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Dupilumab in patients with atopic dermatitis: assessing treatment response, clinical features and potential biomarkers in real-life
Conclusions. In this cohort, none of the evaluated biomarkers at baseline were associated with a better/earlier clinical response to dupilumab. Dupilumab treatment for 52 weeks resulted in a significant and sustained reduction in blood levels of total IgE and allergen-specific IgE to aeroallergens. The potential long-term clinical benefit of these effects, even after discontinuing dupilumab therapy in patients with AD, should be explored to a greater extent.PMID:38591168 | DOI:10.23822/EurAnnACI.1764-1489.341 (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - April 9, 2024 Category: Allergy & Immunology Authors: R Lim ão R Br ás E Pedro S L Silva A Lopes Source Type: research

Selective Immunoglobulin M Deficiency: an underestimated immunodeficiency
Eur Ann Allergy Clin Immunol. 2024 Apr 5. doi: 10.23822/EurAnnACI.1764-1489.340. Online ahead of print.NO ABSTRACTPMID:38578199 | DOI:10.23822/EurAnnACI.1764-1489.340 (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - April 5, 2024 Category: Allergy & Immunology Authors: I C Farinha A C Dias Pereira F S Regateiro A Todo-Bom E Faria Source Type: research

Eosinophil-associated diseases: the allergist's and clinical immunologist's perspective
Eur Ann Allergy Clin Immunol. 2024 Mar 28. doi: 10.23822/EurAnnACI.1764-1489.339. Online ahead of print.ABSTRACTEosinophil-associated diseases (EADs) refer to heterogeneous conditions in which eosinophils are believed to play critical pathological roles. They encompass common respiratory conditions, such as asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), less common primary eosinophilic disorders of gastrointestinal tract, and rare conditions including eosinophilic granulomatosis with polyangiitis (EGPA) and hypereosinophilic syndrome (HES). A literature search was carried out in January 2024 in the MEDLINE and ...
Source: European Annals of Allergy and Clinical Immunology - March 28, 2024 Category: Allergy & Immunology Authors: A M Marra C M Rossi M A Piga G Moroncini M B Bil ò Source Type: research