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Tolypocladium sinense Mycelium Polysaccharide Alleviates Obesity, Lipid Metabolism Disorder, and Inflammation Caused by High Fat Diet via Improving Intestinal Barrier and Modulating Gut Microbiota
ConclusionThe findings show that TSMP can inhibit obesity and alleviates obesity-related lipid metabolism disorders, inflammatory responses, and oxidative stress by modulating the gut microbiota and improving intestinal barrier. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - April 24, 2024 Category: Food Science Authors: Mingjian Bai, Xiaolong Wang, Dongyang Liu, Aofeng Xu, Hao Cheng, Lin Li, Chunjing Zhang Tags: Research Article Source Type: research

Human Breast Milk Exosomal miRNAs are Influenced by Premature Delivery and Affect Neurodevelopment
ConclusionThis study demonstrates that miRNA expression in breast milk exosomes can be influenced by preterm delivery, thereby potentially impacting neurodevelopment in preterm infants. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - April 22, 2024 Category: Food Science Authors: Ling Ma, Yanyan Huo, Qingyuan Tang, Xiulian Wang, Weiqin Wang, Dan Wu, Yicheng Li, Lingyan Chen, Shasha Wang, Yiwen Zhu, Wenli Wang, Yuan Liu, Nanjie Xu, Li Chen, Guangjun Yu, Jinjin Chen Tags: Research Article Source Type: research

The Effect of Coenzyme Q10 Supplementation on Bile Acid Metabolism: Insights from Network Pharmacology, Molecular Docking, and Experimental Validation
ConclusionThis study sheds light on the impact of CoQ10 in bile acids metabolism and offers a new perspective on the application of CoQ10 in metabolic health. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - April 21, 2024 Category: Food Science Authors: Mengcheng Jin, Tangbin Zou, Hairong Huang, Ming Chen, Haoqi Zou, Baoyan Chen, Chengze Lai, Huawen Li, Peiwen Zhang Tags: Research Article Source Type: research

Association of Ultraprocessed Food Consumption with Risk of Cardiovascular Disease Among Individuals with Type 2 Diabetes: Findings from the UK Biobank
ConclusionHigher UPF intakes are associated with increased hazards of CVD among individuals with T2D, and the association is partly mediated through worsening biomarkers of renal function, lipid metabolism, inflammation, and body weight. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - April 20, 2024 Category: Food Science Authors: Yue Li, Yuwei Lai, Tingting Geng, Peng ‐Fei Xia, Jun‐Xiang Chen, Zhou‐Zheng Tu, Kun Yang, Yun‐Fei Liao, Gang Liu, An Pan Tags: Research Article Source Type: research

Fructooligosaccharides Intake during Pregnancy Improves Metabolic Phenotype of Offspring in High Fat Diet ‐Induced Obese Mice
ConclusionThe findings highlight the link between the maternal gut environment and the developmental origin of metabolic syndrome in offspring. These results open novel research avenues into preemptive therapies for metabolic disorders by targeting the maternal gut microbiota. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - April 19, 2024 Category: Food Science Authors: Junki Miyamoto, Yuna Ando, Akari Nishida, Mayu Yamano, Shunsuke Suzuki, Hiromi Takada, Ikuo Kimura Tags: Research Article Source Type: research

High Fat Diet –Wheat Gliadin Interaction and its Implication for Obesity and Celiac Disease Onset: In Vivo Studies
Wheat gluten may play a role for development of life-style related diseases in populations on a high fat diet. Mice feed high fat diet show that wheat gliadin consumption affects glucose and lipid metabolic homeostasis, alters the gut microbiota and the immune cell profile in liver. AbstractThe intestinal immune system plays a crucial role in obesity and insulin resistance. An altered intestinal immunity is associated with changes to the gut microbiota, barrier function, and tolerance to luminal antigens. Lipid metabolism and its unbalance can also contribute to acute and chronic inflammation in different conditions. In ce...
Source: Molecular Nutrition and Food Research - April 18, 2024 Category: Food Science Authors: Yuri Haneishi, Lucia Treppiccione, Francesco Maurano, Diomira Luongo, Junki Miyamoto, Mauro Rossi Tags: Review Source Type: research

Molecular Characterization of the Allergenic Arginine Kinase from the Edible Insect Hermetia illucens (Black Soldier Fly)
ConclusionThe results indicate that the possible allergenicity of AK should be taken in consideration when dealing with novel foods containingH. illucens or its derivatives. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - April 17, 2024 Category: Food Science Authors: Danila Delfino, Barbara Prandi, Luisa Calcinai, Erminia Ridolo, Luca Dellafiora, Lorenzo Pedroni, Francesca Nicoletta, Davide Cavazzini, Tullia Tedeschi, Claudia Folli Tags: Research Article Source Type: research

Front Cover: Profiling of Metabolites in a Fermented Soy Dietary Supplement Reinforces its Role in the Management of Intestinal Inflammation
Mol. Nutr. Food Res. 2024,68,2300770DOI:10.1002/mnfr.202300770The cover image is based on the Research ArticleProfiling of Metabolites in a Fermented Soy Dietary Supplement Reinforces its Role in the Management of Intestinal Inflammation by Richard Ethier et al.,https://doi.org/10.1002/mnfr.202300770 (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - April 16, 2024 Category: Food Science Authors: Richard Ethier, Arun Krishnamurthy, Michael Jeffrey, Thomas A. Tompkins Tags: Front Cover Source Type: research

Issue Information: Mol. Nutr. Food Res. 7'24
(Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - April 16, 2024 Category: Food Science Tags: Issue Information Source Type: research

Assessing and Comparing Potential Allergenicity of Two Partially Hydrolyzed Whey ‐Based Formulas for Infants: A Population‐Based Study in China
ConclusionThe two PHF-Ws have notably high intolerance rates, exceeding 10% among infants with CMA. Therefore, suggesting that PHF-Ws may not be suitable for infants and children with CMA in China. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - April 12, 2024 Category: Food Science Authors: Lijuan Sun, Shiwen Han, Sufang Duan, Like Mao, Fang Li, Zhenhua Tu, Huilian Che Tags: Research Article Source Type: research

Curry ‐Odorants and Their Metabolites Transfer into Human Milk and Urine
ConclusionThe transfer profiles of odorants into milk and urine differ qualitatively, quantitatively, and in temporal aspects. More substances are transferred into urine and the transfer needs a longer period compared with milk. Phase II metabolites are transferred into urine and milk. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - April 11, 2024 Category: Food Science Authors: Marcel W. Debong, Ines Homm, Michael Gigl, Roman Lang, Thomas Hofmann, Andrea Buettner, Corinna Dawid, Helene M. Loos Tags: Research Article Source Type: research

Polyphenol Extracts from Ziziphus jujuba Mill. “Junzao” Attenuates Ulcerative Colitis by Inhibiting the NLRP3 and MAPKs Signaling Pathways and Regulating Gut Microbiota Homeostasis in Mice
ConclusionPERJ probably inhibits the development of UC by suppressing the NLRP3 and MAPKs signaling pathways and regulating gut microbiota homeostasis, and can be considered as a potential resource for preventing UC. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - April 11, 2024 Category: Food Science Authors: Xiaobo Wei, Ni Ma, Wen Yang, Jinhu Tian, Huiyan Liu, Haitian Fang Tags: Research Article Source Type: research

Investigation of Antiproliferative Effects of Combinations of White and Black Garlic Extracts with 5 ‐Fluorouracil (5‐FU) on Caco‐2 Colorectal Adenocarcinoma Cells
In conclusion, aqueous black garlic extract may exhibit pro-oxidant activity despite its high antioxidant capacity. It is worth noting that exposure to heat-treated food and increased sugar content may lead to heightened inflammation and adverse health effects. This study is the first to combine garlic with chemo-preventive drugs like 5-FU in Caco-2 cells. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - April 11, 2024 Category: Food Science Authors: Derya Ozalp Unal, Tevhide Sel Tags: Research Article Source Type: research

Nutritional Sources and Anticancer Potential of Phenethyl Isothiocyanate: Molecular Mechanisms and Therapeutic Insights
Phenethyl Isothiocyanate (PEITC) exhibits its anticancer potential by modulating key signaling pathways, enforcing cell cycle arrest, promoting apoptosis, and enhancing drug efficacy by overcoming multidrug resistance and influencing drug metabolism enzymes. AbstractPhenethyl isothiocyanate (PEITC), a compound derived from cruciferous vegetables, has garnered attention for its anticancer properties. This review synthesizes existing research on PEITC, focusing on its mechanisms of action in combatting cancer. PEITC has been found to be effective against various cancer types, such as breast, prostate, lung, colon, and pancre...
Source: Molecular Nutrition and Food Research - April 11, 2024 Category: Food Science Authors: Shahira M. Ezzat, Rana M. Merghany, Passent M. Abdel Baki, Nariman Ali Abdelrahim, Sohaila M. Osman, Mohamed A. Salem, Sheila I. Pe ña‐Corona, Hernán Cortés, Lashyn Kiyekbayeva, Gerardo Leyva‐Gómez, Javad Sharifi‐Rad, Daniela Calina Tags: Review Source Type: research

A New Insight into Fatty Acid Binding Protein 4 Mechanisms and Therapeutic Implications in Obesity ‐Associated Diseases: A Mini Review
FABP4 (Fatty acid binding protein4), a lipid-binding protein, plays a key role in fat metabolism and is linked to obesity, diabetes, and cardiovascular diseases. Its inhibition could benefit obesity-related conditions, particularly insulin resistance and diabetes. FABP4's release from adipose tissue influences lipid metabolism and insulin function, correlating with BMI and metabolic syndrome, making it a potential target for therapeutic intervention. AbstractFatty acid binding proteins (FABPs), such as FABP4 (aP2, A-FABP), are essential for cellular lipid regulation, membrane –protein interactions, and the modulation of ...
Source: Molecular Nutrition and Food Research - April 10, 2024 Category: Food Science Authors: Feyza Nur Ba şarır Sivri, Seda Çiftçi Tags: Review Source Type: research