Novel Treatment Appears to Show Benefit in ALS
(MedPage Today) -- DENVER -- A novel treatment candidate for amyotrophic lateral sclerosis (ALS) met its primary safety and secondary endpoints in the phase IIb PARADIGM trial.
ALS patients treated with PrimeC -- a formulation of two FDA-approved... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - April 19, 2024 Category: Neurology Source Type: news
No New Safety Signals Seen With Migraine Prevention Drug
(MedPage Today) -- DENVER -- No new safety signals emerged with daily atogepant (Qulipta) for migraine prevention, an interim analysis of a long-term safety extension study showed, and improvements in efficacy were sustained.
After an average... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - April 16, 2024 Category: Neurology Source Type: news
Possible Pulmonary Benefit With Viltolarsen for Duchenne Muscular Dystrophy
(MedPage Today) -- DENVER -- Viltolarsen (Viltepso) was well tolerated by boys and men with Duchenne muscular dystrophy (DMD), with no new safety signals, according to results from the open-label, phase II Galactic53 trial.
The results also... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - April 16, 2024 Category: Neurology Source Type: news
Algorithm Predicts Disability From Point-of-Care EEGs
(MedPage Today) -- DENVER -- A high seizure burden derived by an artificial intelligence (AI) algorithm was associated with worse outcomes, a retrospective analysis showed.
Hospitalized patients who had a high seizure burden based on a point... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - April 16, 2024 Category: Neurology Source Type: news
I'm an Autistic Doctor. Here's How to Improve Care for Autistic Patients.
(MedPage Today) -- In 1983, I signed up for a paper route at the age of 13. Every morning, I rose early, got on my bike, picked up the papers, and delivered them to my subscribers. After that, I headed off to school and my other activities. I was... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - April 13, 2024 Category: Neurology Source Type: news
The Dying Brain; Obesity Drugs and MS; NurOwn Tries Again
(MedPage Today) -- New research about the dying brain suggested the line between consciousness and death may not be distinct. (The Guardian)
A single fecal microbiota transplantation induced mild but sustained effects on motor symptoms in early... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - April 9, 2024 Category: Neurology Source Type: news
Newborn Screening for SMA Appears to Offer Functional Benefits
(MedPage Today) -- Children with spinal muscular atrophy (SMA) identified by newborn screening showed better motor development with disease-modifying treatment than those diagnosed after symptom onset, a German cohort study showed.
Nine out of... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - April 9, 2024 Category: Neurology Source Type: news
Brain Iron Accumulates With Post-Traumatic Headache
(MedPage Today) -- Brain iron accumulated in people with acute post-traumatic headache, an imaging study showed.
Higher levels of iron based on T2* signal changes were seen in post-traumatic headache participants relative to healthy controls... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - April 5, 2024 Category: Neurology Source Type: news
Givinostat Slows Duchenne Muscular Dystrophy Decline
(MedPage Today) -- Givinostat (Duvyzat) slowed physical decline as measured by stair climbing speed for a subset of boys with Duchenne muscular dystrophy (DMD), according to the phase III trial that supported the drug's recent approval for this... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - April 5, 2024 Category: Neurology Source Type: news
Caffeine and Parkinson's; Brutally Honest Look at Dementia; Three MS Subtypes
(MedPage Today) -- Coffee intake and caffeine metabolites in plasma samples were inversely associated with incident Parkinson's disease. (Neurology)
A Mendelian randomization study did not find a causal relationship between Parkinson's and irritable... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - April 2, 2024 Category: Neurology Source Type: news
Smartphone Tests Detect Frontotemporal Dementia
(MedPage Today) -- Cognitive tests administered through a smartphone mobile application (app) accurately and reliably detected frontotemporal lobar degeneration (FTLD), also known as frontotemporal dementia (FTD), an observational study showed... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - April 1, 2024 Category: Neurology Source Type: news
Stopping High-Efficacy MS Drugs Raises Relapse Risk for Older Patients
(MedPage Today) -- Patients ages 50 or older with non-active multiple sclerosis (MS) who discontinued high-efficacy therapy (HET) had a higher risk of relapse compared with those who continued HET, a matched observational cohort study found.
Time... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - March 27, 2024 Category: Neurology Source Type: news
FDA Questioned on Elon Musk's Neuralink; OTC Pain Relief Warning; Easter Egg Safety
(MedPage Today) -- Note that some links may require registration or subscription.
Rep. Earl Blumenauer (D-Ore.) wants to know why the FDA let Elon Musk's Neuralink implant its device in humans without inspecting its facility after finding possible... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - March 27, 2024 Category: Neurology Source Type: news
Why Alzheimer's Drug Approval Delay? $3 Billion in DMD Gene Therapy; ADHD Prevalence
(MedPage Today) -- Why is donanemab, an investigational anti-amyloid agent for early Alzheimer's disease, facing an approval delay? (The Guardian)
Early use of erenumab (Aimovig) showed sustained efficacy compared with oral migraine preventives... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - March 26, 2024 Category: Neurology Source Type: news
Trump Avoids Talk of Father's Alzheimer ’s; Teens Smell Like Goats; AI Drugs a Bust?
(MedPage Today) -- Note that some links may require registration or subscription.
While former President Trump attacks President Biden as being "cognitively impaired," he avoids talk about his own father's battle with Alzheimer's disease. (Washington... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - March 22, 2024 Category: Neurology Source Type: news
