Rheum Patients on HCQ: Stick With It or Face Heart Consequences
(MedPage Today) -- High levels of adherence to prescribed antimalarial drugs for lupus and rheumatoid arthritis (RA) was associated with markedly lower cardiovascular event rates in one Canadian province, researchers found. Rates for a composite... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - September 11, 2023 Category: Rheumatology Source Type: news

U.S. Unveils First 10 Drugs for Medicare Price Negotiations
(MedPage Today) -- The Centers for Medicare & Medicaid Services (CMS) took a historic step forward in its plans to negotiate the prices of Medicare's most costly prescription drugs by naming the first 10 up for negotiation on Tuesday. The... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - August 29, 2023 Category: Rheumatology Source Type: news

Still No Easy Way to Take RA Patients Off Anti-TNF Drugs
(MedPage Today) -- Rheumatoid arthritis (RA) patients in remission who had tumor necrosis factor (TNF) inhibitors withdrawn stepwise still faced markedly increased risk of disease flares compared with a control group who continued on stable doses... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - August 23, 2023 Category: Rheumatology Source Type: news

Make the Diagnosis: A Man With a Very Painful Knee and a Complex Medical History
(MedPage Today) -- (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - August 9, 2023 Category: Rheumatology Source Type: news

Tool Predicts PsA Progression From Psoriasis, No Fancy Biomarkers Needed
(MedPage Today) -- A risk-prediction algorithm was modestly accurate for identifying patients with psoriasis who are likely to progress to psoriatic arthritis (PsA), researchers reported. Based on patients' demographics and clinical presentations... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - August 9, 2023 Category: Rheumatology Source Type: news

Microbiome Study Provides New Clues to Common Pathology of Inflammatory Conditions
(MedPage Today) -- An alteration in gut microbiome diversity occurred in patients with three different inflammatory conditions, suggesting a common pathology, prospective rRNA sequencing of patients' stool samples showed. Patients with axial spondyloarthritis... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - August 8, 2023 Category: Rheumatology Source Type: news

Gut Biome Altered in Inflammatory Arthritis, but Causal Direction Unclear
(MedPage Today) -- Another study has confirmed that the intestinal microbiome's composition in people with inflammatory arthritis differs from that in other people, and in potentially unhealthy ways -- but whether the microbiome alterations actually... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - July 26, 2023 Category: Rheumatology Source Type: news

Biologics Keep Early RA in Check for at Least 1 Year
(MedPage Today) -- Treatment with at least some biologic drugs significantly reduced 1-year progression of early rheumatoid arthritis (RA) relative to classical small-molecule agents, researchers reported. Patients assigned to certolizumab pegol... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - July 11, 2023 Category: Rheumatology Source Type: news

Check SSc-ILD Patients on Ofev for Malnutrition, Study Suggests
(MedPage Today) -- During nintedanib (Ofev) treatment for interstitial lung disease associated with systemic sclerosis (SSc-ILD), clinicians prescribing the drug should be watchful for an unusual, indirect side effect, trial data suggested. Among... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - June 26, 2023 Category: Rheumatology Source Type: news

Phase II Study: Bispecific Oral Drug Tops Leading JAK Inhibitor for RA
(MedPage Today) -- MILAN -- A novel oral agent that blocks two different kinase enzymes was possibly more effective against rheumatoid arthritis (RA) than the currently approved drug tofacitinib (Xeljanz) in a head-to-head study, a researcher... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - June 6, 2023 Category: Rheumatology Source Type: news

Two-Drug Combo Wins for Refractory Gout
(MedPage Today) -- MILAN -- About half of patients receiving infusions of a novel uricase analog, along with a proprietary rapamycin formulation, in two similarly designed phase III studies got their serum urate under control, after multiple... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - June 3, 2023 Category: Rheumatology Source Type: news

First-in-Class Sjogren's Drug Passes Mid-Stage Test
(MedPage Today) -- MILAN -- An investigational protein drug called dazodalibep with broad-spectrum activity against autoimmune pathways reduced symptoms of Sjögren's syndrome in a two-stage, phase II randomized trial with a unique design... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - June 3, 2023 Category: Rheumatology Source Type: news

Cardiovascular Risk Models Still Fall Short for Arthritis Patients
(MedPage Today) -- MILAN -- Despite longstanding awareness that standard cardiovascular prediction models have not been very accurate for people with inflammatory arthritis, a new study reported here shows that it remains the case. The most... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - June 2, 2023 Category: Rheumatology Source Type: news

More Success for CAR T-Cell Therapy in Rheumatic Disease
(MedPage Today) -- MILAN -- Prospects are improving that autologous chimeric antigen receptor (CAR) T-cell therapy will find a home in rheumatology clinics, in light of favorable results presented here. You may remember that last September... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - June 1, 2023 Category: Rheumatology Source Type: news

JAK Inhibitor Shows Promise in Severe Type of Sclerosis
(MedPage Today) -- The Janus kinase (JAK) inhibitor ruxolitinib (Jakafi) eased the severe inflammatory and dermatologic symptoms of disabling pansclerotic morphea (DPM), an initial clinical series showed. After a series of basic science and in... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - June 1, 2023 Category: Rheumatology Source Type: news