A critical review of the dextroamphetamine transdermal system for the treatment of ADHD in adults and pediatric patients
Expert Rev Neurother. 2024 May;24(5):457-464. doi: 10.1080/14737175.2024.2329306. Epub 2024 Mar 14.ABSTRACTINTRODUCTION: The dextroamphetamine transdermal system (d-ATS) is a stimulant patch recently approved by the United States (U.S.) Food and Drug Administration for the treatment of attention-deficit/hyperactivity disorder (ADHD).AREAS COVERED: The composition of the d-ATS, pharmacokinetics, and metabolism are presented along with data from dermal trials evaluating the tolerability of patch application at various skin sites. Efficacy and safety data from a laboratory classroom study in children and adolescents including...
Source: Expert Review of Neurotherapeutics - April 17, 2024 Category: Neurology Authors: Ann Childress Nicolas Vaughn Source Type: research

Pharmacological interventions to improve sleep in people with Alzheimer's disease: a meta-analysis of randomized controlled trials
CONCLUSION: Although melatonin was the most investigated intervention, the evidence for its efficacy is inconclusive. On the other hand, trazodone and orexin receptor antagonists showed promising results; however, more RCTs are needed for definite answers.PMID:38597219 | DOI:10.1080/14737175.2024.2341004 (Source: Expert Review of Neurotherapeutics)
Source: Expert Review of Neurotherapeutics - April 10, 2024 Category: Neurology Authors: Amy Bedward Jasmine Kaur Sadiyah Seedat Holly Donohue Chia Siang Kow Muhammad Kamran Rasheed Amaan Javed Syed Shahzad Hasan Source Type: research

Pharmacological interventions to improve sleep in people with Alzheimer's disease: a meta-analysis of randomized controlled trials
CONCLUSION: Although melatonin was the most investigated intervention, the evidence for its efficacy is inconclusive. On the other hand, trazodone and orexin receptor antagonists showed promising results; however, more RCTs are needed for definite answers.PMID:38597219 | DOI:10.1080/14737175.2024.2341004 (Source: Expert Review of Neurotherapeutics)
Source: Expert Review of Neurotherapeutics - April 10, 2024 Category: Neurology Authors: Amy Bedward Jasmine Kaur Sadiyah Seedat Holly Donohue Chia Siang Kow Muhammad Kamran Rasheed Amaan Javed Syed Shahzad Hasan Source Type: research