Development of a predictive nomogram for 28-day mortality risk in non-traumatic or post-traumatic subarachnoid hemorrhage patients
ConclusionThe study identified independent risk factors associated with the 28-day mortality risk and developed predictive nomogram models for both non-traumatic and post-traumatic SAH patients. The nomogram holds promise in guiding prognosis improvement strategies for patients with SAH. (Source: Neurological Sciences)
Source: Neurological Sciences - April 16, 2024 Category: Neurology Source Type: research
Bilateral delayed non-ischemic enhancing brain lesions after treatment with flow-diverter
(Source: Neurological Sciences)
Source: Neurological Sciences - April 16, 2024 Category: Neurology Source Type: research
Marchiafava-Bignami disease: why not Marchiafava-Bignami-Carducci disease?
AbstractThe Marchiafava-Bignami disease has a curious backstory, namely, the publication in 1898 of theContribution to the Study of Nonsuppurative Encephalitis (Carducci A in Riv Psicol Psichiat Neuropat 8-9:125-135,1898), in which the neo-graduate Agostino Carducci described the disease that the pathologists Ettore Marchiafava and Amico Bignami would report 5 years later. (Source: Neurological Sciences)
Source: Neurological Sciences - April 16, 2024 Category: Neurology Source Type: research
New insights on the potential effect of orexin receptor antagonist suvorexant on Parkinson ’s disease symptoms
(Source: Neurological Sciences)
Source: Neurological Sciences - April 16, 2024 Category: Neurology Source Type: research
A case of exacerbated encephalopathy with stroke-like episodes and lactic acidosis triggered by metformin in a patient with MELAS
AbstractMitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) is a maternally inherited multisystemic disorder caused by mutations in mitochondrial DNA that result in cellular energy deficiency. MELAS affects the most metabolically active organs, including the brain, skeletal muscles, cochlea, retina, heart, kidneys, and pancreas. As a result, about 85% of carriers of m.3243A > G, the most common mutation in MELAS, develop diabetes by the age of 70. Although metformin is the most widely prescribed drug for diabetes, its usefulness in mitochondrial dysfunction remains controversi...
Source: Neurological Sciences - April 16, 2024 Category: Neurology Source Type: research
Using an expanded algorithm to estimate prevalence of amyotrophic lateral sclerosis in U.S. and UK
ConclusionsThe expanded algorithm enabled the identification of a large population with ALS, or possible ALS, and the estimation of ALS prevalence in MarketScan and CPRD. (Source: Neurological Sciences)
Source: Neurological Sciences - April 16, 2024 Category: Neurology Source Type: research
Correction to: Cognitive function in amyotrophic lateral sclerosis: a cross ‑sectional and prospective pragmatic clinical study with review of the literature
(Source: Neurological Sciences)
Source: Neurological Sciences - April 16, 2024 Category: Neurology Source Type: research
Myotonic dystrophy type 1 in South Korea: a comprehensive analysis of cancer and comorbidity risks
ConclusionsDM1 patients have a noteworthy occurrence of several comorbidities such as cancer, diabetes, thyroid dysfunction, and earlier cataract surgery. This highlights the importance of a comprehensive and integrative approach to the management and treatment of DM1, going beyond addressing only the primary neuromuscular symptoms. More research is required to understand the underlying mechanisms contributing to these comorbidities in DM1 patients, which may inform preventative measures and guide improvements in patient care. (Source: Neurological Sciences)
Source: Neurological Sciences - April 13, 2024 Category: Neurology Source Type: research
Expanding SPG18 clinical spectrum: autosomal dominant mutation causes complicated hereditary spastic paraplegia in a large family
We report the first AD SPG18 family with a complicated phenotype, and we ruled out a dominant negative effect of V168M on erlin2 oligomerization. Therefore, our data do not support the hypothesis of a relationship between the mode of inheritance and the phenotype, but confirm the multifaceted nature of SPG18 on both genetic and clinical point of view. Clinicians should be aware of the importance of conducting an in-depth clinical evaluation to unmask all the possible manifestations associated to an only apparently pure SPG18 phenotype. We confirm the genotype –phenotype correlation between V168M and ALS emphasizing the v...
Source: Neurological Sciences - April 12, 2024 Category: Neurology Source Type: research
Cognitive assessment during the phases of a spontaneous migraine: a prospective cohort study
ConclusionThe headache and postdromal phase of a migraine day was associated with objective evidence of cognitive dysfunction in patients with episodic migraine. (Source: Neurological Sciences)
Source: Neurological Sciences - April 12, 2024 Category: Neurology Source Type: research
Acute ischemic stroke as initial manifestation of cardiac amyloidosis
(Source: Neurological Sciences)
Source: Neurological Sciences - April 11, 2024 Category: Neurology Source Type: research
Effects of different modalities of transcranial magnetic stimulation on post-stroke cognitive impairment: a network meta-analysis
ConclusionsHigh-frequency TMS stimulation has a better overall effect on improving cognitive functions and activities of daily living, such as attention and memory in stroke patients. (Source: Neurological Sciences)
Source: Neurological Sciences - April 11, 2024 Category: Neurology Source Type: research
Correction to: Brivaracetam use in clinical practice: a Delphi consensus on its role as first add ‑on therapy in focal epilepsy and beyond
(Source: Neurological Sciences)
Source: Neurological Sciences - April 11, 2024 Category: Neurology Source Type: research
Serum and CSF cytokine profiles in SARS-CoV-2-associated polyradiculitis depend on many influencing factors
(Source: Neurological Sciences)
Source: Neurological Sciences - April 10, 2024 Category: Neurology Source Type: research
Multiple sclerosis associated with adalimumab use in ankylosing spondylitis
(Source: Neurological Sciences)
Source: Neurological Sciences - April 10, 2024 Category: Neurology Source Type: research
