Journal of the Neurological Sciences This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Adalimumab as treatment for neurosarcoidosis: A case series
Sarcoidosis is a disease characterized by non-caseating granulomas that can involve the central nervous system as neurosarcoidosis. This challenging disease is currently managed with high dose steroids, and sometimes the addition of infliximab. Other TNA-alpha inhibitors have not been studied as rigorously. We discovered ten neurosarcoidosis patients who were on an alternative TNA-alpha inhibitor, adalimumab. Eight patients had a positive response clinically and radiographically to adalimumab. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - April 15, 2024 Category: Neurology Authors: Jeffrey Shen, Megumi Sugita, Andrea Linares-Lopez, Suma Shah, Christopher Eckstein, Elijah Lackey Tags: Clinical short communication Source Type: research

Editorial Board
(Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - April 13, 2024 Category: Neurology Source Type: research

Serum Neurofilament light chain, inflammatory markers, and kynurenine metabolites in patients with persistent post-concussion symptoms: A cohort study
This study aims to investigate these biomarkers in PPCS patients, elucidating their relevance in the prolonged phase of concussion. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - April 13, 2024 Category: Neurology Authors: Peter Preben Eggertsen, Johan Palmfeldt, Asger Roer Pedersen, Oana-Veronica Frederiksen, Rikke Katrine Jentoft Olsen, J ørgen Feldbæk Nielsen Source Type: research

Clinical and genetic features of dominant Essential Tremor in Tuscany, Italy: FUS, CAMTA1, ATXN1 and beyond
Essential Tremor (ET) is one of the most common neurological disorders. In most instances ET is inherited as an autosomal dominant trait with age-related penetrance (virtually complete in advanced age); however, ET genetics remains elusive. The current study aims to identify possibly pathogenic genetic variants in a group of well-characterized ET families. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - April 12, 2024 Category: Neurology Authors: D. Orsucci, A. Tessa, E. Caldarazzo Ienco, R. Trovato, G. Natale, G. Bilancieri, M. Giuntini, A. Napolitano, S. Salvetti, M. Vista, F.M. Santorelli Tags: Clinical short communication Source Type: research

Clinical significance of intracranial hemorrhage after thrombectomy detected solely by magnetic resonance imaging and not by computed tomography
This study investigated the clinical features of ICH after MT detected solely by MRI. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - April 12, 2024 Category: Neurology Authors: Kentaro Suzuki, Takehiro Katano, Shinichiro Numao, Yuji Nishi, Akihito Kutsuna, Takuya Kanamaru, Tomonari Saito, Junya Aoki, Yasuhiro Nishiyama, Kazumi Kimura Source Type: research

The search for blood-biomarkers of persistent post-concussion symptoms
Prolonged symptoms following concussion, commonly called persistent post-concussion symptoms (PPCS), are a major public health burden that occur in up to an estimated 30% of all individuals that experience a concussion (a form of mild traumatic brain injury; mTBI) [1]. Despite this prevalence, the underlying pathophysiology and mechanism of PPCS are still unknown. This lack of knowledge significantly impairs clinician's abilities to identify patients at risk for developing PPCS and objectively monitor patients with PPCS and has also prevented development of therapeutics to reduce symptoms and thus limit the significant per...
Source: Journal of the Neurological Sciences - April 12, 2024 Category: Neurology Authors: Timothy B. Meier Source Type: research

Corrigendum to “Incorporating health equity in the neurology curriculum: Our experience” [Journal of the Neurological Science (2023) 120665]
The authors regret that we neglected to include LaShyra Nolen as an author. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - April 11, 2024 Category: Neurology Authors: Tamara B. Kaplan, Christopher Doughty, LaShyra Nolan, Joshua Budhu Source Type: research

Body representation after a stroke in the brainstem
The objective of this study was to determine the effects of a brainstem stroke on body representation in horizontal and frontal plane, and links with impaired posture and neuroanatomy. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - April 11, 2024 Category: Neurology Authors: Chlo é Émard-Lamy, Laura Bergé, Arnaud Saj Tags: Clinical short communication Source Type: research

Comparative analysis of energy expenditure and costs in neuroimaging
Over the past several years there has been a growing awareness of energy usage in industrial and household devices, leading to the adoption of both energy-saving modes as well as implementation of regulations to set energy efficiency standards [1,4]. Despite strides in energy efficiency in the residential and office sectors, the healthcare sector has lagged in implementation of similar initiatives [1]. One such area that has seen a rapid increase in healthcare-associated energy usage and spending without a focus on resource saving initiatives is the use of advanced imaging like CT and MRI [1]. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - April 11, 2024 Category: Neurology Authors: William J. Signorile, Amit Mahajan, Robert K. Fulbright, Adeel S. Zubair Source Type: research

Neurological advocacy: Empowering the next generation of neurologists
In light of last month's publication of the Global Burden of Neurological Disease [1], and in consideration of the 2022 WHO Intersectoral Global Action Plan (IGAP) [2,3], the mandate to act on neurological disorders has never been greater. The World Federation of Neurology has just published twelve recommendations on strengthening neurological advocacy: the way of transitioning from evidence to action [4]. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - April 11, 2024 Category: Neurology Authors: Arina A. Tamborska, Justin T. Jordan, Benedict D. Michael, Mayowa O. Owolabi Source Type: research

Use of the concussion check protocol for concussion assessment in a female soccer team over two consecutive seasons in New Zealand
Address deficiencies in access to sports sideline medical care by using a Concussion Check Protocol (CCP) for non-medically-trained people. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - April 10, 2024 Category: Neurology Authors: D. King, P.A. Hume, T.N. Clark, J.V. Wethe Source Type: research

Favorable prognosis in posterior circulation ischemic stroke: Insights from a nationwide stroke databank
This study aimed to comprehensively assess the clinical characteristics and outcomes of PCIS patients compared to those with anterior circulation ischemic stroke (ACIS). (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - April 9, 2024 Category: Neurology Authors: Masaomi Koyanagi, Taketo Hatano, Michikazu Nakai, Takenori Ogura, Kazuo Minematsu, Shotai Kobayashi, Kazunori Toyoda, for the Japan Stroke Data Bank Investigators Source Type: research

Endovascular thrombectomy for large ischemic strokes: An updated living systematic review and meta-analysis of randomized clinical trials
Recent studies indicate endovascular thrombectomy (EVT) as a safe, effective treatment for acute ischemic stroke (AIS) with large ischemic regions. Our study updates an ongoing living systematic review and meta-analysis of randomized controlled trials (RCTs) comparing outcomes of EVT to medical management only. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - April 8, 2024 Category: Neurology Authors: Rami Z. Morsi, Mohamed Elfil, Hazem S. Ghaith, Mohammad Aladawi, Ahmed Elmashad, Sachin Kothari, Harsh Desai, Sherief Ghozy, Shyam Prabhakaran, Krishna Amuluru, Chirag D. Gandhi, Tareq Kass-Hout, Fawaz Al-Mufti Tags: Review Article Source Type: research

Data-driven subtypes of mixed semantic-logopenic primary progressive aphasia: Linguistic features, biomarker profiles and brain metabolic patterns
In this study, we enrolled 55 patients diagnosed with PPA, comprising 12 semantic variant (svPPA), 23 logopenic variant (lvPPA), and 20 mPPA cases with linguistic characteristics consistent with both svPPA and lvPPA (s/lvPPA). All patients underwent language assessments, evaluation of Alzheimer's disease biomarkers (via cerebrospinal fluid analysis or Amyloid-PET), and 18F-FDG-PET brain scans. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - April 5, 2024 Category: Neurology Authors: Salvatore Mazzeo, Carmen Morinelli, Cristina Polito, Giulia Giacomucci, Valentina Moschini, Assunta Ingannato, Juri Balestrini, Daniele Frigerio, Filippo Emiliani, Giulia Galdo, Chiara Crucitti, Diletta Piazzesi, Silvia Bagnoli, Sonia Padiglioni, Valentin Source Type: research

Are physical activity levels, cardiorespiratory fitness and peak power associated with Parkinson's disease severity?
The objectives of the, present study were to assess associations between PA, cardiorespiratory fitness (VO2-, max), and muscle peak power and measures of the Movement Disorder Societysponsored, revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS), the Parkinson's disease questionnaire-39 (PDQ-39), and the four PD hallmark motor, symptoms (rigidity, bradykinesia, postural instability, and tremor). (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - April 5, 2024 Category: Neurology Authors: Frederik Bonde-Jensen, Ulrik Dalgas, Martin Langeskov-Christensen Source Type: research