Evaluation and Validation of a New Score to Measure the Severity of Small Bowel Angiodysplasia on Video Capsule Endoscopy.
It's not mentioned in author guidelines' section that is mandatory to write an abstract for a letter to the editor. (Source: Digestive Diseases)
Source: Digestive Diseases - April 11, 2023 Category: Gastroenterology Source Type: research

Anemia is associated with disease severity, hepatic complications, and progression of Wilson disease: a retrospective cohort study
Introduction: Anemia is a common manifestation of chronic liver diseases. It is a predictor of severe disease, a high risk of complications, and poor outcomes in various liver diseases. However, it remains unclear whether anemia serves as a similar indicator in patients with Wilson disease (WD). Therefore, this study aimed to investigate the relationship between anemia and severity, hepatic complications, and the progression of WD. Methods: Medical data were collected retrospectively from January 1, 2016, to December 31, 2020. Univariate and multivariate analyses were carried out to investigate the relationship between ane...
Source: Digestive Diseases - April 5, 2023 Category: Gastroenterology Source Type: research

Gastroduodenal ulcers in liver transplant recipients under immunosuppressive therapy
Conclusion Patients treated with immunosuppressive drugs after liver transplantation can develop gastroduodenal ulcers, even with gastric acid suppressant medication. Mycophenolate mofetil may incre ase the risk of gastroduodenal ulcers compared with other immunosuppressive drugs. (Source: Digestive Diseases)
Source: Digestive Diseases - April 5, 2023 Category: Gastroenterology Source Type: research

Early predictors of infected pancreatic necrosis in acute severe pancreatitis – Implications of neutrophil to lymphocyte ratio, blood procalcitonin concentration and modified CT severity index
This study aimed to evaluate the predicting value for IPN of combined markers at early stages of SAP. Methods: The clincial records of 324 SAP patients admitted within 48 hours after disease onset were retrospectively analyzed. As potential predictors, the neutrophil to lymphocyte ratio (NLR), blood procalcitonin concentration (PCT) on the 1st, 4th and 7th day post admission, as well as modified computerized tomography severity index (MCTSI) on the 5 – 7th day post admission, were extracted. Correlations between these features with IPN were analyzed using logistic regression, and predictive values were estimated using t...
Source: Digestive Diseases - March 30, 2023 Category: Gastroenterology Source Type: research

Factors related to difficulty in endoscopic submucosal dissection for superficial esophageal cancer
This study aimed to investigate the factors predicting the difficulty in esophageal ESD. Methods: This retrospective study analyzed 303 lesions treated at our institution between April 2005 and June 2021. The following 13 factors were evaluated: sex, age, tumor location, tumor localization, macroscopic type, tumor size, tumor circumference, preoperative diagnosis of histological type, preoperative diagnosis of invasion depth, previous radiotherapy for esophageal cancer, metachronous lesion located close to post ESD scar, operator ’s skill, and use of a clip-and-thread traction method. Difficult esophageal ESD cases were...
Source: Digestive Diseases - March 29, 2023 Category: Gastroenterology Source Type: research

Uncovering the Silent Killer: Research highlights on chronic liver diseases
Chronic liver disease (CLD) affects approximately 1.5 billion people around the world.1 Non-alcoholic fatty liver disease (NAFLD) is the most common CLD that accounts for 59% of prevalent cases, followed by hepatitis B virus (HBV) infection (29%) and hepatitis C virus infection (9%).2 CLD is a silent killer characterized by insidious progression in hepatic necroinflammation and fibrosis that can culminate in cirrhosis and increase the risk of primary liver cancer. According to the Global Burden of Disease study, there were 2.1 million deaths attributable to CLD in 2017, with cirrhosis and liver cancer respectively responsi...
Source: Digestive Diseases - March 28, 2023 Category: Gastroenterology Source Type: research

Insights from an exploratory retrospective cohort study: Are face-to-face follow-up consultations after colonoscopy a thing of the past
Conclusion If such “unnecessary” post-colonoscopy consultation s exist within our institution, then similar situations possibly occur elsewhere. As COVID-19 continues to periodically tax healthcare systems worldwide, preservation of resources will remain integral alongside quality standards of routine patient care. There is a need for detailed analyses and mode lling to hypothesise potential savings by also considering the start-up and maintenance costs of switching to a teleconsultation-dominated system. (Source: Digestive Diseases)
Source: Digestive Diseases - March 24, 2023 Category: Gastroenterology Source Type: research

Characteristics and Outcomes of Elderly Hepatocellular Carcinoma Patients following Surgical Resection: Systematic Review and Meta-analysis
Conclusion: This data shows that overall survival, recurrence and major complications after liver resection for HCC are comparable between elderly and non-elderly patients, and may inform clinical management of HCC in this population. (Source: Digestive Diseases)
Source: Digestive Diseases - March 13, 2023 Category: Gastroenterology Source Type: research

< i > Helicobacter pylori < /i > Infection as a Predictor of Treatment Outcomes of Gastric Cancer: A Systematic Review and Meta-Analysis
Conclusion:H. pylori-positive gastric cancer patients have a better overall prognosis thanH. pylori-negative patients.H. pylori infection has improved the prognosis of patients undergoing surgery or chemotherapy, among which the improvement was most obvious in patients undergoing surgery combined with chemotherapy. (Source: Digestive Diseases)
Source: Digestive Diseases - March 10, 2023 Category: Gastroenterology Source Type: research

Helicobacter pylori infection as predictor of treatment outcomes of gastric cancer: a systematic review and metanalysis
Conclusions: H. pylori-positive gastric cancer patients have a better overall prognosis than negative patients. Helicobacter pylori infection has improved the prognosis of patients undergoing surgery or chemotherapy, among which the improvement was most obvious in patients undergoing surgery combined with chemotherapy. (Source: Digestive Diseases)
Source: Digestive Diseases - March 10, 2023 Category: Gastroenterology Source Type: research

Therapeutic Plasma Exchange in ICU patients with acute hypertriglyceridemia-induced pancreatitis improves patient outcomes
Background: Acute severe pancreatitis is associated with high morbidity and mortality. Hypertriglyceridemia is the third most common cause of acute pancreatitis and higher triglyceride levels increase the risk for severe acute pancreatitis. Plasma exchange is an effective treatment method to lower triglycerides. Our study aimed to investigate the efficiency of plasma exchange as a treatment option for acute hypertriglyceridemia-induced pancreatitis (HTGP), the impact on mortality assessed by the SOFA-, SAPS II-, BISAP Score, Ranson ’s, and Glasgow-Imrie Criteria as well as the overall length of stay in hospital and ICU. ...
Source: Digestive Diseases - March 4, 2023 Category: Gastroenterology Source Type: research

The Role of Fecal Microbiota Transplantation in the Induction of Remission in Ulcerative Colitis
Background: Considerable research supports an important role for the microbiome and/or microbiome –host immune system interactions in the pathogenesis of inflammatory bowel disease (IBD). Consequently, microbiota-modulating interventions, such as fecal microbiota transplantation (FMT), have attracted interest in the management of IBD, including ulcerative colitis (UC). Summary: While the clini cal response to FMT in UC has varied between different studies, results to date may offer guidance towards optimal use of FMT. Thus, increased microbiome biodiversity, the presence of short-chain fatty acid producing bacteria, Clos...
Source: Digestive Diseases - March 1, 2023 Category: Gastroenterology Source Type: research