HIV Mutates Around Promising Gene Editing Technology (CRISPR-CAS 9)
HIV can defeat efforts to cripple it with CRISPR gene-editing technology, researchers say. And the very act of editing — involving snipping at the virus’s genome — may introduce mutations that help it to resist attack. At least half a dozen papers over the past three years have explored using the popular CRISPR–Cas9 gene editing technique to combat HIV, but the latest finding, described in a (Source: Nelson Vergel's HIV Blog)
Source: Nelson Vergel's HIV Blog - April 8, 2016 Category: Infectious Diseases Authors: Anonymous Source Type: blogs

Switching HIV+ Patients From Stribld to Genvoya Improved Proteinuria but Not eGFR
CROI 2016 Conference Abstract Number:  795 Safety of Tenofovir Alafenamide in Renal Impairment Author(s):  Anton Pozniak2, Jose R Arribas3, Samir K. Gupta4, Frank A. Post5, Anchalee Avihingsanon6, Gordon Crofoot7, Kenneth A. Lichtenstein8, Moti Ramgopal9, Ploenchan Chetchotisa kd10, Marshall W. Fordyce11 Clinical Research, Gilead Sciences Inc, Foster City, CA, United States. 2 (Source: Nelson Vergel's HIV Blog)
Source: Nelson Vergel's HIV Blog - April 8, 2016 Category: Infectious Diseases Authors: Anonymous Source Type: blogs

New HIV Drug Has Potential for Weekly or Once-Yearly Dosing
One of the surprises at CROI 2016 was the first virological data from a new highly potent NRTI that in a slow-release formulation has the potential for annual dosing and that is undergoing research as both treatment and PrEP.In an oral late-breaker, Jay Grobler from Merck presented results from a dose-ranging study in macaques to develop a model for phase 1 studies with MK-8591 (EFdA).1Baseline (Source: Nelson Vergel's HIV Blog)
Source: Nelson Vergel's HIV Blog - April 8, 2016 Category: Infectious Diseases Authors: Anonymous Source Type: blogs

Life Expectancy Rising in HIV Group Over 50, But Still Lags General Population
Estimated median survival in the HIV group rose from 11.8 years in 1996-1999 to 17.8 years in 2000-2005 and to 22.5 years in 2006-2014. Median survival in general population controls was 30.2 years across all three periods. Mortality rate ratio comparing HIV-positive people with controls was highest among 50- to 55-year-olds (3.8) and declined in each older age group. But in the oldest age group (Source: Nelson Vergel's HIV Blog)
Source: Nelson Vergel's HIV Blog - April 8, 2016 Category: Infectious Diseases Authors: Anonymous Source Type: blogs

HIV Mutates Around Promising Gene Editing Technology (CRISPR-CAS 9)
HIV can defeat efforts to cripple it with CRISPR gene-editing technology, researchers say. And the very act of editing — involving snipping at the virus’s genome — may introduce mutations that help it to resist attack. At least half a dozen papers over the past three years have explored using the popular CRISPR–Cas9 gene editing technique to combat HIV, but the latest finding, described in a (Source: Nelson Vergel's HIV Blog)
Source: Nelson Vergel's HIV Blog - April 7, 2016 Category: Infectious Diseases Authors: Nelson Vergel Source Type: blogs

Switching HIV+ Patients From Stribld to Genvoya Improved Proteinuria but Not eGFR
CROI 2016 Conference Abstract Number:  795 Safety of Tenofovir Alafenamide in Renal Impairment Author(s):  Anton Pozniak2, Jose R Arribas3, Samir K. Gupta4, Frank A. Post5, Anchalee Avihingsanon6, Gordon Crofoot7, Kenneth A. Lichtenstein8, Moti Ramgopal9, Ploenchan Chetchotisakd10, Marshall W. Fordyce11 Clinical Research, Gilead Sciences Inc, Foster City, CA, United States. 2 (Source: Nelson Vergel's HIV Blog)
Source: Nelson Vergel's HIV Blog - April 7, 2016 Category: Infectious Diseases Authors: Nelson Vergel Source Type: blogs

New HIV Drug Has Potential for Weekly or Once-Yearly Dosing
One of the surprises at CROI 2016 was the first virological data from a new highly potent NRTI that in a slow-release formulation has the potential for annual dosing and that is undergoing research as both treatment and PrEP.In an oral late-breaker, Jay Grobler from Merck presented results from a dose-ranging study in macaques to develop a model for phase 1 studies with MK-8591 (EFdA).1Baseline (Source: Nelson Vergel's HIV Blog)
Source: Nelson Vergel's HIV Blog - April 7, 2016 Category: Infectious Diseases Authors: Nelson Vergel Source Type: blogs

Life Expectancy Rising in HIV Group Over 50, But Still Lags General Population
Estimated median survival in the HIV group rose from 11.8 years in 1996-1999 to 17.8 years in 2000-2005 and to 22.5 years in 2006-2014. Median survival in general population controls was 30.2 years across all three periods. Mortality rate ratio comparing HIV-positive people with controls was highest among 50- to 55-year-olds (3.8) and declined in each older age group. But in the oldest age group (Source: Nelson Vergel's HIV Blog)
Source: Nelson Vergel's HIV Blog - April 7, 2016 Category: Infectious Diseases Authors: Nelson Vergel Source Type: blogs

HIV-related wasting can have long-term consequences
People who suffered wasting in the past more vulnerable to frailty in later life Michael Carter Published: 30 November 2015 HIV-associated wasting can have a long-term impact on physical function and quality of life, according to research from the United States published in the online edition of AIDS. The research was conducted by (Source: Nelson Vergel's HIV Blog)
Source: Nelson Vergel's HIV Blog - November 30, 2015 Category: Infectious Diseases Authors: Anonymous Source Type: blogs

HIV-related wasting can have long-term consequences
People who suffered wasting in the past more vulnerable to frailty in later life Michael Carter Published: 30 November 2015 HIV-associated wasting can have a long-term impact on physical function and quality of life, according to research from the United States published in the online edition of AIDS. The research was conducted by (Source: Nelson Vergel's HIV Blog)
Source: Nelson Vergel's HIV Blog - November 29, 2015 Category: Infectious Diseases Authors: Nelson Vergel Source Type: blogs

HPV and HIV: What You Need to Know About Anal Cancer (Video)
Men who have anal sex with men (MSM) are more likely to get anal  HPVthan men who only have sex with women. Researchers estimate that the prevalence of anal HPV among men who only have sex with women is around 15% while anal HPV prevalence for MSM is around 60%. If you add HIV into the mix, infection risk goes up still—one study published by HIV Medicine fo und that 77% of MSM with HIV were also (Source: Nelson Vergel's HIV Blog)
Source: Nelson Vergel's HIV Blog - October 28, 2015 Category: Infectious Diseases Authors: Anonymous Source Type: blogs

HPV and HIV: What You Need to Know About Anal Cancer (Video)
Men who have anal sex with men (MSM) are more likely to get anal HPVthan men who only have sex with women. Researchers estimate that the prevalence of anal HPV among men who only have sex with women is around 15% while anal HPV prevalence for MSM is around 60%. If you add HIV into the mix, infection risk goes up still—one study published by HIV Medicine found that 77% of MSM with HIV were also (Source: Nelson Vergel's HIV Blog)
Source: Nelson Vergel's HIV Blog - October 27, 2015 Category: Infectious Diseases Authors: Nelson Vergel Source Type: blogs

Best Posts on Aging with HIV from TheBody.com This Week
Forum on Aging With HIV: H. Pylori and HIV: What Do I Need to Know? (Editor's Pick)               Forum on Aging With HIV: H. Pylori and HIV: What Do I ... I am very familiar with H. Pylori. I was diagnosed with it using a urea breath test 2 years ago when I was diagnosed with lymphoma on the stomach wall. This was cau... View on www.thebody.com Prev iew by Yahoo   (Source: Nelson Vergel's HIV Blog)
Source: Nelson Vergel's HIV Blog - September 12, 2015 Category: Infectious Diseases Authors: Anonymous Source Type: blogs

Best Posts on Aging with HIV from TheBody.com This Week
Forum on Aging With HIV: H. Pylori and HIV: What Do I Need to Know? (Editor's Pick)               Forum on Aging With HIV: H. Pylori and HIV: What Do I ... I am very familiar with H. Pylori. I was diagnosed with it using a urea breath test 2 years ago when I was diagnosed with lymphoma on the stomach wall. This was cau... View on www.thebody.com Preview by Yahoo   (Source: Nelson Vergel's HIV Blog)
Source: Nelson Vergel's HIV Blog - September 11, 2015 Category: Infectious Diseases Authors: Nelson Vergel Source Type: blogs

Webcast : Beyond the Berlin Patient- How Researchers Are Now Trying to Cure More HIV+ People
Webcast : Beyond the Berlin Patient- How Researchers Are Now Trying to Cure More HIV+ People By Nelson Vergel We all read headlines almost weekly about the latest HIV cure.   After years of being exposed to these inflamed news reports, we may get desensitized to the fact that there is actually progress being made in that field.  Ever since Timothy Brown was proven to be cured, the (Source: Nelson Vergel's HIV Blog)
Source: Nelson Vergel's HIV Blog - September 10, 2015 Category: Infectious Diseases Authors: Anonymous Source Type: blogs