Targeting TNF- α-induced expression of TTR and RAGE in rheumatoid arthritis: Apigenin's mediated therapeutic approach
CONCLUSION: The findings of this study suggested that TNF-α promotes the differential expression of pro-inflammatory cytokines, TTR, and RAGE via NF-kB pathways activation. Anti-inflammatory effect of apigenin impedes TNF-α mediated dysregulation or expression associated with RA pathogenesis.PMID:38626647 | DOI:10.1016/j.cyto.2024.156616 (Source: Cytokine)
Source: Cytokine - April 16, 2024 Category: Molecular Biology Authors: None Monu Prachi Agnihotri Mohd Saquib Sagarika Biswas Source Type: research
The sex-dependent impact of adipose tissue and inflammation on chronic pain - A cross-sectional study from the all of us research program
This article investigates the relationship between chronic pain, obesity, and inflammatory markers. It could help elucidating sex difference in pain mechanisms, as well as the risk factors for chronic pain, potentially improving patient diagnosis, follow-up and treatment.PMID:38621331 | DOI:10.1016/j.cyto.2024.156614 (Source: Cytokine)
Source: Cytokine - April 15, 2024 Category: Molecular Biology Authors: Deepak Berwal Dumitru D Branisteanu Mia Glickman Amit Sagar Julie G Pilitsis Source Type: research
Recombinant human IL-37 attenuates acute cardiac allograft rejection in mice
CONCLUSIONS: We demonstrated that rhIL-37 effectively suppress acute rejection and induce long-term allograft acceptance. The results highlight that IL-37 could be novel and promising candidate for prevention of allograft rejection.PMID:38583255 | DOI:10.1016/j.cyto.2024.156598 (Source: Cytokine)
Source: Cytokine - April 7, 2024 Category: Molecular Biology Authors: Bo Shao Jing-Yi Zhang Shao-Hua Ren Ya-Fei Qin Hong-da Wang Yong-Chang Gao De-Jun Kong Yong-Hao Hu Hong Qin Guang-Ming Li Hao Wang Source Type: research
Recombinant human IL-37 attenuates acute cardiac allograft rejection in mice
CONCLUSIONS: We demonstrated that rhIL-37 effectively suppress acute rejection and induce long-term allograft acceptance. The results highlight that IL-37 could be novel and promising candidate for prevention of allograft rejection.PMID:38583255 | DOI:10.1016/j.cyto.2024.156598 (Source: Cytokine)
Source: Cytokine - April 7, 2024 Category: Molecular Biology Authors: Bo Shao Jing-Yi Zhang Shao-Hua Ren Ya-Fei Qin Hong-da Wang Yong-Chang Gao De-Jun Kong Yong-Hao Hu Hong Qin Guang-Ming Li Hao Wang Source Type: research
Recombinant human IL-37 attenuates acute cardiac allograft rejection in mice
CONCLUSIONS: We demonstrated that rhIL-37 effectively suppress acute rejection and induce long-term allograft acceptance. The results highlight that IL-37 could be novel and promising candidate for prevention of allograft rejection.PMID:38583255 | DOI:10.1016/j.cyto.2024.156598 (Source: Cytokine)
Source: Cytokine - April 7, 2024 Category: Molecular Biology Authors: Bo Shao Jing-Yi Zhang Shao-Hua Ren Ya-Fei Qin Hong-da Wang Yong-Chang Gao De-Jun Kong Yong-Hao Hu Hong Qin Guang-Ming Li Hao Wang Source Type: research
Recombinant human IL-37 attenuates acute cardiac allograft rejection in mice
CONCLUSIONS: We demonstrated that rhIL-37 effectively suppress acute rejection and induce long-term allograft acceptance. The results highlight that IL-37 could be novel and promising candidate for prevention of allograft rejection.PMID:38583255 | DOI:10.1016/j.cyto.2024.156598 (Source: Cytokine)
Source: Cytokine - April 7, 2024 Category: Molecular Biology Authors: Bo Shao Jing-Yi Zhang Shao-Hua Ren Ya-Fei Qin Hong-da Wang Yong-Chang Gao De-Jun Kong Yong-Hao Hu Hong Qin Guang-Ming Li Hao Wang Source Type: research
Recombinant human IL-37 attenuates acute cardiac allograft rejection in mice
CONCLUSIONS: We demonstrated that rhIL-37 effectively suppress acute rejection and induce long-term allograft acceptance. The results highlight that IL-37 could be novel and promising candidate for prevention of allograft rejection.PMID:38583255 | DOI:10.1016/j.cyto.2024.156598 (Source: Cytokine)
Source: Cytokine - April 7, 2024 Category: Molecular Biology Authors: Bo Shao Jing-Yi Zhang Shao-Hua Ren Ya-Fei Qin Hong-da Wang Yong-Chang Gao De-Jun Kong Yong-Hao Hu Hong Qin Guang-Ming Li Hao Wang Source Type: research
Recombinant human IL-37 attenuates acute cardiac allograft rejection in mice
CONCLUSIONS: We demonstrated that rhIL-37 effectively suppress acute rejection and induce long-term allograft acceptance. The results highlight that IL-37 could be novel and promising candidate for prevention of allograft rejection.PMID:38583255 | DOI:10.1016/j.cyto.2024.156598 (Source: Cytokine)
Source: Cytokine - April 7, 2024 Category: Molecular Biology Authors: Bo Shao Jing-Yi Zhang Shao-Hua Ren Ya-Fei Qin Hong-da Wang Yong-Chang Gao De-Jun Kong Yong-Hao Hu Hong Qin Guang-Ming Li Hao Wang Source Type: research
Expression and function of cytokine interleukin-22 gene in the tumor microenvironment of triple negative breast cancer
CONCLUSION: The findings suggested that targeting IL-22 and its related pathways can offer new insights for developing effective therapies for TNBC.PMID:38581864 | DOI:10.1016/j.cyto.2024.156590 (Source: Cytokine)
Source: Cytokine - April 6, 2024 Category: Molecular Biology Authors: Yibin Xiao Xia Zhao Yihui Guo Yanping Li Source Type: research
Low expression of interleukin-1 receptor antagonist correlates with poor prognosis via promoting proliferation and migration and inhibiting apoptosis in oral squamous cell carcinoma
CONCLUSIONS: In summary, our investigation highlighted the possible involvement of low-expression IL1RA in OSCC cells in promoting invasive as well as metastatic and inhibiting apoptosis, as well as the efficacy of IL1RA-focused monitoring in the early detection and treatment of OSCC.PMID:38581865 | DOI:10.1016/j.cyto.2024.156595 (Source: Cytokine)
Source: Cytokine - April 6, 2024 Category: Molecular Biology Authors: Yujie Ding Jie Yi Yufei Shan Jiaqi Gu Zhida Sun Jie Lin Source Type: research
Diagnostic, monitoring, and prognostic value of combined detection of cerebrospinal fluid heparin-binding protein, interleukin-6, interleukin-10, and procalcitonin for post-neurosurgical intracranial infection
CONCLUSION: The combined detection can be an important indicator for the diagnosis and disease monitoring of post-neurosurgical intracranial infection.PMID:38581866 | DOI:10.1016/j.cyto.2024.156593 (Source: Cytokine)
Source: Cytokine - April 6, 2024 Category: Molecular Biology Authors: Xinfang Pan Dina Haishaer Mei Liu Shaobo Zhou Heya Na Hongmei Zhao Source Type: research
Establishment of reference intervals for plasma IL-2, IL-4, IL-5, and IL-17A in healthy adults from the Jiangsu region of eastern China using flow cytometry: A single-center study
CONCLUSIONS: We first established the reference intervals of plasma IL-2, IL-4, IL-5 and IL-17A in healthy adults based on a single-center population in the Jiangsu region in eastern China, which will provide an important reference value for evaluating human immune status and the diagnosis and treatment of clinical diseases.PMID:38581867 | DOI:10.1016/j.cyto.2024.156594 (Source: Cytokine)
Source: Cytokine - April 6, 2024 Category: Molecular Biology Authors: Qian Liu Zhengping Xia Tingting Huang Fang Yang Xizhen Wang Fumeng Yang Source Type: research
Expression and function of cytokine interleukin-22 gene in the tumor microenvironment of triple negative breast cancer
CONCLUSION: The findings suggested that targeting IL-22 and its related pathways can offer new insights for developing effective therapies for TNBC.PMID:38581864 | DOI:10.1016/j.cyto.2024.156590 (Source: Cytokine)
Source: Cytokine - April 6, 2024 Category: Molecular Biology Authors: Yibin Xiao Xia Zhao Yihui Guo Yanping Li Source Type: research
Low expression of interleukin-1 receptor antagonist correlates with poor prognosis via promoting proliferation and migration and inhibiting apoptosis in oral squamous cell carcinoma
CONCLUSIONS: In summary, our investigation highlighted the possible involvement of low-expression IL1RA in OSCC cells in promoting invasive as well as metastatic and inhibiting apoptosis, as well as the efficacy of IL1RA-focused monitoring in the early detection and treatment of OSCC.PMID:38581865 | DOI:10.1016/j.cyto.2024.156595 (Source: Cytokine)
Source: Cytokine - April 6, 2024 Category: Molecular Biology Authors: Yujie Ding Jie Yi Yufei Shan Jiaqi Gu Zhida Sun Jie Lin Source Type: research
Diagnostic, monitoring, and prognostic value of combined detection of cerebrospinal fluid heparin-binding protein, interleukin-6, interleukin-10, and procalcitonin for post-neurosurgical intracranial infection
CONCLUSION: The combined detection can be an important indicator for the diagnosis and disease monitoring of post-neurosurgical intracranial infection.PMID:38581866 | DOI:10.1016/j.cyto.2024.156593 (Source: Cytokine)
Source: Cytokine - April 6, 2024 Category: Molecular Biology Authors: Xinfang Pan Dina Haishaer Mei Liu Shaobo Zhou Heya Na Hongmei Zhao Source Type: research
