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Micronodular thymoma with lymphoid stroma: As benign as it sounds
We report a case received as a core biopsy from the "right lung mass" of a 31-year-old female. CT scan showed an 8.1 cm large well-defined mass lesion in the right middle lobe, causing indentation and mild compression of the right atrium. Microscopically, the biopsy showed a thymic neoplasm comprised of multiple discrete and coalescing nodules of bland epithelioid tumor cells separated by an epithelial cell-free lymphocyte-rich stroma. On immunohistochemistry, cytokeratin highlighted the thymic epithelial cells. The lymphoid cells showed a naive T-cell phenotype (TdT+ CD 3+). It is worthwhile recognizing this rare variant ...
Source: Indian Journal of Pathology and Microbiology - April 8, 2024 Category: Pathology Authors: Kanica Chaudhary Roshani Gala Jay Mehta Source Type: research

Micronodular thymoma with lymphoid stroma: As benign as it sounds
We report a case received as a core biopsy from the "right lung mass" of a 31-year-old female. CT scan showed an 8.1 cm large well-defined mass lesion in the right middle lobe, causing indentation and mild compression of the right atrium. Microscopically, the biopsy showed a thymic neoplasm comprised of multiple discrete and coalescing nodules of bland epithelioid tumor cells separated by an epithelial cell-free lymphocyte-rich stroma. On immunohistochemistry, cytokeratin highlighted the thymic epithelial cells. The lymphoid cells showed a naive T-cell phenotype (TdT+ CD 3+). It is worthwhile recognizing this rare variant ...
Source: Indian Journal of Pathology and Microbiology - April 8, 2024 Category: Pathology Authors: Kanica Chaudhary Roshani Gala Jay Mehta Source Type: research

Micronodular thymoma with lymphoid stroma: As benign as it sounds
We report a case received as a core biopsy from the "right lung mass" of a 31-year-old female. CT scan showed an 8.1 cm large well-defined mass lesion in the right middle lobe, causing indentation and mild compression of the right atrium. Microscopically, the biopsy showed a thymic neoplasm comprised of multiple discrete and coalescing nodules of bland epithelioid tumor cells separated by an epithelial cell-free lymphocyte-rich stroma. On immunohistochemistry, cytokeratin highlighted the thymic epithelial cells. The lymphoid cells showed a naive T-cell phenotype (TdT+ CD 3+). It is worthwhile recognizing this rare variant ...
Source: Indian Journal of Pathology and Microbiology - April 8, 2024 Category: Pathology Authors: Kanica Chaudhary Roshani Gala Jay Mehta Source Type: research

Micronodular thymoma with lymphoid stroma: As benign as it sounds
We report a case received as a core biopsy from the "right lung mass" of a 31-year-old female. CT scan showed an 8.1 cm large well-defined mass lesion in the right middle lobe, causing indentation and mild compression of the right atrium. Microscopically, the biopsy showed a thymic neoplasm comprised of multiple discrete and coalescing nodules of bland epithelioid tumor cells separated by an epithelial cell-free lymphocyte-rich stroma. On immunohistochemistry, cytokeratin highlighted the thymic epithelial cells. The lymphoid cells showed a naive T-cell phenotype (TdT+ CD 3+). It is worthwhile recognizing this rare variant ...
Source: Indian Journal of Pathology and Microbiology - April 8, 2024 Category: Pathology Authors: Kanica Chaudhary Roshani Gala Jay Mehta Source Type: research

Micronodular thymoma with lymphoid stroma: As benign as it sounds
We report a case received as a core biopsy from the "right lung mass" of a 31-year-old female. CT scan showed an 8.1 cm large well-defined mass lesion in the right middle lobe, causing indentation and mild compression of the right atrium. Microscopically, the biopsy showed a thymic neoplasm comprised of multiple discrete and coalescing nodules of bland epithelioid tumor cells separated by an epithelial cell-free lymphocyte-rich stroma. On immunohistochemistry, cytokeratin highlighted the thymic epithelial cells. The lymphoid cells showed a naive T-cell phenotype (TdT+ CD 3+). It is worthwhile recognizing this rare variant ...
Source: Indian Journal of Pathology and Microbiology - April 8, 2024 Category: Pathology Authors: Kanica Chaudhary Roshani Gala Jay Mehta Source Type: research

Micronodular thymoma with lymphoid stroma: As benign as it sounds
We report a case received as a core biopsy from the "right lung mass" of a 31-year-old female. CT scan showed an 8.1 cm large well-defined mass lesion in the right middle lobe, causing indentation and mild compression of the right atrium. Microscopically, the biopsy showed a thymic neoplasm comprised of multiple discrete and coalescing nodules of bland epithelioid tumor cells separated by an epithelial cell-free lymphocyte-rich stroma. On immunohistochemistry, cytokeratin highlighted the thymic epithelial cells. The lymphoid cells showed a naive T-cell phenotype (TdT+ CD 3+). It is worthwhile recognizing this rare variant ...
Source: Indian Journal of Pathology and Microbiology - April 8, 2024 Category: Pathology Authors: Kanica Chaudhary Roshani Gala Jay Mehta Source Type: research

Micronodular thymoma with lymphoid stroma: As benign as it sounds
We report a case received as a core biopsy from the "right lung mass" of a 31-year-old female. CT scan showed an 8.1 cm large well-defined mass lesion in the right middle lobe, causing indentation and mild compression of the right atrium. Microscopically, the biopsy showed a thymic neoplasm comprised of multiple discrete and coalescing nodules of bland epithelioid tumor cells separated by an epithelial cell-free lymphocyte-rich stroma. On immunohistochemistry, cytokeratin highlighted the thymic epithelial cells. The lymphoid cells showed a naive T-cell phenotype (TdT+ CD 3+). It is worthwhile recognizing this rare variant ...
Source: Indian Journal of Pathology and Microbiology - April 8, 2024 Category: Pathology Authors: Kanica Chaudhary Roshani Gala Jay Mehta Source Type: research

Micronodular thymoma with lymphoid stroma: As benign as it sounds
We report a case received as a core biopsy from the "right lung mass" of a 31-year-old female. CT scan showed an 8.1 cm large well-defined mass lesion in the right middle lobe, causing indentation and mild compression of the right atrium. Microscopically, the biopsy showed a thymic neoplasm comprised of multiple discrete and coalescing nodules of bland epithelioid tumor cells separated by an epithelial cell-free lymphocyte-rich stroma. On immunohistochemistry, cytokeratin highlighted the thymic epithelial cells. The lymphoid cells showed a naive T-cell phenotype (TdT+ CD 3+). It is worthwhile recognizing this rare variant ...
Source: Indian Journal of Pathology and Microbiology - April 8, 2024 Category: Pathology Authors: Kanica Chaudhary Roshani Gala Jay Mehta Source Type: research

Micronodular thymoma with lymphoid stroma: As benign as it sounds
We report a case received as a core biopsy from the "right lung mass" of a 31-year-old female. CT scan showed an 8.1 cm large well-defined mass lesion in the right middle lobe, causing indentation and mild compression of the right atrium. Microscopically, the biopsy showed a thymic neoplasm comprised of multiple discrete and coalescing nodules of bland epithelioid tumor cells separated by an epithelial cell-free lymphocyte-rich stroma. On immunohistochemistry, cytokeratin highlighted the thymic epithelial cells. The lymphoid cells showed a naive T-cell phenotype (TdT+ CD 3+). It is worthwhile recognizing this rare variant ...
Source: Indian Journal of Pathology and Microbiology - April 8, 2024 Category: Pathology Authors: Kanica Chaudhary Roshani Gala Jay Mehta Source Type: research

Poorly differentiated thyroid cancer: Clinical, pathological, mutational, and outcome analysis
CONCLUSION: PDTC presents with worrisome features like large size, ETE, and rapid growth. Aggressive surgical resection with extended/radical thyroidectomy may result in better loco-regional control and improved survival. RAS was the frequent mutation detected. It is worthwhile to identify prognostic factors that can predict the course of PDTC.PMID:38563686 | DOI:10.4103/ijpm.ijpm_885_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - April 2, 2024 Category: Pathology Authors: Amit Agarwal Nelson George Niraj Kumari Narendra Krishnani Prabhaker Mishra Sushil Gupta Source Type: research

A rare case of primary myelofibrosis with novel cytogenetic abnormality - deletion 4q25
Indian J Pathol Microbiol. 2024 Mar 25. doi: 10.4103/ijpm.ijpm_365_23. Online ahead of print.NO ABSTRACTPMID:38563691 | DOI:10.4103/ijpm.ijpm_365_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - April 2, 2024 Category: Pathology Authors: Debranjani Chattopadhyay Subhajit Hajra Harish Chandra Uttam K Nath Source Type: research

Cleidocranial dysplasia associated with dentigerous cyst-review of literature and case report of two siblings
Indian J Pathol Microbiol. 2024 Mar 25. doi: 10.4103/ijpm.ijpm_532_23. Online ahead of print.ABSTRACTCleidocranial dysplasia (CCD) is a developmental anomaly of the skeleton and teeth which may be inherited, be transmitted as dominant characteristics in either male or female or even appear spontaneously. A case was reported in the department of oral medicine and radiology of two sisters age 17 and 19 years old with a chief complaint of milk teeth not falling since childhood. They presented specific physical and oral findings in common which suggested the idea of an undiagnosed syndrome. The sisters showed CCD characteristi...
Source: Indian Journal of Pathology and Microbiology - April 2, 2024 Category: Pathology Authors: Nandini Bhardwaj Abhiney Puri Vijay Wadhwan Monika Gupta Source Type: research

Plausible mechanisms in malignisation of non-habit related chronic nonhealing traumatic ulcers of oral cavity
Indian J Pathol Microbiol. 2024 Mar 25. doi: 10.4103/ijpm.ijpm_800_23. Online ahead of print.ABSTRACTChronic nonhealing ulcers of the oral mucosa and lateral tongue, in particular, can transform into invasive oral squamous cell carcinoma (OSCC). Sometimes these ulcers do not heal even after the removal of the etiological agent that actually initiated these lesions, something similar to what happens in "neoplasia." Numerous factors have been postulated in the literature; however, the exact mechanism remains unclear. We hereby would suggest few plausible factors that could be considered for future studies to shed light on so...
Source: Indian Journal of Pathology and Microbiology - April 2, 2024 Category: Pathology Authors: Deepak Pandiar Reshma Poothakulath Krishnan Source Type: research

Rare complications of heart transplant: Autopsy findings
CONCLUSION: Hence, autopsy remains the key procedure that can help establish the cause of death after cardiac transplant. It is also imperative for clinicians to have awareness and high index of suspicion for early detection of the ongoing complications and intervene either surgically or medically to prevent catastrophic events.PMID:38563698 | DOI:10.4103/ijpm.ijpm_690_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - April 2, 2024 Category: Pathology Authors: Devika Gupta Lavan Singh Sameer Kumar Kanwaljeet Singh Satish Mendonca Tathagat Chatterjee Source Type: research

Role of direct antiglobulin test in anemia under evaluation: Its prevalence, laboratory workup, and significance in further patient management-a study from eastern India
CONCLUSION: DAT played a significant role in the diagnosis as well as evaluation of AIHA.PMID:38563700 | DOI:10.4103/ijpm.ijpm_724_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - April 2, 2024 Category: Pathology Authors: Sumita Pandey Chikam Maity Sambit K Samanta Arunansu Talukdar Arijit Das Sandip Paul Prasun Bhattacharya Pushpak Das Source Type: research