Biphasic Clinical Trajectory in Pneumococcal Meningitis from Cerebral Infarcts
(Source: Neurocritical Care)
Source: Neurocritical Care - April 17, 2024 Category: Neurology Source Type: research

Survivorship After Neurocritical Care: A Scoping Review of Outcomes Beyond Physical Status
AbstractFollowing intensive care unit hospitalization, survivors of acute neurological injury often experience debilitating short-term and long-term impairments. Although the physical/motor impairments experienced by survivors of acute neurological injury have been described extensively, fewer studies have examined cognitive, mental health, health-related quality of life (HRQoL), and employment outcomes. This scoping review describes the publication landscape beyond physical and/or motor sequelae in neurocritical care survivors. Databases were searched for terms related to critical illness, intensive care, and outcomes fro...
Source: Neurocritical Care - April 15, 2024 Category: Neurology Source Type: research

Analysis of Cerebral Spinal Fluid Drainage and Intracranial Pressure Peaks in Patients with Subarachnoid Hemorrhage
ConclusionsFindings indicate that effects of CSF drainage via EVD and LD differ. Higher amounts and higher proportions of LD volumes were associated with better outcomes, suggesting a potential quantity-dependent protective effect. Optimizing LD volume and mitigating ICP spikes may be a strategy to improve patient outcomes after aSAH.Clinical trial registration: ClinicalTrials.gov identifier: NCT01258257. (Source: Neurocritical Care)
Source: Neurocritical Care - April 15, 2024 Category: Neurology Source Type: research

A Comatose State in Search of a Name: A History of Its Terminology and Semiology
(Source: Neurocritical Care)
Source: Neurocritical Care - April 15, 2024 Category: Neurology Source Type: research

Point-of-Care Ultrasound to Rapidly Detect a Malpositioned Ventriculoperitoneal Shunt
(Source: Neurocritical Care)
Source: Neurocritical Care - April 15, 2024 Category: Neurology Source Type: research

Covert Consciousness in Acute Brain Injury Revealed by Automated Pupillometry and Cognitive Paradigms
ConclusionsAutomated pupillometry combined with mental arithmetic can identify cognitive efforts, and hence covert consciousness, in ICU patients with acute DoC. (Source: Neurocritical Care)
Source: Neurocritical Care - April 11, 2024 Category: Neurology Source Type: research

Mortality, Functional Status, and Quality of Life after 5 Years of Patients Admitted to Critical Care for Spontaneous Intracerebral Hemorrhage
ConclusionsIn patients admitted to the intensive care unit with a diagnosis of nontraumatic intracerebral hemorrhage, hospital mortality up to 90  days after admission is very high. Between 90 days and 5 years after admission, mortality is not high. A large percentage of survivors presented a significant deficit in quality of life and functional status, although with progressive improvement over time. Five years after the hemorrhagic strok e, a survival of 30% was observed, with a good functional status seen in 20% of patients who had been admitted to the hospital. (Source: Neurocritical Care)
Source: Neurocritical Care - April 8, 2024 Category: Neurology Source Type: research

Evaluation of Post-thrombolytic Events to Determine Appropriate ICU Monitoring Duration for Patients with Ischemic Stroke
ConclusionsOur study demonstrates that sICH, neurological deterioration, and need for ICU intervention rarely occur beyond 12  h after thrombolytic administration. Patients presenting with blood pressures <  140/90 mm Hg, NIHSS scores <  10, and not undergoing mechanical thrombectomy may be best candidates for early de-escalation. Larger prospective studies are needed to more fully evaluate the safety, feasibility, and financial impact of early transition out of the ICU. (Source: Neurocritical Care)
Source: Neurocritical Care - April 8, 2024 Category: Neurology Source Type: research

The Impact of Enteral Nimodipine on Endothelial Cell Apoptosis in an Animal Subarachnoid Hemorrhage Model
ConclusionsThis study suggests that enteral nimodipine may have a neuroprotective function by inhibiting endothelial apoptosis in small arterioles and preventing smooth muscle cell proliferation in large arteries. (Source: Neurocritical Care)
Source: Neurocritical Care - April 8, 2024 Category: Neurology Source Type: research

A Recruitment Maneuver After Apnea Testing Improves Oxygenation and Reduces Atelectasis in Organ Donors After Brain Death
ConclusionsRecruitment maneuver after apnea testing reduces hypoxemia and atelectasis in organ donors after brain death. This effect may translate into more lungs being transplanted. (Source: Neurocritical Care)
Source: Neurocritical Care - April 5, 2024 Category: Neurology Source Type: research

Efficacy and Tolerability of Intranasal Midazolam Administration for Antiseizure Treatment in Adults: A Systematic Review
ConclusionsAdministration of in-MDZ seems promising for the treatment of prolonged epileptic seizures and seizure clusters in adults. Limited evidence suggests that intranasal administration is safe. Further research is warranted because of the heterogeneity of cohorts, the variation in dosages, and the lack of uniformity in defining successful seizure termination. (Source: Neurocritical Care)
Source: Neurocritical Care - April 5, 2024 Category: Neurology Source Type: research

Multidisciplinary Consensus on Curricular Priorities for Pediatric Neurocritical Care Nursing Education: A Modified Delphi Study in the United States
ConclusionsWe report 19 widely accepted curricular priorities that can serve as a standard educational base for PNCC nursing. Developing education for nurses in PNCC will complement PNCC programs with targeted nursing expertise that extends comprehensive specialty care to the bedside. Further work is necessary to effectively execute educational certification programs, implement nursing standards in the field, and evaluate the impact of nursing expertise on patient care and outcomes. (Source: Neurocritical Care)
Source: Neurocritical Care - April 3, 2024 Category: Neurology Source Type: research

The Self-Confirmatory History of Plasmapheresis and IVIG
(Source: Neurocritical Care)
Source: Neurocritical Care - April 3, 2024 Category: Neurology Source Type: research

CPPopt on Medical Devices: The Imitation Game
(Source: Neurocritical Care)
Source: Neurocritical Care - April 3, 2024 Category: Neurology Source Type: research

Effect of Statin Treatment in Patients with Aneurysmal Subarachnoid Hemorrhage: A Network Meta-Analysis
ConclusionsSimvastatin 80 mg might be the most effective intervention in reducing DCI. Additionally, short-term therapy might provide more benefits. Further research with longer follow-up is warranted to validate the current findings in patients with aSAH who are at high risk of DCI. (Source: Neurocritical Care)
Source: Neurocritical Care - April 2, 2024 Category: Neurology Source Type: research