Novel anthropometric indicators of visceral obesity predict the severity of hyperlipidemic acute pancreatitis
Obesity substantially contributes to the onset of acute pancreatitis (AP) and influences its progression to severe AP. Although body mass index (BMI) is a widely used anthropometric parameter, it fails to deli... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - April 23, 2024 Category: Lipidology Authors: Yi Zhu, Yingbao Huang, Houzhang Sun, Lifang Chen, Huajun Yu, Liuzhi Shi, Weizhi Xia, Xuecheng Sun, Yunjun Yang and Hang Huang Tags: Research Source Type: research

Updated mechanisms of MASLD pathogenesis
Metabolic dysfunction-associated steatotic liver disease (MASLD) has garnered considerable attention globally. Changing lifestyles, over-nutrition, and physical inactivity have promoted its development. MASLD ... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - April 22, 2024 Category: Lipidology Authors: Yuxuan Li, Peipei Yang, Jialu Ye, Qiyuan Xu, Jiaqi Wu and Yidong Wang Tags: Review Source Type: research

The neutrophil-to-apolipoprotein A1 ratio is associated with adverse outcomes in patients with acute decompensated heart failure at different glucose metabolic states: a retrospective cohort study
The present study was performed to assess the association between the neutrophil-to-apolipoprotein A1 ratio (NAR) and outcomes in patients with acute decompensated heart failure (ADHF) at different glucose met... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - April 22, 2024 Category: Lipidology Authors: Weimeng Cheng, Tianyue Li, Xiaohan Wang, Tingting Xu, Ying Zhang, Jianzhou Chen and Zhonghai Wei Tags: Research Source Type: research

Investigating potential biomarkers of acute pancreatitis in patients with a BMI > 30 using Mendelian randomization and transcriptomic analysis
Acute pancreatitis (AP) has become a significant global health concern, and a high body mass index (BMI) has been identified as a key risk factor exacerbating this condition. Within this context, lipid metabol... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - April 22, 2024 Category: Lipidology Authors: Hua Ji, Zheng Tang, Kexin Jiang, Shuang Lyu, Yiwen Zhao, Jiajie Feng, Ruiwu Dai and Hongyin Liang Tags: Research Source Type: research

Polar lipids modify Alzheimer ’s Disease pathology by reducing astrocyte pro-inflammatory signaling through platelet-activating factor receptor (PTAFR) modulation
Pro-inflammatory processes triggered by the accumulation of extracellular amyloid beta (A β) peptides are a well-described pathology in Alzheimer's disease (AD). Activated astrocytes surrounding Aβ plaques cont... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - April 20, 2024 Category: Lipidology Authors: Sakshi Hans, Janelle E. Stanton, Ann Katrin Sauer, Katie Shiels, Sushanta Kumar Saha, Ronan Lordan, Alexandros Tsoupras, Ioannis Zabetakis and Andreas M. Grabrucker Tags: Research Source Type: research

Is cholesterol both the lock and key to abnormal transmembrane signals in Autism Spectrum Disorder?
Disturbances in cholesterol homeostasis have been associated with ASD. Lipid rafts are central in many transmembrane signaling pathways (including mTOR) and changes in raft cholesterol content affect their ord... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - April 20, 2024 Category: Lipidology Authors: Clifford Lingwood Tags: Hypothesis Source Type: research

Dose-response associations of triglyceride to high-density lipoprotein cholesterol ratio and triglyceride –glucose index with arterial stiffness risk
The triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio and triglyceride-glucose (TyG) index are novel indexes for insulin resistance (IR). We aimed to evaluate associations of TG/HDL-C and T... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - April 20, 2024 Category: Lipidology Authors: Wenkai Zhang, Weifeng Huo, Huifang Hu, Tianze Li, Lijun Yuan, Jinli Zhang, Yifei Feng, Yuying Wu, Xueru Fu, Yamin Ke, Mengmeng Wang, Longkang Wang, Yaobing Chen, Yajuan Gao, Xi Li, Liang Sun & hellip; Tags: Research Source Type: research

L-shaped association between lean body mass to visceral fat mass ratio with hyperuricemia: a cross-sectional study
Insufficient attention has been given to examining the correlation between body composition and hyperuricemia, leading to inconsistent findings. The primary objective of this research is to explore the associa... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - April 20, 2024 Category: Lipidology Authors: Longti Li, Ya Shao, Huiqin Zhong, Yu Wang, Rong Zhang, Boxiong Gong and Xiaoxv Yin Tags: Research Source Type: research

Can essential fatty acids (EFAs) prevent and ameliorate post-COVID-19 long haul manifestations?
It is hypothesized that COVID-19, post-COVID and post-mRNA COVID-19 (and other related) vaccine manifestations including “long haul syndrome” are due to deficiency of essential fatty acids (EFAs) and dysregula... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - April 19, 2024 Category: Lipidology Authors: Undurti N. Das Tags: Review Source Type: research

Identification and validation of biomarkers related to lipid metabolism in osteoarthritis based on machine learning algorithms
Osteoarthritis and lipid metabolism are strongly associated, although the precise targets and regulatory mechanisms are unknown. (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - April 18, 2024 Category: Lipidology Authors: Hang Li, Yubao Cui, Jian Wang, Wei Zhang, Yuhao Chen and Jijun Zhao Tags: Research Source Type: research

Blood lipids mediate the effects of gut microbiome on endometriosis: a mendelian randomization study
There is evidence for an association between the gut microbiome and endometriosis. However, their causal relationship and the mediating role of lipid metabolism remain unclear. (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - April 16, 2024 Category: Lipidology Authors: Chang Su, Su Wan, Jin Ding, Guantai Ni and Huafeng Ding Tags: Research Source Type: research

Triglyceride-glucose index predicts postoperative delirium in elderly patients with type 2 diabetes mellitus: a retrospective cohort study
Postoperative delirium (POD) is more prevalent among elderly patients with type 2 diabetes mellitus (T2DM). Insulin resistance (IR) can be assessed using the triglyceride-glucose (TyG) index, a novel biomarker... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - April 15, 2024 Category: Lipidology Authors: Miao Sun, Min Liu, Faqiang Zhang, Lijuan Sang, Yuxiang Song, Peng Li, Siyuan Liu, Huikai Yang, Libin Ma, Jiangbei Cao, Weidong Mi and Yulong Ma Tags: Research Source Type: research

Effect of oesophagectomy on lipid profiles in patients with oesophageal cancer combined with hyperlipidaemia: a retrospective study
Surgery is widely regarded as a pivotal therapeutic approach for treating oesophageal cancer, and clinical observations have revealed that many oesophageal cancer patients also present with concomitant hyperli... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - April 15, 2024 Category: Lipidology Authors: Jingrong Yang, Yaxin Li, Jialei Huang, Jiabin Lai, Xiangrui Chen, Wenxuan Xia and Yu Wang Tags: Research Source Type: research

The impact of lipidome on breast cancer: a Mendelian randomization study
This study aims to investigate the association between specific lipidomes and the risk of breast cancer (BC) using the Two-Sample Mendelian Randomization (TSMR) approach and Bayesian Model Averaging Mendelian ... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - April 15, 2024 Category: Lipidology Authors: Yuchen Cao, Meichen Ai and Chunjun Liu Tags: Research Source Type: research

Increased visceral fat area to skeletal muscle mass ratio is positively associated with the risk of metabolic dysfunction-associated steatotic liver disease in a Chinese population
The diagnosis and comprehension of nonalcoholic fatty liver disease (NAFLD), recently redefined as metabolic dysfunction-associated steatotic liver disease (MASLD) are gaining a better understanding. In this s... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - April 14, 2024 Category: Lipidology Authors: Chenbing Liu, Nan Li, Di Sheng, Yahong Shao, Lihong Qiu, Chao Shen and Zhong Liu Tags: Research Source Type: research