Specific amino acid supplementation rescues the heart from lipid overload-induced insulin resistance and contractile dysfunction by targeting the endosomal mTOR–v-ATPase axis
Publication date: Available online 13 July 2021Source: Molecular MetabolismAuthor(s): Shujin Wang, Francesco Schianchi, Dietbert Neumann, Li-Yen Wong, Aomin Sun, Frans A. van Nieuwenhoven, Maurice P. Zeegers, Agnieszka Strzelecka, Umare Col, Jan F.C. Glatz, Miranda Nabben, Joost J.F.P. Luiken (Source: Molecular Metabolism)
Source: Molecular Metabolism - July 13, 2021 Category: Endocrinology Source Type: research
Physiological impact of in vivo stable isotope tracing on cancer metabolism
Publication date: Available online 10 July 2021Source: Molecular MetabolismAuthor(s): Manuel Grima-Reyes, Adriana Martinez-Turtos, Ifat Abramovich, Eyal Gottlieb, Johanna Chiche, Jean-Ehrland Ricci (Source: Molecular Metabolism)
Source: Molecular Metabolism - July 11, 2021 Category: Endocrinology Source Type: research
Epigenetic rewiring of skeletal muscle enhancers after exercise training supports a role in whole-body function and human health
Publication date: Available online 10 July 2021Source: Molecular MetabolismAuthor(s): Kristine Williams, Germán D. Carrasquilla, Lars Roed Ingerslev, Mette Yde Hochreuter, Svenja Hansson, Nicolas J. Pillon, Ida Donkin, Soetkin Versteyhe, Juleen R. Zierath, Tuomas O. Kilpeläinen, Romain Barrès (Source: Molecular Metabolism)
Source: Molecular Metabolism - July 10, 2021 Category: Endocrinology Source Type: research
Pioneer factor Foxa2 enables ligand-dependent activation of type II nuclear receptors FXR and LXRα
Publication date: Available online 8 July 2021Source: Molecular MetabolismAuthor(s): Jessica Kain, Xiaolong Wei, Nihal A. Reddy, Andrew J. Price, Claire Woods, Irina M. Bochkis (Source: Molecular Metabolism)
Source: Molecular Metabolism - July 9, 2021 Category: Endocrinology Source Type: research
Tissue Specific Expression of Cas9 has no Impact on Whole Body Metabolism in Four Transgenic Mouse Lines
Publication date: Available online 8 July 2021Source: Molecular MetabolismAuthor(s): Simon T. Bond, Aowen Zhuang, Christine Yang, Eleanor A.M. Gould, Tim Sikora, Yingying Liu, Ying Fu, Kevin I. Watt, Yanie Tan, Helen Kiriazis, Graeme I. Lancaster, Paul Gregorevic, Darren C. Henstridge, Julie R. McMullen, Peter J. Meikle, Anna C. Calkin, Brian G. Drew (Source: Molecular Metabolism)
Source: Molecular Metabolism - July 9, 2021 Category: Endocrinology Source Type: research
β-Cell pre-miR-21 Induces Dysfunction and Loss of Cellular Identity by Targeting Transforming Growth Factor Beta 2 (Tgfb2) and Smad Family Member 2 (Smad2) mRNAs
Publication date: Available online 9 July 2021Source: Molecular MetabolismAuthor(s): Sara Ibrahim, Macey Johnson, Clarissa Hernandez Stephens, Jerry Xu, Rachel Moore, Andrea Mariani, Christopher Contreras, Farooq Syed, Raghavendra G. Mirmira, Ryan M. Anderson, Emily K. Sims (Source: Molecular Metabolism)
Source: Molecular Metabolism - July 9, 2021 Category: Endocrinology Source Type: research
The dark side of insulin: a primary autoantigen and instrument of self-destruction in type 1 diabetes
Publication date: Available online 7 July 2021Source: Molecular MetabolismAuthor(s): Leonard C. Harrison (Source: Molecular Metabolism)
Source: Molecular Metabolism - July 7, 2021 Category: Endocrinology Source Type: research
Neddylation inhibition ameliorates steatosis in NAFLD by boosting hepatic fatty acid oxidation via the DEPTOR-mTOR axis
Publication date: Available online 18 June 2021Source: Molecular MetabolismAuthor(s): Marina Serrano-Maciá, Jorge Simón, Maria J. González-Rellan, Mikel Azkargorta, Naroa Goikoetxea-Usandizaga, Fernando Lopitz-Otsoa, Diego Saenz De Urturi, Rubén Rodríguez-Agudo, Sofia Lachiondo-Ortega, Maria Mercado-Gomez, Virginia Gutiérrez de Juan, Maider Bizkarguenaga, David Fernández-Ramos, Xabier Buque, Guido A. Baselli, Luca V.C. Valenti, Paula Iruzubieta, Javier Crespo, Erica Villa, Jesus M. Banales (Source: Molecular Metabolism)
Source: Molecular Metabolism - July 6, 2021 Category: Endocrinology Source Type: research
MTORC1 inhibition drives crinophagic degradation of glucagon
Publication date: Available online 2 July 2021Source: Molecular MetabolismAuthor(s): Sangam Rajak, Sherwin Xie, Archana Tewari, Sana Raza, Wu Yajun, Boon-Huat Bay, Paul M. Yen, Rohit A. Sinha (Source: Molecular Metabolism)
Source: Molecular Metabolism - July 3, 2021 Category: Endocrinology Source Type: research
From Type 1 Diabetes Biology to Therapy: The Human Islet Research Network
Publication date: Available online 3 July 2021Source: Molecular MetabolismAuthor(s): John S. Kaddis, Layla Rouse, Audrey V. Parent, Diane C. Saunders, Anath Shalev, Cherie L. Stabler, Doris A. Stoffers, Bridget K. Wagner, Joyce C. Niland (Source: Molecular Metabolism)
Source: Molecular Metabolism - July 3, 2021 Category: Endocrinology Source Type: research
Mild Intermittent Hypoxia Exposure Induces Metabolic and Molecular Adaptations in Men with Obesity
Publication date: Available online 3 July 2021Source: Molecular MetabolismAuthor(s): Rens L.J. van Meijel, Max A.A. Vogel, Johan W.E. Jocken, Lars M.M. Vliex, Joey S.J. Smeets, Nicole Hoebers, Joris Hoeks, Yvonne Essers, Paul F.M. Schoffelen, Henrike Sell, Sander Kersten, Kasper M.A. Rouschop, Ellen E. Blaak, Gijs H. Goossens (Source: Molecular Metabolism)
Source: Molecular Metabolism - July 3, 2021 Category: Endocrinology Source Type: research
NAFLD - a rising metabolic disease
Publication date: Available online 2 July 2021Source: Molecular MetabolismAuthor(s): Anja Zeigerer (Source: Molecular Metabolism)
Source: Molecular Metabolism - July 3, 2021 Category: Endocrinology Source Type: research
SNAP-tag-enabled super-resolution imaging reveals constitutive and agonist-dependent trafficking of GPR56 in pancreatic β-cells
Publication date: Available online 2 July 2021Source: Molecular MetabolismAuthor(s): Oladapo E. Olaniru, Jordan Cheng, Julia Ast, Anastasia Arvaniti, Patricio Atanes, Huang GC, Aileen J.F. King, Peter M. Jones, Johannes Broichhagen, David J. Hodson, Shanta J. Persaud (Source: Molecular Metabolism)
Source: Molecular Metabolism - July 3, 2021 Category: Endocrinology Source Type: research
KBP-066A, a Long-Acting Dual Amylin and Calcitonin Receptor Agonist, Induces Weight Loss and Improves Glycemic Control in Obese and Diabetic Rats
Publication date: Available online 29 June 2021Source: Molecular MetabolismAuthor(s): K.V. Andreassen, A.T. Larsen, N. Sonne, K.E. Mohamed, M.A. Karsdal, K. Henriksen (Source: Molecular Metabolism)
Source: Molecular Metabolism - July 1, 2021 Category: Endocrinology Source Type: research
The transcriptional co-regulator LDB1 is required for brown adipose function
Publication date: Available online 29 June 2021Source: Molecular MetabolismAuthor(s): Jessica D. Kepple, Yanping Liu, Teayoun Kim, Cheryl Cero, James W. Johnson, Glenn C. Rowe, Aaron M. Cypess, Kirk M. Habegger, Martin Young, Chad S. Hunter (Source: Molecular Metabolism)
Source: Molecular Metabolism - June 29, 2021 Category: Endocrinology Source Type: research
