Enhancement of the Tumor Suppression Effect of High-dose Radiation by Low-dose Pre-radiation Through Inhibition of DNA Damage Repair and Increased Pyroptosis
Dose Response. 2024 Apr 11;22(2):15593258241245804. doi: 10.1177/15593258241245804. eCollection 2024 Apr-Jun.ABSTRACTRadiation therapy has been a critical and effective treatment for cancer. However, not all cells are destroyed by radiation due to the presence of tumor cell radioresistance. In the current study, we investigated the effect of low-dose radiation (LDR) on the tumor suppressive effect of high-dose radiation (HDR) and its mechanism from the perspective of tumor cell death mode and DNA damage repair, aiming to provide a foundation for improving the efficacy of clinical tumor radiotherapy. We found that LDR pre-i...
Source: Dose Response - April 15, 2024 Category: Drugs & Pharmacology Authors: Xinfeng Wei Junxuan Yi Citong Zhang Mingwei Wang Rui Wang Weiqiang Xu Mingqi Zhao Mengdie Zhao Teng Yang Wei Wei Shunzi Jin Hui Gao Source Type: research
Dose-Response Study of Caffeine on Postnatal Weight Gain in Premature Neonates-A Retrospective Cohort Study
CONCLUSION: Exposure to higher caffeine doses in this study cohort is associated with lower postnatal WG in preterm neonates than standard daily doses may be due to its catabolic effects and CC-APSEs.PMID:38617389 | PMC:PMC11016235 | DOI:10.1177/15593258241247185 (Source: Dose Response)
Source: Dose Response - April 15, 2024 Category: Drugs & Pharmacology Authors: Ijaz Hussain Manoj Kumar Amin Ali Fizzah Naz Wasif Ahmed Khan Muhammad Sohail Salat Shahzad Rauf Gul Ambreen Kashif Hussain Source Type: research
Enhancement of the Tumor Suppression Effect of High-dose Radiation by Low-dose Pre-radiation Through Inhibition of DNA Damage Repair and Increased Pyroptosis
Dose Response. 2024 Apr 11;22(2):15593258241245804. doi: 10.1177/15593258241245804. eCollection 2024 Apr-Jun.ABSTRACTRadiation therapy has been a critical and effective treatment for cancer. However, not all cells are destroyed by radiation due to the presence of tumor cell radioresistance. In the current study, we investigated the effect of low-dose radiation (LDR) on the tumor suppressive effect of high-dose radiation (HDR) and its mechanism from the perspective of tumor cell death mode and DNA damage repair, aiming to provide a foundation for improving the efficacy of clinical tumor radiotherapy. We found that LDR pre-i...
Source: Dose Response - April 15, 2024 Category: Drugs & Pharmacology Authors: Xinfeng Wei Junxuan Yi Citong Zhang Mingwei Wang Rui Wang Weiqiang Xu Mingqi Zhao Mengdie Zhao Teng Yang Wei Wei Shunzi Jin Hui Gao Source Type: research
Dose-Response Study of Caffeine on Postnatal Weight Gain in Premature Neonates-A Retrospective Cohort Study
CONCLUSION: Exposure to higher caffeine doses in this study cohort is associated with lower postnatal WG in preterm neonates than standard daily doses may be due to its catabolic effects and CC-APSEs.PMID:38617389 | PMC:PMC11016235 | DOI:10.1177/15593258241247185 (Source: Dose Response)
Source: Dose Response - April 15, 2024 Category: Drugs & Pharmacology Authors: Ijaz Hussain Manoj Kumar Amin Ali Fizzah Naz Wasif Ahmed Khan Muhammad Sohail Salat Shahzad Rauf Gul Ambreen Kashif Hussain Source Type: research
Probing Effect of 6 MeV Electron Beam Irradiation on Haemoglobin Protein Using Spectroscopic Techniques
Dose Response. 2024 Apr 1;22(2):15593258241240233. doi: 10.1177/15593258241240233. eCollection 2024 Apr-Jun.ABSTRACTIn this work, we study the effect of 6 MeV electron beam irradiation on the physicochemical properties of lyophilized Human Haemoglobin A (HbA). Electron beams generated from Race Track Microtron accelerator with energy 6 MeV were used to irradiate HbA at fluences of 5 × 1014 e-/cm2 and 10 × 1014 e-/cm2. Pristine and electron beam irradiated HbA were characterized using UV-visible and Fourier transform infrared spectroscopy (FTIR) spectroscopy. The interfacial tension of the aqueous solutions of HbA are als...
Source: Dose Response - April 5, 2024 Category: Drugs & Pharmacology Authors: Sarika Hinge Sanjay Dhole Arun Banpurkar Gauri Kulkarni Source Type: research
Probing Effect of 6 MeV Electron Beam Irradiation on Haemoglobin Protein Using Spectroscopic Techniques
Dose Response. 2024 Apr 1;22(2):15593258241240233. doi: 10.1177/15593258241240233. eCollection 2024 Apr-Jun.ABSTRACTIn this work, we study the effect of 6 MeV electron beam irradiation on the physicochemical properties of lyophilized Human Haemoglobin A (HbA). Electron beams generated from Race Track Microtron accelerator with energy 6 MeV were used to irradiate HbA at fluences of 5 × 1014 e-/cm2 and 10 × 1014 e-/cm2. Pristine and electron beam irradiated HbA were characterized using UV-visible and Fourier transform infrared spectroscopy (FTIR) spectroscopy. The interfacial tension of the aqueous solutions of HbA are als...
Source: Dose Response - April 5, 2024 Category: Drugs & Pharmacology Authors: Sarika Hinge Sanjay Dhole Arun Banpurkar Gauri Kulkarni Source Type: research
Probing Effect of 6 MeV Electron Beam Irradiation on Haemoglobin Protein Using Spectroscopic Techniques
Dose Response. 2024 Apr 1;22(2):15593258241240233. doi: 10.1177/15593258241240233. eCollection 2024 Apr-Jun.ABSTRACTIn this work, we study the effect of 6 MeV electron beam irradiation on the physicochemical properties of lyophilized Human Haemoglobin A (HbA). Electron beams generated from Race Track Microtron accelerator with energy 6 MeV were used to irradiate HbA at fluences of 5 × 1014 e-/cm2 and 10 × 1014 e-/cm2. Pristine and electron beam irradiated HbA were characterized using UV-visible and Fourier transform infrared spectroscopy (FTIR) spectroscopy. The interfacial tension of the aqueous solutions of HbA are als...
Source: Dose Response - April 5, 2024 Category: Drugs & Pharmacology Authors: Sarika Hinge Sanjay Dhole Arun Banpurkar Gauri Kulkarni Source Type: research
Probing Effect of 6 MeV Electron Beam Irradiation on Haemoglobin Protein Using Spectroscopic Techniques
Dose Response. 2024 Apr 1;22(2):15593258241240233. doi: 10.1177/15593258241240233. eCollection 2024 Apr-Jun.ABSTRACTIn this work, we study the effect of 6 MeV electron beam irradiation on the physicochemical properties of lyophilized Human Haemoglobin A (HbA). Electron beams generated from Race Track Microtron accelerator with energy 6 MeV were used to irradiate HbA at fluences of 5 × 1014 e-/cm2 and 10 × 1014 e-/cm2. Pristine and electron beam irradiated HbA were characterized using UV-visible and Fourier transform infrared spectroscopy (FTIR) spectroscopy. The interfacial tension of the aqueous solutions of HbA are als...
Source: Dose Response - April 5, 2024 Category: Drugs & Pharmacology Authors: Sarika Hinge Sanjay Dhole Arun Banpurkar Gauri Kulkarni Source Type: research
Probing Effect of 6 MeV Electron Beam Irradiation on Haemoglobin Protein Using Spectroscopic Techniques
Dose Response. 2024 Apr 1;22(2):15593258241240233. doi: 10.1177/15593258241240233. eCollection 2024 Apr-Jun.ABSTRACTIn this work, we study the effect of 6 MeV electron beam irradiation on the physicochemical properties of lyophilized Human Haemoglobin A (HbA). Electron beams generated from Race Track Microtron accelerator with energy 6 MeV were used to irradiate HbA at fluences of 5 × 1014 e-/cm2 and 10 × 1014 e-/cm2. Pristine and electron beam irradiated HbA were characterized using UV-visible and Fourier transform infrared spectroscopy (FTIR) spectroscopy. The interfacial tension of the aqueous solutions of HbA are als...
Source: Dose Response - April 5, 2024 Category: Drugs & Pharmacology Authors: Sarika Hinge Sanjay Dhole Arun Banpurkar Gauri Kulkarni Source Type: research
Probing Effect of 6 MeV Electron Beam Irradiation on Haemoglobin Protein Using Spectroscopic Techniques
Dose Response. 2024 Apr 1;22(2):15593258241240233. doi: 10.1177/15593258241240233. eCollection 2024 Apr-Jun.ABSTRACTIn this work, we study the effect of 6 MeV electron beam irradiation on the physicochemical properties of lyophilized Human Haemoglobin A (HbA). Electron beams generated from Race Track Microtron accelerator with energy 6 MeV were used to irradiate HbA at fluences of 5 × 1014 e-/cm2 and 10 × 1014 e-/cm2. Pristine and electron beam irradiated HbA were characterized using UV-visible and Fourier transform infrared spectroscopy (FTIR) spectroscopy. The interfacial tension of the aqueous solutions of HbA are als...
Source: Dose Response - April 5, 2024 Category: Drugs & Pharmacology Authors: Sarika Hinge Sanjay Dhole Arun Banpurkar Gauri Kulkarni Source Type: research
Probing Effect of 6 MeV Electron Beam Irradiation on Haemoglobin Protein Using Spectroscopic Techniques
Dose Response. 2024 Apr 1;22(2):15593258241240233. doi: 10.1177/15593258241240233. eCollection 2024 Apr-Jun.ABSTRACTIn this work, we study the effect of 6 MeV electron beam irradiation on the physicochemical properties of lyophilized Human Haemoglobin A (HbA). Electron beams generated from Race Track Microtron accelerator with energy 6 MeV were used to irradiate HbA at fluences of 5 × 1014 e-/cm2 and 10 × 1014 e-/cm2. Pristine and electron beam irradiated HbA were characterized using UV-visible and Fourier transform infrared spectroscopy (FTIR) spectroscopy. The interfacial tension of the aqueous solutions of HbA are als...
Source: Dose Response - April 5, 2024 Category: Drugs & Pharmacology Authors: Sarika Hinge Sanjay Dhole Arun Banpurkar Gauri Kulkarni Source Type: research
Probing Effect of 6 MeV Electron Beam Irradiation on Haemoglobin Protein Using Spectroscopic Techniques
Dose Response. 2024 Apr 1;22(2):15593258241240233. doi: 10.1177/15593258241240233. eCollection 2024 Apr-Jun.ABSTRACTIn this work, we study the effect of 6 MeV electron beam irradiation on the physicochemical properties of lyophilized Human Haemoglobin A (HbA). Electron beams generated from Race Track Microtron accelerator with energy 6 MeV were used to irradiate HbA at fluences of 5 × 1014 e-/cm2 and 10 × 1014 e-/cm2. Pristine and electron beam irradiated HbA were characterized using UV-visible and Fourier transform infrared spectroscopy (FTIR) spectroscopy. The interfacial tension of the aqueous solutions of HbA are als...
Source: Dose Response - April 5, 2024 Category: Drugs & Pharmacology Authors: Sarika Hinge Sanjay Dhole Arun Banpurkar Gauri Kulkarni Source Type: research
Condiment Recipes Lead to Reduced Generation of Carcinogenic Polycyclic Aromatic Hydrocarbons in Duck Variety Meat During Charcoal Grilling
Dose Response. 2023 Sep 20;21(3):15593258231203212. doi: 10.1177/15593258231203212. eCollection 2023 Jul-Sep.ABSTRACTThe current study aimed to evaluate the impact of charcoal grilling in the generation of various polycyclic aromatic hydrocarbons in the tissues of 5 different organs (leg, chest, wings, liver, and heart) of falcated ducks (Mareca falcata) before and after pasting them with different condiment recipes (R1, R2, R3, and R4). All condiment-pasted and control samples before/after charcoal grilling were pursued in RP-HPLC for quantification of unknown PAHs. Tissues from grilled raw leg meat of the control sample ...
Source: Dose Response - April 1, 2024 Category: Drugs & Pharmacology Authors: Gulshan Shahid Muhammad Yousaf Haseeb Anwar Imran Mukhtar Abdul Basit Source Type: research
Condiment Recipes Lead to Reduced Generation of Carcinogenic Polycyclic Aromatic Hydrocarbons in Duck Variety Meat During Charcoal Grilling
Dose Response. 2023 Sep 20;21(3):15593258231203212. doi: 10.1177/15593258231203212. eCollection 2023 Jul-Sep.ABSTRACTThe current study aimed to evaluate the impact of charcoal grilling in the generation of various polycyclic aromatic hydrocarbons in the tissues of 5 different organs (leg, chest, wings, liver, and heart) of falcated ducks (Mareca falcata) before and after pasting them with different condiment recipes (R1, R2, R3, and R4). All condiment-pasted and control samples before/after charcoal grilling were pursued in RP-HPLC for quantification of unknown PAHs. Tissues from grilled raw leg meat of the control sample ...
Source: Dose Response - April 1, 2024 Category: Drugs & Pharmacology Authors: Gulshan Shahid Muhammad Yousaf Haseeb Anwar Imran Mukhtar Abdul Basit Source Type: research
Condiment Recipes Lead to Reduced Generation of Carcinogenic Polycyclic Aromatic Hydrocarbons in Duck Variety Meat During Charcoal Grilling
Dose Response. 2023 Sep 20;21(3):15593258231203212. doi: 10.1177/15593258231203212. eCollection 2023 Jul-Sep.ABSTRACTThe current study aimed to evaluate the impact of charcoal grilling in the generation of various polycyclic aromatic hydrocarbons in the tissues of 5 different organs (leg, chest, wings, liver, and heart) of falcated ducks (Mareca falcata) before and after pasting them with different condiment recipes (R1, R2, R3, and R4). All condiment-pasted and control samples before/after charcoal grilling were pursued in RP-HPLC for quantification of unknown PAHs. Tissues from grilled raw leg meat of the control sample ...
Source: Dose Response - April 1, 2024 Category: Drugs & Pharmacology Authors: Gulshan Shahid Muhammad Yousaf Haseeb Anwar Imran Mukhtar Abdul Basit Source Type: research
