Lateral cartilage defects and medial subchondral surface ratio are associated with knee ‐related disability
This article i s protected by copyright. All rights reserved (Source: Journal of Orthopaedic Research)
Source: Journal of Orthopaedic Research - November 27, 2018 Category: Orthopaedics Authors: Joshua S. Everhart,
Moneer M. Abouljoud,
David C. Flanigan Tags: Research Article Source Type: research
Biomimetic Proteoglycans can Molecularly Engineer Early Osteoarthritic Cartilage in vivo
This article is protected by copyright. All rights reserved (Source: Journal of Orthopaedic Research)
Source: Journal of Orthopaedic Research - November 27, 2018 Category: Orthopaedics Authors: Evan R. Phillips,
Katsiaryna Prudnikova,
Tuan Bui,
Adam J. Taylor,
Diego A. Galindo,
Richard B. Huneke,
J. Steve Hou,
Mary K. Mulcahey,
Michele S. Marcolongo Tags: Research Article Source Type: research
Impaired bone healing following treatment of established nonunion correlates with serum cytokine expression
This article is protected by copyright. All rights re served (Source: Journal of Orthopaedic Research)
Source: Journal of Orthopaedic Research - November 27, 2018 Category: Orthopaedics Authors: Albert Cheng,
Laxminarayanan Krishnan,
Pallab Pradhan,
Laura D. Weinstock,
Levi B. Wood,
Krishnendu Roy,
Robert E. Guldberg Tags: Research Article Source Type: research
Molecular and Histological Characteristics of Bovine Caudal Nucleus Pulposus by Combined Changes in Hydrostatic and Osmotic Pressures in vitro
This article is protected by copyright. All rights reserved (Source: Journal of Orthopaedic Research)
Source: Journal of Orthopaedic Research - November 27, 2018 Category: Orthopaedics Authors: Shuichi Mizuno,
Kaori Kashiwa,
James D. Kang Tags: Research Article Source Type: research
Biomechanical Evaluation of Tendon Regeneration with Adipose ‐derived Stem Cell
AbstractThe use of Adipose ‐Derived Stem Cells (ADSC) has been presented as a new alternative for tendon reconstruction. Have been admitted that ADSCs are related to better outcomes when used in tendon healing. This research was designed to apply the potential of ADSCs in tendon healing. Flexor digitorum superficialis tendo n lesion was performed on both legs of eleven New Zealand rabbits and them, at the same time, treated as follows: suture alone (Group III – Suture, n:10), suture associated with ADSC (Group IV – Suture + ADSC, n:10) or without suture (Group II – SHAN, n:2). At four weeks after the tendon s u...
Source: Journal of Orthopaedic Research - November 26, 2018 Category: Orthopaedics Authors: Alex Lima Santos,
Camila Gonzaga da Silva,
Leticia Siqueira S á Barretto,
Carlos Eduardo da Silveira Franciozi,
Marcel Jun Sugawara Tamaoki,
Fernando Gonçalves de Almeida,
Flavio Faloppa Tags: Special Issue Review Source Type: research
Mechanical properties of a hierarchical electrospun scaffold for ovine anterior cruciate ligament replacement
AbstractThe anterior cruciate ligament (ACL) acts to stabilize the knee and prevent excessive motion of the tibia relative to the femur. Tears of the ACL are common and can result in pain and damage to surrounding tissues. Thus a torn ACL is often surgically replaced with an autograft or allograft material. Drawbacks to clinically available ACL grafts motivate the development of a tissue engineered ACL replacement. Our group has previously developed a polycaprolactone electrospun scaffold that mimics the hierarchical structure of the ACL. The goal of this study was to investigate the mechanical properties of the electrospu...
Source: Journal of Orthopaedic Research - November 26, 2018 Category: Orthopaedics Authors: Hannah Pauly,
Daniel Kelly,
Ketul Popat,
Jeremiah Easley,
Ross Palmer,
Tammy L. Haut Donahue Tags: Research Article Source Type: research
Microplate Assay for Denatured Collagen using Collagen Hybridizing Peptides
ABSTRACTThe purpose of this study was to develop a microplate assay for quantifying denatured collagen by measuring the fluorescence of carboxyfluorescein bound collagen hybridizing peptides (F ‐CHP). We have shown that F‐CHP binds selectively with denatured collagen, and that mechanical overload of tendon fascicles causes collagen denaturation. Proteinase K was used to homogenize tissue samples after F‐CHP staining, allowing fluorescence measurement using a microplate reader. We com pared our new assay to our previous image analysis method and the trypsin‐hydroxyproline assay, which is the only other available met...
Source: Journal of Orthopaedic Research - November 26, 2018 Category: Orthopaedics Authors: Allen H. Lin,
Jared L. Zitnay,
Yang Li,
S. Michael Yu,
Jeffrey A. Weiss Tags: Research Article Source Type: research
Predictors of fracture healing in patients with recalcitrant nonunions treated with autologous culture expanded bone marrow ‐derived mesenchymal stromal cells
AbstractThe study reports the prospective outcome of treating severe recalcitrant fracture nonunion in patients with autologous bone marrow ‐derived mesenchymal stromal cells (BMSC) from 2003‐2010 and analyse predictors of union. Autologous BMSC were culture expanded and inserted at nonunion site with or without carriers in addition to surgical stabilisation of the fracture. Radiological union was ascertained by musculoskeletal radi ologists on plain radiographs and/or CT scans. A logistic regression analysis was performed with cell‐expansion parameters (cell numbers, cell doubling time) and known clinical factors (e...
Source: Journal of Orthopaedic Research - November 26, 2018 Category: Orthopaedics Authors: Atanu Bhattacharjee,
Jan H Kuiper,
Sally Roberts,
Paul E Harrison,
Victor N Cassar ‐Pullicino,
Bernhard Tins,
Stephan Bajada,
James B Richardson Tags: Special Issue Research Article Source Type: research
Radiological evaluation of kyphoplasty with an intravertebral expander after osteoporotic vertebral fracture
This article is protected by copyright. All rights reserved (Source: Journal of Orthopaedic Research)
Source: Journal of Orthopaedic Research - November 20, 2018 Category: Orthopaedics Authors: Mohammad Arabmotlagh,
Sabrina Christina Nikoleiski,
Sven Schmidt,
Michael Rauschmann,
Marcus Rickert,
Christoph Fleege Tags: Research Article Source Type: research
Full ‐Thickness Rotator Cuff Tear In Rat Results In Distinct Temporal Expression Of Multiple Proteases In Tendon, Muscle, And Cartilage
This article is protected by copyright. All rights reserved (Source: Journal of Orthopaedic Research)
Source: Journal of Orthopaedic Research - November 20, 2018 Category: Orthopaedics Authors: Elda A. Trevi ño,
Jennifer McFaline‐Figueroa,
Robert E. Guldberg,
Manu O. Platt,
Johnna S. Temenoff Tags: Research Article Source Type: research
Medially ‐Stabilized Total Knee Arthroplasty Does Not Alter Knee Laxity and Balance in Cadaveric Knees
This article is protected by c opyright. All rights reserved (Source: Journal of Orthopaedic Research)
Source: Journal of Orthopaedic Research - November 20, 2018 Category: Orthopaedics Authors: Rachel K. Baker,
Joseph A. Ewing,
Matthew D. Beal,
David W. Manning,
Robert A. Siston Tags: Research Article Source Type: research
Novel model for the induction of postnatal murine hip deformity
ABSTRACTAcetabular dysplasia is a common, multi ‐etiological, pre‐osteoarthritic (OA) feature that can lead to pain and instability of the young adult hip. Despite the clinical significance of acetabular dysplasia, there is a paucity of small animal models to investigate structural and functional changes that mediate morphology of the dysplas tic hip and drive the subsequent OA cascade. Utilizing a novel murine model developed in our laboratory, this study investigated the role of surgically induced unilateral instability of the postnatal hip on the initiation and progression of acetabular dysplasia and impingement up ...
Source: Journal of Orthopaedic Research - November 19, 2018 Category: Orthopaedics Authors: Megan L. Killian,
Ryan C. Locke,
Michael G. James,
Penny R. Atkins,
Andrew E. Anderson,
John C. Clohisy Tags: Research Article Source Type: research
Method for quantitative assessment of acetabular bone defects
This study showed the feasibility of a quantitative assessment of acetabular bone defects using a statistical shape model‐based reconstruction method. Validation results showed acceptable reconstruction accuracy, also when less h ealthy bone remains. The method could potentially be used for implant development, pre‐clinical testing, pre‐operative planning, and intra‐operative navigation. © 2018 The Authors.Journal of Orthopaedic Research® Published by Wiley Periodicals, Inc. on behalf of Orthopaedic Research Society. J Orthop Res 9999:1–9, 2018. (Source: Journal of Orthopaedic Research)
Source: Journal of Orthopaedic Research - November 19, 2018 Category: Orthopaedics Authors: Georg Hettich,
Ronja A. Schierjott,
Heiko Ramm,
Heiko Graichen,
Volkmar Jansson,
Maximilian Rudert,
Francesco Traina,
Thomas M. Grupp Tags: Research Article Source Type: research
Gene Expression in Hip Soft Tissues in Incipient Canine Hip Dysplasia and Osteoarthritis
This article is protected by copyright. All rights reserved (Source: Journal of Orthopaedic Research)
Source: Journal of Orthopaedic Research - November 19, 2018 Category: Orthopaedics Authors: Rory J Todhunter,
Susan J. Garrison,
Julie Jordan,
Linda Hunter,
Marta G. Castelhano,
Kristian Ash,
Vicki Meyers ‐Wallen,
Ursula Krotscheck,
Jessica J Hayward,
Jennifer Grenier Tags: Research Article Source Type: research
Variations in contents of hyaluronan in the peritumoral micro ‐environment of human chondrosarcoma
This article is protected by copyright. All rights reserved (Source: Journal of Orthopaedic Research)
Source: Journal of Orthopaedic Research - November 15, 2018 Category: Orthopaedics Authors: Caterina Fede,
Carla Stecco,
Andrea Angelini,
Chenglei Fan,
Elisa Belluzzi,
Assunta Pozzuoli,
Pietro Ruggieri,
Raffaele De Caro Tags: Research Article Source Type: research
