Psychiatry and psychotherapy: the science of sitting with uncertainty
ConclusionAmbiguity and uncertainty in the setting of partial knowledge presents psychiatry with a challenge, yes; but it also enables psychiatry to be innovative in its approach, and to address the complexities of the human condition in a way that is unique and unparalleled within the field of medicine. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - April 23, 2024 Category: General Medicine Source Type: research
The impact of the COVID-19 pandemic on symptomatic breast cancer presentations in an Irish breast cancer unit: a retrospective cohort study
ConclusionSymptomatic breast cancers diagnosed since the onset of COVID-19 demonstrated an increase in new metastatic presentations and more aggressive histopathological characteristics when compared to a pre-pandemic control group. Rates of adjuvant radiotherapy and axillary surgery increased during the pandemic. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - April 19, 2024 Category: General Medicine Source Type: research
High keratin 15 expression reflects favorable prognosis in early cervical cancer patients
ConclusionHigh KRT15 expression reflects favorable tumor features and longer survival in early cervical cancer patients who receive tumor resection. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - April 19, 2024 Category: General Medicine Source Type: research
Letter to the Editor in regards to the article “Prognosticating acute traumatic spinal cord injury using Neurofilament (NF), Neuron Specific Enolase (NSE), Matrix Metalloproteinases (MMPs), and S-100B as biomarkers”
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - April 19, 2024 Category: General Medicine Source Type: research
Impacts of gait freeze on quality of life in Parkinson ’s disease, from the perspectives of patients and their carers
ConclusionsThis study shows that FoG is a significant detriment to the QoL of PwP, from the perspectives of patients and carers. This method of assessing FoG and QoL using online questionnaires has potential to enhance the reach and flexibility of this type of research. These findings will inform future studies on larger cohorts and highlight unmet clinical needs in PwP. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - April 19, 2024 Category: General Medicine Source Type: research
Does Parkinson ’s disease affect sleep quality?
ConclusionParkinson ’s disease patients had poorer sleep quality than the controls. Age and sex were not found to be expected as a factor for sleep quality in patients with Parkinson’s disease. Daytime dysfunction rates are high in patients with Parkinson’s disease. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - April 16, 2024 Category: General Medicine Source Type: research
Integration of an online application to optimise multi-disciplinary meetings: a retrospective analysis
Conclusion(s)Microsoft Office Forms proved to be a valuable and adaptable tool for MDMs, offering benefits such as streamlined information gathering, real-time collaboration, and scalability. The study highlights the potential of existing tools within Microsoft licenses for healthcare process optimisation, providing a cost-effective and customisable solution for MDM agendas. While recognising some limitations, the study concludes that leveraging Microsoft Office Forms can significantly improve system efficiency in a multi-disciplinary setting. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - April 15, 2024 Category: General Medicine Source Type: research
Comparison of sequential and mixture injections of opioids and hyperbaric bupivacaine for subarachnoid block for lower segment caesarean section: a randomised controlled study
ConclusionSequential injection of intrathecal opioids and hyperbaric bupivacaine resulted in greater early haemodynamic instability and slightly better postoperative analgesia without any difference in block height or patient satisfaction.Clinical trial registrationNCT04403724. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - April 11, 2024 Category: General Medicine Source Type: research
Dietary supplement beliefs and use patterns among Irish patients with early-stage breast cancer
ConclusionIn summary, supplement use is prevalent among BC patients. Development of guidelines in relation to safe use of dietary supplements after cancer diagnosis is crucial. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - April 6, 2024 Category: General Medicine Source Type: research
Valid consent in the acute hospital setting: perspectives of patients and members of the public
ConclusionsThe results highlight interesting similarities and differences in relation to consent between members of the public thinking about a possible treatment, surgery, or procedure and those patients who have actually been through the process in the past 12 months. Recommendations have been developed on the basis of these findings to co-design improvements in consent practices. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - April 5, 2024 Category: General Medicine Source Type: research
OpenAI ’s Sora in medicine: revolutionary advances in generative artificial intelligence for healthcare
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - April 4, 2024 Category: General Medicine Source Type: research
Optimising oncology drug expenditure in Ireland
AbstractA combination of improvements in patient survival, increasing treatment duration, and the development of more expensive agents has led to a doubling of per-capita spending on cancer medicines in Ireland (2008 –2018). Despite this, access to new drugs is poor in comparison to other EU countries. We examine methods to optimise oncology drug spending to facilitate access to newer anticancer agents. Key targets for spending optimisation (biosimilar use, clinical trials and expanded access programs, waste r eduction, avoidance of futile treatment, and altered drug scheduling) were identified through an exploratory ana...
Source: Irish Journal of Medical Science - April 3, 2024 Category: General Medicine Source Type: research
Paediatric Escherichia coli urinary tract infection: susceptibility trends and clinical management —a retrospective analysis of a 10-year period
ConclusionsThis study provides important regional AMR data. Co-amoxiclav susceptibility increased significantly over time, contrasting with previous studies. This was temporally associated with stewardship measures reducing co-amoxiclav prescribing. Decreasing utility of gentamicin supports recent CHI guideline updates reducing gentamicin use. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - April 3, 2024 Category: General Medicine Source Type: research
A prospective review of Cauda Equina Syndrome referrals received by an on-call orthopaedic department at a major trauma unit
ConclusionThere is a lack of understanding as to what exactly is being referred —resulting in a referral volume which is over ten times the expected number of CES cases being made to our unit. The lack of out-of-hours MRI access poses a significant concern for patient outcomes. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - April 2, 2024 Category: General Medicine Source Type: research
Sotagliflozin: an insight into the first dual SGLT inhibitor now approved for heart failure
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - March 25, 2024 Category: General Medicine Source Type: research
