To die or not to die in response to stress, a decision regulated by MK2 protein levels
(Institute for Research in Biomedicine (IRB Barcelona)) Researchers at IRB Barcelona unveil a pathway that determines the fate of cells in response to stress conditions and identify an important mechanism that recovers cell balance. The results have been published in the journal PNAS. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 19, 2021 Category: Cancer & Oncology Source Type: news
Ficlatuzumab plus chemotherapy may benefit patients with relapsed/refractory AML
(American Association for Cancer Research) The investigational therapeutic ficlatuzumab in combination with chemotherapy showed signs of clinical efficacy in patients with relapsed/refractory acute myeloid leukemia. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 16, 2021 Category: Cancer & Oncology Source Type: news
Oncotarget: RAS reversion in colorectal cancer patients treated with bevacizumab
(Impact Journals LLC) This Oncotarget finding might have potential therapeutic implications, as anti-EGFR could be reconsidered in primarily RAS mutant patients reverted to a wild-type status after bevacizumab exposure. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 16, 2021 Category: Cancer & Oncology Source Type: news
Ludwig Cancer Research study reveals even transient chromosomal errors can initiate cancer
(Ludwig Institute for Cancer Research) A Ludwig Cancer Research study has found that inducing random chromosome instability (CIN) events in mice for as little as one week is enough to trigger harmful chromosomal patterns in cells that spur the formation of tumors. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 16, 2021 Category: Cancer & Oncology Source Type: news
Cellular push and pull, a key to the body's response to processes such as cancer
(Institute for Bioengineering of Catalonia (IBEC)) Researchers led by Pere Roca-Cusachs at the Institute for Bioengineering of Catalonia (IBEC) and Isaac Almendros at IDIBAPS discover how force dynamics affect cells, and living tissues. The results give an insight into the critical mechanical processes that occur in different diseases such as cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 16, 2021 Category: Cancer & Oncology Source Type: news
New Sinai Health research finds common denominator linking all cancers
(Lunenfeld-Tanenbaum Research Institute) All cancers fall into just two categories, according to new research from scientists at Sinai Health, in findings that could provide a new strategy for treating the most aggressive and untreatable forms of the disease.In new research out this month in Cancer Cell, scientists at the Lunenfeld-Tanenbaum Research Institute (LTRI) divide all cancers into two groups, based on the presence or absence of a protein called the Yes-associated protein, or YAP. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 16, 2021 Category: Cancer & Oncology Source Type: news
A noninvasive test to detect cancer cells and pinpoint their location
(Massachusetts Institute of Technology) MIT engineers have created a nanoparticle for cancer diagnosis that can reveal the presence of cancerous proteins through a urine test, and can also function as an imaging agent, pinpointing the tumor location. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 15, 2021 Category: Cancer & Oncology Source Type: news
Can turmeric reduce joint pain during breast cancer treatment?
(University of California - Davis Health) The UC Davis Comprehensive Cancer Center received a $50,000 grant from the Safeway Foundation. The funding will allow researcher Mili Arora to study whether the spice turmeric can provide pain relief for breast cancer patients on oral anti-estrogen drugs. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 15, 2021 Category: Cancer & Oncology Source Type: news
Moffitt Physician receives NCI Cancer Clinical Investigator Team Leadership Award
(H. Lee Moffitt Cancer Center& Research Institute) Zeynep Eroglu, MD, assistant member of the Cutaneous Oncology Department at Moffitt Cancer Center, received the 2021 Cancer Clinical Investigator Team Leadership Award from the National Cancer Institute. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 15, 2021 Category: Cancer & Oncology Source Type: news
Routine screening for BI-RADS lesions on automated whole-breast ultrasound
(American Roentgen Ray Society) According to ARRS' American Journal of Roentgenology, return to routine screening for BI-RADS 3 lesions on supplemental automated whole-breast ultrasound (ABUS) substantially reduces the recall rate, while being unlikely to result in adverse outcome. This prospective study supports a recommendation for routine annual follow-up for BI-RADS 3 lesions at supplemental ABUS. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 15, 2021 Category: Cancer & Oncology Source Type: news
Helping working cancer caregivers manage stress
(University of Colorado Anschutz Medical Campus) Bradley received a nearly $4 million grant from the National Cancer Institute to study ways to lessen the impacts of stress specifically on cancer caregivers who are also employed. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 15, 2021 Category: Cancer & Oncology Source Type: news
Screening often misses endometrial cancer in Black women
In this study using a simulated cohort, TVUS endometrial thickness screening missed over four times more cases of endometrial cancer among Black women versus White women owing to the greater prevalence of fibroids and non-endometrioid histology type that occurs among Black women. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 15, 2021 Category: Cancer & Oncology Source Type: news
Low-dose radiotherapy combined with immunotherapy eradicates metastatic cancer in mice
(University of Pittsburgh) More doesn't necessarily mean better - including in cancer treatment. University of Pittsburgh School of Medicine and University of Wisconsin-Madison scientists report today in Science Translational Medicine that combining targeted radiopharmaceutical therapy with immunotherapy significantly boosts eradication of metastatic cancer in mice, even when the radiation is given in doses too low to destroy the cancer outright. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 14, 2021 Category: Cancer & Oncology Source Type: news
Drug combination shows meaningful responses for malignant peritoneal mesothelioma patient
(University of Texas M. D. Anderson Cancer Center) A phase II study led by researchers from The University of Texas MD Anderson Cancer Center found that treatment with atezolizumab and bevacizumab was well-tolerated and resulted in a 40% objective response rate in patients with advanced malignant peritoneal mesothelioma, a rare cancer in the lining of the abdomen (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 14, 2021 Category: Cancer & Oncology Source Type: news
LETI's research will help apply magnetotactic bacteria in oncology
(Saint Petersburg Electrotechnical University LETI) Kamil Gareev, Associate Professor at ETU " LETI, " justified the prospects of using magnetotactic bacteria to treat malignant tumors. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 14, 2021 Category: Cancer & Oncology Source Type: news
