Detection of Mpox Virus in Seminal Fluids: Implications for Sexual Transmission
New Microbiol. 2024 Jan;46(4):317-321.ABSTRACTThe 2022 outbreak of the human mpox virus, formerly known as monkeypox, raised global health concerns with widespread transmission across multiple countries. Sexual transmission emerged as a significant mode of spread, particularly among high-risk groups like MSM and PLWH. This manuscript focuses on the implications of seminal fluids in the transmission of mpox. The virus has been detected in various bodily fluids, including semen, indicating the potential for sexual transmission. Studies have reported high positivity rates of mpox DNA in seminal fluids. Despite some concern ab...
Source: New Microbiologica - January 22, 2024 Category: Microbiology Authors: Angelo Roberto Raccagni Antonella Castagna Silvia Nozza Source Type: research
Meta-Analysis of Demographic Disparities in Monkeypox Infections among Diverse Populations
New Microbiol. 2024 Jan;46(4):322-331.ABSTRACTThis meta-analysis aims to investigate demographic disparities in monkeypox (mpox) infections among various groups based on ethnicity, sexual partners, and gender. The study includes data from 2,646 to 4,002 patients across various outcomes. Among racial demographics, black populations show a lower odds ratio for mpox compared to white populations (OR=0.08 [0.01, 0.45], 95% CI, p=0.004). However, no statistically significant difference is found when comparing black populations with Hispanic or Asian populations (OR=0.72 [0.46, 1.11], p=0.13). There was a substantial disparity b...
Source: New Microbiologica - January 22, 2024 Category: Microbiology Authors: Mahmoud Kandeel Source Type: research
Research on the Artemia nauplii microorganism compositions based on metagenomics next-generation sequencing
In conclusion, the Vibrio species were significantly reduced after treatment with TCCA, indicating that TCCA might be an alternative to antibiotics used for live food sterilization in marine aquaculture.PMID:38252043 (Source: New Microbiologica)
Source: New Microbiologica - January 22, 2024 Category: Microbiology Authors: Yang Xu Dayan Hu Haihua Cheng Fei Peng Qiang Gao Source Type: research
Extent and Resistance Patterns of Gram-negative Bacteria Isolated From 13 Hospitals in Shaoxing, Zhejiang Province
New Microbiol. 2024 Jan;46(4):340-347.ABSTRACTGram-negative bacteria are increasingly recognized as the sauce of severe infections. In recent years, epidemiological data has indicated that the drug resistance rate of Gram-negative bacteria has significantly increased. We analyzed the epidemiological surveillance data of gram-negative bacteria in Shaoxing City in 2021 by retrospectively collecting drug susceptibility data of Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Enterobacter cloacae, Pseudomonas aeruginosa, Acinetobacter baumannii, and Burkholderia cepacian from thirteen tertiary hospitals. A total of ...
Source: New Microbiologica - January 22, 2024 Category: Microbiology Authors: Yiqing Zhou Meichun Liang Xiaojiao Zhang Qiuli He Li Lv Guofeng Mao Source Type: research
In vitro Activity of Cefmetazole and Flomoxef among Extended-Spectrum Beta-Lactamase producing Enterobacterales
New Microbiol. 2024 Jan;46(4):348-353.ABSTRACTIn this age of antimicrobial resistance (AMR), improving treatment using existing antibiotics is desirable. Extended-spectrum beta-lactamase (ESBL)-producing Enterobacterales (ESBL-E) are high priority AMR pathogens according to the World Health Organization. Cephamycin-class beta- lactams are tolerant to hydrolysis by ESBL activity and have bactericidal effects on ESBL-E. The aim of the present study was to compare the in vitro minimum inhibitory concentration (MIC) of cefmetazole (CMZ) and flomoxef (FMOX) among ESBL-E strains. This was a retrospective study using microbiology...
Source: New Microbiologica - January 22, 2024 Category: Microbiology Authors: Koji Iio Hideharu Hagiya Tsukasa Higashionna Fumio Otsuka Source Type: research
Characteristics of inhibitory active substances produced by Pseudoalteromonas SW-1
New Microbiol. 2024 Jan;46(4):354-360.ABSTRACTTo confirm the antagonistic activity characterization of the strain Pseudoalteromonas SW-1 (P. SW-1), its cell-free supernatant (CFS) was studied against a clam pathogenic strain of Vibrio Alginolyticu MP-1 (V.MP-1). The CFS of P. SW-1 exhibited evident antagonistic activities against the pathogens, and the absorbance value (600 nm) of V. MP-1 remained at a lower level at 24 h when compared with the control. The results showed that the inhibitory activities of strain P. SW-1 CFS showed differences after treatment with heat, acid and alkali, and proteinase K. The CFS of P. SW-1 ...
Source: New Microbiologica - January 22, 2024 Category: Microbiology Authors: Xing Sun Xin Xu Xuhui Wang Tongtong Tang Weiwei Zhang Yuhua Ma Source Type: research
Comparative Evaluation of Medicinal Plant Extracts and Antimicrobial Magistrals
New Microbiol. 2024 Jan;46(4):361-366.ABSTRACTThe in vitro antimicrobial activity of the active ingredient in antimicrobial magistral drug formulations and plant extracts used in folk medicine were investigated comparatively. Borax, sulfur colloid, hydrogen peroxide, benzoic acid, rivanol, brilliant green and plant extracts as active ingredients, namely: Helianthus tuberosus tuber-H2O (aqueous extract), Cydonia oblonga leaves-H2O, Allium porrum whole plant-H2O, Cistus laurifolius leaves-EtOH, Solanum muricalum-H2O, and Fumaria cilicica leaves-EtOH were studied to determine their antimicrobial activity against different bac...
Source: New Microbiologica - January 22, 2024 Category: Microbiology Authors: Hager Muftah Berrin Özçelik Ozlem Oyardi Didem Deliorman Orhan Source Type: research
Optimizing the antiretroviral treatment focusing on long-term effectiveness and a person-centered approach. Consensus Guidance Using a Delphi Process
New Microbiol. 2024 Jan;46(4):367-380.ABSTRACTDefinitive data on the long-term success of the latest antiretroviral therapy (ART) strategies are still lacking. A panel of infectious diseases specialists was convened to develop a consensus on how to tailor and follow ART over time. Panelists used a Delphi technique to develop a list of statements describing preferred management approaches for ART and patient monitoring and quality of life evaluation. Ninety infectious diseases specialists from several Infectious Diseases Centers in Italy participated in the consensus process. A consensus was reached on virological and immun...
Source: New Microbiologica - January 22, 2024 Category: Microbiology Authors: Franco Maggiolo Sergio Lo Caputo Stefano Bonora Marco Borderi Antonella Cingolani Gabriella D'Ettorre Antonio Di Biagio Simona Di Giambenedetto Cristina Gervasoni Giovanni Guaraldi Paolo Maggi Lucia Taramasso Source Type: research
Inhibition of canine parvovirus 2 (CPV-2) replication by TAT-scFv through targeting of the viral structural protein VP2 of CPV-2
In this study, we fused the transactivating transcriptional activator peptide (TAT) with scFv. TAT-scFv was identified by Western blot. CCK8 kit was used to detect the toxicity of TAT-scFv to cells. The binding activity of TAT-scFv to CPV-2-VP2 was detected by DAS ELISA. The cell uptake rate of TAT-scFv was assessed by IFA. After infection with CPV-2, F81 cells were incubated by TAT-scFv. The replication of virus was measured to determine the neutralization effect of TAT-scFv on intracellular and extracellular viruses. Protein docking was used to predict the amino acid (AA) sites of VP2 binding to TAT-scFv. TAT-scFv was ex...
Source: New Microbiologica - January 22, 2024 Category: Microbiology Authors: Kun Liu Peng Xu Yuchen Li Jiali Qin Jiping Zhu Yi Li Source Type: research
Neonatal severe COVID-19 infection complicated by Staphilococcus aureus could be misinterpreted as MIS-C?: case report and review of literature
New Microbiol. 2024 Jan;46(4):390-394.ABSTRACTAt 23 days of life a neonate presented to the emergency room with crying and decreased oral intake. His parents were positive to SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), but he turned out negative. After one week he was admitted to NICU (neonatal intensive care unit) for respiratory failure, and nasopharyngeal swab (PCR test: polymerase chain reaction test) was positive for SARS-CoV-2. On examination the child had fever, tachy-dyspnea, reduced oxygen saturation, tachycardia, abdominal distension and tenderness, irritability and hypertonia. Blood exam showed...
Source: New Microbiologica - January 22, 2024 Category: Microbiology Authors: Giovanna Stringari Laura Nai Fovino Aldo Naselli Francesca Tota Michela Capogna Silvia Graziani Massimo Soffiati Source Type: research
Successful control measures to treat the transmission of Candida auris in Northern Italian Hospital
We describe the first documented case of C. auris in northeastern Italy and the measures applied to contain the transmission that led to zero collateral infections.PMID:38252051 (Source: New Microbiologica)
Source: New Microbiologica - January 22, 2024 Category: Microbiology Authors: Federico Giovagnorio Nicholas Geremia Claudio Scarparo Sandro Panese Simone Bradariolo Chiara Berti Maria Solinas Maurizio Sanguinetti Vittorio Selle Andrea Cozza Saverio Giuseppe Parisi Giovanni Carretta Source Type: research
18S rRNA sequencing and homology analysis of post-traumatic bloodstream infection with Saprochaete clavata (Magnusiomyces clavatus) and a case report
We present a case of bloodstream infection with Saprochaete clavata following an abdominal steel impact injury in a 52-year-old man, whose non-healing abdominal wound was also highly suspected of being caused by Saprochaete clavata. Saprochaete clavata is a very uncommon fungal pathogen. Our case is distinctive in that previous reports have typically involved immunocompromised, malignant, or leukemic patients. In contrast, our case involved a middle-aged man in good health who had ileal perforation repair for gastrointestinal perforation. Post-surgery, Saprochaete clavata was isolated from the incision exudate and blood sa...
Source: New Microbiologica - January 22, 2024 Category: Microbiology Authors: Wei Jia Guang Chen Wanxiang Li Jie Ma Xue Zhao Source Type: research
PRESTIGIO RING: "An 80-year-old man living with HIV resistant to all four antiretroviral classes and desiring treatment simplification"
New Microbiol. 2024 Jan;46(4):407-411.ABSTRACTPeople aging with 4 antiretroviral class resistant HIV are a very challenging population. It is difficult to build up a fully suppressive regimen, and the high prevalence of comorbidities and polypharmacy may cause drug-drug interactions and put adherence at risk. We herein present the case of an 80-year-old man, participating in the PRESTIGIO registry, asking for a reduction in his antiretroviral burden while on polypharmacy for his comorbidities.PMID:38252053 (Source: New Microbiologica)
Source: New Microbiologica - January 22, 2024 Category: Microbiology Authors: Maria Mazzitelli Maurizio Zazzi Giulia Marchetti Vincenzo Spagnuolo Maria Mercedes Santoro Emanuele Foc à Annamaria Cattelan Antonella Castagna Source Type: research
First case of Chryseobacterium gallinarum bloodstream infection: a diagnostic and therapeutic challenge for an emerging pathogen
New Microbiol. 2024 Jan;46(4):412-415.ABSTRACTChryseobacterium spp. belongs to the Flavobacteriaceae family and is a rod-shaped gram-negative, glucose non-fermenting, non-motile bacterium ubiquitous in the environment. In humans, Chryseobacterium may be responsible for infections such as urinary tract infections (UTI) and ventriculitis with a pathogenic burden increasing in recent years. Chryseobacterium gallinarum was isolated for the first time in 2014 in a pharyngeal scrape sample of chicken and, until now, only one case of human UTI has been described in a pregnant 20-year-old Indian patient. Herein, we report the firs...
Source: New Microbiologica - January 22, 2024 Category: Microbiology Authors: Mattia Genco Antonio Curtoni Paolo Bottino Silvia Scabini Silvia Corcione Davide Vita Luisa Guarrasi Gabriele Bianco Alessandro Bondi Daniela Risso Rossana Cavallo Cristina Costa Source Type: research
Clinical characteristics of 14 cases of Chlamydia psittaci pneumonia
New Microbiol. 2024 Jan;46(4):416-423.ABSTRACTAmong 14 patients with C. psittaci pneumonia, there were 9 critical and 5 non-critical cases. Ten patients improved clinically and were discharged to home; however, four patients died. Seven patients had a history of contact with birds or poultry. All 14 patients had a high fever as the presenting symptom, but most had a normal white blood cell count. Most of the patients had a significant increase in high-sensitivity C-reactive protein and procalcitonin levels. The lymphocyte count in the critical group was considerably lower than in the non-critical group. Patients in the cri...
Source: New Microbiologica - January 22, 2024 Category: Microbiology Authors: Binbin Cheng Jun Wang Lin Lin Dexiang Yang Xiaofeng Liu Hao Wu Source Type: research
