREE)
By Amy Orciari Herman Edited by Susan Sadoughi, MD, and Andr é Sofair, MD, MPH Researchers have identified a population with the lowest recorded prevalence of coronary artery disease — the Tsimane, an indigenous group living a pre-industrial lifestyle in the Bolivian Amazon. The findings were reported in the Lancet … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 19, 2017 Category: Primary Care Source Type: news

ASCO Issues Guidelines on HPV Vaccination Based on Available Resources (FREE)
By Amy Orciari Herman Edited by Susan Sadoughi, MD, and Andr é Sofair, MD, MPH The American Society of Clinical Oncology has issued guidelines on human papillomavirus (HPV) vaccination according to the resources available in a patient ' s community. Among the recommendations for females, … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 19, 2017 Category: Primary Care Source Type: news

Absorbable Stent Linked to Increase in Cardiac Events (FREE)
By Amy Orciari Herman Edited by Susan Sadoughi, MD, and Andr é Sofair, MD, MPH The Absorb GT1 Bioresorbable Vascular Scaffold is associated with an increased rate of major adverse … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 19, 2017 Category: Primary Care Source Type: news

Your NEJM Group Today: Proposed Healthcare Law vs. ACA / Opioid Use & Misuse by Kids / Virginia Internist Opportunity (FREE)
By the Editors Here ' s what we chose for you from NEJM Group today:NEJM Catalyst: Data Graphic: How does the … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 19, 2017 Category: Primary Care Source Type: news

Most Popular NEJM Group Feature This Week: Cardiovascular Effects of Caffeine (FREE)
By the Editors Here ' s the most clicked-on item we featured … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 17, 2017 Category: Primary Care Source Type: news

Chronic Opioid Use More Common with Long-Acting Opioids, Longer Rx Duration (FREE)
By Kelly Young Edited by Andr é Sofair, MD, MPH Authorizing a second opioid prescription in opioid-naive adults doubles the risk for chronic opioid use, according to an MMWR study.Researchers examined a sample of 1.3 million U.S. adults who were prescribed opioids for the first … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 16, 2017 Category: Primary Care Source Type: news

Your NEJM Group Today: Lower GI Bleeding Clinical Pearls / Zika Rash Described / Alaska Primary Care & Psychiatry Opportunities (FREE)
By the Editors Here ' s what we chose for you from NEJM Group today:NEJM Resident 360: Clinical Pearls: Among patients with brisk … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 16, 2017 Category: Primary Care Source Type: news

Taking Statins on Day of Coronary Bypass Linked to Lower 30-Day Mortality (FREE)
By Amy Orciari Herman Edited by Andr é Sofair, MD, MPH Patients undergoing coronary artery bypass grafting (CABG) fare best when they take a statin on the day of surgery, rather than taking one earlier or not at all, according … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 16, 2017 Category: Primary Care Source Type: news

Your NEJM Group Today: Capping Medicaid Spending / Celiac Disease in Northern Latitudes / California Primary Care Opportunities (FREE)
By the Editors Here ' s what we chose for you from NEJM Group today:NEJM Audio Interview: Capping Medicaid Spending: Dr. Andrew Goodman-Bacon … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 15, 2017 Category: Primary Care Source Type: news

Climate Change Already Affecting Human Health (FREE)
By Kelly Young Edited by Susan Sadoughi, MD, and Richard Saitz, MD, MPH, FACP, DFASAM The Medical Society Consortium on Climate& Health, comprising 11 medical societies, is " sounding … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 15, 2017 Category: Primary Care Source Type: news

Guidelines Issued on Diagnosing Obstructive Sleep Apnea (FREE)
By Amy Orciari Herman Edited by Susan Sadoughi, MD, and Richard Saitz, MD, MPH, FACP, DFASAM The American Academy of Sleep Medicine has issued guidelines on diagnosing obstructive sleep apnea (OSA) in adults.Among the recommendations with a " strong " rating, published … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 15, 2017 Category: Primary Care Source Type: news

Heart Groups Update Guidelines for Treating Heart Valve Disease (FREE)
By Kelly Young Edited by Susan Sadoughi, MD, and Richard Saitz, MD, MPH, FACP, DFASAM The American Heart Association and the American College of Cardiology have updated their guidelines for managing valvular heart disease. The … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 15, 2017 Category: Primary Care Source Type: news

IBS Drug Eluxadoline Poses Increased Pancreatitis Risk to Patients Without Gallbladders (FREE)
By Kelly Young Edited by Susan Sadoughi, MD, and Richard Saitz, MD, MPH, FACP, DFASAM Eluxadoline (Viberzi), used to treat irritable bowel syndrome with diarrhea, is contraindicated in patients without a … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 15, 2017 Category: Primary Care Source Type: news

FDA Advisers: Opana ' s Benefits Don ' t Outweigh Its Risks (FREE)
By Amy Orciari Herman Edited by Susan Sadoughi, MD, and Richard Saitz, MD, MPH, FACP, DFASAM The benefits of the opioid painkiller Opana ER — an extended-release version of oxymorphone — do not … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 15, 2017 Category: Primary Care Source Type: news