Epidemiology, Etiology, and Pathophysiology of Pulmonary Embolism
Int J Angiol DOI: 10.1055/s-0044-1785487Over the last 20 years, there has been a progressive increase in the incidence of pulmonary embolism (PE) diagnosis in the United States, Europe, and Australia. Increased use of computed tomography pulmonary angiography has likely contributed in part to this rising incidence. However, it is pertinent to note that the burden of comorbidities associated with PE, such as malignancy, obesity, and advanced age, has also increased over the past 20 years. Time-trend analysis in North American, European, and Asian populations suggests that mortality rates associated with PE have been declini...
Source: International Journal of Angiology - April 12, 2024 Category: Cardiology Authors: Glazier, Catherine R. Baciewicz, Frank A. Tags: Review Article Source Type: research
A Brief Historical Perspective on Pulmonary Embolism
Int J Angiol DOI: 10.1055/s-0044-1782603Pulmonary embolism is a major cause of mortality worldwide. In this historical perspective, we aim to provide an overview of the rich medical history surrounding pulmonary embolism. We highlight Virchow's first steps toward understanding the pathophysiology in the 1800s. We see how those insights inspired early attempts at intervention such as surgical pulmonary embolectomy and caval ligation. Those early interventions were refined and ultimately led to the development of inferior vena cava filters, the earliest clinical applications of anticoagulation, and even apparently disparate ...
Source: International Journal of Angiology - April 5, 2024 Category: Cardiology Authors: Morgan, Clinton T. Saha, Sibu P. Tags: Review Article Source Type: research
Endothelial-Derived Microparticles Associate with Hospital Major Adverse Cardiovascular Events but not with Long-Term Adverse Events in Acute Myocardial Infarction
In conclusion, higher on-admission EDMP counts were independently associated with hospital MACE among AMI. However, on-admission and 30-day postdischarge EDMP and their changes did not impact long-term follow-up MACE. [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: International Journal of Angiology)
Source: International Journal of Angiology - April 2, 2024 Category: Cardiology Authors: Hartopo, Anggoro B. Mayasari, Dyah S. Puspitawati, Ira Putri, Astrid K. Setianto, Budi Y. Tags: Original Article Source Type: research
Enhanced External Counterpulsation Outcomes Study: Retrospective Analyses of Data Obtained from Patients at a Single Medical Center in United States
Int J Angiol DOI: 10.1055/s-0044-1782657The aim was to explore the effectiveness of enhanced external counterpulsation (EECP) therapy in patients with severe angina pectoris/ chronic heart failure symptoms, who were not suitable candidates for invasive treatment. This retrospective study employed a comprehensive methodology that includes individualized treatment, continuous monitoring, and thorough pre- and postprogram evaluations to assess the efficacy of EECP therapy. The standard protocol involved 35 one-hour treatments, with flexibility for extensions based on therapeutic progress. When pre- and posttreatment results w...
Source: International Journal of Angiology - March 30, 2024 Category: Cardiology Authors: Akula, Ashok Grafft, Heidi R. Tak, Nadia Haberman, Douglas A. Tak, Tahir Tags: Original Article Source Type: research
Risks and Benefits of Device-Assisted Treatment of Pulmonary Embolism
Int J Angiol DOI: 10.1055/s-0044-1782535Pulmonary embolism (PE) is a common disease associated with significant morbidity and mortality. Despite the familiarity with this disease, the best treatment remains undefined. Traditionally, treatment of PE has involved a choice of anticoagulation, thrombolysis, or surgery. However, the debate over pharmacologic versus mechanical treatment of acute PE reared up again with the advent of user-friendly mechanical and aspiration thrombectomy technologies. This is especially true for submassive PE, which is an area for potential growth both for understanding the pathophysiology of the d...
Source: International Journal of Angiology - March 26, 2024 Category: Cardiology Authors: Kim, Sofia Kim, Michael Kodra, Arber Tags: Review Article Source Type: research
Thrombus-Demarcated Stenting with Dual-Contrast Imaging: A Novel Approach for Late-ST-Segment Elevation Myocardial Infarction with Unsuccessful Predilatation
Int J Angiol DOI: 10.1055/s-0044-1782621The success of revascularization in the total occluded coronary lesion with dense thrombus burden is important for the short- and long-term prognosis of patients with acute ST-segment elevation myocardial infarction (STEMI). In these lesions, stenting without dispersing the thrombus can increase the success of revascularization without fatal complications. The aim of this case is to demonstrate the newly developed thrombus-demarcated stenting with dual-contrast imaging approach after unsuccessful predilatation in a late-inferior STEMI. In centers where optical coherence tomography is...
Source: International Journal of Angiology - March 22, 2024 Category: Cardiology Authors: Oguz, Mustafa Akbulut, Tayyar Saylik, Faysal Cinar, Tufan Tags: Case Report Source Type: research
Menstruation-Related Angina —The Wee Hours
Int J Angiol DOI: 10.1055/s-0044-1782602Literature reveals two kinds of menstruation-related anginas—cardiac syndrome X (CSX) and catamenial angina. CSX generally occurs in perimenopausal or postmenopausal women; catamenial angina affects females from puberty to menopause with existing/preexisting or predisposed to coronary artery disease. CSX involves recurring anginal-type retrosternal chest pains during exercise or rest with no significant findings on angiogram. Catamenial angina is menstruation-associated recurrent nonexertional left-sided chest pain alongside diaphoresis, hot flushes, and persistent lethargy. Pathop...
Source: International Journal of Angiology - March 15, 2024 Category: Cardiology Authors: Goyette, Sandy Mishra, Tulika Raza, Farah Naqvi, Zahra Khan, Sarah Khan, Abrar Igman, Pamphil Bhat, Malpe Surekha Tags: Review Article Source Type: research
Pulmonary Embolism in Donor Lungs —Incidence and Management
Int J Angiol DOI: 10.1055/s-0044-1782536In efforts to decrease the mortality on the waiting list for lung transplantation, alternatives to increase the donor pool have been explored. Caution must be used when accepting donor lungs with pulmonary embolism (PE), as prior evidence has shown mixed results after transplantation of donor lungs with PE. However, the mere diagnosis of PE on imaging should not be the sole reason for the exclusion of these donors for transplant, and they should be reviewed as any other donor. A comprehensive evaluation should be performed for every donor, with a special focus on abnormalities of gas...
Source: International Journal of Angiology - March 15, 2024 Category: Cardiology Authors: Carvalho, Juliano Lentz Keshavamurthy, Suresh Tags: Review Article Source Type: research
Anticoagulation in the Management of Acute Pulmonary Embolism —A Review
Int J Angiol DOI: 10.1055/s-0044-1782537Venous thromboembolism (VTE) is a very frequent cardiovascular entity that encompasses deep vein thrombosis and pulmonary embolism (PE). This last entity represents a major cause of cardiovascular morbidity and mortality. The incidence of PE and the rate of PE-related morbidity significantly increase with age, race, and underlying medical conditions, such as malignancy. Given the recent advances in diagnostic strategies and algorithms, patients can be risk assessed and treated promptly to avoid disease progression. Anticoagulation is the mainstay of treatment for acute PE that is not...
Source: International Journal of Angiology - March 12, 2024 Category: Cardiology Authors: del Toro Mijares, Raul Rojas Murguia, Adrian Porres-Aguilar, Mateo Mukherjee, Debabrata Tags: Review Article Source Type: research
miR-2467-3p/ABLIM1 Axis Mediates the Formation and Progression of Deep Vein Thrombosis by Regulating Inflammation and Oxidative Stress
Int J Angiol DOI: 10.1055/s-0044-1779663Deep vein thrombosis (DVT) is a common postoperative complication of orthopaedic surgery with a complex pathogenesis mechanism. The effect of the miR-2467-3p/acting-binding LIM protein 1 (ABLIM1) axis on thrombus formation and human vascular endothelial cells (HUVECs) progression was evaluated aiming to identify a novel potential biomarker of DVT. DVT rat models were established by inferior vena cava stenosis. The expression of the miR-2467-3p/ABLIM1 axis was analyzed by PCR. HUVECs were induced with oxidative low-density lipoprotein (ox-LDL). Cell growth and motility were assessed b...
Source: International Journal of Angiology - February 21, 2024 Category: Cardiology Authors: Qiu, Yu Yang, Meiying Che, Xinting Yu, Xinming Zhi, Kangkang Tags: Original Article Source Type: research
Pericardial Decompression Syndrome: A Comprehensive Review of a Controversial Entity
Int J Angiol DOI: 10.1055/s-0044-1780536Pericardial decompression syndrome is an ambiguous clinical entity which has generated controversy regarding its existence. Following pericardial decompression, patients experienced clinical deterioration ranging in complications from pulmonary edema to death that could not be attributed to any other distinct clinical pathology. Multiple theories have suggested the pathophysiology behind pericardial decompression syndrome is related to preload-afterload mismatch following pericardial decompression, coronary microvascular ischemia, and stress from high adrenergic state. Our review aim...
Source: International Journal of Angiology - February 16, 2024 Category: Cardiology Authors: Sarode, Karan Patel, Amar Arrington, Kedzie Makhija, Rakhee Mukherjee, Debabrata Tags: Review Article Source Type: research
Diagnostic Strategies in Pulmonary Embolism
Int J Angiol DOI: 10.1055/s-0044-1779661Key to the diagnosis of pulmonary embolism (PE) is a careful bedside evaluation. After this, there are three further diagnostic steps. In all patients, estimation of the clinical probability of PE is performed. The other two steps are measurement of D-dimer when indicated and chest imaging when indicated. The clinical probability of PE is estimated at low, moderate, or high. The prevalence of PE is less than 15% among patients with low clinical probability, 15 to 40% with moderate clinical probability, and >40% in patients with high clinical probability. Clinical gestalt has been ...
Source: International Journal of Angiology - February 12, 2024 Category: Cardiology Authors: Glazier, Margaret Mary Glazier, James J. Tags: Review Article Source Type: research
Are Hospital Admissions (Costs) and Mortality Rate Impacted by Guideline-driven Treatment of Heart Failure?: A Comparison between Participants in the “CorBene” CMP and Standard-care Patients on the Basis of Propensity Score Matching
Int J Angiol DOI: 10.1055/s-0044-1779660Heart failure (HF) is one of the most common diagnoses on admission to hospital in Germany, and one which incurs high costs. Integrated care in case management programs (CMPs) aims to improve treatment quality in the sense of guideline-driven treatment, while reducing hospital admissions, hospital costs, and mortality. A total of 1,844 patient data records from 11 German statutory health insurance companies enrolled in the CMP (intervention group [IG]) were compared with 1,844 standard-care patients (control group) using propensity score matching. The two groups were assessed over th...
Source: International Journal of Angiology - February 9, 2024 Category: Cardiology Authors: Ehling, Josef Nobl é, Hans Jürgen Gysan, Detlef M öller, Mareike Goss, Franz Haerer, Winfried Gl ück, Simon Bansmann, Paul Martin Tags: Original Article Source Type: research
Successful Retrieval of Retained Rotablator Burr in the Mid Left Anterior Descending Coronary Artery using a Retrograde Approach: A Case Report
We present a rare complication of Rotablator (Boston Scientific) atherectomy during percutaneous coronary intervention in a 67-year-old patient with a history of coronary artery disease and prior coronary artery bypass graft (CABG) surgery. The fracture of the Rotablator drive shaft and retention of the Rotablator burr in the mid left anterior descending coronary artery posed significant challenges in patient management. This case demonstrates the successful extraction of the retained Rotablator burr using retrograde total occlusion recanalization and highlights the importance of understanding the potential complications a...
Source: International Journal of Angiology - February 8, 2024 Category: Cardiology Authors: Inala, Yoshitha Robken, Jon Shammas, Nicolas W. Tags: Case Report Source Type: research
The Challenge of Managing a Primary Aortic Mural Thrombus: Outcomes and Technical Considerations
Conclusion: Anticoagulation alone as initial therapy could completely resolve PAMT but is associated with high embolization recurrence. Thoracic endovascular aortic repair is feasible and could prevent additional embolization. However, the criteria for its use as a first-line therapy still need to be defined. Our study highlights the importance of closely monitoring these patients. [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: International Journal of Angiology)
Source: International Journal of Angiology - February 6, 2024 Category: Cardiology Authors: Mendes, Daniel Veiga, Carlos Machado, Rui S á-Pinto, Pedro Almeida, Rui Tags: Original Article Source Type: research
