Role of stiff atrium in elucidating diastolic dysfunction in Fontan circulation. Letter regarding the article ‘Exercise catheterization in adults post‐Fontan with normal and abnormal haemodynamic criteria: Insights into normal Fontan physiology’
(Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - April 20, 2024 Category: Cardiology Authors: Makoto Takei Tags: Letter to Editor Source Type: research
A roadmap for therapeutic discovery in pulmonary hypertension associated with left heart failure. A scientific statement of the Heart Failure Association (HFA) of the ESC and the ESC Working Group on Pulmonary Circulation & Right Ventricular Function
Pulmonary hypertension (PH) associated with left heart failure (LHF) (PH-LHF) is one of the most common causes of PH. It directly contributes to symptoms and reduced functional capacity and negatively affects right heart function, ultimately leading to a poor prognosis. There are no specific treatments for PH-LHF, despite the high number of drugs tested so far. This scientific document addresses the main knowledge gaps in PH-LHF with emphasis on pathophysiology and clinical trials. Key identified issues include better understanding of the role of pulmonary venous versus arteriolar remodelling, multidimensional phenotyping ...
Source: European Journal of Heart Failure - April 19, 2024 Category: Cardiology Authors: Pietro Ameri,
Valentina Mercurio,
Piero Pollesello,
Markus S. Anker,
Johannes Backs,
Antoni Bayes ‐Genis,
Barry A. Borlaug,
Daniel Burkhoff,
Sergio Caravita,
Stephen Y. Chan,
Frances de Man,
George Giannakoulas,
Aránzazu González,
Marco G Tags: Position Paper Source Type: research
Mitral regurgitation in heart failure with preserved ejection fraction: The interplay of valve, ventricle, and atrium
The interplay of MR and HFpEF: understanding increased pulmonary pressures and strategies for management. HFpEF, heart failure with preserved ejection fraction; MR, mitral valve regurgitation. AbstractMitral regurgitation (MR) is highly prevalent among patients with heart failure and preserved ejection fraction (HFpEF). Despite this combination being closely associated with unfavourable outcomes, it remains relatively understudied. This is partly due to the inherent heterogeneity of patients with HFpEF. To address this gap, dissecting HFpEF into mechanism-based phenotypes may offer a promising avenue for advancing our comp...
Source: European Journal of Heart Failure - April 18, 2024 Category: Cardiology Authors: Sebastiaan Dhont,
Gitte van den Acker,
Tim van Loon,
Frederik H. Verbrugge,
Jan Verwerft,
S ébastien Deferm,
Timothy W. Churchill,
Wilfried Mullens,
Joost Lumens,
Philippe B. Bertrand Tags: Review Article Source Type: research
Long ‐term efficacy and safety of tailored immunosuppressive therapy in immune‐mediated biopsy‐proven myocarditis: A propensity‐weighted study
ConclusionsProlonged tailored IS is effective and safe in BP immune-mediated myocarditis irrespective of histology and clinical presentation. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - April 17, 2024 Category: Cardiology Authors: Alida Linda Patrizia Caforio,
Andrea Silvio Giordani,
Anna Baritussio,
Davide Marcolongo,
Cristina Vicenzetto,
Giuseppe Tarantini,
Massimo Napodano,
Giuseppe Toscano,
Dario Gregori,
Gloria Brigiari,
Patrizia Bartolotta,
Elisa Carturan,
Monica Tags: Research Article Source Type: research
Time to clinical benefit with sotagliflozin in patients with type 2 diabetes and chronic kidney disease: Insights from the SCORED randomized trial
(Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - April 17, 2024 Category: Cardiology Authors: Rahul Aggarwal,
Deepak L. Bhatt,
Michael Szarek,
Lawrence A. Leiter,
Christopher P. Cannon,
Renato D. Lopes,
Michael J Davies,
Phillip Banks,
Bertram Pitt,
Ph. Gabriel Steg Tags: Research Letter Source Type: research
Reporting quality of heart failure randomized controlled trials 2000 –2020: Temporal trends in adherence to CONSORT criteria
ConclusionThe quality of reporting in HF RCTs, as measured by CONSORT adherence, has improved over time but remains suboptimal. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - April 17, 2024 Category: Cardiology Authors: Mohamed B. Jalloh,
Veronica A. Bot,
Cristiana Z. Borjaille,
Lehana Thabane,
Guowei Li,
Javed Butler,
Faiez Zannad,
Christopher B. Granger,
Harriette G.C. Van Spall Tags: Research Article Source Type: research
The changing landscape of heart failure treatment in transthyretin amyloid cardiomyopathy: Is the time ripe for clinical use of sodium –glucose cotransporter 2 inhibitors?
(Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - April 16, 2024 Category: Cardiology Authors: Aldostefano Porcari,
Marianna Fontana Tags: Invited Editorial Source Type: research
Serum metabolomics improves risk stratification for incident heart failure
ConclusionSerum metabolomics improves incident HF risk prediction over PCP-HF. Scores based on age, sex and metabolomics exhibit similar predictive power to clinically-based models, potentially offering a cost-effective, standardizable, and scalable single-domain alternative. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - April 16, 2024 Category: Cardiology Authors: Rafael R. Oexner,
Hyunchan Ahn,
Konstantinos Theofilatos,
Ravi A. Shah,
Robin Schmitt,
Philip Chowienczyk,
Anna Zoccarato,
Ajay M. Shah Tags: Research Article Source Type: research
Dietary sodium and fluid intake in heart failure. A clinical consensus statement of the Heart Failure Association of the ESC
Sodium and fluid restriction has traditionally been advocated in patients with heart failure (HF) due to their sodium and water avid state. However, most evidence regarding the altered sodium handling, fluid homeostasis and congestion-related signs and symptoms in patients with HF originates from untreated patient cohorts and physiological investigations. Recent data challenge the beneficial role of dietary sodium and fluid restriction in HF. Consequently, the European Society of Cardiology HF guidelines have gradually downgraded these recommendations over time, now advising for the limitation of salt intake to no more tha...
Source: European Journal of Heart Failure - April 13, 2024 Category: Cardiology Authors: Wilfried Mullens,
Kevin Damman,
Sebastiaan Dhont,
Debasish Banerjee,
Antoni Bayes ‐Genis,
Antonio Cannata,
Ovidiu Chioncel,
Maja Cikes,
Justin Ezekowitz,
Andreas J. Flammer,
Pieter Martens,
Alexandre Mebazaa,
Robert J. Mentz,
Òscar Miró, Tags: Position Paper Source Type: research
Cause ‐specific death in heart failure across the ejection fraction spectrum: A comprehensive assessment of over 100 000 patients in the Swedish Heart Failure Registry
ConclusionCardiovascular death was more common than non-CV death across all EF categories although the risk of non-CV death within 5 years was higher with increasing EF. IHD and cancer were the most common causes of CV and non-CV deaths, respectively, regardless of EF category. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - April 12, 2024 Category: Cardiology Authors: Camilla Settergren,
Lina Benson,
Angiza Shahim,
Ulf Dahlstr öm,
Tonje Thorvaldsen,
Gianluigi Savarese,
Lars H. Lund,
Bahira Shahim Tags: Research Article Source Type: research
Heart failure and respiratory tract infection: Cause and consequence of acute decompensation?
(Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - April 12, 2024 Category: Cardiology Authors: Bettina Heidecker,
Matteo Pagnesi,
Thomas F. L üscher Tags: Invited Editorial Source Type: research
Impact of guideline ‐directed medical therapy on systolic blood pressure and cardiovascular outcomes in patients with heart failure and low blood pressure: A systematic review and meta‐analysis
ConclusionsGuideline-directed medical therapy is associated with a negligible decrease in SBP, but can provide similar cardiovascular benefits in both low and non-low SBP HF patients, with no significant interaction with SBP as to hypotension. Therefore, GDMT should be initiated and maintained in HF patients with low BP. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - April 12, 2024 Category: Cardiology Authors: Jingwei Li,
Yunlong Chen,
Yi Wang,
Xiaoyan Liu,
Ping Li,
Yongming He,
Yang Hao,
Lan Huang,
Jun Jin,
Jiang Wang,
Craig Anderson Tags: Research Article Source Type: research
Baroreflex activation therapy in patients with heart failure and a reduced ejection fraction: Long ‐term outcomes
ConclusionThe BeAT-HF primary endpoint was neutral; however, BAT provided safe, effective, and sustainable improvements in HFrEF patient's functional status, 6MHWD and QOL. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - April 12, 2024 Category: Cardiology Authors: Michael R. Zile,
JoAnn Lindenfeld,
Fred A. Weaver,
Faiez Zannad,
Elizabeth Galle,
Tyson Rogers,
William T. Abraham Tags: Research Article Source Type: research
N ‐terminal pro‐B‐type natriuretic peptide post‐discharge monitoring in the management of patients with heart failure and preserved ejection fraction – a randomized trial: The NICE study
ConclusionsPost-discharge monitoring of NT-proBNP in HFpEF patients did not exhibit an association with reduced rates of HF hospitalization in this study. Nonetheless, it appears to enhance global clinical management by optimizing medical therapies and contributing to improved overall survival. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - April 12, 2024 Category: Cardiology Authors: Domingo A. Pascual ‐Figal,
Alvaro Hernández‐Vicente,
Francisco Pastor‐Pérez,
Manuel Martínez‐Sellés,
Eduard Solé‐González,
Jesús Alvarez‐García,
Pablo García‐Pavía,
Alfonso Varela‐Román,
Pedro Luis Sánchez,
Juan F. Del Tags: Research Article Source Type: research
Reply to ‘The pharmacist ally in heart failure: Useful when involved’
(Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - April 12, 2024 Category: Cardiology Authors: Craig J. Beavers,
Deepak L. Bhatt,
Gad Gotter Tags: Letter to the Editor Source Type: research
