Psoriatic Arthritis: Depressing News on Second- and Later-Line Treatments
(MedPage Today) -- Most patients with psoriatic arthritis (PsA) failed to achieve low disease activity after switching from one targeted therapy to another, real-world data from Scandinavian registries indicated. Moreover, patients became increasingly... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - February 27, 2023 Category: Rheumatology Source Type: news

Rheumatoid Factor and ACPA, Meet Potential New Partners for RA Diagnosis
(MedPage Today) -- Antibodies to peptides not currently used for rheumatoid arthritis (RA) diagnosis helped identify patients with untreated early disease that conventional biomarkers missed, researchers said. Almost two-thirds of blood samples... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - February 3, 2023 Category: Rheumatology Source Type: news

Mileage Varies for Different Hip Surgery Approaches
(MedPage Today) -- Most common types of hip arthroplasty achieve similar clinical improvements, a new meta-analysis indicated, but one particular approach appeared to fall short. With data combined from 63 randomized trials with a total of 4,859... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - January 31, 2023 Category: Rheumatology Source Type: news

Study: Diminished COVID Vaccine Response in Lupus
(MedPage Today) -- Patients with systemic lupus erythematosus (SLE) showed reduced antibody responses following COVID-19 vaccination, with drugs for the condition such as belimumab (Benlysta) and mycophenolate mofetil (MMF) likely to blame, researchers... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - January 30, 2023 Category: Rheumatology Source Type: news

Blood Test Bests Standard OA Prognostic Models in Early Study
(MedPage Today) -- A set of 15 blood-based biomarkers outperformed conventional prediction methods for knee osteoarthritis (OA) progression in a large preliminary study, researchers said. Based on data from 596 individuals with mild to moderate... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - January 25, 2023 Category: Rheumatology Source Type: news

Inflammatory VEXAS Syndrome May Not Be So Uncommon
(MedPage Today) -- VEXAS syndrome, a newly discovered inflammatory disease that has rheumatologic and hematologic features caused by mutations in the UBA1 gene, may be as common as Behcet's disease or myelodysplastic syndrome (MDS), researchers... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - January 24, 2023 Category: Rheumatology Source Type: news

Novel Gout Drug Passes Mid-Stage Test
(MedPage Today) -- An investigational non-purine xanthine oxidase inhibitor for gout treatment, called tigulixostat, appeared effective enough in a phase II trial that a pivotal study is now getting underway. Depending on the dose, 45% to 62... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - January 20, 2023 Category: Rheumatology Source Type: news

Phase III Trials Back Bimekizumab for Spondyloarthritis
(MedPage Today) -- Bimekizumab, an investigational biologic drug targeting interleukin (IL)-17A/F, appeared highly effective in patients with axial spondyloarthritis (axSpA), researchers said. With nearly 600 patients enrolled in two parallel... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - January 17, 2023 Category: Rheumatology Source Type: news

JAK Inhibitor Promising for Polymyalgia Rheumatica
(MedPage Today) -- Tofacitinib (Xeljanz) appeared highly effective against polymyalgia rheumatica (PMR) in a small single-arm trial, researchers said, suggesting another potential alternative to long-term corticosteroids. Among 14 patients in... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - January 9, 2023 Category: Rheumatology Source Type: news

Why Doesn't Exercise Help Everyone With Knee OA?
(MedPage Today) -- People with osteoarthritis (OA) of the knee who got no benefit from an exercise program blamed their other problems with health and life in general for the lack of response, researchers said. In interviews conducted with responders... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - January 4, 2023 Category: Rheumatology Source Type: news

Ashton Kutcher's Autoimmune Vasculitis
(MedPage Today) -- In a clip from an episode of the Paramount+ docuseries "The Checkup: With Dr. David Agus" actor Ashton Kutcher talks about a previous health struggle. About 3 years ago, the "That '70s Show" star "woke up one day and was having... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - January 3, 2023 Category: Rheumatology Source Type: news

Advent-Themed Exercise; Substance Use and Road Accidents
(MedPage Today) -- TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of the Texas Tech University Health Sciences Center... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - December 26, 2022 Category: Rheumatology Source Type: news

Early OA Common in Military Officers After Knee Injury
(MedPage Today) -- Nearly one-fifth of U.S. military officers with a history of traumatic knee injury had developed osteoarthritis (OA) visible on x-rays -- before age 30 in most cases, researchers found. In a prospectively followed cohort of... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - December 20, 2022 Category: Rheumatology Source Type: news

Bispecific Antibodies in Blood Cancers; Exercise and Cognitive Function
(MedPage Today) -- TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of the Texas Tech University Health Sciences Center... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - December 17, 2022 Category: Rheumatology Source Type: news

Weight Loss Program Eases OA Knee Pain ... But Not Much
(MedPage Today) -- Overweight and obese patients with knee osteoarthritis assigned to a diet and exercise program in a randomized trial had greater reductions in pain than a control group, but the difference was small, researchers said. After... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - December 13, 2022 Category: Rheumatology Source Type: news