Multidisciplinary Respiratory Medicine This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Focus on the cetirizine use in clinical practice: a reappraisal 30  years later
AbstractAntihistamines are currently one of the most commonly administered categories of drugs. They are used to treat symptoms that are secondary to histamine release, which is typical of certain allergic conditions, including rhinitis, conjunctivitis, asthma, urticaria, and anaphylaxis. Cetirizine belongs to the second-generation family, so, it is very selective for peripheral H1 receptors, is potent and quickly relieves symptoms, exerts additional anti-allergic/anti-inflammatory effects, and is usually well-tolerated. It has been marketed 30  years ago. In these years, a remarkable body of evidence has been built. The...
Source: Multidisciplinary Respiratory Medicine - December 5, 2019 Category: Respiratory Medicine Source Type: research

Image analysis in posttreatment non-small cell lung cancer surveillance: specialists ’ interpretations reviewed by the thoracic multidisciplinary tumor board
ConclusionsIn an experienced MTB, the agreement between imaging specialists and the rest of the MTB with regard to the interpretation of images is high in a setting of posttreatment lung cancer image surveillance. It seems that in cases of disagreements, the rates of more accurate interpretation are well balanced between imaging specialists and the MTB.Trial registrationISRCTN16281786, Date 23. February 2017. (Source: Multidisciplinary Respiratory Medicine)
Source: Multidisciplinary Respiratory Medicine - December 3, 2019 Category: Respiratory Medicine Source Type: research

Clinical course and management of idiopathic pulmonary fibrosis
AbstractIdiopathic pulmonary fibrosis (IPF) is a progressive, fatal interstitial lung disease (ILD) with an unpredictable clinical course. Although IPF is rare, healthcare professionals should consider IPF as a potential cause of unexplained chronic dyspnea and/or cough in middle-aged/elderly patients and refer patients to a pulmonologist for evaluation. Making a diagnosis of IPF requires specialist expertise. Multidisciplinary discussion, involving at minimum a pulmonologist and a radiologist with expertise in the differential diagnosis of ILDs, is required to ensure the most accurate diagnosis. Prompt diagnosis of IPF is...
Source: Multidisciplinary Respiratory Medicine - December 1, 2019 Category: Respiratory Medicine Source Type: research

Daytime noninvasive ventilatory support for patients with ventilatory pump failure: a narrative review
AbstractOver the past three decades, the use of noninvasive ventilation or “NIV” to assuage symptoms of hypoventilation for patients with early onset or mild ventilatory pump failure has been extended to up to the use of continuous noninvasive ventilatory support (CNVS) at full ventilatory support settings as a definitive alternative to tracheostomy mechanical ventilat ion. NVS, along with mechanical insufflation-exsufflation, now provides a noninvasive option for the management of both chronic and acute respiratory failure for these patients. The most common diagnoses for which these methods are useful include chest w...
Source: Multidisciplinary Respiratory Medicine - November 29, 2019 Category: Respiratory Medicine Source Type: research

Correction to: Patients ’ usability of seven most used dry-powder inhalers in COPD
Discussion (pag 6 of 9, just below Fig. 4) must be corrected as follows: (Source: Multidisciplinary Respiratory Medicine)
Source: Multidisciplinary Respiratory Medicine - November 25, 2019 Category: Respiratory Medicine Source Type: research

Sensitization to inhaled allergens in asthmatic children in southern Jordan: a cross-sectional study
ConclusionsSensitization to inhaled allergens is highly prevalent in children with asthma and wheezing episodes in southern Jordan and may be correlated with the severity of the disease. Therefore, appropriate measures to recognize and avoid these allergens are highly recommended. Most children in our study suffered from concomitant allergic rhinitis, indicating that an appropriate diagnosis and treatment of allergic rhinitis could significantly improve asthma control and thus the quality of life of these children.Trial registrationThis study is not a clinical trial. (Source: Multidisciplinary Respiratory Medicine)
Source: Multidisciplinary Respiratory Medicine - November 7, 2019 Category: Respiratory Medicine Source Type: research

Observational vignette study to examine patient and healthcare provider perceived impact of asthma-related exacerbations in the US
ConclusionsUnderstanding the distinctions between how patients and HCPs perceive the impact of exacerbations is important for optimizing patient care. HCPs may be less aware of patient ’s concerns about exacerbation-related pain/discomfort. Studies are needed to further understand patient-HCP interactions regarding asthma-related exacerbations. (Source: Multidisciplinary Respiratory Medicine)
Source: Multidisciplinary Respiratory Medicine - November 4, 2019 Category: Respiratory Medicine Source Type: research

Immunostimulants in respiratory diseases: focus on Pidotimod
AbstractUsefulness of Pidotimod and its role as immunostimulant, has been discussed, we know, for several decades. Nevertheless, there is still much to know. Understanding its mechanisms and its potential usefulness in airway infections and its prevention, asthma both Th2 and non Th2 type, bronchiectasis, as adjuvant in vaccination and in allergen immunotherapy still remains to clearly unveil. The aim of this paper was to provide a useful updated review of the role of the main available immunostimulants, giving particular focus on Pidotimod use and its potentials utility in respiratory diseases. Pidotimod showed its useful...
Source: Multidisciplinary Respiratory Medicine - November 3, 2019 Category: Respiratory Medicine Source Type: research

Observational study of the effects of upper respiratory tract infection on hydration status
ConclusionsIn this pilot observational study, we found no evidence that URTIs such as common cold are associated with dehydration, contrary to popular belief. (Source: Multidisciplinary Respiratory Medicine)
Source: Multidisciplinary Respiratory Medicine - October 30, 2019 Category: Respiratory Medicine Source Type: research

Indoor exposure to particulate matter and volatile organic compounds in dwellings and workplaces and respiratory health in French farmers
ConclusionIndoor chemical air pollution is detrimental to farmers ’ respiratory health. More epidemiological investigations with detailed exposure assessments and clinical measures of respiratory effects are needed in rural settings to corroborate these findings. (Source: Multidisciplinary Respiratory Medicine)
Source: Multidisciplinary Respiratory Medicine - October 1, 2019 Category: Respiratory Medicine Source Type: research

Approaching two decades of cystic fibrosis research in Qatar: a historical perspective and future directions
AbstractCystic fibrosis (CF) is a genetic disease caused by a  defect of CF transmembrane conductance regulator (CFTR) gene. CF affects multiple systems, predominantly with respiratory involvement. In Qatar, researchers have been exploring various aspects of the disease for almost 20 years. PubMed and Google Scholar were reviewed for articles related to CF in Qatar. The first publication appeared in the year 2000. Since then, several studies have been conducted on CF patients in Qatar considering a variety of topics. The presence of the CFTR I1234V mutation in a certain Arab tribe stands out as a distinguishing characte...
Source: Multidisciplinary Respiratory Medicine - September 30, 2019 Category: Respiratory Medicine Source Type: research

Patients ’ usability of seven most used dry-powder inhalers in COPD
ConclusionsUsability is a multifaceted indicator that contributes to assess the factual DPIs ’ convenience in real life. DPIs are characterized by different levels of real-life usability, which can be checked, compared and ranked by means of the GUS score. (Source: Multidisciplinary Respiratory Medicine)
Source: Multidisciplinary Respiratory Medicine - September 12, 2019 Category: Respiratory Medicine Source Type: research

Diagnosing COPD in primary care: what has real life practice got to do with guidelines?
ConclusionsCOPD care in primary practice remains suboptimal. Incorrect approach often leads to incorrect grading and mistreatment. Points for improvement should be identified in further studies. (Source: Multidisciplinary Respiratory Medicine)
Source: Multidisciplinary Respiratory Medicine - September 8, 2019 Category: Respiratory Medicine Source Type: research

Use of narrative medicine to identify key factors for effective doctor –patient relationships in severe asthma
ConclusionsThese approaches of NM are useful in daily clinical practice, with the goal of improving the quality of life (QOL) of patients with severe asthma, even in cases in which the doctor-patient relationship isn ’t initially good. (Source: Multidisciplinary Respiratory Medicine)
Source: Multidisciplinary Respiratory Medicine - September 1, 2019 Category: Respiratory Medicine Source Type: research

Occupational risk factors associated with respiratory symptoms among tannery workers in Mojo town, Southeast Ethiopia, 2018: a comparative cross-sectional study
ConclusionThe prevalence of respiratory symptoms was higher among exposed workers compared to unexposed ones. Sex, employment status, ventilation of working units, absence of occupational health and safety training, and not using personal protective equipment were the factors associated with occupational-related respiratory symptoms. Strategies targeting health and safety training, creating awareness on the use of personal protective equipment, and improving workplace conditions, like the provision of adequate ventilation are useful means for assuaging the condition. (Source: Multidisciplinary Respiratory Medicine)
Source: Multidisciplinary Respiratory Medicine - August 4, 2019 Category: Respiratory Medicine Source Type: research