In vivo monitoring blood ‐brain barrier permeability using spectral imaging through optical clearing skull window
This article is protected by copyright. All rights reserved. (Source: Journal of Biophotonics)
Source: Journal of Biophotonics - November 28, 2018 Category: Physics Authors: Wei Feng,
Chao Zhang,
Tingting Yu,
Oxana Semyachkina ‐Glushkovskaya,
Dan Zhu Tags: FULL ARTICLE Source Type: research
Increasing fluorescence lifetime for resolution improvement in STED nanoscopy
This article is protected by copyright. All rights reserved. (Source: Journal of Biophotonics)
Source: Journal of Biophotonics - November 28, 2018 Category: Physics Authors: Lu ‐Wei Wang,
Yue Chen,
Wei Yan,
Xiao‐Yu Weng,
Zhi‐Gang Yang,
Tong Ye,
Jun‐Le Qu Tags: FULL ARTICLE Source Type: research
Rapid discrimination of colon cancer cells with single base mutation in KRAS gene segment using laser tweezers Raman spectroscopy
This article is protected by copyright. All rights reserved. (Source: Journal of Biophotonics)
Source: Journal of Biophotonics - November 28, 2018 Category: Physics Authors: Mengmeng Liu,
Xiujie Liu,
Zufang Huang,
Xiaoqiong Tang,
Xueliang Lin,
Yunchao Xu,
Guannan Chen,
Hang Fai Kwok,
Yao Lin,
Shangyuan Feng Tags: FULL ARTICLE Source Type: research
Environment ‐specific spectral modeling: A new tool for the analysis of biological specimens
Fluorescence spectral shift induced by viscosity and/or interactions with the biological matrix is corrected to improve spectral unmixing of formalin ‐fixed paraffin embedded blocks samples. Additionally, the method can extract additional information with potential application in the field of fluorescence‐guided surgery. The proposed method, in fact, exploits fluorescence spectra variations seen by low‐resolution optical imagers used in pre clinical and clinical in vivo applications. The recent discovery of fluorescent dyes for improving pathologic tissues identification has highlighted the need of robust methods for...
Source: Journal of Biophotonics - November 26, 2018 Category: Physics Authors: Giovanni Valbusa,
Martina Capozza,
Chiara Brioschi,
Francesco Blasi,
Simona Ghiani,
Alessandro Maiocchi Tags: FULL ARTICLE Source Type: research
Indocyanine Green labeling for optical and photoacoustic imaging of Mesenchymal Stem Cells after in vivo transplantation
This article is protected by copyright. All rights reserved. (Source: Journal of Biophotonics)
Source: Journal of Biophotonics - November 24, 2018 Category: Physics Authors: M Filippi,
F Garello,
C Pasquino,
F Arena,
P Giustetto,
F Antico,
E Terreno Tags: FULL ARTICLE Source Type: research
One ‐to‐one registration of en‐face optical coherence tomography attenuation coefficients with histology of a prostatectomy specimen
This article explains the method to perform supervised automated quantitative analysis of OCT data, and the one ‐to‐one registration of OCT extracted quantitative data with histopathological outcomes.This article is protected by copyright. All rights reserved. (Source: Journal of Biophotonics)
Source: Journal of Biophotonics - November 22, 2018 Category: Physics Authors: A Swaan,
BG Muller,
LS Wilk,
M Almasian,
RAA van Kollenburg,
ECH Zwartkruis,
L Rozendaal,
DM de Bruin,
DJ Faber,
TG van Leeuwen,
MB van Herk Tags: FULL ARTICLE Source Type: research
Detection of the T cell activation state using nonlinear optical microscopy
Nonlinear microscopy imaging provides qualitative and quantitative distinction between activated and na ïve T‐lymphocytes based on the lipid body content of the cells, correlated with cholesterol and lipid spectra. The ability to monitor the activation state of T ‐cells during immunotherapy is of great importance. Although specific activation markers do exist, their abundance and complicated regulation cannot definitely define the activation state of the cells. Previous studies have shown that Third Harmonic Generation (THG) imaging could distinguish betwe en activated versus resting microglia and healthy versus cance...
Source: Journal of Biophotonics - November 19, 2018 Category: Physics Authors: Evangelia Gavgiotaki,
George Filippidis,
Ioanna Zerva,
George Kenanakis,
Emmanuel Archontakis,
Sofia Agelaki,
Vasilios Georgoulias,
Irene Athanassakis Tags: FULL ARTICLE Source Type: research
A novel urine analysis technique combining affinity chromatography with Au nanoparticle based SERS spectroscopy for potential applications in noninvasive cancer screening
This article is protected by copyright. All rights reserved. (Source: Journal of Biophotonics)
Source: Journal of Biophotonics - November 16, 2018 Category: Physics Authors: Xueliang Lin,
Lingna Wang,
Huijing Lin,
Duo Lin,
Jinyong Lin,
Xiujie Liu,
Sufang Qiu,
Yuanji Xu,
Guannan Chen,
Shangyuan Feng Tags: FULL ARTICLE Source Type: research
Development and evaluation of realistic optical cell models for rapid and label ‐free cell assay by diffraction imaging
This article is protected by copyright. All rights reserved. (Source: Journal of Biophotonics)
Source: Journal of Biophotonics - November 16, 2018 Category: Physics Authors: Shuting Wang,
Jing Liu,
Jun Q. Lu,
Wenjin Wang,
Safaa A. Al ‐Qaysi,
Yaohui Xu,
Wenhuan Jiang,
Xin‐Hua Hu Tags: FULL ARTICLE Source Type: research
Automated assessment of breast cancer margin in optical coherence tomography images via pretrained convolutional neural network
Among women, breast cancer is the second leading cause of cancer in the developing countries. The gold standard method for the evaluation of breast cancer detection involves microscopic testing of a hematoxylin and eosin (H&E) ‐stained tissue biopsy. In our study, we propose a pretrained Inception‐v3 convolutional neural network (CNN) with reverse active learning for the classification of healthy and malignancy breast tissue using optical coherence tomography (OCT) images. The present method will be helpful for real‐ time, rapid, in‐vivo, intra‐operative margin assessment over large surface areas while preserving...
Source: Journal of Biophotonics - November 13, 2018 Category: Physics Authors: Neeru Singla,
Kavita Dubey,
Vishal Srivastava Tags: FULL ARTICLE Source Type: research
Visualizing the “Sandwich” Structure of Osteocytes in Their Native Environment Deep in Bone in Vivo
This article is protected by copyright. All rights reserved. (Source: Journal of Biophotonics)
Source: Journal of Biophotonics - November 13, 2018 Category: Physics Authors: Ke Wang,
Yu Du,
Hongji Liu,
Mengyao Gan,
Shen Tong,
Wenhui Wen,
Ziwei Zhuang,
Ping Qiu Tags: FULL ARTICLE Source Type: research
Integration of Diffraction Phase Microscopy and Raman Imaging for Label ‐free Morpho‐molecular Assessment of Live Cells
This article is protected by copyright. All rights reserved. (Source: Journal of Biophotonics)
Source: Journal of Biophotonics - November 12, 2018 Category: Physics Authors: Rishikesh Pandey,
Renjie Zhou,
Rosalie Bordett,
Ciera Hunter,
Kristine Glunde,
Ishan Barman,
Tulio Valdez,
Christine Finck Tags: FULL ARTICLE Source Type: research
In vitro and in vivo phasor analysis of stoichiometry and pharmacokinetics using short lifetime near ‐infrared dyes and time‐gated imaging
This article is protected by copyright. All rights reserved. (Source: Journal of Biophotonics)
Source: Journal of Biophotonics - November 12, 2018 Category: Physics Authors: Sez ‐Jade Chen,
Nattawut Sinsuebphon,
Alena Rudkouskaya,
Margarida Barroso,
Xavier Intes,
Xavier Michalet Tags: FULL ARTICLE Source Type: research
Widefield multi ‐frequency fluorescence lifetime imaging using a two‐tap CMOS camera with lateral electric field charge modulators
This article is protected by copyright. All rights reserved. (Source: Journal of Biophotonics)
Source: Journal of Biophotonics - November 12, 2018 Category: Physics Authors: Hongtao Chen,
Ning Ma,
Keiichiro Kagawa,
Shoji Kawahito,
Michelle Digman,
Enrico Gratton Tags: FULL ARTICLE Source Type: research
Assessing Hemorrhagic Shock: Feasibility of Using an Ultracompact Photoacoustic Microscope
This article is protected by copyright. All rights reserved. (Source: Journal of Biophotonics)
Source: Journal of Biophotonics - November 12, 2018 Category: Physics Authors: Qian Chen,
Heng Guo,
Weizhi Qi,
Qi Gan,
Lei Yang,
Bowen Ke,
Xingxing Chen,
Tian Jin,
Lei Xi Tags: FULL ARTICLE Source Type: research
