Serous cystic neoplasm of pancreas with surgical obstructive jaundice and double duct sign: Cystadenoma or cystadenocarcinoma?
(Source: Indian Journal of Gastroenterology)
Source: Indian Journal of Gastroenterology - April 18, 2024 Category: Gastroenterology Source Type: research

Analysis of donor morbidity in 177 donor hepatectomies for living donor liver transplant: Experience from a high-volume centre in western India
ConclusionDonor safety (outcome) is determined by meticulous donor surgery and good-quality remnant.Graphical abstract (Source: Indian Journal of Gastroenterology)
Source: Indian Journal of Gastroenterology - April 17, 2024 Category: Gastroenterology Source Type: research

Prediction of mortality from hepatitis A virus-related acute liver failure in children —Do we have the perfect prognostic model?
(Source: Indian Journal of Gastroenterology)
Source: Indian Journal of Gastroenterology - April 17, 2024 Category: Gastroenterology Source Type: research

Infected pancreatic necrosis —Current trends in management
AbstractAcute necrotizing pancreatitis is a common gastrointestinal disease requiring hospitalization and multiple interventions resulting in higher morbidity and mortality. Development of infection in such necrotic tissue is one of the sentinel events in natural history of necrotizing pancreatitis. Infected necrosis develops in around 1/3rd of patients with necrotizing pancreatitis resulting in higher mortality. So, timely diagnosis of infected necrosis using clinical, laboratory and radiological parameters is of utmost importance. Though initial conservative management with antibiotics and organ support system is effecti...
Source: Indian Journal of Gastroenterology - April 16, 2024 Category: Gastroenterology Source Type: research

Gastric pneumatosis and aeroportia in gastroparesis with recurring functional pyloric stenosis
(Source: Indian Journal of Gastroenterology)
Source: Indian Journal of Gastroenterology - April 16, 2024 Category: Gastroenterology Source Type: research

Longitudinal changes in bone mineral density may be associated with long-term survival in patients with cirrhosis: A proof of concept of study
ConclusionAmong body composition parameters, changes in bone mineral density correlate best with survival and have prognostic relevance similar to that of ascites and MELD score.Graphical Abstract (Source: Indian Journal of Gastroenterology)
Source: Indian Journal of Gastroenterology - April 15, 2024 Category: Gastroenterology Source Type: research

Hepatitis C virus core antigen: A diagnostic and treatment  monitoring marker of hepatitis C virus in Indian population
ConclusionsHCV core Ag assay is a cost-effective, practically feasible substitute of HCV RTPCR viral load assay for diagnosis as well as long duration treatment monitoring of hepatitis C infection in resource-limited settings.Graphical Abstract (Source: Indian Journal of Gastroenterology)
Source: Indian Journal of Gastroenterology - April 15, 2024 Category: Gastroenterology Source Type: research

Utility of proximal mean nocturnal basal impedance in gastroesophageal reflux disease —A preliminary experience
(Source: Indian Journal of Gastroenterology)
Source: Indian Journal of Gastroenterology - April 15, 2024 Category: Gastroenterology Source Type: research

Acute kidney injury in acute liver failure: A narrative review
AbstractAcute kidney injury (AKI) is a frequent complication of acute liver failure (ALF) and it worsens the already worse prognoses of ALF. ALF is an uncommon disease, with varying etiologies and varying definitions in different parts of the world. There is limited literature on the impact of AKI on the outcome of ALF with or without transplantation. The multifaceted etiology of AKI in ALF encompasses factors such as hemodynamic instability, systemic inflammation, sepsis and direct nephrotoxicity. Indications of renal replacement therapy (RRT) for AKI in ALF patients extend beyond the conventional criteria for dialysis an...
Source: Indian Journal of Gastroenterology - April 5, 2024 Category: Gastroenterology Source Type: research

Critical care management of acute liver failure
AbstractThe management of acute liver failure (ALF) in modern hepatology intensive care units  (ICU) has improved patient outcomes. Critical care management of hepatic encephalopathy, cerebral edema, fluid and electrolytes; prevention of infections and organ support are central to improved outcomes of ALF. In particular, the pathogenesis of encephalopathy is multifactorial, with ammonia, el evated intra-cranial pressure and systemic inflammation playing a central role. Although ALF remains associated with high mortality, the availability of supportive care, including organ failure support such as plasma exchange, timely m...
Source: Indian Journal of Gastroenterology - April 5, 2024 Category: Gastroenterology Source Type: research

Transforming lives: A triumph of public-private partnership in successful liver transplants
(Source: Indian Journal of Gastroenterology)
Source: Indian Journal of Gastroenterology - April 5, 2024 Category: Gastroenterology Source Type: research

Acute kidney injury in acute liver failure: A narrative review
AbstractAcute kidney injury (AKI) is a frequent complication of acute liver failure (ALF) and it worsens the already worse prognoses of ALF. ALF is an uncommon disease, with varying etiologies and varying definitions in different parts of the world. There is limited literature on the impact of AKI on the outcome of ALF with or without transplantation. The multifaceted etiology of AKI in ALF encompasses factors such as hemodynamic instability, systemic inflammation, sepsis and direct nephrotoxicity. Indications of renal replacement therapy (RRT) for AKI in ALF patients extend beyond the conventional criteria for dialysis an...
Source: Indian Journal of Gastroenterology - April 5, 2024 Category: Gastroenterology Source Type: research

Critical care management of acute liver failure
AbstractThe management of acute liver failure (ALF) in modern hepatology intensive care units  (ICU) has improved patient outcomes. Critical care management of hepatic encephalopathy, cerebral edema, fluid and electrolytes; prevention of infections and organ support are central to improved outcomes of ALF. In particular, the pathogenesis of encephalopathy is multifactorial, with ammonia, el evated intra-cranial pressure and systemic inflammation playing a central role. Although ALF remains associated with high mortality, the availability of supportive care, including organ failure support such as plasma exchange, timely m...
Source: Indian Journal of Gastroenterology - April 5, 2024 Category: Gastroenterology Source Type: research

Transforming lives: A triumph of public-private partnership in successful liver transplants
(Source: Indian Journal of Gastroenterology)
Source: Indian Journal of Gastroenterology - April 5, 2024 Category: Gastroenterology Source Type: research

Prognostic markers in hepatitis A –related pediatric acute liver failure and validation of the Peds-hepatitis A virus prognostic model
ConclusionINR, HE grade and JE interval were independent predictors of mortality. The study provides an external validation of Peds-HAV model as a prognostic score in HAV-PALF.Clinical trial registry numberNot applicable as this is a retrospective study.Graphical abstract (Source: Indian Journal of Gastroenterology)
Source: Indian Journal of Gastroenterology - April 3, 2024 Category: Gastroenterology Source Type: research