Alpha-lipoic acid, apocynin or probiotics influence glutathione status and selected inflammatory parameters in C57/BL6 mice when combined with a low-fat diet
CONCLUSIONS: Supplementation of the tested compounds with LFD appears to have a positive influence on the glutathione redox status of pulmonary tissues and selected inflammatory parameters in mouse blood.PMID:37730940 | DOI:10.1007/s43440-023-00527-8 (Source: Pharmacological Reports)
Source: Pharmacological Reports - September 21, 2023 Category: Drugs & Pharmacology Authors: Paulina Kleniewska Rafa ł Pawliczak Source Type: research
Alpha-lipoic acid, apocynin or probiotics influence glutathione status and selected inflammatory parameters in C57/BL6 mice when combined with a low-fat diet
CONCLUSIONS: Supplementation of the tested compounds with LFD appears to have a positive influence on the glutathione redox status of pulmonary tissues and selected inflammatory parameters in mouse blood.PMID:37730940 | DOI:10.1007/s43440-023-00527-8 (Source: Pharmacological Reports)
Source: Pharmacological Reports - September 21, 2023 Category: Drugs & Pharmacology Authors: Paulina Kleniewska Rafa ł Pawliczak Source Type: research
Alpha-lipoic acid, apocynin or probiotics influence glutathione status and selected inflammatory parameters in C57/BL6 mice when combined with a low-fat diet
CONCLUSIONS: Supplementation of the tested compounds with LFD appears to have a positive influence on the glutathione redox status of pulmonary tissues and selected inflammatory parameters in mouse blood.PMID:37730940 | DOI:10.1007/s43440-023-00527-8 (Source: Pharmacological Reports)
Source: Pharmacological Reports - September 21, 2023 Category: Drugs & Pharmacology Authors: Paulina Kleniewska Rafa ł Pawliczak Source Type: research
Alpha-lipoic acid, apocynin or probiotics influence glutathione status and selected inflammatory parameters in C57/BL6 mice when combined with a low-fat diet
CONCLUSIONS: Supplementation of the tested compounds with LFD appears to have a positive influence on the glutathione redox status of pulmonary tissues and selected inflammatory parameters in mouse blood.PMID:37730940 | DOI:10.1007/s43440-023-00527-8 (Source: Pharmacological Reports)
Source: Pharmacological Reports - September 21, 2023 Category: Drugs & Pharmacology Authors: Paulina Kleniewska Rafa ł Pawliczak Source Type: research
Investigating the potential effects of α-synuclein aggregation on susceptibility to chronic stress in a mouse Parkinson's disease model
CONCLUSIONS: Progressive bilateral α-syn aggregation might lead to compensatory activity increase and alterations in emotionally regulated behavior, without affecting stress susceptibility. Understanding how α-syn aggregation and degeneration in specific brain structures contribute to depression and anxiety in PD patients requires further investigation.PMID:37725330 | DOI:10.1007/s43440-023-00530-z (Source: Pharmacological Reports)
Source: Pharmacological Reports - September 19, 2023 Category: Drugs & Pharmacology Authors: Anna Alwani Katarzyna Maziarz Gabriela Burda Monika Jankowska-Kie łtyka Adam Roman Gabriela Łyszczarz Safak Er Justyna Barut Olga Barczyk-Wo źnicka El żbieta Pyza Grzegorz Kreiner Irena Nalepa Piotr Chmielarz Source Type: research
Investigating the potential effects of α-synuclein aggregation on susceptibility to chronic stress in a mouse Parkinson's disease model
CONCLUSIONS: Progressive bilateral α-syn aggregation might lead to compensatory activity increase and alterations in emotionally regulated behavior, without affecting stress susceptibility. Understanding how α-syn aggregation and degeneration in specific brain structures contribute to depression and anxiety in PD patients requires further investigation.PMID:37725330 | DOI:10.1007/s43440-023-00530-z (Source: Pharmacological Reports)
Source: Pharmacological Reports - September 19, 2023 Category: Drugs & Pharmacology Authors: Anna Alwani Katarzyna Maziarz Gabriela Burda Monika Jankowska-Kie łtyka Adam Roman Gabriela Łyszczarz Safak Er Justyna Barut Olga Barczyk-Wo źnicka El żbieta Pyza Grzegorz Kreiner Irena Nalepa Piotr Chmielarz Source Type: research
Effervescent tablet-assisted deep eutectic solvent based on magnetic nanofluid for liquid phase microextraction of tyrosine kinase inhibitors in plasma samples by high-performance liquid chromatography
CONCLUSIONS: The developed method displayed high sensitivity, low consumption of solvent, low cost, simplicity, high recoveries, short extraction time, and good repeatability for determination of three anti-cancer drugs in human plasma samples.PMID:37717246 | DOI:10.1007/s43440-023-00524-x (Source: Pharmacological Reports)
Source: Pharmacological Reports - September 17, 2023 Category: Drugs & Pharmacology Authors: Khosrou Abdi Maryam Ezoddin Laleh Adlnasab Bahar Aziz Kabiri Mohammad Ali Karimi Somaye Behnamipour Houman Alimoradi Source Type: research
Effervescent tablet-assisted deep eutectic solvent based on magnetic nanofluid for liquid phase microextraction of tyrosine kinase inhibitors in plasma samples by high-performance liquid chromatography
CONCLUSIONS: The developed method displayed high sensitivity, low consumption of solvent, low cost, simplicity, high recoveries, short extraction time, and good repeatability for determination of three anti-cancer drugs in human plasma samples.PMID:37717246 | DOI:10.1007/s43440-023-00524-x (Source: Pharmacological Reports)
Source: Pharmacological Reports - September 17, 2023 Category: Drugs & Pharmacology Authors: Khosrou Abdi Maryam Ezoddin Laleh Adlnasab Bahar Aziz Kabiri Mohammad Ali Karimi Somaye Behnamipour Houman Alimoradi Source Type: research
The effect of selected aminoglycoside antibiotics on human serum albumin antioxidant activity: a spectroscopic and calorimetric comparative study
CONCLUSIONS: Based on the spectroscopic and microcalorimetric data, both KAN and NEO can be considered modulators of the HSA antioxidant activity.PMID:37704832 | DOI:10.1007/s43440-023-00529-6 (Source: Pharmacological Reports)
Source: Pharmacological Reports - September 13, 2023 Category: Drugs & Pharmacology Authors: Wojciech Rog óż Kinga Mac Aleksandra Owczarzy Karolina Kulig Jadwiga Po życka Ma łgorzata Maciążek-Jurczyk Source Type: research
The effect of selected aminoglycoside antibiotics on human serum albumin antioxidant activity: a spectroscopic and calorimetric comparative study
CONCLUSIONS: Based on the spectroscopic and microcalorimetric data, both KAN and NEO can be considered modulators of the HSA antioxidant activity.PMID:37704832 | DOI:10.1007/s43440-023-00529-6 (Source: Pharmacological Reports)
Source: Pharmacological Reports - September 13, 2023 Category: Drugs & Pharmacology Authors: Wojciech Rog óż Kinga Mac Aleksandra Owczarzy Karolina Kulig Jadwiga Po życka Ma łgorzata Maciążek-Jurczyk Source Type: research
The effect of selected aminoglycoside antibiotics on human serum albumin antioxidant activity: a spectroscopic and calorimetric comparative study
CONCLUSIONS: Based on the spectroscopic and microcalorimetric data, both KAN and NEO can be considered modulators of the HSA antioxidant activity.PMID:37704832 | DOI:10.1007/s43440-023-00529-6 (Source: Pharmacological Reports)
Source: Pharmacological Reports - September 13, 2023 Category: Drugs & Pharmacology Authors: Wojciech Rog óż Kinga Mac Aleksandra Owczarzy Karolina Kulig Jadwiga Po życka Ma łgorzata Maciążek-Jurczyk Source Type: research
The effect of selected aminoglycoside antibiotics on human serum albumin antioxidant activity: a spectroscopic and calorimetric comparative study
CONCLUSIONS: Based on the spectroscopic and microcalorimetric data, both KAN and NEO can be considered modulators of the HSA antioxidant activity.PMID:37704832 | DOI:10.1007/s43440-023-00529-6 (Source: Pharmacological Reports)
Source: Pharmacological Reports - September 13, 2023 Category: Drugs & Pharmacology Authors: Wojciech Rog óż Kinga Mac Aleksandra Owczarzy Karolina Kulig Jadwiga Po życka Ma łgorzata Maciążek-Jurczyk Source Type: research
HDAC3 inhibition protects against peripheral and central alterations in an animal model of obesity
CONCLUSION: Therefore, HDAC3 inhibition can represent a promising pharmacological target for the treatment of obesity.PMID:37698830 | DOI:10.1007/s43440-023-00528-7 (Source: Pharmacological Reports)
Source: Pharmacological Reports - September 12, 2023 Category: Drugs & Pharmacology Authors: Franci éle Romero Machado Silvana Peterini Boeira Vandreza Cardoso Bortolotto St ífani Machado Araujo M árcia Rósula Poetini Cristini Escobar Viana Marina Prigol Leandro Cattelan Souza Marcelo Gomes de Gomes Source Type: research
HDAC3 inhibition protects against peripheral and central alterations in an animal model of obesity
CONCLUSION: Therefore, HDAC3 inhibition can represent a promising pharmacological target for the treatment of obesity.PMID:37698830 | DOI:10.1007/s43440-023-00528-7 (Source: Pharmacological Reports)
Source: Pharmacological Reports - September 12, 2023 Category: Drugs & Pharmacology Authors: Franci éle Romero Machado Silvana Peterini Boeira Vandreza Cardoso Bortolotto St ífani Machado Araujo M árcia Rósula Poetini Cristini Escobar Viana Marina Prigol Leandro Cattelan Souza Marcelo Gomes de Gomes Source Type: research
Transient plasticity response is regulated by histone deacetylase inhibitor in oxygen-glucose deprivation condition
CONCLUSIONS: Together, this study revealed the protection of VPA in ex vivo OGD-induced pathological form of neuroplasticity and in vivo PTI-induced brain damage and motor dysfunction through rescuing GABAergic deficiency and the pathological hallmarks of ischemia.PMID:37695500 | DOI:10.1007/s43440-023-00525-w (Source: Pharmacological Reports)
Source: Pharmacological Reports - September 11, 2023 Category: Drugs & Pharmacology Authors: Ming-Chia Chu Wei-Chang Mao Han-Fang Wu Yun-Chi Chang Ting-I Lu Chi-Wei Lee Yueh-Jung Chung Tsung-Han Hsieh Hsun-Shuo Chang Yih-Fung Chen Chia-Hsien Lin Chih-Wei Tang Hui-Ching Lin Source Type: research
