Standard therapy or additionally radioactive iodine (131I) therapy; which will stop the recurrence of glioblastoma multiforme (GBM)?
Endokrynol Pol. 2024 Apr 22. doi: 10.5603/ep.98240. Online ahead of print.ABSTRACTGlioblastoma multiforme (GBM) is the most aggressive malignant brain tumour. The average survival time for a patient diagnosed with GBM, using standard treatment methods, is several months. Authors of the article pose a direct question: Is it possible to treat GBM solely with radioactive iodine (¹³¹I) therapy without employing the sodium iodide symporter (NIS) gene? After all, NIS has been detected not only in the thyroid but also in various tumours. The main author of this article (A.C.), with the assistance of her colleagues (physicians ...
Source: Endokrynologia Polska - April 22, 2024 Category: Endocrinology Authors: Agata Czarnywojtek Pawe ł Gut Kamil Dyrka Jerzy Sowi ński Nadia Sawicka-Gutaj Katarzyna Katulska Piotr Stajgis Mateusz Wykr ętowicz Jakub Moskal Jeremi Ko ściński Krzysztof Pietro ńczyk Patryk Graczyk Maciej Robert Krawczy ński Ewa Florek Ewelina S Source Type: research
Glycaemic control among adults with type 2 diabetes mellitus in the Gulf Cooperation Council countries: an updated review
Endokrynol Pol. 2024 Apr 22. doi: 10.5603/ep.99519. Online ahead of print.ABSTRACTType 2 diabetes mellitus (T2DM) has become a major public health concern, causing significant disability and death worldwide. Fuelled by a modern sedentary lifestyle and poor dietary practices, T2DM affects at least 10.5% of the world's population. This paper seeks to review the progress made by the Gulf Cooperation Council (GCC) countries (Bahrain, Kuwait, Oman, Qatar, Saudi Arabia, and the United Arab Emirates) in addressing T2DM, focusing on glycaemic control proportions and comparing it with the 2015 review. The results indicate no signif...
Source: Endokrynologia Polska - April 22, 2024 Category: Endocrinology Authors: Ahmad Ali Alrasheedi Source Type: research
The role of genetic risk factors, diet, and gut microbiota in type 1 diabetes mellitus, pancreas and pancreatic islet transplantation
Endokrynol Pol. 2024 Apr 22. doi: 10.5603/ep.98903. Online ahead of print.ABSTRACTDespite advances in insulin delivery and glucose monitoring technology, prevention of the progression of secondary complications in patients with type 1 diabetes (T1DM) remains a challenge. Beta cell replacement therapy in the form of islet or pancreas transplantation can restore long-term normoglycaemia with sustained periods of insulin independence among T1DM patients. However, the same genetic, behavioural, or gut microbiota-related factors that promoted autoimmunity and primary islet destruction may also affect the function of transplante...
Source: Endokrynologia Polska - April 22, 2024 Category: Endocrinology Authors: Agnieszka Zawada Marzena Skrzypczak-Zieli ńska Sarah Gondek Piotr Witkowski Anna M Rychter Alicja E Ratajczak-Paw łowska Marek Karczewski Agnieszka Dobrowolska Iwona Krela-Ka źmierczak Source Type: research
Circulating levels of irisin and Meteorin-like protein in PCOS and its correlation with metabolic parameters
CONCLUSIONS: Although irisin seems to be a promising biomarker, inconsistent research limits its value in clinical use in the assessment or treatment of obesity. Metrnl level was not affected in the study population, but it might be connected to the severity of metabolic disturbances.PMID:38646985 | DOI:10.5603/ep.99111 (Source: Endokrynologia Polska)
Source: Endokrynologia Polska - April 22, 2024 Category: Endocrinology Authors: Katarzyna Paczkowska Joachim Sobczuk Katarzyna Zawadzka Diana J ędrzejuk Agnieszka Zembska Jacek Konieczny Dorota Kaszubkiewicz-Ward ęga Marek Bolanowski Jacek Daroszewski Source Type: research
Ultrasound and cytopathological characteristics of thyroid tumours of uncertain malignant potential - from diagnosis to treatment
CONCLUSIONS: The study indicates that lesions with uncertain malignant potential typically present features suggesting low to intermediate risk of malignancy based on EU-TIRADS-PL classification, with dominant cytopathologic Bethesda IV category. However, 20% of lesions were assessed tas EU-TIRADS-PL category 5. Low-risk tumours, including NIFTP, FT-UMP, and WDT-UMP, require careful observation and monitoring post surgical treatment due to their potential for recurrence and metastasis. The preoperatively prediction of borderline tumour may play an important role in proper treatment and follow-up.PMID:38646986 | DOI:10.5603...
Source: Endokrynologia Polska - April 22, 2024 Category: Endocrinology Authors: Agnieszka Żyłka Katarzyna Dobruch-Sobczak Hanna Piotrzkowska-Wr óblewska Maciej J ędrzejczyk Piotr G óralski Jacek Ga łczyński Elwira Baku ła-Zalewska Marek Dedecjus Source Type: research
Elevated serum irisin levels in boys with central precocious puberty independent of BMI
CONCLUSIONS: Serum irisin levels correlate with BMI and pubertal development. Given its limited sensitivity, irisin level can only be utilised as a supplementary rather than a standalone diagnostic indicator for CPP.PMID:38646987 | DOI:10.5603/ep.98509 (Source: Endokrynologia Polska)
Source: Endokrynologia Polska - April 22, 2024 Category: Endocrinology Authors: Dan Zeng Yanfei Chen Tao Xie Wei Qin Qi Meng Dan Lan Source Type: research
Serum testosterone levels and oxidative stress in type 1 diabetes, type 2 diabetes, and obesity
CONCLUSIONS: Increased oxidative stress in diabetes may be an important factor that decreases serum testosterone levels.PMID:38646988 | DOI:10.5603/ep.98190 (Source: Endokrynologia Polska)
Source: Endokrynologia Polska - April 22, 2024 Category: Endocrinology Authors: Hamit Yasar Ellidag Rahime Aslanko ç Mehmet K ök G üzin Aykal Özgür Aydın Özlem Özmen Remzi Can Çakır U ğur Doğan Source Type: research
Clinical predictive value of Control attenuation parameters in combination with miR-192-5p in patients with acute pancreatitis in nonalcoholic fatty liver disease
CONCLUSIONS: NAFLD exacerbated the progression of AP, and CAP combined with miR-192-5p could predict the severity of AP. Our study may provide more reference for AP disease progression and treatment.PMID:38646989 | DOI:10.5603/ep.98765 (Source: Endokrynologia Polska)
Source: Endokrynologia Polska - April 22, 2024 Category: Endocrinology Authors: Yang Hu Liang Zhu Ronglai Cao Source Type: research
Human papillomavirus and Epstein-Barr virus infection in benign thyroid lesions
CONCLUSION: The occurrence and development of benign thyroid lesions are closely related to EBV infection. HT combined with thyroid adenoma may be more susceptible to EBV infection than simple HT and thyroid adenoma, which provides a new idea for the diagnosis and treatment of benign thyroid lesions.PMID:38646990 | DOI:10.5603/ep.99339 (Source: Endokrynologia Polska)
Source: Endokrynologia Polska - April 22, 2024 Category: Endocrinology Authors: Yingying Lu Runyu Zhao Yi Zhang Shuixian Huang Xiaoping Chen Source Type: research
Establishment of pregnancy-specific lipid reference intervals in pregnant women in a single-centre and assessment of the predictive value of early lipids for gestational diabetes mellitus: a prospective cohort study
CONCLUSIONS: This study established pregnancy-specific lipid RI for pregnant women in a single centre in the Beijing area of China. Pregnant women with TG ≥ 2.375 mmol/L in the first trimester were at significantly increased risk for GDM.PMID:38646991 | DOI:10.5603/ep.98554 (Source: Endokrynologia Polska)
Source: Endokrynologia Polska - April 22, 2024 Category: Endocrinology Authors: Dan Zhao Ning Yuan Jianbin Sun Xin Zhao Xiaomei Zhang Source Type: research
Oncocytoma in adrenal gland
Endokrynol Pol. 2024 Apr 22. doi: 10.5603/ep.99035. Online ahead of print.ABSTRACTNot required for Clinical Vignettes.PMID:38646992 | DOI:10.5603/ep.99035 (Source: Endokrynologia Polska)
Source: Endokrynologia Polska - April 22, 2024 Category: Endocrinology Authors: Tomasz Sko łozdrzy Jan Wojciechowski Magdalena Lewandowska-Lula Miros ław Halczak Maciej Romanowski Source Type: research
Acoustic outcomes and voice-related quality of life in male-to-female transsexuals undergoing Wendler glottoplasty: a single-centre experience
CONCLUSIONS: WG constitutes an effective method of surgical voice feminisation in male-to-female transsexuals with concurrent improvement in their voice-related QoL. Furthermore, it remains a safe procedure without persistent complications and negative influence on the acoustic-aerodynamic measures of the voice.PMID:38497370 | DOI:10.5603/ep.98899 (Source: Endokrynologia Polska)
Source: Endokrynologia Polska - March 18, 2024 Category: Endocrinology Authors: Maciej Misio łek Marta Rogalska Maciej Zieli ński Anna Kasperczuk Anna Koniewska Source Type: research
Diabetic gastroparesis: a disease for which long-term therapeutic benefits are difficult to obtain
Endokrynol Pol. 2024 Mar 18. doi: 10.5603/ep.97086. Online ahead of print.ABSTRACTThe pathophysiology of diabetic gastroparesis (DGP), a common complication in diabetic patients, is not fully known. Its development has been linked to several causes, including hyperglycaemia, vagal nerve dysfunction, aberrant Cajal's interstitial cell network (ICC), lack of nerve nitric oxide synthase (nNOS) expression in the intermuscular plexus, and hormonal alterations in the gastrointestinal tract. Glucose management, diet control, gastric stimulants, anti-emetic medications, Helicobacter pylori eradication, stomach electrical stimulati...
Source: Endokrynologia Polska - March 18, 2024 Category: Endocrinology Authors: Jun Zhou Sha Li Ran Ying Chang Zhao Source Type: research
Modifiable risk factors for thyroid cancer: lifestyle and residence environment
This article endeavours to elucidate the correlation between lifestyle, residential environment, and the increased prevalence of thyroid cancer in recent years. It specifies the frequency of the lifestyle and outlines the scope of the residential environment. It also endeavours to summarise the main mechanistic pathways of various modifiable risk factors that cause thyroid cancer. Factors that prevent thyroid cancer include smoking and alcohol consumption, quality and regular sleep, consumption of cruciferous vegetables and dairy products, and consistent long-term exercise. Conversely, individuals with specific genetic mut...
Source: Endokrynologia Polska - March 18, 2024 Category: Endocrinology Authors: Yi Shen Xian Wang Lu Wang Dandan Xiong Cailian Wu Liting Cen Lianguang Xie Xiangzhi Li Source Type: research
Multisystem inflammatory syndrome in children with Kawasaki disease-like manifestations in MMA
Endokrynol Pol. 2024 Mar 18. doi: 10.5603/ep.98192. Online ahead of print.ABSTRACTNot required for Clinical Vignette.PMID:38497373 | DOI:10.5603/ep.98192 (Source: Endokrynologia Polska)
Source: Endokrynologia Polska - March 18, 2024 Category: Endocrinology Authors: Miao Huang Xiyan Lu Yongmei Zeng Wujin Wang Jiyong Zhang Liting Wang Guoqing Dong Source Type: research
