Reply to ‘Night-time blood pressure definition and target organ damage: the dark side of the moon’
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - November 6, 2022 Category: Cardiology Tags: CORRESPONDENCES Source Type: research

Night-time blood pressure definition and target organ damage: the dark side of the moon
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - November 6, 2022 Category: Cardiology Tags: CORRESPONDENCES Source Type: research

Reproducibility of sequential ambulatory blood pressure and pulse wave velocity measurements in normotensive and hypertensive individuals
Conclusion: The variability of single ABPM measurements will still yield considerable uncertainty regarding true average pressures, potentially resulting in misclassification of hypertensive status and incorrect treatment regimes. Repeated ABPM may be necessary to refine antihypertensive therapy. (Source: Journal of Hypertension)
Source: Journal of Hypertension - November 6, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research

Visit-to-visit SBP variability and risk of atrial fibrillation in middle-aged and older populations
Conclusion: Increased visit-to-visit variability of SBP is a strong predictor of incident atrial fibrillation in middle-aged and older population. Evaluation of long-term SBP variability could help to identify individuals at higher risk of atrial fibrillation. (Source: Journal of Hypertension)
Source: Journal of Hypertension - November 6, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research

Patterns and predictors of elevated blood pressure and hypertension among primary school children in urban Kenya
Conclusion: These results increase our understanding BP patterns and determinants among school children in Kenya and can help inform noncommunicable disease prevention efforts. (Source: Journal of Hypertension)
Source: Journal of Hypertension - November 6, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research

Angiotensin II prompts heart cell apoptosis via AT1 receptor-augmented phosphatase and tensin homolog and miR-320-3p functions to enhance suppression of the IGF1R-PI3K-AKT survival pathway
Conclusion: Hence, we speculate that the Ang II-AT1 receptor axis induces both phosphatase and tensin homolog and miR-320-3p expression to downregulate the IGF1R-PI3K-AKT survival pathway and cause cell apoptosis in the heart. (Source: Journal of Hypertension)
Source: Journal of Hypertension - November 6, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research

Artificial intelligence-based opportunistic screening for the detection of arterial hypertension through ECG signals
Conclusion: Our machine learning algorithm is effective in the detection of hypertension in patients using ECG-derived and basic anthropometric criteria. Our findings open new horizon in the detection of many undiagnosed hypertensive individuals who have an increased CVD risk. (Source: Journal of Hypertension)
Source: Journal of Hypertension - November 6, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research

Predictive model of hypertension resolution after adrenalectomy in primary aldosteronism: the SPAIN-ALDO score
Purpose: To develop a predictive model of hypertension resolution after adrenalectomy in patients with primary aldosteronism (PA), based on their presurgical characteristics. Methods: A retrospective multicenter study of PA patients in follow-up in 20 Spanish tertiary hospitals between 2018 and 2021 was performed (SPAIN-ALDO Register). Clinical response postadrenalectomy was classified according to the primary aldosteronism surgical outcome (PASO) consensus criteria. The predictive model was developed using a multivariate logistic regression model with the estimation of all possible equations. Results: A ...
Source: Journal of Hypertension - November 6, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research

Antihypertensive therapy of late arterial hypertension in children following successful coarctation correction
Conclusion: High prevalence of uncontrolled AH despite successful CoA repair and use of relatively low doses of antihypertensive drugs indicates the need of close blood pressure monitoring and more intensive and combined antihypertensive therapy. (Source: Journal of Hypertension)
Source: Journal of Hypertension - November 6, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research

Markers of subclinical vascular damage in young adults with type 1 diabetes mellitus: the role of central blood pressure
Introduction: Type 1 diabetes mellitus (T1D) is a chronic disease leading to cardiovascular complications that can be diagnosed early as subclinical vascular damage. To prevent such damage, it is important to increase knowledge of the effects of the different cardiovascular risk factors in patients with T1D. The aim of our study was to assess possible associations between markers of subclinical arterial damage and traditional cardiovascular risk factors, with a special focus on peripheral blood pressure and central blood pressure (cBP), in a sample of young adults with T1D. Patients and methods: The study includ...
Source: Journal of Hypertension - November 6, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research

Hydroxychloroquine reduces hypertension and soluble fms-like kinase-1 in a Nω-nitro-l-arginine methyl ester-induced preeclampsia rat model
Objective: Hydroxychloroquine, a drug used for malaria and autoimmune diseases reportedly has beneficial effects against preeclampsia in pregnant women with lupus. However, its mechanism against preeclampsia remains unclear. We investigated the effect of hydroxychloroquine on an Nω-nitro-l-arginine methyl ester-induced preeclampsia rat model. Methods: Pregnant Sprague–Dawley rats were divided into four groups based on treatment (administered on gestational days 7–18): control, Nω-nitro-l-arginine methyl ester, hydroxychloroquine, and Nω-nitro-l-arginine methyl ester plus hydroxychloroquine. All animals we...
Source: Journal of Hypertension - November 6, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research

Optimal office blood pressure levels in younger (
Background: It is unclear what thresholds and targets of office blood pressure (BP) for treatment are appropriate in younger ( (Source: Journal of Hypertension)
Source: Journal of Hypertension - November 6, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research

Young South Asian women in the United Kingdom show evidence of blunted endothelium-dependent dilatation: implications for future cardiovascular disease
Conclusion: Endothelium-dependent dilatation is blunted in young South Asians, relative to white European women, especially in South Asian OH in whom NO-dependent and prostaglandin-dependent dilatation is blunted. We suggest improved diet and greater physical activity could be particularly effective in improving endothelium-dependent dilatation and reducing future CVD risk in young South Asian OH women. (Source: Journal of Hypertension)
Source: Journal of Hypertension - November 6, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research

Maximum home blood pressure and cardiovascular outcomes in patients with type 2 diabetes: KAMOGAWA-HBP study
Conclusion: Maximum home blood pressure is a predictor of subsequent cardiovascular events in patients with type 2 diabetes. (Source: Journal of Hypertension)
Source: Journal of Hypertension - November 6, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research

Association of arterial properties with left ventricular morphology and function in the community
This study aimed to characterize the association of aortic size and ePWV with LV morphology and function. Methods: The study cohort consisted of 539 participants without overt cardiac disease who underwent extensive cardiovascular examination. Aortic root diameter was measured by two-dimensional echocardiography and ePWV was calculated from a regression equation using age and mean blood pressure. LV global longitudinal strain (LVGLS) was obtained by speckle-tracking echocardiography. Results: Aortic root diameter and ePWV were correlated with LV mass index and LVGLS, while only ePWV was related to E/e′ rati...
Source: Journal of Hypertension - November 6, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research