Expert Review of Clinical Immunology 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.The role of immune reconstitution in relapse after allogeneic hematopoietic stem cell transplantation
Expert Rev Clin Immunol. 2024 May;20(5):513-524. doi: 10.1080/1744666X.2023.2299728. Epub 2024 Jan 10.ABSTRACTINTRODUCTION: Leukemia relapse following stem cell transplantation remains a significant barrier to long-term remission. Timely and balanced immune recovery after transplantation is crucial for preventing leukemia relapse.AREAS COVERED: After an extensive literature search of PubMed and Web of Science through October 2023, we provide an overview of the dynamics of immune reconstitution and its role in controlling leukemia relapse. We also discuss strategies to promote immune reconstitution and reduce disease recurr...
Source: Expert Review of Clinical Immunology - April 10, 2024 Category: Allergy & Immunology Authors: Xu-Ying Pei Xiao-Jun Huang Source Type: research
Basophil activation test in the food allergy clinic: its current use and future applications
Expert Rev Clin Immunol. 2024 Apr 10:1-8. doi: 10.1080/1744666X.2024.2336568. Online ahead of print.ABSTRACTINTRODUCTION: The basophil activation test (BAT) has shown evidence of high sensitivity and high specificity to support the diagnosis of IgE-mediated allergy. It is a functional test that uses live cells analyzed by flow cytometry and thus needs to be performed within 24h of blood collection. BAT has shown to be reproducible and reliable when tested in a clinical diagnostic laboratory with standardized protocols and flow cytometry settings.AREAS COVERED: In this review, we summarize the evidence to support clinical u...
Source: Expert Review of Clinical Immunology - April 9, 2024 Category: Allergy & Immunology Authors: Marcel M Bergmann Alexandra F Santos Source Type: research
Basophil activation test in the food allergy clinic: its use current use and future applications
Expert Rev Clin Immunol. 2024 Apr 9. doi: 10.1080/1744666X.2024.2336568. Online ahead of print.ABSTRACTThe basophil activation test (BAT) has shown evidence of high sensitivity and high specificity to support the diagnosis of IgE-mediated allergy. It is a functional test that uses live cells analyzed by flow cytometry and thus needs to be performed within 24 h of blood collection. BAT has shown to be reproducible and reliable when tested in a clinical diagnostic laboratory with standardized protocols and flow cytometry settings. BAT has recently been included in Clinical Guidelines of Food Allergy Diagnosis and its impleme...
Source: Expert Review of Clinical Immunology - April 9, 2024 Category: Allergy & Immunology Authors: Marcel M Bergmann Alexandra F Santos Source Type: research
Neuro-ophthalmic challenges and multi-morbidity in vasculitis among the older adults
Expert Rev Clin Immunol. 2024 Apr 9:1-11. doi: 10.1080/1744666X.2024.2339893. Online ahead of print.ABSTRACTINTRODUCTION: Vasculitides are a heterogeneous group of disorders producing inflammation of blood vessels (e.g. arteries or veins). All major vasculitides potentially have ophthalmological symptoms and signs including visual loss. Co-morbidity, multimorbidity, polypharmacy, and geriatric syndromes all play important roles in patient outcomes for these rheumatic conditions in the elderly. This monograph reviews the NCBI PubMed database (Feb 2023) literature on the neuro-ophthalmic and geriatric considerations in vascu...
Source: Expert Review of Clinical Immunology - April 4, 2024 Category: Allergy & Immunology Authors: Caezaan Keshvani Noor Laylani Pamela Davila-Siliezar Jonathan Kopel Andrew G Lee Source Type: research
Neuro-ophthalmic challenges and multi-morbidity in vasculitis among the older adults
Expert Rev Clin Immunol. 2024 Apr 4. doi: 10.1080/1744666X.2024.2339893. Online ahead of print.ABSTRACTINTRODUCTION: Vasculitides are a heterogeneous group of disorders producing inflammation of blood vessels (e.g. arteries or veins). All major vasculitides potentially have ophthalmological symptoms and signs including visual loss. Co-morbidity, multimorbidity, polypharmacy and geriatric syndromes all play important roles in patient outcomes for these rheumatic conditions in the elderly. This monograph reviews the NCBI PubMed database (Feb 2023) literature on the neuro-ophthalmic and geriatric considerations in vasculitis....
Source: Expert Review of Clinical Immunology - April 4, 2024 Category: Allergy & Immunology Authors: Caezaan Keshvani Noor Laylani Pamela Davila-Siliezar Jonathan Kopel Andrew G Lee Source Type: research
In-vitro assays for immuno-oncology drug efficacy assessment and screening for personalized cancer therapy: scopes and challenges
Expert Rev Clin Immunol. 2024 Apr 3:1-18. doi: 10.1080/1744666X.2024.2336583. Online ahead of print.ABSTRACTINTRODUCTION: Immunotherapies have revolutionized cancer treatment, but often fail to produce desirable therapeutic outcomes in all patients. Due to the inter-patient heterogeneity and complexity of the tumor microenvironment, personalized treatment approaches are gaining demand. Researchers have long been using a range of in-vitro assays including 2D models, organoid co-cultures, and cancer-on-a-chip platforms for cancer drug screening. A comparative analysis of these assays with their suitability, high-throughput c...
Source: Expert Review of Clinical Immunology - March 28, 2024 Category: Allergy & Immunology Authors: Md Marufur Rahman Greg Wells Juha K Rantala Thomas Helleday Munitta Muthana Sarah J Danson Source Type: research
In-vitro assays for immuno-oncology drug efficacy assessment and screening for personalized cancer therapy: scopes and challenges
Expert Rev Clin Immunol. 2024 Mar 28. doi: 10.1080/1744666X.2024.2336583. Online ahead of print.ABSTRACTINTRODUCTION: Immunotherapies have revolutionized cancer treatment, but often fail to produce desirable therapeutic outcomes in all patients. Due to the inter-patient heterogeneity and complexity of the tumor microenvironment, personalized treatment approaches are gaining demand. Researchers have long been using a range of in-vitro assays including 2D models, organoid co-cultures, and cancer-on-a-chip platforms for cancer drug screening. A comparative analysis of these assays with their suitability, high-throughput capac...
Source: Expert Review of Clinical Immunology - March 28, 2024 Category: Allergy & Immunology Authors: Marufur Rahman Greg Wells Juha K Rantala Thomas Helleday Munitta Muthana Sarah J Danson Source Type: research
