List of Reviewers
(Source: Journal of Radiation Research)
Source: Journal of Radiation Research - December 2, 2016 Category: Physics Tags: List of reviewers Source Type: research
A study on a dental device for the prevention of mucosal dose enhancement caused by backscatter radiation from dental alloy during external beam radiotherapy
The changes in dose distribution caused by backscatter radiation from a common commercial dental alloy (Au–Ag–Pd dental alloy; DA) were investigated to identify the optimal material and thicknesses of a dental device (DD) for effective prevention of mucositis. To this end, 1 cm3 of DA was irradiated with a 6-MV X-ray beam (100 MU) in a field size of 10 x 10 cm2 using a Novalis TX linear accelerator. Ethylene vinyl acetate copolymer, polyolefin elastomer, and polyethylene terephthalate (PET) were selected as DD materials. The depth dose along the central axis was determined with respect ...
Source: Journal of Radiation Research - December 2, 2016 Category: Physics Authors: Katsura, K., Utsunomiya, S., Abe, E., Sakai, H., Kushima, N., Tanabe, S., Yamada, T., Hayakawa, T., Yamanoi, Y., Kimura, S., Wada, S., Aoyama, H., Hayashi, T. Tags: Short communication Source Type: research
Follow-up and evaluation of the pregnancy outcome in women of reproductive age with Graves disease after 131Iodine treatment
The aims of the present study were to analyze the outcomes of pregnancy, after 131I treatment, in patients of reproductive age with Graves’ hyperthyroidism and to investigate the effects, if any, of the 131I treatment on the mothers and newborns. From 2009 to 2014, 257 pregnant female patients with Graves’ hyperthyroidism in the outpatients at the Department of Nuclear Medicine and 166 healthy pregnant women from the Department of Obstetrics at Sun Yat-Sen Memorial Hospital were included in our study. They were divided into a 131I therapy group (n = 130) and an anti-thyroid drug (ATD) group (n =&...
Source: Journal of Radiation Research - December 2, 2016 Category: Physics Authors: Zhang, L.-H., Li, J.-Y., Tian, Q., Liu, S., Zhang, H., Liu, S., Liang, J.-G., Lu, X.-P., Jiang, N.-Y. Tags: Regular paper Source Type: research
Evaluation of the radiobiological gamma index with motion interplay in tangential IMRT breast treatment
The purpose of this study was to evaluate the impact of the motion interplay effect in early-stage left-sided breast cancer intensity-modulated radiation therapy (IMRT), incorporating the radiobiological gamma index (RGI). The IMRT dosimetry for various breathing amplitudes and cycles was investigated in 10 patients. The predicted dose was calculated using the convolution of segmented measured doses. The physical gamma index (PGI) of the planning target volume (PTV) and the organs at risk (OAR) was calculated by comparing the original with the predicted dose distributions. The RGI was calculated from the PGI using the tumo...
Source: Journal of Radiation Research - December 2, 2016 Category: Physics Authors: Sumida, I., Yamaguchi, H., Das, I. J., Kizaki, H., Aboshi, K., Tsujii, M., Yamada, Y., Tamari, K., Suzuki, O., Seo, Y., Isohashi, F., Yoshioka, Y., Ogawa, K. Tags: Regular paper Source Type: research
Carbon-ion radiotherapy for locally advanced cervical cancer with bladder invasion
In this study, C-ion RT showed favorable local control with reasonable toxicities, but the results were still unsatisfactory. We have the expectation of improvement of therapeutic effects by using C-ion RT with concurrent chemotherapy. (Source: Journal of Radiation Research)
Source: Journal of Radiation Research - December 2, 2016 Category: Physics Authors: Shiba, S., Wakatsuki, M., Kato, S., Ohno, T., Okonogi, N., Karasawa, K., Kiyohara, H., Tsujii, H., Nakano, T., Kamada, T., Shozu, M., The Working Group of the Gynecological Tumor Tags: Regular paper Source Type: research
Investigation of whether in-room CT-based adaptive intracavitary brachytherapy for uterine cervical cancer is robust against interfractional location variations of organs and/or applicators
This study investigates whether in-room computed tomography (CT)-based adaptive treatment planning (ATP) is robust against interfractional location variations, namely, interfractional organ motions and/or applicator displacements, in 3D intracavitary brachytherapy (ICBT) for uterine cervical cancer. In ATP, the radiation treatment plans, which have been designed based on planning CT images (and/or MR images) acquired just before the treatments, are adaptively applied for each fraction, taking into account the interfractional location variations. 2D and 3D plans with ATP for 14 patients were simulated for 56 fractions at a ...
Source: Journal of Radiation Research - December 2, 2016 Category: Physics Authors: Oku, Y., Arimura, H., Nguyen, T. T. T., Hiraki, Y., Toyota, M., Saigo, Y., Yoshiura, T., Hirata, H. Tags: Regular paper Source Type: research
Dose-volume analysis of predictors for chronic gastrointestinal complications in patients with cervical cancer treated with postoperative concurrent chemotherapy and whole-pelvic radiation therapy
In conclusion, the small bowel loops are better predictors of chronic GI complications compared with the bowel bag, and a relatively high-dose volume (e.g. V40) of the small bowel loops is a useful predictor of chronic GI complications. (Source: Journal of Radiation Research)
Source: Journal of Radiation Research - December 2, 2016 Category: Physics Authors: Isohashi, F., Mabuchi, S., Akino, Y., Yoshioka, Y., Seo, Y., Suzuki, O., Tamari, K., Yoshino, K., Sawada, K., Ueda, Y., Kobayashi, E., Sumida, I., Mizuno, H., Okubo, H., Kimura, T., Ogawa, K. Tags: Regular paper Source Type: research
Accuracy evaluation of a 3D-printed individual template for needle guidance in head and neck brachytherapy
To transfer the preplan for the head and neck brachytherapy to the clinical implantation procedure, a preplan-based 3D-printed individual template for needle insertion guidance had previously been designed and used. The accuracy of needle insertion using this kind template was assessed in vivo. In the study, 25 patients with head and neck tumors were implanted with 125I radioactive seeds under the guidance of the 3D-printed individual template. Patients were divided into four groups based on the site of needle insertion: the parotid and masseter region group (nine patients); the maxillary and paranasal region group (eight ...
Source: Journal of Radiation Research - December 2, 2016 Category: Physics Authors: Huang, M.-W., Zhang, J.-G., Zheng, L., Liu, S.-M., Yu, G.-Y. Tags: Regular paper Source Type: research
Metabolic tumor volume on FDG-PET/CT is a possible prognostic factor for Stage I lung cancer patients treated with stereotactic body radiation therapy: a retrospective clinical study
The aim of this study was to determine whether metabolic tumor volume (MTV) and total lesion glycolysis (TLG) are associated with outcomes in Stage I lung cancer patients treated with stereotactic body radiation therapy (SBRT). Thirty-eight patients underwent [18F] fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG-PET/CT) within 60 days before SBRT at our institution between January 2001 and December 2011. The maximum standardized uptake value (SUVmax), MTV2, MTV4, MTV6, TLG40%, TLG50% and TLG60% were calculated. Prognostic factors for overall survival (OS) and local control (LC) were analyzed us...
Source: Journal of Radiation Research - December 2, 2016 Category: Physics Authors: Takahashi, N., Yamamoto, T., Matsushita, H., Sugawara, T., Kubozono, M., Umezawa, R., Ishikawa, Y., Kozumi, M., Katagiri, Y., Tasaka, S., Takeda, K., Takeda, K., Dobashi, S., Jingu, K. Tags: Regular paper Source Type: research
Characterization of histone modifications associated with DNA damage repair genes upon exposure to gamma rays in Arabidopsis seedlings
Dynamic histone modifications play an important role in controlling gene expression in response to various environmental cues. This mechanism of regulation of gene expression is important for sessile organisms, like land plants. We have previously reported consistent upregulation of various marker genes in response to gamma rays at various post-irradiation times. In the present study, we performed various chromatin modification analyses at selected loci using the standard chromatin immunoprecipitation procedure, and demonstrate that upregulation of these genes is associated with histone H3 lysine 4 tri-methylation (H3K4me3...
Source: Journal of Radiation Research - December 2, 2016 Category: Physics Authors: Mondal, S., Go, Y. S., Lee, S. S., Chung, B. Y., Kim, J.-H. Tags: Regular paper Source Type: research
Dosimetric impact of an air passage on intraluminal brachytherapy for bronchus cancer
This study indicates the need for improvement in dose calculation accuracy with respect to intraluminal brachytherapy for bronchus cancer. (Source: Journal of Radiation Research)
Source: Journal of Radiation Research - December 2, 2016 Category: Physics Authors: Okamoto, H., Wakita, A., Nakamura, S., Nishioka, S., Aikawa, A., Kato, T., Abe, Y., Kobayashi, K., Inaba, K., Murakami, N., Itami, J. Tags: Regular paper Source Type: research
The effects of a 50-Hz magnetic field on the cardiovascular system in rats
This study was conducted to explore the effects of long-term exposure to a 50-Hz MF on the cardiovascular system. In the study, an exposure system was constructed, and the distribution of the 50-Hz MF was determined. Sixty-four Sprague-Dawley (SD) rats were exposed to a 50-Hz MF at 100 μT for 24 weeks, 20 h per day, while another 64 rats were sham exposed. During the exposure, blood pressure was measured every 4 weeks. After 24 weeks, echocardiography, cardiac catheterization and electrocardiography were performed. Moreover, heart and body weight were recorded, and haematoxylin–eosin staining and real-time PC...
Source: Journal of Radiation Research - December 2, 2016 Category: Physics Authors: Zhou, L., Wan, B., Liu, X., Zhang, Y., Lai, J., Ruan, G., He, M., Chen, C., Wang, D. W. Tags: Regular paper Source Type: research
Effects of combined radiofrequency field exposure on amyloid-beta-induced cytotoxicity in HT22 mouse hippocampal neurones
In this study, we examined the effect of combined RF radiation on amyloid-beta (Aβ)–induced cytotoxicity in HT22 rat hippocampal neurons. Treatment with Aβ suppressed HT22 cell proliferation in a concentration-dependent manner. RF exposure did not affect cell proliferation, and also had a marginal effect on Aβ-induced suppression of growth in HT22 cells. Cell cycle analysis showed that Aβ decreased the G1 fraction and increased the subG1 fraction, indicating increased apoptosis. Accordingly, Aβ increased the annexin V/propidium iodide (PI)–positive cell fraction and the degradation of p...
Source: Journal of Radiation Research - December 2, 2016 Category: Physics Authors: Lee, J.-S., Kim, J.-Y., Kim, H.-J., Kim, J. C., Lee, J.-S., Kim, N., Park, M.-J. Tags: Regular paper Source Type: research
Chronic exposure of adult, postnatal and in utero rat models to low-dose 137Cesium: impact on circulating biomarkers
This study showed that response profiles differed according to age at exposure: lipid metabolism was most radiosensitive in the postnatal model, and steroid hormone metabolism was most radiosensitive in rats exposed in adulthood. There was no evidence of deleterious effects suggesting a potential impact on fertility or procreation. (Source: Journal of Radiation Research)
Source: Journal of Radiation Research - December 2, 2016 Category: Physics Authors: Manens, L., Grison, S., Bertho, J.-M., Lestaevel, P., Gueguen, Y., Benderitter, M., Aigueperse, J., Souidi, M. Tags: Regular paper Source Type: research
Dependence and independence of survival parameters on linear energy transfer in cells and tissues
Carbon-ion radiotherapy has been used to treat more than 9000 cancer patients in the world since 1994. Spreading of the Bragg peak is necessary for carbon-ion radiotherapy, and is designed based on the linear–quadratic model that is commonly used for photon therapy. Our recent analysis using in vitro cell kills and in vivo mouse tissue reaction indicates that radiation quality affects mainly the alpha terms, but much less the beta terms, which raises the question of whether this is true in other biological systems. Survival parameters alpha and beta for 45 in vitro mammalian cell lines were obtained by colony formati...
Source: Journal of Radiation Research - December 2, 2016 Category: Physics Authors: Ando, K., Goodhead, D. T. Tags: Regular paper Source Type: research
