Longitudinal Changes in Refractive Development in Highly Hyperopic Children: A 2.6-11.2 Year Follow-up of Preschoolers Diagnosed with High Hyperopia
CONCLUSION: Highly hyperopic preschool children undergoing early intervention display a marked emmetropization tendency, though most still remain moderately to highly hyperopic, with the progression of refractive changes showing non-uniform patterns with respect to age.PMID:38616539 | DOI:10.1080/02713683.2024.2336162 (Source: Current Eye Research)
Source: Current Eye Research - April 15, 2024 Category: Opthalmology Authors: Ling Sun Xiaoli Qi Linlin Song Yuxian Ning Xiaoyu Zeng Gang Ding Xue Li Jing Li Nan Wei Ning Hua Xuehan Qian Source Type: research

Longitudinal Changes in Refractive Development in Highly Hyperopic Children: A 2.6-11.2 Year Follow-up of Preschoolers Diagnosed with High Hyperopia
CONCLUSION: Highly hyperopic preschool children undergoing early intervention display a marked emmetropization tendency, though most still remain moderately to highly hyperopic, with the progression of refractive changes showing non-uniform patterns with respect to age.PMID:38616539 | DOI:10.1080/02713683.2024.2336162 (Source: Current Eye Research)
Source: Current Eye Research - April 15, 2024 Category: Opthalmology Authors: Ling Sun Xiaoli Qi Linlin Song Yuxian Ning Xiaoyu Zeng Gang Ding Xue Li Jing Li Nan Wei Ning Hua Xuehan Qian Source Type: research

Datasets-Based < em > IMPDH1 < /em > Revisited: Heterozygous Missense Variants for Dominant Retinitis Pigmentosa While Truncation Variants Are Likely Non-Pathogenic
CONCLUSIONS: Our data together with comprehensive analysis of existing datasets suggest that causative variants of IMPDH1 are usually missense and mostly clustered in exons 8-10. Conversely, most missense variants outside this region and truncation variants should be interpreted with great care in clinical gene test.PMID:38604988 | DOI:10.1080/02713683.2024.2336158 (Source: Current Eye Research)
Source: Current Eye Research - April 11, 2024 Category: Opthalmology Authors: Junwen Wang Yingwei Wang Yi Jiang Shiqiang Li Xiaoyun Jia Xueshan Xiao Wenmin Sun Panfeng Wang Qingjiong Zhang Source Type: research

Datasets-Based < em > IMPDH1 < /em > Revisited: Heterozygous Missense Variants for Dominant Retinitis Pigmentosa While Truncation Variants Are Likely Non-Pathogenic
CONCLUSIONS: Our data together with comprehensive analysis of existing datasets suggest that causative variants of IMPDH1 are usually missense and mostly clustered in exons 8-10. Conversely, most missense variants outside this region and truncation variants should be interpreted with great care in clinical gene test.PMID:38604988 | DOI:10.1080/02713683.2024.2336158 (Source: Current Eye Research)
Source: Current Eye Research - April 11, 2024 Category: Opthalmology Authors: Junwen Wang Yingwei Wang Yi Jiang Shiqiang Li Xiaoyun Jia Xueshan Xiao Wenmin Sun Panfeng Wang Qingjiong Zhang Source Type: research

Datasets-Based < em > IMPDH1 < /em > Revisited: Heterozygous Missense Variants for Dominant Retinitis Pigmentosa While Truncation Variants Are Likely Non-Pathogenic
CONCLUSIONS: Our data together with comprehensive analysis of existing datasets suggest that causative variants of IMPDH1 are usually missense and mostly clustered in exons 8-10. Conversely, most missense variants outside this region and truncation variants should be interpreted with great care in clinical gene test.PMID:38604988 | DOI:10.1080/02713683.2024.2336158 (Source: Current Eye Research)
Source: Current Eye Research - April 11, 2024 Category: Opthalmology Authors: Junwen Wang Yingwei Wang Yi Jiang Shiqiang Li Xiaoyun Jia Xueshan Xiao Wenmin Sun Panfeng Wang Qingjiong Zhang Source Type: research

The Effect of Diabetic Retinopathy and Blood Glucose Regulation on Corneal Biomechanical Parameters
CONCLUSION: This study underscores the influence of metabolic control, as reflected by HbA1c levels, on corneal biomechanical parameters in diabetic patients, emphasizing the importance of monitoring and managing glycemic control in this population.PMID:38587365 | DOI:10.1080/02713683.2024.2338219 (Source: Current Eye Research)
Source: Current Eye Research - April 8, 2024 Category: Opthalmology Authors: Duygu Akbulut Sagaltici Emin Kurt Recep Goktug Seymenoglu Huseyin Mayali Zeliha Hekimsoy Source Type: research

The Effect of Diabetic Retinopathy and Blood Glucose Regulation on Corneal Biomechanical Parameters
CONCLUSION: This study underscores the influence of metabolic control, as reflected by HbA1c levels, on corneal biomechanical parameters in diabetic patients, emphasizing the importance of monitoring and managing glycemic control in this population.PMID:38587365 | DOI:10.1080/02713683.2024.2338219 (Source: Current Eye Research)
Source: Current Eye Research - April 8, 2024 Category: Opthalmology Authors: Duygu Akbulut Sagaltici Emin Kurt Recep Goktug Seymenoglu Huseyin Mayali Zeliha Hekimsoy Source Type: research

The Effect of Diabetic Retinopathy and Blood Glucose Regulation on Corneal Biomechanical Parameters
CONCLUSION: This study underscores the influence of metabolic control, as reflected by HbA1c levels, on corneal biomechanical parameters in diabetic patients, emphasizing the importance of monitoring and managing glycemic control in this population.PMID:38587365 | DOI:10.1080/02713683.2024.2338219 (Source: Current Eye Research)
Source: Current Eye Research - April 8, 2024 Category: Opthalmology Authors: Duygu Akbulut Sagaltici Emin Kurt Recep Goktug Seymenoglu Huseyin Mayali Zeliha Hekimsoy Source Type: research

The Effect of Diabetic Retinopathy and Blood Glucose Regulation on Corneal Biomechanical Parameters
CONCLUSION: This study underscores the influence of metabolic control, as reflected by HbA1c levels, on corneal biomechanical parameters in diabetic patients, emphasizing the importance of monitoring and managing glycemic control in this population.PMID:38587365 | DOI:10.1080/02713683.2024.2338219 (Source: Current Eye Research)
Source: Current Eye Research - April 8, 2024 Category: Opthalmology Authors: Duygu Akbulut Sagaltici Emin Kurt Recep Goktug Seymenoglu Huseyin Mayali Zeliha Hekimsoy Source Type: research

FTY720 Suppresses Pathogenic Retinal M üller Cell Activation and Chronic Progression by Inhibiting the mTOR/NF-κB Signaling Pathway and Regulating Autophagy
CONCLUSIONS: This study suggests that in an HG-induced rMC-1 cell model, FTY720 significantly inhibited the production of inflammatory cytokines by inhibiting mTOR/NF-κB signaling and regulating autophagy. These findings were associated with a decrease in rMC-1 cell injury, suggesting that FTY720 or related compounds may be valuable modulators of HG-induced retinal injury.PMID:38577836 | DOI:10.1080/02713683.2024.2337301 (Source: Current Eye Research)
Source: Current Eye Research - April 5, 2024 Category: Opthalmology Authors: Yanting Yang Yan Liu Huan Tang Qing Zhou Huanhuan Li E Song Source Type: research

Comment: Low Vision Referral Patterns in Intermediate Age-Related Macular Degeneration
Curr Eye Res. 2024 Apr 5:1-2. doi: 10.1080/02713683.2024.2337297. Online ahead of print.NO ABSTRACTPMID:38577852 | DOI:10.1080/02713683.2024.2337297 (Source: Current Eye Research)
Source: Current Eye Research - April 5, 2024 Category: Opthalmology Authors: Suraj Kumar Chaurasiya Mahendra Singh Ashish Chander Radhika Pushkar Source Type: research

FTY720 Suppresses Pathogenic Retinal M üller Cell Activation and Chronic Progression by Inhibiting the mTOR/NF-κB Signaling Pathway and Regulating Autophagy
CONCLUSIONS: This study suggests that in an HG-induced rMC-1 cell model, FTY720 significantly inhibited the production of inflammatory cytokines by inhibiting mTOR/NF-κB signaling and regulating autophagy. These findings were associated with a decrease in rMC-1 cell injury, suggesting that FTY720 or related compounds may be valuable modulators of HG-induced retinal injury.PMID:38577836 | DOI:10.1080/02713683.2024.2337301 (Source: Current Eye Research)
Source: Current Eye Research - April 5, 2024 Category: Opthalmology Authors: Yanting Yang Yan Liu Huan Tang Qing Zhou Huanhuan Li E Song Source Type: research

Comment: Low Vision Referral Patterns in Intermediate Age-Related Macular Degeneration
Curr Eye Res. 2024 Apr 5:1-2. doi: 10.1080/02713683.2024.2337297. Online ahead of print.NO ABSTRACTPMID:38577852 | DOI:10.1080/02713683.2024.2337297 (Source: Current Eye Research)
Source: Current Eye Research - April 5, 2024 Category: Opthalmology Authors: Suraj Kumar Chaurasiya Mahendra Singh Ashish Chander Radhika Pushkar Source Type: research

FTY720 Suppresses Pathogenic Retinal M üller Cell Activation and Chronic Progression by Inhibiting the mTOR/NF-κB Signaling Pathway and Regulating Autophagy
CONCLUSIONS: This study suggests that in an HG-induced rMC-1 cell model, FTY720 significantly inhibited the production of inflammatory cytokines by inhibiting mTOR/NF-κB signaling and regulating autophagy. These findings were associated with a decrease in rMC-1 cell injury, suggesting that FTY720 or related compounds may be valuable modulators of HG-induced retinal injury.PMID:38577836 | DOI:10.1080/02713683.2024.2337301 (Source: Current Eye Research)
Source: Current Eye Research - April 5, 2024 Category: Opthalmology Authors: Yanting Yang Yan Liu Huan Tang Qing Zhou Huanhuan Li E Song Source Type: research

Comment: Low Vision Referral Patterns in Intermediate Age-Related Macular Degeneration
Curr Eye Res. 2024 Apr 5:1-2. doi: 10.1080/02713683.2024.2337297. Online ahead of print.NO ABSTRACTPMID:38577852 | DOI:10.1080/02713683.2024.2337297 (Source: Current Eye Research)
Source: Current Eye Research - April 5, 2024 Category: Opthalmology Authors: Suraj Kumar Chaurasiya Mahendra Singh Ashish Chander Radhika Pushkar Source Type: research